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# Program: MUSTANG v0.2: A Multiple structural alignment algorithm
# Authors: A. S. Konagurthu, P. J. Stuckey, J. C. Whisstock, and A. M. Lesk
# Rundate: Tue Oct 4 16:45:35 2005
# Report_file: results.html
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#====================================
# Aligned_structures: 13
# 1: 3EST.pdb
# 2: 2PKA.pdb
# 3: 1TON.pdb
# 4: 3RP2.pdb
# 5: 4PTP.pdb
# 6: 5CHA.pdb
# 7: 1PPB.pdb
# 8: 1SGT.pdb
# 9: 1ARB.pdb
# 10: 2SGA.pdb
# 11: 3SGB.pdb
# 12: 2ALP.pdb
# 13: 2SNV.pdb
#
# Length: 421
# Identity: 5/421 ( 1.2%) (Calculated as the percentage of conserved columns in the alignment.)
# Similarity: 11/421 ( 2.6%) (Calculated as the percentage of semi-conserved columns in the alignment)
# Gaps: 302/421 ( 71.7%) (Calculated as the percentage of columns with atleast one gap.)
#===========================================ALIGNMENT START=========================================
3EST.pdb 1 -----------------------------------------VVGGTEAQ-RNS------- 11
2PKA.pdb 1 -----------------------------------------IIGGRECE-KNS------- 11
1TON.pdb 1 -----------------------------------------IVGGYKCE-KNS------- 11
3RP2.pdb 1 -----------------------------------------IIGGVESI-PHS------- 11
4PTP.pdb 1 -----------------------------------------IVGGYTCG-ANT------- 11
5CHA.pdb 1 -----------CGVPAIQPV---------------------IVNGEEAV-PGS------- 20
1PPB.pdb 1 ---TFGSGEADCGLRPLF--EKKSLEDKTERELLESYIDGRIVEGSDAE-IGM------- 47
1SGT.pdb 1 -----------------------------------------VVGGTRAA-QGE------- 11
1ARB.pdb 1 GVS--------------------------------------GSCNIDVVCP--EGDGRRD 20
2SGA.pdb ------------------------------------------------------------
3SGB.pdb ------------------------------------------------------------
2ALP.pdb ------------------------------------------------------------
2SNV.pdb ------------------------------------------------------------
3EST.pdb 12 ----WPSQISLQYRSGS-SW-AHTCGGTL-IR----Q--NWVMTAAHCV-----D----- 48
2PKA.pdb 12 ----HPWQVAIYHY-----S-SFQCGGVL-VN----P--KWVLTAAHCK-----N----- 44
1TON.pdb 12 ----QPWQVAVIN------E--YLCGGVL-ID----P--SWVITAAHCY-----S----- 42
3RP2.pdb 12 ----RPYMAHLDIVT--EKGLRVICGGFL-IS----R--QFVLTAAHCK-----G----- 48
4PTP.pdb 12 ----VPYQVSLNS------G-YHFCGGSL-IN----S--QWVVSAAHCY-----K----- 43
5CHA.pdb 21 ----WPWQVSLQDK----TG-FHFCGGSL-IN----E--NWVVTAAHCG----------- 53
1PPB.pdb 48 ----SPWQVMLFRKS---PQ-ELLCGASL-IS----D--RWVLTAAHCL-----L----Y 83
1SGT.pdb 12 ----FPFMVRLS----------MGCGGAL-YA----Q--DIVLTAAHCV-----SGSGN- 44
1ARB.pdb 21 I---IRAVGAYSKS----G--TLACTGSLVNNTAN-DRKMYFLTAHHCGMGTAST----- 65
2SGA.pdb 1 ---IA-GGEAITTG-------GSRCSLGFNVS---VNGVAHALTAGHCT-----N----- 36
3SGB.pdb 1 ---IS-GGDAIYSS-------TGRCSLGFNVR---SGSTYYFLTAGHCT-----D----- 36
2ALP.pdb 1 -ANIV-GGIEYSIN----N--ASLCSVGFSVT---RGATKGFVTAGHCG-----T----- 39
2SNV.pdb 1 ------RLFDVKNE----DG-DVIGHALAME--------GKVMKPLHVK----------- 30
