3e7o:A (ASN90) to (ASP169) CRYSTAL STRUCTURE OF JNK2 | MAP KINASE INSERT, ACTIVATION LOOP, INDAZOLE INHIBITOR, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3e7o:B (ASN90) to (ASP169) CRYSTAL STRUCTURE OF JNK2 | MAP KINASE INSERT, ACTIVATION LOOP, INDAZOLE INHIBITOR, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
2aly:B (GLU566) to (GLU645) CRYSTAL STRUCTURE OF T.THERMOPHILUS PHENYLALANYL-TRNA SYNTHETASE COMPLEXED WITH 5'-O-[N-(L-TYROSYL)SULPHAMOYL]ADENOSINE | PROTEIN-LIGAND COMPLEX, LIGASE
1ndd:B (MET101) to (VAL170) STRUCTURE OF NEDD8 | NEDD8, NEDD-8, UBIQUITIN-LIKE, PROTEOLYSIS, SIGNALING PROTEIN
3rny:B (LYS433) to (GLU490) CRYSTAL STRUCTURE OF HUMAN RSK1 C-TERMINAL KINASE DOMAIN | PROTEIN KINASE, AUTOINHIBITION, TRANSFERASE
2aq3:D (GLN127) to (ASP197) CRYSTAL STRUCTURE OF T-CELL RECEPTOR V BETA DOMAIN VARIANT COMPLEXED WITH SUPERANTIGEN SEC3 | T-CELL RECEPTOR V BETA DOMAIN,STAPHLOCOCCAL ENTEROTOXIN C3, COMPLEX STRUCTURE, IMMUNE SYSTEM
3rps:A (SER51) to (GLU114) STRUCTURE OF HUMAN CK2ALPHA IN COMPLEX WITH THE ATP-COMPETITIVE INHIBITOR 3-(4,5,6,7-TETRABROMO-1H-BENZOTRIAZOL-1-YL)PROPAN-1-OL | EUKARYOTIC PROTEIN KINASE FOLD, ATP CK2BETA, PHOSPHORYLATION, CYTOPLASM NUCLEUS, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2oic:B (GLY198) to (VAL263) CRYSTAL STRUCTURE OF IRAK4 KINASE DOMAIN COMPLEXED WITH STAUROSPORINE | KINASE, TRANSFERASE
2oic:D (GLY198) to (VAL263) CRYSTAL STRUCTURE OF IRAK4 KINASE DOMAIN COMPLEXED WITH STAUROSPORINE | KINASE, TRANSFERASE
4gyg:A (SER108) to (MET189) CRYSTAL STRUCTURE OF THE RIO2 KINASE FROM CHAETOMIUM THERMOPHILUM | RIO-TYPE SER/THR PROTEIN KINASE, RIBOSOME BIOGENESIS FACTOR, PRE-40S MATURATION, RIBOSOMAL RNA PROCESSING, PRE-40S, RIBOSOMAL RNA, PHOSPHORYLATION, TRANSFERASE
3eee:A (ALA115) to (LYS179) PROBING THE FUNCTION OF HEME DISTORTION IN THE H-NOX FAMILY | HEMOPROTEIN, SIGNALING PROTEIN
3eee:B (ALA115) to (LYS179) PROBING THE FUNCTION OF HEME DISTORTION IN THE H-NOX FAMILY | HEMOPROTEIN, SIGNALING PROTEIN
3eee:C (ALA112) to (LYS179) PROBING THE FUNCTION OF HEME DISTORTION IN THE H-NOX FAMILY | HEMOPROTEIN, SIGNALING PROTEIN
3eee:D (ALA115) to (LYS179) PROBING THE FUNCTION OF HEME DISTORTION IN THE H-NOX FAMILY | HEMOPROTEIN, SIGNALING PROTEIN
3eh8:A (ASP16) to (ASP73) CRYSTAL STRUCTURE OF Y2 I-ANII VARIANT (F13Y/S111Y)/DNA COMPLEX WITH CALCIUM | PROTEIN-DNA COMPLEX, ENDONUCLEASE, HYDROLASE, INTRON HOMING, MITOCHONDRION, MRNA PROCESSING, MRNA SPLICING, NUCLEASE, HYDROLASE- DNA COMPLEX
3eh8:A (GLU148) to (THR204) CRYSTAL STRUCTURE OF Y2 I-ANII VARIANT (F13Y/S111Y)/DNA COMPLEX WITH CALCIUM | PROTEIN-DNA COMPLEX, ENDONUCLEASE, HYDROLASE, INTRON HOMING, MITOCHONDRION, MRNA PROCESSING, MRNA SPLICING, NUCLEASE, HYDROLASE- DNA COMPLEX
3eh8:D (ASP16) to (ASP73) CRYSTAL STRUCTURE OF Y2 I-ANII VARIANT (F13Y/S111Y)/DNA COMPLEX WITH CALCIUM | PROTEIN-DNA COMPLEX, ENDONUCLEASE, HYDROLASE, INTRON HOMING, MITOCHONDRION, MRNA PROCESSING, MRNA SPLICING, NUCLEASE, HYDROLASE- DNA COMPLEX
3eh8:D (GLU148) to (THR204) CRYSTAL STRUCTURE OF Y2 I-ANII VARIANT (F13Y/S111Y)/DNA COMPLEX WITH CALCIUM | PROTEIN-DNA COMPLEX, ENDONUCLEASE, HYDROLASE, INTRON HOMING, MITOCHONDRION, MRNA PROCESSING, MRNA SPLICING, NUCLEASE, HYDROLASE- DNA COMPLEX
3eh8:G (ASP16) to (ASP73) CRYSTAL STRUCTURE OF Y2 I-ANII VARIANT (F13Y/S111Y)/DNA COMPLEX WITH CALCIUM | PROTEIN-DNA COMPLEX, ENDONUCLEASE, HYDROLASE, INTRON HOMING, MITOCHONDRION, MRNA PROCESSING, MRNA SPLICING, NUCLEASE, HYDROLASE- DNA COMPLEX
3eh8:G (GLU148) to (THR204) CRYSTAL STRUCTURE OF Y2 I-ANII VARIANT (F13Y/S111Y)/DNA COMPLEX WITH CALCIUM | PROTEIN-DNA COMPLEX, ENDONUCLEASE, HYDROLASE, INTRON HOMING, MITOCHONDRION, MRNA PROCESSING, MRNA SPLICING, NUCLEASE, HYDROLASE- DNA COMPLEX
3ehf:A (THR302) to (PRO366) CRYSTAL STRUCTURE OF DESKC IN COMPLEX WITH AMP-PCP | FOUR-HELIX BUNDLE, GHL ATPASE DOMAIN, KINASE, TRANSFERASE
3ehf:D (THR302) to (PRO366) CRYSTAL STRUCTURE OF DESKC IN COMPLEX WITH AMP-PCP | FOUR-HELIX BUNDLE, GHL ATPASE DOMAIN, KINASE, TRANSFERASE
3ehj:B (THR302) to (PRO366) CRYSTAL STRUCTURE OF DESKC-H188V IN COMPLEX WITH AMP-PCP | FOUR-HELIX BUNDLE, GHL ATPASE DOMAIN, KINASE, TRANSFERASE
3ehh:A (LYS301) to (PRO366) CRYSTAL STRUCTURE OF DESKC-H188V IN COMPLEX WITH ADP | FOUR-HELIX BUNDLE, GHL ATPASE DOMAIN, KINASE, TRANSFERASE
3ehh:B (THR302) to (PRO366) CRYSTAL STRUCTURE OF DESKC-H188V IN COMPLEX WITH ADP | FOUR-HELIX BUNDLE, GHL ATPASE DOMAIN, KINASE, TRANSFERASE
2oo8:X (GLY836) to (GLU903) SYNTHESIS, STRUCTURAL ANALYSIS, AND SAR STUDIES OF TRIAZINE DERIVATIVES AS POTENT, SELECTIVE TIE-2 INHIBITORS | KINASE, TRANSFERASE
3rv6:A (VAL254) to (ALA341) STRUCTURE OF A M. TUBERCULOSIS SALICYLATE SYNTHASE, MBTI, IN COMPLEX WITH AN INHIBITOR WITH PHENYL R-GROUP | STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, SALICYLATE SYNTHASE, CHORISMATE BINDING, ISOMERASE-ISOMERASE INHIBITOR COMPLEX
3rv6:B (GLU252) to (PRO345) STRUCTURE OF A M. TUBERCULOSIS SALICYLATE SYNTHASE, MBTI, IN COMPLEX WITH AN INHIBITOR WITH PHENYL R-GROUP | STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, SALICYLATE SYNTHASE, CHORISMATE BINDING, ISOMERASE-ISOMERASE INHIBITOR COMPLEX
3rv8:A (VAL254) to (ASP344) STRUCTURE OF A M. TUBERCULOSIS SALICYLATE SYNTHASE, MBTI, IN COMPLEX WITH AN INHIBITOR WITH CYCLOPROPYL R-GROUP | STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, SALICYLATE SYNTHASE, CHORISMATE BINDING, ISOMERASE-ISOMERASE INHIBITOR COMPLEX
3rv8:D (PRO251) to (ASP344) STRUCTURE OF A M. TUBERCULOSIS SALICYLATE SYNTHASE, MBTI, IN COMPLEX WITH AN INHIBITOR WITH CYCLOPROPYL R-GROUP | STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, SALICYLATE SYNTHASE, CHORISMATE BINDING, ISOMERASE-ISOMERASE INHIBITOR COMPLEX
3rv9:A (VAL254) to (PRO345) STRUCTURE OF A M. TUBERCULOSIS SALICYLATE SYNTHASE, MBTI, IN COMPLEX WITH AN INHIBITOR WITH ETHYL R-GROUP | STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, CHORISMATE BINDING, ISOMERASE-ISOMERASE INHIBITOR COMPLEX
4wo5:B (GLY469) to (GLN530) CRYSTAL STRUCTURE OF A BRAF KINASE DOMAIN MONOMER | KINASE, MONOMER, INHIBITOR, COMPLEX, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2b1p:A (ASN128) to (ASP207) INHIBITOR COMPLEX OF JNK3 | ENZYME-INHIBITOR COMPLEX, KINASE INHIBITOR, TRANSFERASE
2osc:A (GLN837) to (GLU903) SYNTHESIS, STRUCTURAL ANALYSIS, AND SAR STUDIES OF TRIAZINE DERIVATIVES AS POTENT, SELECTIVE TIE-2 INHIBITORS | KINASE DOMAIN TIE-2, TRANSFERASE
2oso:A (GLY81) to (LYS155) CRYSTAL STRUCTURE OF A VINYL-4-REDUCTASE FAMILY PROTEIN (MJ_1460) FROM METHANOCALDOCOCCUS JANNASCHII DSM AT 1.90 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, METAL BINDING PROTEIN
4h58:B (MET516) to (ASP593) BRAF IN COMPLEX WITH COMPOUND 3 | PROTEIN KINASE, STRUCTURE BASED DRUG DISCOVERY, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
2ow7:A (ASP956) to (ALA1038) GOLGI ALPHA-MANNOSIDASE II COMPLEX WITH (1R,6S,7R,8S)-1- THIONIABICYCLO[4.3.0]NONAN-7,8-DIOL CHLORIDE | GLYCOSYL HYDROLASE FAMILY 38, HYDROLASE
4wrs:A (GLY50) to (ILE119) CRYSTAL STRUCTURE OF HUMAN PIM-1 KINASE IN COMPLEX WITH AN AZASPIRO PYRAZINYL-INDAZOLE INHIBITOR. | TRANSFERASE, SERINE/THREONINE PROTEIN KINASE
