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# Program: MUSTANG-Lite v0.1: A  Multiple structural alignment algorithm
# Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey
# Rundate: Fri Jul 22 23:42:00 2005
# Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/HOMSTRAD_Datasets/results/Topoisomerase_I_core.html
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#====================================
# Aligned_structures: 2
#   1: 1a31a.pdb
#   2: 1a41.pdb
#
# Length:        273
# Identity:       33/273 ( 12.1%)  (Calculated as the percentage of conserved columns in the alignment.)
# Similarity:     33/273 ( 12.1%)  (Calculated as the percentage of semi-conserved columns in the alignment)
# Gaps:           84/273 ( 30.8%)  (Calculated as the percentage of columns with atleast one gap.)

#===========================================ALIGNMENT START=========================================


1a31a.pdb               1  PSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKS--KEMKVRQRAVALYFIDKLALR   58
1a41.pdb                1  --NAKRD-------RIFVRVYNVMKRINCFINKNIKKSST-DSNYQLAVFMLMETMF---   47
                                             R       I        K         Q AV           

1a31a.pdb              59  AGNEKEEGETADTV-------GCCSLRVEHINLHPELDGQEYVVEFDFLGKD-SIRYYNK  110
1a41.pdb               48  --------------FKENETVGLLTLKNKHIEISPD----EIVIKFVGK---DKVSHEFV   86
                                                G   L   HI   P     E V  F              

1a31a.pdb             111  VPVE-KRVFKNLQLFMENK--QPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASIT  167
1a41.pdb               87  VH-KSNRLYKPLLKLTD--DSSPEEFLFNKLSERKVYECIKQFG--IRIKDLRTYGVNYT  141
                           V     R  K L          PE  LF  L                  K  RTY    T

1a31a.pdb             168  LQQQLKELTA---PDE-NIPAKILSYNRANRAVKLNL--------DPRITVAWCKKWGV-  214
1a41.pdb              142  FLYNFWTNVKSISPLPSPKKLIALTIKQTAEVV----GHTPSISKRAYMATTILEMVK-D  196
                                        P         L        V                           

1a31a.pdb             215  -PIEKIYNKT---QREKFAWAIDMADEDYEF--  241
1a41.pdb              197  KNFLDVVS--KTTFDEFLSIVVDHV------KS  221
                                          E      D          


#=========================================ALIGNMENT END=============================================
#LEGEND:
#
# Colours indicate the chemical nature of the amino acid;
# Red         = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W}
# Blue        = Acidic,{D,E}
# Magenta     = Basic,{K,R} and
# Green       = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}.
#
# The "markup row" below each stretch of the multiple alignment is used to mark completely conserved
# residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment.
#
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