c a Hc
3EST.pdb 49 --------RELTFRVVV-GEH-----NLNQN---------N-GTEQYVGVQKIVVHPYWN 84
2PKA.pdb 45 ----------DNYEVWL-GRH-----NLFEN---------E-NTAQFFGVTADFPHPGFN 78
1TON.pdb 43 ----------NNYQVLL-GRN-----NLFKD---------E-PFAQRRLVRQSFRHPDYI 76
3RP2.pdb 49 ----------REITVIL-GAH-----DVRKR---------E-STQQKIKVEKQIIHESYN 82
4PTP.pdb 44 ----------SGIQVRL-GED-----NINVV---------E-GNEQFISASKSIVHPSYN 77
5CHA.pdb 54 ------V-T-TSDVVVA-GEF-----DQGSS---------S-EKIQKLKIAKVFKNSKYN 89
1PPB.pdb 84 PPWDKNFTE-NDLLVRI-GKH-----SRTRY---------ERNIEKISMLEKIYIHPRYN 127
1SGT.pdb 45 --------N-TSITATG-GVV-----DL--Q---------S-GAAVKVRSTKVLQAPGYN 77
1ARB.pdb 66 --------A-ASIVVYW-NYQNSTCRAPNTPASGANGDGSM-S--QTQSGSTVKA-T--Y 109
2SGA.pdb 37 ----------ISASWS------------------------------IGTRTGTSF----- 51
3SGB.pdb 37 ----------GATTWWA-NS------A-------------R-T-TVLGTTSGSSF----- 59
2ALP.pdb 40 ----------VNATARI-GG------------------------AVVGTFAARVF----- 59
2SNV.pdb 31 ------------GTIDHP--------V-------------L-------SKLKFTK----- 45
3EST.pdb 85 -T------DDVAA-GYDIALLRLAQ-SVTLNS--Y---VQLGV--LPRAGT---ILA-NN 124
2PKA.pdb 79 LS---ADGKDY---SHDLMLLRLQS-PAKITD--A---VKVLE--LPT--Q---EPE-LG 118
1TON.pdb 77 -PLIP--VHDH---SNDLMLLHLSE-PADITG--G---VKVID--LPT--K---EPK-VG 116
3RP2.pdb 83 -S------VPN---LHDIMLLKLEK-KVELTP--A---VNVVP--LPSPSD---FIH-PG 120
4PTP.pdb 78 -S------NTL---NNDIMLIKLKS-AASLNS--R---VASIS--LPT--S---CAS-AG 113
5CHA.pdb 90 -S------LTI---NNDITLLKLST-AASFSQ--T---VSAVC--LPSASD---DFA-AG 127
1PPB.pdb 128 -W-----RENL---DRDIALMKLKK-PVAFSD--Y---IHPVC--LPDRETAASLLQ-AG 169
1SGT.pdb 78 -G--------T---GKDWALIKLAQ-PINQ---------PTLK--IAT--T---TAY-NQ 107
1ARB.pdb 110 ----------A---TSDFTLLELNN-AANPA-F-N---LFWAG--WD-------RRDQNY 141
2SGA.pdb 52 ----------P---NNDYGIIRHSN-PAAADGRVYLYNGSYQDITTA---G---NAF-VG 90
3SGB.pdb 60 ----------P---NNDYGIVRYTNTTIPKDGTVG-----GQDITSA---A---NAT-VG 94
2ALP.pdb 60 ----------P---GNDRAWVSLTS-AQTLLPRVAN-GSSFVTVRGS---T---EAA-VG 97
2SNV.pdb 46 ----------S--SAYDMEFAQLPV-NM---R--S----EAFT--YT---S---EHP-EG 74
D
3EST.pdb 125 SPCYITGWGLTRTN-----G-QLAQTLQQAYLPT--VDYAIC-----S--SSSYWGSTV- 168
2PKA.pdb 119 STCEASGWGSIEPGPDD--F-EFPDEIQCVQLTL--LQNTFC-----A--DA--HPDKV- 163
1TON.pdb 117 STCLASGWGSTNPS--E--M-VVSHDLQCVNIHL--LSNEKC-----IET-Y--KDNV-- 159
3RP2.pdb 121 AMCWAAGWGKTGVR-----D-PTSYTLREVELRI--MDEKAC-----V--DY--R--YYE 161
4PTP.pdb 114 TQCLISGWGNTKSS--G--T-SYPDVLKCLKAPI--LSDSSC-----K--SA--YPGQI- 156
5CHA.pdb 128 TTCVTTGWGLTRY-------ANTPDRLQQASLPL--LSNTNC-----K--KY--WGTKI- 168
1PPB.pdb 170 YKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPI--VERPVC-----K--DS--TRIRI- 217
1SGT.pdb 108 GTFTVAGWGANREG-----G-SQQRYLLKANVPF--VSDAAC-----R--SA--YGNELV 150
1ARB.pdb 142 PGAIAIHHPN-------------VAEKRISNSTSPTSFV---A----W---G--G--GA- 173
2SGA.pdb 91 QAVQRSGST---------------T--GLRSGSV--TGL---NATVNY--GS--S--GI- 121
3SGB.pdb 95 MAVTRRGST---------------T--GTHSGSV--TAL---NATVNY--GG--G--DV- 125