4wsb:C (ILE686) to (LYS738) BAT INFLUENZA A POLYMERASE WITH BOUND VRNA PROMOTER | TRANSFERASE-RNA COMPLEX
2ozo:A (GLY403) to (ILE477) AUTOINHIBITED INTACT HUMAN ZAP-70 | INACTIVE ZAP-70, TANDEM SH2, AUTOINHIBITION, ITAM, HYDROGEN BONDING NETWORK, TCR SIGNALING, TRANSFERASE
1b1z:A (LYS115) to (PHE184) STREPTOCOCCAL PYROGENIC EXOTOXIN A1 | SUPERANTIGEN, ZINC BINDING, PYROGENIC EXOTOXIN
2p2i:B (GLN847) to (GLU917) CRYSTAL STRUCTURE OF THE VEGFR2 KINASE DOMAIN IN COMPLEX WITH A NICOTINAMIDE INHIBITOR | RECEPTOR TYROSINE KINASE, KDR, TRANSFERASE
1b24:A (ASP21) to (SER84) I-DMOI, INTRON-ENCODED ENDONUCLEASE | INTRON-ENCODED, ENDONUCLEASE, HOMING, THERMOSTABLE
2p4i:B (GLN837) to (GLU903) EVOLUTION OF A HIGHLY SELECTIVE AND POTENT 2-(PYRIDIN-2-YL)- 1,3,5-TRIAZINE TIE-2 KINASE INHIBITOR | TIE-2 KINASE INHIBITOR TRIAZINE, TRANSFERASE
1b4a:A (ILE85) to (ILE131) STRUCTURE OF THE ARGININE REPRESSOR FROM BACILLUS STEAROTHERMOPHILUS | REPRESSOR, ARGININE, HELIX TURN HELIX
1b4a:B (ILE85) to (ILE131) STRUCTURE OF THE ARGININE REPRESSOR FROM BACILLUS STEAROTHERMOPHILUS | REPRESSOR, ARGININE, HELIX TURN HELIX
1b4a:C (ILE85) to (ILE131) STRUCTURE OF THE ARGININE REPRESSOR FROM BACILLUS STEAROTHERMOPHILUS | REPRESSOR, ARGININE, HELIX TURN HELIX
1b4a:D (ILE85) to (ILE131) STRUCTURE OF THE ARGININE REPRESSOR FROM BACILLUS STEAROTHERMOPHILUS | REPRESSOR, ARGININE, HELIX TURN HELIX
1b4a:E (ILE85) to (ILE131) STRUCTURE OF THE ARGININE REPRESSOR FROM BACILLUS STEAROTHERMOPHILUS | REPRESSOR, ARGININE, HELIX TURN HELIX
1b4a:F (ILE85) to (ILE131) STRUCTURE OF THE ARGININE REPRESSOR FROM BACILLUS STEAROTHERMOPHILUS | REPRESSOR, ARGININE, HELIX TURN HELIX
2p5m:B (ILE87) to (ILE131) C-TERMINAL DOMAIN HEXAMER OF AHRC BOUND WITH L-ARGININE | ALPHA-BETA, L-ARGININE BINDING DOMAIN, DNA BINDING PROTEIN
2p9k:D (ASP149) to (PRO229) CRYSTAL STRUCTURE OF BOVINE ARP2/3 COMPLEX CO-CRYSTALLIZED WITH ATP AND CROSSLINKED WITH GLUTARALDEHYDE | COMPLEX, ACTIN, WD REPEAT, STRUCTURAL PROTEIN
2p9i:D (THR151) to (PRO229) CRYSTAL STRUCTURE OF BOVINE ARP2/3 COMPLEX CO-CRYSTALLIZED WITH ADP AND CROSSLINKED WITH GLUTERALDEHYDE | COMPLEX, WD REPEAT, ACTIN, STRUCTURAL PROTEIN
2bh2:A (HIS188) to (VAL242) CRYSTAL STRUCTURE OF E. COLI 5-METHYLURIDINE METHYLTRANSFERASE RUMA IN COMPLEX WITH RIBOSOMAL RNA SUBSTRATE AND S-ADENOSYLHOMOCYSTEINE. | IRON-SULFUR CLUSTER, METHYLTRANSFERASE, RNA MODIFICATION, RNA PROCESSING, TRANSFERASE, RUMA, BASE FLIPPING, SAM, OB- FOLD, PROTEIN-RNA COMPLEX, BASE STACKING, SUBSTRATE SELECTIVITY, GENERAL BASE, PRODUCT RELEASE, 4FE-4S, DIRECT PROTEIN SEQUENCING, METAL-BINDING
2p9l:D (ASP149) to (PRO229) CRYSTAL STRUCTURE OF BOVINE ARP2/3 COMPLEX | ACTIN, WD REPEAT, COMPLEX, STRUCTURAL PROTEIN
2p9n:D (ASP149) to (PHE228) CRYSTAL STRUCTURE OF BOVINE ARP2/3 COMPLEX CO-CRYSTALLIZED WITH ADP | ACTIN, WD REPEAT, COMPLEX, STRUCTURAL PROTEIN
2p9s:D (ASP149) to (PRO229) STRUCTURE OF BOVINE ARP2/3 COMPLEX CO-CRYSTALLIZED WITH ATP/MG2+ | ACTIN, WD REPEAT, COMPLEX, STRUCTURAL PROTEIN
2p9u:D (ASP149) to (PRO229) CRYSTAL STRUCTURE OF BOVINE ARP2/3 COMPLEX CO-CRYSTALLIZED WITH AMP-PNP AND CALCIUM | ACTIN, WD REPEAT, COMPLEX, STRUCTURAL PROTEIN
1bgw:A (ARG884) to (SER949) TOPOISOMERASE RESIDUES 410-1202, | ISOMERASE, TOPOISOMERASE, DNA-BINDING, PHOSPHORYLATED NUCLEAR PROTEIN, DNA-BINDING PROTEIN
2brn:A (GLU22) to (PHE83) STRUCTURE-BASED DESIGN OF NOVEL CHK1 INHIBITORS: INSIGHTS INTO HYDROGEN BONDING AND PROTEIN-LIGAND AFFINITY | DRUG DESIGN, FURANOPYRIMIDINE, MOLECULAR RECOGNITION, ONCOLOGY, PYRROLOPYRIMIDINE, ATP-BINDING, CELL CYCLE, DNA DAMAGE, KINASE, NUCLEAR PROTEIN, PHOSPHORYLATION, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
1oao:C (LYS365) to (SER431) NIZN[FE4S4] AND NINI[FE4S4] CLUSTERS IN CLOSED AND OPEN ALPHA SUBUNITS OF ACETYL-COA SYNTHASE/CARBON MONOXIDE DEHYDROGENASE | OXIDOREDUCTASE-TRANSFERASE COMPLEX, ELECTRON TRANSFER, OXIDOREDUCTASE, ACETYL-COA FORMATION, WOOD/LJUNGDAHL PATHWAY, NICKEL
1oao:D (LYS365) to (SER431) NIZN[FE4S4] AND NINI[FE4S4] CLUSTERS IN CLOSED AND OPEN ALPHA SUBUNITS OF ACETYL-COA SYNTHASE/CARBON MONOXIDE DEHYDROGENASE | OXIDOREDUCTASE-TRANSFERASE COMPLEX, ELECTRON TRANSFER, OXIDOREDUCTASE, ACETYL-COA FORMATION, WOOD/LJUNGDAHL PATHWAY, NICKEL
3fcc:A (ALA384) to (GLU449) CRYSTAL STRUCTURE OF DLTA PROTEIN IN COMPLEX WITH ATP AND MAGNESIUM | DLTA, AMP-FORMING DOMAIN, D-ALANINE, ADENYLATION, D-ALANINE CARRIER PROTEIN LIGASE, ATP COMPLEX, LIGASE
3ffh:B (LYS294) to (THR342) THE CRYSTAL STRUCTURE OF HISTIDINOL-PHOSPHATE AMINOTRANSFERASE FROM LISTERIA INNOCUA CLIP11262. | APC88260, HISTIDINOL-PHOSPHATE AMINOTRANSFERASE, LISTERIA INNOCUA CLIP11262, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, AMINO-ACID BIOSYNTHESIS, AMINOTRANSFERASE, HISTIDINE BIOSYNTHESIS, PYRIDOXAL PHOSPHATE, TRANSFERASE
4hyi:A (GLY21) to (PHE83) X-RAY CRYSTAL STRUCTURE OF COMPOUND 40 BOUND TO HUMAN CHK1 KINASE DOMAIN | SERINE/THREONINE-PROTEIN KINASE CHK1 INHIBITOR, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
2byl:B (THR369) to (ALA415) STRUCTURE OF ORNITHINE AMINOTRANSFERASE TRIPLE MUTANT Y85I Y55A G320F | TRANSFERASE, DISEASE MUTATION, MITOCHONDRION, TRANSIT PEPTIDE PLP-DEPENDENT ENZYME, POLYMORPHISM, PYRIDOXAL PHOSPHATE
2byl:C (THR369) to (ALA415) STRUCTURE OF ORNITHINE AMINOTRANSFERASE TRIPLE MUTANT Y85I Y55A G320F | TRANSFERASE, DISEASE MUTATION, MITOCHONDRION, TRANSIT PEPTIDE PLP-DEPENDENT ENZYME, POLYMORPHISM, PYRIDOXAL PHOSPHATE
2bzh:B (GLY50) to (ILE119) CRYSTAL STRUCTURE OF THE HUMAN PIM1 IN COMPLEX WITH A RUTHENIUM ORGANOMETALLIC LIGAND RU1 | PIM1, KINASE, CANCER, LEUKEMIA, NUCLEAR PROTEIN, NUCLEOTIDE-BINDING, TRANSFERASE
2bzi:B (GLY50) to (ILE119) CRYSTAL STRUCTURE OF THE HUMAN PIM1 IN COMPLEX WITH A RUTHENIUM ORGANOMETALLIC LIGAND RU2 | PIM1, KINASE, CANCER, LEUKEMIA, NUCLEAR PROTEIN, NUCLEOTIDE-BINDING, TRANSFERASE
2bzj:A (GLY50) to (ILE119) CRYSTAL STRUCTURE OF THE HUMAN PIM1 IN COMPLEX WITH A RUTHENIUM ORGANOMETALLIC LIGAND RU3 | PIM1, KINASE, CANCER, LEUKEMIA, NUCLEAR PROTEIN, NUCLEOTIDE- BINDING, TRANSFERASE
2c0j:B (SER84) to (PRO157) CRYSTAL STRUCTURE OF THE BET3-TRS33 HETERODIMER | TRANSPORT, TRANSPORT PROTEIN, ENDOPLASMIC RETICULUM, ER-GOLGI TRANSPORT, LIPOPROTEIN, PALMITATE
3fhz:A (SER107) to (VAL152) CRYSTAL STRUCTURE OF THE ARGININE REPRESSOR FROM MYCOBACTERIUM TUBERCULOSIS BOUND WITH ITS DNA OPERATOR AND CO-REPRESSOR, L-ARGININE | MYCOBACTERIUM TUBERCULOSIS, ARGININE REPRESSOR PROTEIN, DNA BINDING, ARGR-OPERATOR TERNARY COMPLEX, STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, AMINO-ACID BIOSYNTHESIS, ARGININE BIOSYNTHESIS, DNA-BINDING, REPRESSOR, TRANSCRIPTION, TRANSCRIPTION REGULATION, DNA BINDING PROTEIN-DNA COMPLEX
3fhz:E (SER107) to (VAL152) CRYSTAL STRUCTURE OF THE ARGININE REPRESSOR FROM MYCOBACTERIUM TUBERCULOSIS BOUND WITH ITS DNA OPERATOR AND CO-REPRESSOR, L-ARGININE | MYCOBACTERIUM TUBERCULOSIS, ARGININE REPRESSOR PROTEIN, DNA BINDING, ARGR-OPERATOR TERNARY COMPLEX, STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, AMINO-ACID BIOSYNTHESIS, ARGININE BIOSYNTHESIS, DNA-BINDING, REPRESSOR, TRANSCRIPTION, TRANSCRIPTION REGULATION, DNA BINDING PROTEIN-DNA COMPLEX
3fhz:F (SER107) to (VAL152) CRYSTAL STRUCTURE OF THE ARGININE REPRESSOR FROM MYCOBACTERIUM TUBERCULOSIS BOUND WITH ITS DNA OPERATOR AND CO-REPRESSOR, L-ARGININE | MYCOBACTERIUM TUBERCULOSIS, ARGININE REPRESSOR PROTEIN, DNA BINDING, ARGR-OPERATOR TERNARY COMPLEX, STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, AMINO-ACID BIOSYNTHESIS, ARGININE BIOSYNTHESIS, DNA-BINDING, REPRESSOR, TRANSCRIPTION, TRANSCRIPTION REGULATION, DNA BINDING PROTEIN-DNA COMPLEX
4xhk:B (GLY50) to (ILE119) PIM1 KINASE IN COMPLEX WITH COMPOUND 1S | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3fjp:A (GLY26) to (ASN123) APO STRUCTURE OF BIOTIN PROTEIN LIGASE FROM AQUIFEX AEOLICUS | BPL, BIOTIN PROTEIN LIGASE, LIGASE
2c3j:A (GLY21) to (PHE83) IDENTIFICATION OF A BURIED POCKET FOR POTENT AND SELECTIVE INHIBITION OF CHK1: PREDICTION AND VERIFICATION | DRUG DESIGN, MOLECULAR MODELING, MOLECULAR RECOGNITION, ONCOLOGY, TRANSFERASE, CELL CYCLE, DNA DAMAGE, DNA REPAIR, ATP-BINDING, KINASE, NUCLEAR PROTEIN, NUCLEOTIDE-BINDING, PHOSPHORYLATION, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, UBL CONJUGATION
4xj6:A (GLN104) to (ILE183) CRYSTAL STRUCTURE OF ESCHERICHIA COLI DNCV 3'-DEOXY GTP BOUND FORM | CYCLIC GMP-AMP SYNTHASE, BACTERIAL VIRULENCE, NUCLEOTIDYLTRANSFERASE
3sj5:B (GLY111) to (LYS179) I5F MUTANT STRUCTURE OF T. TENGCONGENSIS H-NOX | NO OR O2-SENSING PROTEIN, SIGNALING PROTEIN
3skc:A (THR470) to (GLN530) HUMAN B-RAF KINASE IN COMPLEX WITH AN AMIDE LINKED PYRAZOLOPYRIDINE INHIBITOR | KINASE, ATP-COMPETITIVE INHIBITOR, TRANSFERASE, RAS, MEK, C-RAF, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3skc:B (LYS473) to (GLN530) HUMAN B-RAF KINASE IN COMPLEX WITH AN AMIDE LINKED PYRAZOLOPYRIDINE INHIBITOR | KINASE, ATP-COMPETITIVE INHIBITOR, TRANSFERASE, RAS, MEK, C-RAF, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3fly:A (SER37) to (HIS107) P38 KINASE CRYSTAL STRUCTURE IN COMPLEX WITH 6-(2,4- DIFLUORO-PHENOXY)-2-ISOPROPYLAMINO-8-METHYL-8H-PYRIDO[2,3- D]PYRIMIDIN-7-ONE | P38; MAP KINASE; SERINE/THREONINE KINASE, ALTERNATIVE SPLICING, ATP-BINDING, CYTOPLASM, KINASE, NUCLEOTIDE- BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, SIGNALING PROTEIN
3flz:A (SER37) to (HIS107) P38 KINASE CRYSTAL STRUCTURE IN COMPLEX WITH 8-METHYL-6-PHENOXY-2- (TETRAHYDRO-PYRAN-4-YLAMINO)-8H-PYRIDO[2,3-D]PYRIMIDIN-7-ONE | P38; MAP KINASE; SERINE/THREONINE KINASE, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, SERINE/THREONINE- PROTEIN KINASE, TRANSFERASE, SIGNALING PROTEIN
3fn5:A (ILE95) to (GLY146) CRYSTAL STRUCTURE OF SORTASE A (SPY1154) FROM STREPTOCOCCUS PYOGENES SEROTYPE M1 STRAIN SF370 | SORTASE-FOLD, HYDROLASE
4i5v:B (GLU86) to (LYS170) CRYSTAL STRUCTURE OF YEAST AP4A PHOSPHORYLASE APA2 IN COMPLEX WITH AP4A | ALPHA/BETA FOLD, AP4A PHOSPHORYLASE, AP4A, TRANSFERASE
4i5w:B (GLU86) to (GLN166) CRYSTAL STRUCTURE OF YEAST AP4A PHOSPHORYLASE APA2 IN COMPLEX WITH AMP | ALPHA/BETA FOLD, AP4A PHOSPHORYLASE, AP4A, TRANSFERASE
2c6l:A (GLY16) to (GLU81) CRYSTAL STRUCTURE OF THE HUMAN CDK2 COMPLEXED WITH THE TRIAZOLOPYRIMIDINE INHIBITOR | TRANSFERASE, SERINE/THREONINE PROTEIN KINASE, CDK2, ATP-BINDING, CELL CYCLE, MITOSIS, PHOSPHORYLATION, TRIAZOLOPYRIMIDINE INHIBITOR, CELL DIVISION, KINASE, POLYMORPHISM, NUCLEOTIDE-BINDING
2q0n:A (GLY333) to (GLU396) STRUCTURE OF HUMAN P21 ACTIVATING KINASE 4 (PAK4) IN COMPLEX WITH A CONSENSUS PEPTIDE | PROTEIN KINASE, PHOSPHORYLATION, NUCLEOTIDE-BINDING, PAK4, STE20, KINASE, TRANSFERASE, ATP-BINDING, SERINE/THREONINE-PROTEIN KINASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC
4iae:A (GLN114) to (GLU182) CRYSTAL STRUCTURE OF BAY 60-2770 BOUND TO NOSTOC H-NOX DOMAIN | ACTIVATION, HNOX DOMAIN, HEME BINDING, NO BINDING, LYASE
4iae:B (ALA119) to (GLU182) CRYSTAL STRUCTURE OF BAY 60-2770 BOUND TO NOSTOC H-NOX DOMAIN | ACTIVATION, HNOX DOMAIN, HEME BINDING, NO BINDING, LYASE
4iah:A (GLN114) to (GLU182) CRYSTAL STRUCTURE OF BAY 60-2770 BOUND C139A H-NOX DOMAIN WITH S- NITROSYLATED CONSERVED C122 | H-NOX DOMAIN, SOLUBLE GUANYLYL CYCLASE, BAY 60-2770, S-NITROSYLATION, CONSERVED C122, HEME BINDING, NO BINDING, LYASE
4iam:A (ALA119) to (GLU182) CRYSTAL STRUCTURE OF THE C139A MUTANT OF NOSTOC H-NOX DOMAIN | HNOX DOMAIN, SOLUBLE GUANYLYL CYCLASE, C139A MUTANT, NOSTOC, HEME BINDING, NO BINDING, LYASE
4iam:B (GLN114) to (GLU182) CRYSTAL STRUCTURE OF THE C139A MUTANT OF NOSTOC H-NOX DOMAIN | HNOX DOMAIN, SOLUBLE GUANYLYL CYCLASE, C139A MUTANT, NOSTOC, HEME BINDING, NO BINDING, LYASE
3sqo:P (THR63) to (LYS125) PCSK9 J16 FAB COMPLEX | CHOLESTEROL REGULATION, LDLR, HYDROLASE-IMMUNE SYSTEM COMPLEX
2q3s:F (PRO7) to (THR80) ENSEMBLE REFINEMENT OF THE PROTEIN CRYSTAL STRUCTURE OF GENE PRODUCT FROM ARABIDOPSIS THALIANA AT5G06450 | ENSEMBLE REFINEMENT, REFINEMENT METHODOLOGY DEVELOPMENT, PROTEIN, HOMOHEXAMER, AT5G06450, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, CENTER FOR EUKARYOTIC STRUCTURAL GENOMICS, CESG, UNKNOWN FUNCTION
3fv8:A (ASN128) to (ASP207) JNK3 BOUND TO PIPERAZINE AMIDE INHIBITOR, SR2774. | JNK3, PROTEIN-INHIBITOR COMPLEX, ALTERNATIVE SPLICING, ATP- BINDING, CHROMOSOMAL REARRANGEMENT, CYTOPLASM, EPILEPSY, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3fwq:A (SER51) to (GLU114) INACTIVE CONFORMATION OF HUMAN PROTEIN KINASE CK2 CATALYTIC SUBUNIT | CASEIN KINASE 2, PROTEIN KINASE CK2, EUKARYOTIC PROTEIN KINASES, INACTIVE CONFORMATION, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, WNT SIGNALING PATHWAY
2q7e:A (LYS321) to (HIS392) THE STRUCTURE OF PYRROLYSYL-TRNA SYNTHETASE BOUND TO AN ATP ANALOGUE | AMINOACYL-TRNA SYNTHETASE, PYRROLYSINE, LIGASE
2q7g:A (LYS321) to (HIS392) PYRROLYSINE TRNA SYNTHETASE BOUND TO A PYRROLYSINE ANALOGUE (CYC) AND ATP | PYRROLYSYL-TRNA SYNTETHETASE, PYRROLYSINE, LIGASE
1d1r:A (ASP31) to (GLN86) NMR SOLUTION STRUCTURE OF THE PRODUCT OF THE E. COLI YCIH GENE. | ALPHA-BETA PLAIT, OPEN-FACED BETA SANDWICH, FERREDOXIN-LIKE FOLD, STRUCTURAL GENOMICS
1p4f:A (LYS29) to (GLU94) DEATH ASSOCIATED PROTEIN KINASE CATALYTIC DOMAIN WITH BOUND INHIBITOR FRAGMENT | TRANSFERASE, KINASE
3g15:A (LEU124) to (GLN207) CRYSTAL STRUCTURE OF HUMAN CHOLINE KINASE ALPHA IN COMPLEX WITH HEMICHOLINIUM-3 AND ADP | NON-PROTEIN KINASE, CHOLINE KINASE, STRUCTURAL GENOMICS CONSORTIUM, SGC, HEMICHOLINIUM-3, KINASE, TRANSFERASE
3g2f:B (GLY215) to (GLU280) CRYSTAL STRUCTURE OF THE KINASE DOMAIN OF BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE II (BMPR2) AT 2.35 A RESOLUTION | KINASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, ATP-BINDING, DISEASE MUTATION, GLYCOPROTEIN, MAGNESIUM, MANGANESE, MEMBRANE, METAL-BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, RECEPTOR, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, TRANSMEMBRANE
2cgu:A (TYR20) to (PHE83) IDENTIFICATION OF CHEMICALLY DIVERSE CHK1 INHIBITORS BY RECEPTOR-BASED VIRTUAL SCREENING | TRANSFERASE, DOCKING, DRUG DESIGN, ONCOLOGY, VIRTUAL SCREENING, ATP- BINDING, CELL CYCLE, DNA DAMAGE, DNA REPAIR, KINASE, NUCLEAR PROTEIN, NUCLEOTIDE-BINDING, PHOSPHORYLATION, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, UBL CONJUGATION