2ALP.pdb 98 AAVCRSGRT---------------T--GYQCGTI--TAK---NVTANY--AE--G---A- 127
2SNV.pdb 75 FYNW-H----------------------HGAVQY--SGG--------------------- 88
3EST.pdb 169 KNSMVCAG-G--D----GVRSGCQGDSGGPLHCLV--NGQYAVHGVTSFVSRLG-C---- 214
2PKA.pdb 164 TESMLCAG-YL-P----GGKDTCMGDSGGPLICN------GMWQGITSWGH--TPC---- 205
1TON.pdb 160 TDVMLCAG-EM-E----GGKDTCAGDSGGPLICD------GVLQGITSGGA--TPC---- 201
3RP2.pdb 162 YKFQVCVG-SP-T----TLRAAFMGDSGGPLLCA------GVAHGIVSYGH--P-D---- 202
4PTP.pdb 157 TSNMFCAG-YL-E----GGKDSCQGDSGGPVVCS------GKLQGIVSWGS--G-C---- 197
5CHA.pdb 169 KDAMICAG-A-------SGVSSCMGDSGGPLVCKK--NGAWTLVGIVSWGS--S-T---- 211
1PPB.pdb 218 TDNMFCAG-YK-P-DEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE--G-C---- 267
1SGT.pdb 151 ANEEICAG-YPDT----GGVDTCQGDSGGPMFRKD-NADEWIQVGIVSWGY--G-C---- 197
1ARB.pdb 174 GTTHLNVQWQ---P---SGGVTEPGSSGSPIYSPE-----KRVLGQLHGGP--S------ 214
2SGA.pdb 122 VYGMIQTN-----------VCAQPGDSGGSLFAG------STALGLTSGGS--G-N---- 157
3SGB.pdb 126 VYGMIRTN-----------VCAEPGDSGGPLYSG------TRAIGLTSGGS--G-N---- 161
2ALP.pdb 128 VRGLTQGN-----------ACMGRGDSGGSWITSA-----GQAQGVMSGGN--V-QSNGN 168
2SNV.pdb 89 ---RFTIP----------RGVGGRGDSGRPIMDNS-----GRVVAIVLGGA--D------ 122
GdSG g g
3EST.pdb 215 -N---VT-RKPTVFTRVSAYIS--W--------INNVIASN------------------- 240
2PKA.pdb 206 -G---SA-NKPSIYTKLIFYLD--W--------IDDTITEN------------------P 232
1TON.pdb 202 -A---KP-KTPAIYAKLIKFTS--W--------IKKVMKEN------------------P 228
3RP2.pdb 203 ------A-KPPAIFTRVSTYVP--W--------INAVIN--------------------- 224
4PTP.pdb 198 -A---QK-NKPGVYTKVCNYVS--W--------IKQTIASN------------------- 223
5CHA.pdb 212 -C---ST-STPGVYARVTALVN--W--------VQQTLAAN------------------- 237
1PPB.pdb 268 -D---RD-GKYGFYTHVFRLKK--W--------IQKVIDQF------------------G 294
1SGT.pdb 198 -A---RP-GYPGVYTEVSTFAS--A--------IASAARTL------------------- 223
1ARB.pdb 215 SCSA-TGTNRSDQYGRVFTSWT--GGGAAASRL-SDWLDPASTGAQFIDG-LDS------ 263
2SGA.pdb 158 -CR---T-GGTTFYQPVTEALS--A--------YG-------ATV-----L--------- 181
3SGB.pdb 162 -CS---S-GGTTFFQPVTEALV--A--------YG-------VSV-----Y--------- 185
2ALP.pdb 169 NCGIPAS-QRSSLFERLQPILS--Q--------YG-------LSL-----V-T-----G- 198
2SNV.pdb 123 -----EGTRTALSVVTWN---SKGK--------TI-------KTT-----PEG-TEEW-- 151
3EST.pdb -
2PKA.pdb -
1TON.pdb -
3RP2.pdb -
4PTP.pdb -
5CHA.pdb -
1PPB.pdb 295 E 295
1SGT.pdb -
1ARB.pdb -
2SGA.pdb -
3SGB.pdb -
2ALP.pdb -
2SNV.pdb -
#=========================================ALIGNMENT END=============================================
#LEGEND:
#
# Colours indicate the chemical nature of the amino acid;
# Red = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W}
# Blue = Acidic,{D,E}
# Magenta = Basic,{K,R} and
# Green = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}.
#
# The "markup row" below each stretch of the multiple alignment is used to mark completely conserved
# residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment.
#
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