2cgv:A (TYR20) to (PHE83) IDENTIFICATION OF CHEMICALLY DIVERSE CHK1 INHIBITORS BY RECEPTOR-BASED VIRTUAL SCREENING | TRANSFERASE, DOCKING, DRUG DESIGN, ONCOLOGY, VIRTUAL SCREENING, ATP- BINDING, CELL CYCLE, DNA DAMAGE, DNA REPAIR, KINASE, NUCLEAR PROTEIN, NUCLEOTIDE-BINDING, PHOSPHORYLATION, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, UBL CONJUGATION
2cgw:A (GLU22) to (PHE83) IDENTIFICATION OF CHEMICALLY DIVERSE CHK1 INHIBITORS BY RECEPTOR-BASED VIRTUAL SCREENING | TRANSFERASE, DOCKING, DRUG DESIGN, ONCOLOGY, VIRTUAL SCREENING, ATP- BINDING, CELL CYCLE, DNA DAMAGE, DNA REPAIR, KINASE, NUCLEAR PROTEIN, NUCLEOTIDE-BINDING, PHOSPHORYLATION, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, UBL CONJUGATION
2cgx:A (TYR20) to (PHE83) IDENTIFICATION OF CHEMICALLY DIVERSE CHK1 INHIBITORS BY RECEPTOR-BASED VIRTUAL SCREENING | TRANSFERASE, DOCKING, DRUG DESIGN, ONCOLOGY, VIRTUAL SCREENING, ATP- BINDING, CELL CYCLE, DNA DAMAGE, DNA REPAIR, KINASE, NUCLEAR PROTEIN, NUCLEOTIDE-BINDING, PHOSPHORYLATION, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, UBL CONJUGATION
2cin:A (ASP381) to (PRO426) LYSINE AMINOTRANSFERASE FROM M. TUBERCULOSIS IN THE INTERNAL ALDIMINE FORM | TRANSFERASE, INTERNAL ALDIMINE, PYRIDOXAL PHOSPHATE, PLP, RV3290C, AMINOTRANSFERASE, LYSINE AMINO TRANSFERASE, MYCOBACTERIUM TUBERCULOSIS
2cjd:A (ASP381) to (PRO426) LYSINE AMINOTRANSFERASE FROM M. TUBERCULOSIS IN EXTERNAL ALDIMINE FORM | TRANSFERASE, INTERNAL ALDIMINE, PYRIDOXAL PHOSPHATE, PLP, RV3290C, AMINOTRANSFERASE, LYSINE AMINO TRANSFERASE, MYCOBACTERIUM TUBERCULOSIS
2cjg:A (ASP381) to (PRO426) LYSINE AMINOTRANSFERASE FROM M. TUBERCULOSIS IN BOUND PMP FORM | TRANSFERASE, INTERNAL ALDIMINE, PYRIDOXAL PHOSPHATE, PLP, RV3290C, AMINOTRANSFERASE, LYSINE AMINO TRANSFERASE, MYCOBACTERIUM TUBERCULOSIS
1dco:H (GLY24) to (THR79) DCOH, A BIFUNCTIONAL PROTEIN-BINDING TRANSCRIPTIONAL COACTIVATOR | TRANSCRIPTIONAL STIMULATOR, DIMERIZATION COFACTOR, DEHYDRATASE, 4A-CARBINOLAMINE DEHYDRATASE, TRANSREGULATOR OF HOMEODOMAIN PROTEINS
1dcp:H (GLY24) to (THR79) DCOH, A BIFUNCTIONAL PROTEIN-BINDING TRANSCRIPTIONAL COACTIVATOR, COMPLEXED WITH BIOPTERIN | TRANSCRIPTIONAL STIMULATOR, DIMERIZATION COFACTOR, DEHYDRATASE, 4A-CARBINOLAMINE DEHYDRATASE, TRANSREGULATOR OF HOMEODOMAIN PROTEINS
2qhf:A (ARG3) to (GLY78) MYCOBACTERIUM TUBERCULOSIS CHORISMATE SYNTHASE IN COMPLEX WITH NCA | LYASE
2qhm:A (GLU22) to (PHE83) CRYSTAL STRUCTURE OF CHEK1 IN COMPLEX WITH INHIBITOR 2A | CHEK1, KINASE, CELL CYCLE CHECKPOINT, TRANSFERASE
1dfa:A (ASP326) to (GLY388) CRYSTAL STRUCTURE OF PI-SCEI IN C2 SPACE GROUP | INTEIN, HOMING ENDONUCLEASE, HYDROLASE
2ckq:B (ASN122) to (GLN207) CRYSTAL STRUCTURE OF HUMAN CHOLINE KINASE ALPHA 2 IN COMPLEX WITH PHOSPHOCHOLINE | TRANSFERASE, PHOSPHATIDYLCHOLINE, PHOSPHOLIPID SYNTHESIS
2cn8:A (LYS235) to (VAL300) CRYSTAL STRUCTURE OF HUMAN CHK2 IN COMPLEX WITH DEBROMOHYMENIALDISINE | ATP-BINDING, TRANSFERASE, KINASE DOMAIN, PHOSPHORYLATION, TUMOUR SUPPRESSOR, ACTIVATION SEGMENT, LI-FRAUMENI SYNDROME, SERINE/THREONINE-PROTEIN KINASE, CHK2, CDS1, RAD53, CHEK2, KINASE, CANCER, CHECKPOINT, NUCLEOTIDE-BINDING, HYPOTHETICAL PROTEIN
2qkw:B (LYS54) to (LYS115) STRUCTURAL BASIS FOR ACTIVATION OF PLANT IMMUNITY BY BACTERIAL EFFECTOR PROTEIN AVRPTO | THREE-HELIX BUNDLE MOTIF, AVRPTO-PTO DUPLEX, LAYERED BETA- SHEETS, KINASE, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3gc0:A (GLY27) to (GLU92) STRUCTURE OF THE CMGC CDK KINASE FROM GIARDIA LAMBLIA IN COMPLEX WITH AMP | SSGCID, KINASE, CMGC CDK, AMP, ATP-BINDING, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE
4xv1:B (GLY518) to (GLY593) B-RAF KINASE V600E ONCOGENIC MUTANT IN COMPLEX WITH PLX7904 | B-RAF, BRAF, PROTO-ONCOGENE, V600E, KINASE, TRANSFERASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
2qnu:A (GLU149) to (GLN199) CRYSTAL STRUCTURE OF PA0076 FROM PSEUDOMONAS AERUGINOSA PAO1 AT 2.05 A RESOLUTION | STRUCTURAL GENOMICS, PSEUDOMONAS AERUGINOSA PA01, UNCHARACTERIZED PROTEIN, UNKNOWN FUNCTION, PSI-2, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG
4xv2:A (THR470) to (GLN530) B-RAF KINASE V600E ONCOGENIC MUTANT IN COMPLEX WITH DABRAFENIB | B-RAF, BRAF, PROTO-ONCOGENE, V600E, KINASE, TRANSFERASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
4xv3:A (GLY469) to (GLN530) B-RAF KINASE V600E ONCOGENIC MUTANT IN COMPLEX WITH PLX7922 | B-RAF, BRAF, PROTO-ONCOGENE, V600E, KINASE, TRANSFERASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
4xv3:B (TYR472) to (GLN530) B-RAF KINASE V600E ONCOGENIC MUTANT IN COMPLEX WITH PLX7922 | B-RAF, BRAF, PROTO-ONCOGENE, V600E, KINASE, TRANSFERASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
4xv9:A (GLY469) to (GLN530) B-RAF KINASE DOMAIN IN COMPLEX WITH PLX5568 | B-RAF, BRAF, PROTO-ONCOGENE, V600E, KINASE, TRANSFERASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
2qoj:Z (GLU148) to (THR204) COEVOLUTION OF A HOMING ENDONUCLEASE AND ITS HOST TARGET SEQUENCE | LAGLIDADG HOMING ENDONUCLEASE, I-ANII, HYDROLASE, INTRON HOMING, MITOCHONDRION, MRNA PROCESSING, MRNA SPLICING, HYDROLASE/DNA COMPLEX
3gfh:A (ALA126) to (GLY192) CRYSTAL STRUCTURE OF EUTL SHELL PROTEIN OF THE BACTERIAL ETHANOLAMINE MICROMPARTMENT | BACTERIAL MIRCOCOMPARTMENT, SHELL PROTEIN, ETHANOLAMINE, STRUCTURAL PROTEIN
1dq3:A (GLU250) to (GLU302) CRYSTAL STRUCTURE OF AN ARCHAEAL INTEIN-ENCODED HOMING ENDONUCLEASE PI-PFUI | ENDONUCLEASE, PI-PFUI, INTEIN-ENCODED, HYDROLASE
3ggf:B (GLY36) to (GLU100) CRYSTAL STRUCTURE OF HUMAN SERINE/THREONINE-PROTEIN KINASE MST4 IN COMPLEX WITH AN QUINAZOLIN | SERINE/THREONINE-PROTEIN KINASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, APOPTOSIS, ATP-BINDING, GOLGI APPARATUS, KINASE, MAGNESIUM, METAL-BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, TRANSFERASE
2cw7:A (GLU288) to (LYS340) CRYSTAL STRUCTURE OF INTEIN HOMING ENDONUCLEASE II | HYDROLASE
2cw8:A (GLU288) to (LYS340) CRYSTAL STRUCTURE OF INTEIN HOMING ENDONUCLEASE II | HYDROLASE
3gif:A (THR302) to (PRO366) CRYSTAL STRUCTURE OF DESKC_H188E IN COMPLEX WITH ADP | FOUR-HELIX BUNDLE, GHL ATPASE DOMAIN, CELL MEMBRANE, KINASE, MEMBRANE, PHOSPHOPROTEIN, TRANSFERASE, TRANSMEMBRANE, TWO-COMPONENT REGULATORY SYSTEM
3gig:A (LYS301) to (PRO366) CRYSTAL STRUCTURE OF PHOSPHORYLATED DESKC IN COMPLEX WITH AMP-PCP | FOUR-HELIX BUNDLE, GHL ATPASE DOMAIN, CELL MEMBRANE, KINASE, MEMBRANE, PHOSPHOPROTEIN, TRANSFERASE, TRANSMEMBRANE, TWO-COMPONENT REGULATORY SYSTEM
3gig:B (LYS301) to (PRO366) CRYSTAL STRUCTURE OF PHOSPHORYLATED DESKC IN COMPLEX WITH AMP-PCP | FOUR-HELIX BUNDLE, GHL ATPASE DOMAIN, CELL MEMBRANE, KINASE, MEMBRANE, PHOSPHOPROTEIN, TRANSFERASE, TRANSMEMBRANE, TWO-COMPONENT REGULATORY SYSTEM
1px5:B (PRO51) to (SER136) CRYSTAL STRUCTURE OF THE 2'-SPECIFIC AND DOUBLE-STRANDED RNA-ACTIVATED INTERFERON-INDUCED ANTIVIRAL PROTEIN 2'-5'- OLIGOADENYLATE SYNTHETASE | 5-STRANDED ANTIPARALEL BETA SHEET, FOUR HELIX BUNDLE, TRANSFERASE
2dch:X (ASP106) to (ILE163) CRYSTAL STRUCTURE OF ARCHAEAL INTRON-ENCODED HOMING ENDONUCLEASE I- TSP061I | ALPHA/BETA FOLD, HYDROLASE
1pyx:B (GLY68) to (ASP133) GSK-3 BETA COMPLEXED WITH AMP-PNP | KINASE, INSULIN PATHWAY, TRANSFERASE
3teg:A (PHE135) to (ASN244) BACTERIAL AND EUKARYOTIC PHENYLALANYL-TRNA SYNTHETASES CATALYZE MISAMINOACYLATION OF TRNAPHE WITH 3,4-DIHYDROXY-L-PHENYLALANINE (L- DOPA) | DOPA, L-DOPA, TRNA, LIGASE
3gtg:K (LYS18) to (THR78) BACKTRACKED RNA POLYMERASE II COMPLEX WITH 12MER RNA | TRANSCRIPTION, TRANSFERASE/DNA-RNA HYBRID, DNA-DIRECTED RNA POLYMERASE, DNA BINDING, ISOPEPTIDE BOND, MAGNESIUM, METAL BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA DAMAGE, DNA REPAIR, TRANSFERASE/DNA/RNA HYBRID COMPLEX
3tf1:A (GLY111) to (LYS179) CRYSTAL STRUCTURE OF AN H-NOX PROTEIN FROM T. TENGCONGENSIS UNDER 6 ATM OF XENON | HEME-BASED METHYL-ACCEPTING CHEMOTAXIS PROTEIN, GAS BINDING, SIGNALING PROTEIN
3tf9:A (ALA119) to (ASP183) CRYSTAL STRUCTURE OF AN H-NOX PROTEIN FROM NOSTOC SP. PCC 7120 UNDER 1 ATM OF XENON | HEME-BASED SENSOR DOMAIN, GAS BINDING, SIGNALING PROTEIN
3tf9:B (ALA119) to (ASP183) CRYSTAL STRUCTURE OF AN H-NOX PROTEIN FROM NOSTOC SP. PCC 7120 UNDER 1 ATM OF XENON | HEME-BASED SENSOR DOMAIN, GAS BINDING, SIGNALING PROTEIN
3tfg:B (ALA119) to (GLU182) CRYSTAL STRUCTURE OF AN H-NOX PROTEIN FROM NOSTOC SP. PCC 7120, L66W/L67W DOUBLE MUTANT | HEME-BASED SENSOR DOMAIN, GAS BINDING, SIGNALING PROTEIN
1q1l:A (TYR5) to (ARG82) CRYSTAL STRUCTURE OF CHORISMATE SYNTHASE | BETA ALPHA BETA SANDWICH, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, LYASE
1q1l:B (TYR5) to (ARG82) CRYSTAL STRUCTURE OF CHORISMATE SYNTHASE | BETA ALPHA BETA SANDWICH, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, LYASE
1q1l:C (TYR5) to (ARG82) CRYSTAL STRUCTURE OF CHORISMATE SYNTHASE | BETA ALPHA BETA SANDWICH, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, LYASE
1q1l:D (TYR5) to (ASP85) CRYSTAL STRUCTURE OF CHORISMATE SYNTHASE | BETA ALPHA BETA SANDWICH, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, LYASE
3tgo:C (GLY94) to (ASP144) CRYSTAL STRUCTURE OF THE E. COLI BAMCD COMPLEX | LIPOPROTEIN COMPLEX, TPR REPEAT, HELIX-GRIP FOLD, OUTER MEMBRANE PROTEIN ASSEMBLY, OUTER MEMBRANE, MEMBRANE PROTEIN
1q3d:B (GLY68) to (LEU130) GSK-3 BETA COMPLEXED WITH STAUROSPORINE | KINASE, INSULIN PATHWAY, TRANSFERASE
3gtp:K (LYS18) to (THR77) BACKTRACKED RNA POLYMERASE II COMPLEX WITH 24MER RNA | TRANSCRIPTION, TRANSFERASE, DNA-RNA HYBRID, BACKTRACK, DNA- DIRECTED RNA POLYMERASE, DNA BINDING, ISOPEPTIDE BOND, MAGNESIUM, METAL BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA DAMAGE, DNA REPAIR, TRANSFERASE/DNA-RNA HYBRID COMPLEX
4jd2:D (THR151) to (PRO229) CRYSTAL STRUCTURE OF BOS TAURUS ARP2/3 COMPLEX BINDING WITH MUS MUSCULUS GMF | ACTIN FILAMENT POLYMERIZATION AND BRANCHING, STRUCTURAL PROTEIN
4jdi:A (ILE334) to (MET395) CRYSTAL STRUCTURE OF SERINE/THREONINE-PROTEIN KINASE PAK 4 IN COMPLEX WITH PAKTIDE S PEPTIDE SUBSTRATE | TRANSFERASE-PEPTIDE COMPLEX, TRANSFERASE/PEPTIDE, SERINE/THREONINE- PROTEIN KINASE PAK4, ATP BINDING, PHOSPHORYLATION
4jdj:A (GLY333) to (MET395) CRYSTAL STRUCTURE OF SERINE/THREONINE-PROTEIN KINASE PAK 4 F461V MUTANT IN COMPLEX WITH PAKTIDE T PEPTIDE SUBSTRATE | TRANSFERASE-PEPTIDE COMPLEX, TRANSFERASE/PEPTIDE, SERINE/THREONINE- PROTEIN KINASE PAK4, ATP BINDING, PHOSPHORYLATION
4jdk:A (GLY333) to (MET395) CRYSTAL STRUCTURE OF SERINE/THREONINE-PROTEIN KINASE PAK 4 F461V MUTANT IN COMPLEX WITH PAKTIDE S PEPTIDE SUBSTRATE | TRANSFERASE-PEPTIDE COMPLEX, TRANSFERASE/PEPTIDE, SERINE/THREONINE- PROTEIN KINASE PAK4, ATP BINDING, PHOSPHORYLATION
1ef0:B (ASP326) to (GLY388) CRYSTAL STRUCTURE OF PI-SCEI MINIPRECURSOR | ENDONUCLEASE, PROTEIN SPLICING, MINI-PRECURSOR, HYDROLASE
2r9s:B (ASN128) to (ASP207) C-JUN N-TERMINAL KINASE 3 WITH 3,5-DISUBSTITUTED QUINOLINE INHIBITOR | JNK3, SIGNALING PROTEIN, TRANSFERASE
4jg2:A (ASN14) to (LYS104) STRUCTURE OF PHAGE-RELATED PROTEIN FROM BACILLUS CEREUS ATCC 10987 | STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, STRUCTURES OF MTB PROTEINS CONFERRING SUSCEPTIBILITY TO KNOWN MTB INHIBITORS, MTBI, PHAGE-RELATED PROTEIN, UNKNOWN FUNCTION
1ej6:A (LYS171) to (LEU238) REOVIRUS CORE | VIRUS, ICOSAHEDRAL, NON-EQUIVALENCE, DSRNA VIRUS, METHYLASE, METHYLTRANSFERASE, GUANYLYLTRANSFERASE, ZINC FINGER, ICOSAHEDRAL VIRUS
2rio:A (THR30) to (GLU89) STRUCTURE OF THE DUAL ENZYME IRE1 REVEALS THE BASIS FOR CATALYSIS AND REGULATION OF NON-CONVENTIONAL SPLICING | PROTEIN-NUCLEOTIDE COMPLEX, ATP-BINDING, ENDOPLASMIC RETICULUM, GLYCOPROTEIN, HYDROLASE, KINASE, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE- BINDING, PHOSPHORYLATION, SERINE/THREONINE-PROTEIN KINASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UNFOLDED PROTEIN RESPONSE
2rjz:A (GLU129) to (TYR198) CRYSTAL STRUCTURE OF THE TYPE 4 FIMBRIAL BIOGENESIS PROTEIN PILO FROM PSEUDOMONAS AERUGINOSA | STRUCTURAL GENOMICS, UNKNOWN FUNCTION, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
4jnw:A (GLY36) to (ILE96) BACTERIALLY EXPRESSED TITIN KINASE | MUSCLE CYTOSKELETON, TRANSFERASE
4jqh:A (GLN114) to (GLU182) CRYSTAL STRUCTURE OF A NEW SGC ACTIVATOR (ANALOGUE OF BAY 58-2667) BOUND TO NOSTOC H-NOX DOMAIN | GUANYLYL CYCLASE, ANALOGUE OF BAY58-2667, SIGNALING PROTEIN
4jqh:B (GLN114) to (GLU182) CRYSTAL STRUCTURE OF A NEW SGC ACTIVATOR (ANALOGUE OF BAY 58-2667) BOUND TO NOSTOC H-NOX DOMAIN | GUANYLYL CYCLASE, ANALOGUE OF BAY58-2667, SIGNALING PROTEIN
1qpe:A (GLY257) to (GLU317) STRUCTURAL ANALYSIS OF THE LYMPHOCYTE-SPECIFIC KINASE LCK IN COMPLEX WITH NON-SELECTIVE AND SRC FAMILY SELECTIVE KINASE INHIBITORS | ALPHA BETA FOLD, TRANSFERASE
4yit:A (GLU169) to (VAL227) CRYSTAL STRUCTURE OF LAGLIDADG MEGANUCLEASE I-AABMI BOUND TO UNCLEAVED DNA | HYDROLASE-DNA COMPLEX, LAGLIDADG, HOMING ENDONUCLEASE, MEGANUCLEASE
4yit:D (GLU169) to (SER228) CRYSTAL STRUCTURE OF LAGLIDADG MEGANUCLEASE I-AABMI BOUND TO UNCLEAVED DNA | HYDROLASE-DNA COMPLEX, LAGLIDADG, HOMING ENDONUCLEASE, MEGANUCLEASE
3h5n:D (LYS202) to (PRO252) CRYSTAL STRUCTURE OF E. COLI MCCB + ATP | UBIQUITIN-ACTIVATING ENZYME, MICROCIN, PROTEIN STRUCTURE, MCCC7, PEPTIDE ANTIBIOTICS, N-P BOND FORMATION, TRANSFERASE
3h5r:D (LYS202) to (PRO252) CRYSTAL STRUCTURE OF E. COLI MCCB + SUCCINIMIDE | UBIQUITIN-ACTIVATING ENZYME, MICROCIN, BACTERIOCIN, MCC7, PEPTIDE ANTIBIOTIC, N-P BOND FORMATION, ANTIBIOTIC, ANTIMICROBIAL, PHOSPHOPROTEIN, TRANSFERASE, TRANSFERASE-ANTIBIOTIC COMPLEX
3tz7:B (GLY279) to (GLU339) KINASE DOMAIN OF CSRC IN COMPLEX WITH RL103 | TYPE II, ALLOSTERIC, DFG-OUT, DRUG RESISTANCE MUTATIONS, TYROSIN- PROTEIN KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2uuv:D (GLY135) to (ASP193) ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE IN P1 | RHIZOMELIC CHONDRODYSPLASIA PUNCTATA, BIOSYNTHESIS OF PHOSPHOLIPIDS, FLAVOPROTEIN, LIPID SYNTHESIS, PEROXISOMAL DISORDER, FAD, FLAVIN, PEROXISOME, TRANSFERASE, PLASMALOGENS
1f3m:D (GLY282) to (GLU345) CRYSTAL STRUCTURE OF HUMAN SERINE/THREONINE KINASE PAK1 | KINASE DOMAIN, AUTOINHIBITORY FRAGMENT, HOMODIMER, TRANSFERASE
4ykn:A (TRP1780) to (ASN1853) PI3K ALPHA LIPID KINASE WITH ACTIVE SITE INHIBITOR | "LIPID KINASE", INHIBITOR, COMPLEX, PI3K, PI3K ALPHA, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3h7f:B (GLY306) to (GLY365) CRYSTAL STRUCTURE OF SERINE HYDROXYMETHYLTRANSFERASE FROM MYCOBACTERIUM TUBERCULOSIS | MYCOBACTERIUM TUBERCULOSIS, SERINE HYDROXYMETHYLTRANSFERASE, ONE- CARBON METABOLISM, PYRIDOXAL PHOSPHATE, TRANSFERASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID
2e9n:A (GLY21) to (PHE83) STRUCTURE OF H-CHK1 COMPLEXED WITH A767085 | PROTEIN-INHIBITOR COMPLEX, TRANSFERASE
3h9g:A (LYS202) to (PRO252) CRYSTAL STRUCTURE OF E. COLI MCCB + MCCA-N7ISOASN | UBIQUITIN-ACTIVATING ENZYME, MICROCIN, BACTERIOCIN, MCC7, PEPTIDE ANTIBIOTIC, N-P BOND FORMATION, ANTIBIOTIC, ANTIMICROBIAL, PHOSPHOPROTEIN, TRANSFERASE, TRANSFERASE-ANTIBIOTIC COMPLEX
3h9g:D (LYS202) to (PRO252) CRYSTAL STRUCTURE OF E. COLI MCCB + MCCA-N7ISOASN | UBIQUITIN-ACTIVATING ENZYME, MICROCIN, BACTERIOCIN, MCC7, PEPTIDE ANTIBIOTIC, N-P BOND FORMATION, ANTIBIOTIC, ANTIMICROBIAL, PHOSPHOPROTEIN, TRANSFERASE, TRANSFERASE-ANTIBIOTIC COMPLEX
4jvg:B (LYS473) to (GLN530) B-RAF KINASE IN COMPLEX WITH BIRB796 | KINASE, PHOSPHOTRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4jvg:C (LYS473) to (GLN530) B-RAF KINASE IN COMPLEX WITH BIRB796 | KINASE, PHOSPHOTRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3hgk:A (LYS54) to (LYS115) CRYSTAL STRUCTURE OF EFFECT PROTEIN AVRPTOB COMPLEXED WITH KINASE PTO | FIVE HELICES, PTO P+1 LOOP, ATP-BINDING, KINASE, NUCLEOTIDE- BINDING, SERINE/THREONINE-PROTEIN KINASE, HYPERSENSITIVE RESPONSE ELICITATION, LIGASE, SECRETED, UBL CONJUGATION, UBL CONJUGATION PATHWAY, VIRULENCE, TRANSFERASE
3hgk:B (LYS54) to (LYS115) CRYSTAL STRUCTURE OF EFFECT PROTEIN AVRPTOB COMPLEXED WITH KINASE PTO | FIVE HELICES, PTO P+1 LOOP, ATP-BINDING, KINASE, NUCLEOTIDE- BINDING, SERINE/THREONINE-PROTEIN KINASE, HYPERSENSITIVE RESPONSE ELICITATION, LIGASE, SECRETED, UBL CONJUGATION, UBL CONJUGATION PATHWAY, VIRULENCE, TRANSFERASE
3hgk:C (GLY53) to (LYS115) CRYSTAL STRUCTURE OF EFFECT PROTEIN AVRPTOB COMPLEXED WITH KINASE PTO | FIVE HELICES, PTO P+1 LOOP, ATP-BINDING, KINASE, NUCLEOTIDE- BINDING, SERINE/THREONINE-PROTEIN KINASE, HYPERSENSITIVE RESPONSE ELICITATION, LIGASE, SECRETED, UBL CONJUGATION, UBL CONJUGATION PATHWAY, VIRULENCE, TRANSFERASE
3hgk:D (LYS54) to (LYS115) CRYSTAL STRUCTURE OF EFFECT PROTEIN AVRPTOB COMPLEXED WITH KINASE PTO | FIVE HELICES, PTO P+1 LOOP, ATP-BINDING, KINASE, NUCLEOTIDE- BINDING, SERINE/THREONINE-PROTEIN KINASE, HYPERSENSITIVE RESPONSE ELICITATION, LIGASE, SECRETED, UBL CONJUGATION, UBL CONJUGATION PATHWAY, VIRULENCE, TRANSFERASE
4yno:A (GLY37) to (PRO108) CRYSTAL STRUCTURE OF MAPK13 AT INACTIVE FORM | P38 KINASE, TRANSFERASE
1fg3:A (GLU290) to (THR337) CRYSTAL STRUCTURE OF L-HISTIDINOL PHOSPHATE AMINOTRANSFERASE COMPLEXED WITH L-HISTIDINOL | AMINOTRANSFERASE, HISC, HISTIDINE BIOSYNTHESIS, PYRIDOXAL PHOSPHATE, TRANSFERASE
1fg7:A (GLU290) to (THR337) CRYSTAL STRUCTURE OF L-HISTIDINOL PHOSPHATE AMINOTRANSFERASE WITH PYRIDOXAL-5'-PHOSPHATE | AMINOTRANSFERASE, HISC, HISTIDINE BIOSYNTHESIS, PYRIDOXAL PHOSPHATE, MONTREAL-KINGSTON BACTERIAL STRUCTURAL GENOMICS INITIATIVE, BSGI, STRUCTURAL GENOMICS, TRANSFERASE
2v1p:A (GLN353) to (ILE422) CRYSTAL STRUCTURE OF THE APO FORM OF Y74F MUTANT E. COLI TRYPTOPHANASE | LYASE, PYRIDOXAL PHOSPHATE, TRYPTOPHAN CATABOLISM
1fhi:A (SER22) to (PRO101) SUBSTRATE ANALOG (IB2) COMPLEX WITH THE FRAGILE HISTIDINE TRIAD PROTEIN, FHIT | NUCLEOTIDE-BINDING PROTEIN, CANCER, DIADENOSINE TRIPHOSPHATE HYDROLASE, HISTIDINE TRIAD, TUMOR SUPPRESSOR
1fit:A (SER22) to (PRO101) FHIT (FRAGILE HISTIDINE TRIAD PROTEIN) | FHIT, FRAGILE HISTIDINE TRIAD PROTEIN, PUTATIVE HUMAN TUMOR SUPPRESSOR, ADVANCED PHOTON SOURCE, APS, HIT PROTEIN FAMILY, PKCI, CHROMOSOMAL TRANSLOCATION
2eva:A (ALA53) to (GLU105) STRUCTURAL BASIS FOR THE INTERACTION OF TAK1 KINASE WITH ITS ACTIVATING PROTEIN TAB1 | TAK1, TAB1, KINASE, TRANSFERASE/TRANSFERASE ACTIVATOR COMPLEX
1fnw:A (LYS115) to (ASP185) CRYSTAL STRUCTURE OF STREPTOCOCCAL PYROGENIC EXOTOXIN A | EXOTOXIN A, SUPERANTIGEN
1fnw:B (LYS415) to (ASP485) CRYSTAL STRUCTURE OF STREPTOCOCCAL PYROGENIC EXOTOXIN A | EXOTOXIN A, SUPERANTIGEN
1fnw:H (LYS2215) to (ASP2285) CRYSTAL STRUCTURE OF STREPTOCOCCAL PYROGENIC EXOTOXIN A | EXOTOXIN A, SUPERANTIGEN
2v6t:B (GLN23) to (GLU75) CRYSTAL STRUCTURE OF A COMPLEX OF PTERIN-4A-CARBINOLAMINE DEHYDRATASE FROM TOXOPLASMA GONDII WITH 7,8- DIHYDROBIOPTERIN | LYASE, PTERIN, ENZYME, TAUTOMER, TOXOPLASMA, DEHYDRATASE
2v6u:A (GLN23) to (THR78) HIGH RESOLUTION CRYSTAL STRUCTURE OF PTERIN-4A- CARBINOLAMINE DEHYDRATASE FROM TOXOPLASMA GONDII | LYASE, PTERIN, ENZYME, TOXOPLASMA, DEHYDRATASE
2v6u:B (GLN23) to (THR78) HIGH RESOLUTION CRYSTAL STRUCTURE OF PTERIN-4A- CARBINOLAMINE DEHYDRATASE FROM TOXOPLASMA GONDII | LYASE, PTERIN, ENZYME, TOXOPLASMA, DEHYDRATASE
3ujg:A (VAL34) to (GLU95) CRYSTAL STRUCTURE OF SNRK2.6 IN COMPLEX WITH HAB1 | SNRK2.6, KINASE, PROTEIN PHOSPHATASE 2C, ABA SIGNALING, SIGNALING PROTEIN
3ukr:D (ASP149) to (PRO229) CRYSTAL STRUCTURE OF BOS TAURUS ARP2/3 COMPLEX WITH BOUND INHIBITOR CK-666 | BETA-PROPELLER ACTIN FOLD, STRUCTURAL PROTEIN, ATP BINDING
3ule:D (ASP149) to (PRO229) STRUCTURE OF BOS TAURUS ARP2/3 COMPLEX WITH BOUND INHIBITOR CK-869 AND ATP | BETA-PROPELLOR, STRUCTURAL PROTEIN, ACTIN FILAMENT NUCLEATOR
4yzd:B (CYS630) to (ILE709) CRYSTAL STRUCTURE OF HUMAN PHOSPHORYLATED IRE1ALPHA IN COMPLEX WITH ADP-MG | ACTIVE, ADP, COMPLEX, IRE1, TRANSFERASE
4yzn:A (GLY1038) to (GLU1106) HUMANIZED ROCO4 BOUND TO COMPOUND 19 | ROCO-PROTEIN, KINASE, LRRK2, INHIBITOR, ROCO4, TRANSFERASE
4kd1:A (GLY16) to (GLU81) CDK2 IN COMPLEX WITH DINACICLIB | PROTEIN KINASE, DINACICLIB, TRANSFERASE-TRANSFERASE, CELL CYCLE- INHIBITOR COMPLEX
3uok:B (GLY145) to (ILE209) AURORA A IN COMPLEX WITH YL5-81-1 | PROTEIN KINASE, AURORA A, INHIBITOR, DFG-OUT, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1g71:A (ALA76) to (ASP156) CRYSTAL STRUCTURE OF PYROCOCCUS FURIOSUS DNA PRIMASE | ZINC-KNUCKLE, REPLICATION
3hox:K (LEU19) to (THR77) COMPLETE RNA POLYMERASE II ELONGATION COMPLEX V | RNA POLYMERASE II, METAL-BINDING, TRANSCRIPTION BUBBLE, ELONGATION COMPLEX, TRANSCRIPTION, DNA-RNA MISMATCH, DNA- BINDING, DNA-DIRECTED RNA POLYMERASE, ISOPEPTIDE BOND, MAGNESIUM, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA DAMAGE, DNA REPAIR, MRNA PROCESSING, TRANSCRIPTION,TRANSFERASE/DNA/RNA HYBRID COMPLEX
3hoy:K (LYS18) to (THR78) COMPLETE RNA POLYMERASE II ELONGATION COMPLEX VI | RNA POLYMERASE II, METAL-BINDING, TRANSCRIPTION BUBBLE, ELONGATION COMPLEX, TRANSCRIPTION, DNA-RNA MISMATCH, RNA FRAYING, DNA-BINDING, DNA-DIRECTED RNA POLYMERASE, ISOPEPTIDE BOND, MAGNESIUM, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA DAMAGE, DNA REPAIR, MRNA PROCESSING, TRANSCRIPTION,TRANSFERASE/DNA/RNA HYBRID COMPLEX
2fhi:A (SER22) to (PRO101) SUBSTRATE ANALOG (IB2) COMPLEX WITH THE HIS 96 ASN SUBSTITUTION OF THE FRAGILE HISTIDINE TRIAD PROTEIN, FHIT | NUCLEOTIDE-BINDING PROTEIN, CANCER, DIADENOSINE TRIPHOSPHATE HYDROLASE, ACTIVE SITE SUBSTITUTION, HISTIDINE TRIAD, TUMOR SUPPRESSOR
4zci:B (LEU380) to (PRO444) CRYSTAL STRUCTURE OF ESCHERICHIA COLI GTPASE BIPA/TYPA | BIPA, GTPASE, NUCLEOTIDE, GTP-BINDING PROTEIN
3hvc:A (GLY36) to (HIS107) CRYSTAL STRUCTURE OF HUMAN P38ALPHA MAP KINASE | TRANSFERASE, MAP KINASE, SERINE/THREONINE-PROTEIN KINASE, P38, ISOFORM-2, ALTERNATIVE SPLICING, ATP-BINDING, CYTOPLASM, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM
2fsm:X (GLY36) to (HIS107) MITOGEN ACTIVATED PROTEIN KINASE P38ALPHA (D176A+F327S) ACTIVATING MUTANT FORM-B | MITOGEN ACTIVATED PROTEIN KINASE, P38, ACTIVE MUTANTS, LIPIDS, MAP KINASE INSERTION, AUTOPHOSPHORYLATION, TRANSFERASE
3hxa:D (GLY24) to (THR79) CRYSTAL STRUCTURE OF DCOH1THR51SER | ALPHA AND BETA STRUCTURE, LYASE, NUCLEUS, TETRAHYDROBIOPTERIN BIOSYNTHESIS
3hxa:G (GLY24) to (THR79) CRYSTAL STRUCTURE OF DCOH1THR51SER | ALPHA AND BETA STRUCTURE, LYASE, NUCLEUS, TETRAHYDROBIOPTERIN BIOSYNTHESIS
3hxa:H (GLY24) to (THR79) CRYSTAL STRUCTURE OF DCOH1THR51SER | ALPHA AND BETA STRUCTURE, LYASE, NUCLEUS, TETRAHYDROBIOPTERIN BIOSYNTHESIS
3hyi:A (ARG39) to (GLU94) CRYSTAL STRUCTURE OF FULL-LENGTH DUF199/WHIA FROM THERMATOGA MARITIMA | LAGLIDADG, HOMING ENDONUCLEASE, HELIX-TURN-HELIX, HTH, TRANSCRIPTION REGULATOR
3hyi:A (GLY123) to (SER174) CRYSTAL STRUCTURE OF FULL-LENGTH DUF199/WHIA FROM THERMATOGA MARITIMA | LAGLIDADG, HOMING ENDONUCLEASE, HELIX-TURN-HELIX, HTH, TRANSCRIPTION REGULATOR
3hyj:A (ARG39) to (GLU97) CRYSTAL STRUCTURE OF THE N-TERMINAL LAGLIDADG DOMAIN OF DUF199/WHIA | LAGLIDADG, HOMING ENDONUCLEASE, HELIX-TURN-HELIX, HTH, TRANSCRIPTION REGULATOR
3hyj:A (GLY122) to (SER174) CRYSTAL STRUCTURE OF THE N-TERMINAL LAGLIDADG DOMAIN OF DUF199/WHIA | LAGLIDADG, HOMING ENDONUCLEASE, HELIX-TURN-HELIX, HTH, TRANSCRIPTION REGULATOR
3hyj:D (ARG39) to (GLU94) CRYSTAL STRUCTURE OF THE N-TERMINAL LAGLIDADG DOMAIN OF DUF199/WHIA | LAGLIDADG, HOMING ENDONUCLEASE, HELIX-TURN-HELIX, HTH, TRANSCRIPTION REGULATOR
4zg6:A (ASP382) to (VAL448) STRUCTURAL BASIS FOR INHIBITION OF HUMAN AUTOTAXIN BY FOUR NOVEL COMPOUNDS | AUTOTAXIN, ENPP2, INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4zg6:B (ASP382) to (VAL448) STRUCTURAL BASIS FOR INHIBITION OF HUMAN AUTOTAXIN BY FOUR NOVEL COMPOUNDS | AUTOTAXIN, ENPP2, INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4zg9:B (ASP382) to (GLU449) STRUCTURAL BASIS FOR INHIBITION OF HUMAN AUTOTAXIN BY FOUR NOVEL COMPOUNDS | AUTOTAXIN, ENPP2, INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3i0o:A (ASN36) to (PRO101) CRYSTAL STRUCTURE OF SPECTINOMYCIN PHOSPHOTRANSFERASE, APH(9)-IA, IN COMPLEX WITH ADP AND SPECTINOMCYIN | PROTEIN KINASE, AMINOGLYCOSIDE PHOSPHOTRANSFERASE, ANTIBIOTIC RESISTANCE, TRANSFERASE
4ksq:A (GLY468) to (GLN529) CRYSTAL STRUCTURE OF HUMAN B-RAF BOUND TO A DFG-OUT INHIBITOR 5B | HUMAN SERINE/THERONINE PROTEIN KINASE, KINASE DRUG COMPLEX,, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ksq:B (LYS472) to (GLN529) CRYSTAL STRUCTURE OF HUMAN B-RAF BOUND TO A DFG-OUT INHIBITOR 5B | HUMAN SERINE/THERONINE PROTEIN KINASE, KINASE DRUG COMPLEX,, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2vta:A (GLY16) to (PHE80) IDENTIFICATION OF N-(4-PIPERIDINYL)-4-(2,6- DICHLOROBENZOYLAMINO)-1H-PYRAZOLE-3-CARBOXAMIDE (AT7519), A NOVEL CYCLIN DEPENDENT KINASE INHIBITOR USING FRAGMENT- BASED X-RAY CRYSTALLOGRAPHY AND STRUCTURE BASED DRUG DESIGN. | TRANSFERASE, MITOSIS, CELL CYCLE, CELL DIVISION, SERINE/THREONINE PROTEIN KINASE, PHOSPHORYLATION
4zib:A (PRO319) to (HIS392) CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF PYLRS MUTANT BOUND WITH 3-BENZOTHIENYL-L-ALANINE AND ATP | AMINOACYL-TRNA SYNTHETASES, ARCHAEAL PROTEINS, EVOLUTION, MOLECULAR, GENETIC CODE, SUBSTRATE SPECIFICITY, LIGASE
2g85:A (ARG3) to (GLY78) CRYSTAL STRUCTURE OF CHORISMATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS AT 2.22 ANGSTRONS OF RESOLUTION | BETA-ALPHA-BETA, SHIKIMATE PATHWAY, LYASE
1gup:B (PRO87) to (SER173) STRUCTURE OF NUCLEOTIDYLTRANSFERASE COMPLEXED WITH UDP- GALACTOSE | TRANSFERASE, NUCLEOTIDYLTRANSFERASE, GALACTOSE METABOLISM
1gup:C (PRO87) to (SER173) STRUCTURE OF NUCLEOTIDYLTRANSFERASE COMPLEXED WITH UDP- GALACTOSE | TRANSFERASE, NUCLEOTIDYLTRANSFERASE, GALACTOSE METABOLISM
1gup:D (PRO87) to (SER173) STRUCTURE OF NUCLEOTIDYLTRANSFERASE COMPLEXED WITH UDP- GALACTOSE | TRANSFERASE, NUCLEOTIDYLTRANSFERASE, GALACTOSE METABOLISM
3i6u:A (GLY232) to (GLU302) STRUCTURE AND ACTIVATION MECHANISM OF THE CHK2 DNA-DAMAGE CHECKPOINT KINASE | SER/THR PROTEIN KINASE, FHA DOMAIN, ATP-BINDING, CELL CYCLE, DISEASE MUTATION, KINASE, LI-FRAUMENI SYNDROME, MAGNESIUM, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, PROTO-ONCOGENE, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3i6u:B (GLY232) to (GLU302) STRUCTURE AND ACTIVATION MECHANISM OF THE CHK2 DNA-DAMAGE CHECKPOINT KINASE | SER/THR PROTEIN KINASE, FHA DOMAIN, ATP-BINDING, CELL CYCLE, DISEASE MUTATION, KINASE, LI-FRAUMENI SYNDROME, MAGNESIUM, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, PROTO-ONCOGENE, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
1guq:B (PRO87) to (SER173) STRUCTURE OF NUCLEOTIDYLTRANSFERASE COMPLEXED WITH UDP-GLUCOSE | TRANSFERASE, NUCLEOTIDYLTRANSFERASE, GALACTOSE METABOLISM
1guq:C (ALA89) to (SER173) STRUCTURE OF NUCLEOTIDYLTRANSFERASE COMPLEXED WITH UDP-GLUCOSE | TRANSFERASE, NUCLEOTIDYLTRANSFERASE, GALACTOSE METABOLISM
3i6w:A (LYS235) to (GLU302) STRUCTURE AND ACTIVATION MECHANISM OF THE CHK2 DNA-DAMAGE CHECKPOINT KINASE | SER/THR PROTEIN KINASE, FHA DOMAIN, ATP-BINDING, CELL CYCLE, DISEASE MUTATION, KINASE, LI-FRAUMENI SYNDROME, MAGNESIUM, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, PROTO-ONCOGENE, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3i6w:B (LYS235) to (GLU302) STRUCTURE AND ACTIVATION MECHANISM OF THE CHK2 DNA-DAMAGE CHECKPOINT KINASE | SER/THR PROTEIN KINASE, FHA DOMAIN, ATP-BINDING, CELL CYCLE, DISEASE MUTATION, KINASE, LI-FRAUMENI SYNDROME, MAGNESIUM, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, PROTO-ONCOGENE, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3i6w:C (LYS235) to (GLU302) STRUCTURE AND ACTIVATION MECHANISM OF THE CHK2 DNA-DAMAGE CHECKPOINT KINASE | SER/THR PROTEIN KINASE, FHA DOMAIN, ATP-BINDING, CELL CYCLE, DISEASE MUTATION, KINASE, LI-FRAUMENI SYNDROME, MAGNESIUM, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, PROTO-ONCOGENE, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3i6w:D (LYS235) to (GLU302) STRUCTURE AND ACTIVATION MECHANISM OF THE CHK2 DNA-DAMAGE CHECKPOINT KINASE | SER/THR PROTEIN KINASE, FHA DOMAIN, ATP-BINDING, CELL CYCLE, DISEASE MUTATION, KINASE, LI-FRAUMENI SYNDROME, MAGNESIUM, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, PROTO-ONCOGENE, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3i6w:E (LYS235) to (GLU302) STRUCTURE AND ACTIVATION MECHANISM OF THE CHK2 DNA-DAMAGE CHECKPOINT KINASE | SER/THR PROTEIN KINASE, FHA DOMAIN, ATP-BINDING, CELL CYCLE, DISEASE MUTATION, KINASE, LI-FRAUMENI SYNDROME, MAGNESIUM, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, PROTO-ONCOGENE, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3i6w:F (LYS235) to (GLU302) STRUCTURE AND ACTIVATION MECHANISM OF THE CHK2 DNA-DAMAGE CHECKPOINT KINASE | SER/THR PROTEIN KINASE, FHA DOMAIN, ATP-BINDING, CELL CYCLE, DISEASE MUTATION, KINASE, LI-FRAUMENI SYNDROME, MAGNESIUM, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, PROTO-ONCOGENE, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3i6w:G (LYS235) to (GLU302) STRUCTURE AND ACTIVATION MECHANISM OF THE CHK2 DNA-DAMAGE CHECKPOINT KINASE | SER/THR PROTEIN KINASE, FHA DOMAIN, ATP-BINDING, CELL CYCLE, DISEASE MUTATION, KINASE, LI-FRAUMENI SYNDROME, MAGNESIUM, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, PROTO-ONCOGENE, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3i6w:H (LYS235) to (GLU302) STRUCTURE AND ACTIVATION MECHANISM OF THE CHK2 DNA-DAMAGE CHECKPOINT KINASE | SER/THR PROTEIN KINASE, FHA DOMAIN, ATP-BINDING, CELL CYCLE, DISEASE MUTATION, KINASE, LI-FRAUMENI SYNDROME, MAGNESIUM, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, PROTO-ONCOGENE, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
2gb3:D (ARG309) to (ALA368) CRYSTAL STRUCTURE OF ASPARTATE AMINOTRANSFERASE (TM1698) FROM THERMOTOGA MARITIMA AT 2.50 A RESOLUTION | TM1698, ASPARTATE AMINOTRANSFERASE, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, TRANSFERASE
2gb3:E (ARG309) to (ALA368) CRYSTAL STRUCTURE OF ASPARTATE AMINOTRANSFERASE (TM1698) FROM THERMOTOGA MARITIMA AT 2.50 A RESOLUTION | TM1698, ASPARTATE AMINOTRANSFERASE, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, TRANSFERASE
2vwi:D (THR28) to (LYS93) STRUCTURE OF THE OSR1 KINASE, A HYPERTENSION DRUG TARGET | KINASE, STE KINASE, HYPERTENSION, TRANSFERASE
2gfs:A (SER37) to (THR106) P38 KINASE CRYSTAL STRUCTURE IN COMPLEX WITH RO3201195 | P38; MAP KINASE; SERINE/THREONINE KINASE, SIGNALING PROTEIN, TRANSFERASE
4zk5:B (TYR40) to (GLU106) MAP4K4 IN COMPLEX WITH INHIBITOR GNE-495 | KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4zki:A (VAL525) to (PRO608) THE CRYSTAL STRUCTURE OF HISTIDINE KINASE YYCG WITH ADP | HISTIDINE KINASE, ADP, TRANSFERASE
2gj2:A (ALA2) to (CYS46) CRYSTAL STRUCTURE OF VP9 FROM WHITE SPOT SYNDROME VIRUS | FERREDOXIN FOLD, METAL BINDING PROTEIN
2gj2:C (ALA2) to (CYS46) CRYSTAL STRUCTURE OF VP9 FROM WHITE SPOT SYNDROME VIRUS | FERREDOXIN FOLD, METAL BINDING PROTEIN
2gj2:D (ALA2) to (CYS46) CRYSTAL STRUCTURE OF VP9 FROM WHITE SPOT SYNDROME VIRUS | FERREDOXIN FOLD, METAL BINDING PROTEIN
2gjv:B (GLY48) to (ALA132) CRYSTAL STRUCTURE OF A PROTEIN OF UNKNOWN FUNCTION FROM SALMONELLA TYPHIMURIUM | STRUCTURAL GENOMICS, UNKNOWN FUNCTION, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG
2gjv:C (GLY48) to (ALA132) CRYSTAL STRUCTURE OF A PROTEIN OF UNKNOWN FUNCTION FROM SALMONELLA TYPHIMURIUM | STRUCTURAL GENOMICS, UNKNOWN FUNCTION, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG
2gjv:E (GLY48) to (ALA132) CRYSTAL STRUCTURE OF A PROTEIN OF UNKNOWN FUNCTION FROM SALMONELLA TYPHIMURIUM | STRUCTURAL GENOMICS, UNKNOWN FUNCTION, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG
2gjv:F (GLY48) to (ALA132) CRYSTAL STRUCTURE OF A PROTEIN OF UNKNOWN FUNCTION FROM SALMONELLA TYPHIMURIUM | STRUCTURAL GENOMICS, UNKNOWN FUNCTION, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG
4l53:A (GLY94) to (ILE173) CRYSTAL STRUCTURE OF (1R,4R)-4-{4-[7-AMINO-2-(1,2,3-BENZOTHIADIAZOL-7- YL)-3-CHLOROFURO[2,3-C]PYRIDIN-4-YL]-1H-PYRAZOL-1-YL}CYCLOHEXAN-1-OL BOUND TO TAK1-TAB1 | TAK1 KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4zmf:B (GLY601) to (PRO714) PHOSPHORYLATED ASPARTATE IN THE CRYSTAL STRUCTURE OF THE ALPHA-KINASE DOMAIN OF MYOSIN-II HEAVY CHAIN KINASE A | ASPARTYL PHOSPHATE INTERMEDIATE, TRANSFERASE
4l67:A (THR332) to (MET395) CRYSTAL STRUCTURE OF CATALYTIC DOMAIN OF PAK4 | CATALYTIC DOMAIN OF PAK4, TRANSFERASE
4l68:A (GLY319) to (LYS380) STRUCTURE OF THE PSEDUDOKINASE DOMAIN OF BIR2, AN IMMUNE REGULATOR OF THE RLK/PELLE FAMILY | PSEUDOKINASE, NEGATIVE IMMUNE REGULATOR, SIGNALING PROTEIN
2w0j:A (GLY232) to (VAL300) CRYSTAL STRUCTURE OF CHK2 IN COMPLEX WITH NSC 109555, A SPECIFIC INHIBITOR | CHK2 INHIBITOR, ONCOLOGY, KINASE, STRUCTURE-ASSISTED DRUG DESIGN, TRANSFERASE, NUCLEOTIDE-BINDING, LI-FRAUMENI SYNDROME, SERINE/THREONINE-PROTEIN KINASE
2gpq:A (GLY151) to (VAL217) CAP-FREE STRUCTURE OF EIF4E SUGGESTS BASIS FOR ITS ALLOSTERIC REGULATION | TRANSLATION REGULATION, EIF4E, APO FORM
4zog:A (GLY254) to (GLU316) VX-680/MK-0457 BINDS TO HUMAN ABL1 ALSO IN INACTIVE DFG CONFORMATIONS. | KINASE, TRANSFERASE, ABL1, DFG CONFORMATIONS
4zop:A (LYS776) to (ASN853) CO-CRYSTAL STRUCTURE OF LIPID KINASE PI3K ALPHA WITH A SELECTIVE PHOSPHATIDYLINOSITOL-3 KINASE ALPHA INHIBITOR | LIPID KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ztm:A (GLY198) to (VAL263) IRAK4-INHIBITOR CO-STRUCTURE | KINASE, PHOSPHATASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1th8:A (ASN61) to (HIS137) CRYSTAL STRUCTURES OF THE ADP AND ATP BOUND FORMS OF THE BACILLUS ANTI-SIGMA FACTOR SPOIIAB IN COMPLEX WITH THE ANTI-ANTI-SIGMA SPOIIAA: INHIBITORY COMPLEX WITH ADP, CRYSTAL FORM II | SPOIIAB, SPOIIAA, ANTI-SIGMA, ANTI-ANTI-SIGMA, SPORULATION, SERINE KINASE, TRANSCRIPTION
2w7v:A (ASP343) to (ARG403) PERIPLASMIC DOMAIN OF EPSL FROM VIBRIO PARAHAEMOLYTICUS | TRANSPORT, TYPE II SECRETION, TRANSPORT PROTEIN
2w7v:B (ASP343) to (ARG403) PERIPLASMIC DOMAIN OF EPSL FROM VIBRIO PARAHAEMOLYTICUS | TRANSPORT, TYPE II SECRETION, TRANSPORT PROTEIN
1tid:A (ASN61) to (LYS136) CRYSTAL STRUCTURES OF THE ADP AND ATP BOUND FORMS OF THE BACILLUS ANTI-SIGMA FACTOR SPOIIAB IN COMPLEX WITH THE ANTI-ANTI-SIGMA SPOIIAA: POISED FOR PHOSPHORYLATION COMPLEX WITH ATP, CRYSTAL FORM I | SPOIIAB, SPOIIAA, ANTI-SIGMA, ANTI-ANTI-SIGMA, SPORULATION, SERINE KINASE, TRANSCRIPTION
1tid:C (ASN61) to (LYS135) CRYSTAL STRUCTURES OF THE ADP AND ATP BOUND FORMS OF THE BACILLUS ANTI-SIGMA FACTOR SPOIIAB IN COMPLEX WITH THE ANTI-ANTI-SIGMA SPOIIAA: POISED FOR PHOSPHORYLATION COMPLEX WITH ATP, CRYSTAL FORM I | SPOIIAB, SPOIIAA, ANTI-SIGMA, ANTI-ANTI-SIGMA, SPORULATION, SERINE KINASE, TRANSCRIPTION
3is5:A (GLY147) to (GLU211) CRYSTAL STRUCTURE OF CDPK KINASE DOMAIN FROM TOXOPLASMA GONDII, TGME49_018720 | TOXOPLASMA GONDII, CDPK, STRUCTURAL GENOMICS, PARASITOLOGY, STRUCTURAL GENOMICS CONSORTIUM, SGC, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
2waq:C (SER154) to (ALA211) THE COMPLETE STRUCTURE OF THE ARCHAEAL 13-SUBUNIT DNA- DIRECTED RNA POLYMERASE | MULTI-SUBUNIT, RNA POLYMERASE, TRANSCRIPTION
1tqm:A (SER104) to (MET179) CRYSTAL STRUCTURE OF A. FULGIDUS RIO2 SERINE PROTEIN KINASE BOUND TO AMPPNP | SERINE KINASE, AMPPNP, ANP, RIBOSOME
4zy4:A (GLY282) to (GLU345) CRYSTAL STRUCTURE OF P21 ACTIVATED KINASE 1 IN COMPLEX WITH AN INHIBITOR COMPOUND 4 | KINASE, INHIBITOR, COMPLEX
4zy4:B (GLY282) to (GLU345) CRYSTAL STRUCTURE OF P21 ACTIVATED KINASE 1 IN COMPLEX WITH AN INHIBITOR COMPOUND 4 | KINASE, INHIBITOR, COMPLEX
2wei:A (GLY88) to (GLY152) CRYSTAL STRUCTURE OF THE KINASE DOMAIN OF CRYPTOSPORIDIUM PARVUM CALCIUM DEPENDENT PROTEIN KINASE IN COMPLEX WITH 3- MB-PP1 | NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, KINASE, TRANSFERASE, ATP-BINDING
2wfq:A (ARG122) to (LYS187) CRYSTAL STRUCTURE OF THE N-TERMINAL SIGNALLING DOMAIN OF HUMAN DHH WITHOUT CALCIUM | LIPOPROTEIN, DEVELOPMENT, CELL MEMBRANE, AUTOCATALYTIC CLEAVAGE, SIGNALING PROTEIN, DISEASE MUTATION, HEDGEHOG SIGNALLING, PROTEASE, MEMBRANE, SECRETED, PALMITATE, HYDROLASE, SIGNAL TRANSDUCTION, DEVELOPMENTAL PROTEIN
2wfr:A (ARG122) to (LYS187) CRYSTAL STRUCTURE OF THE N-TERMINAL SIGNALLING DOMAIN OF HUMAN DHH WITH CALCIUM | LIPOPROTEIN, DEVELOPMENT, CELL MEMBRANE, AUTOCATALYTIC CLEAVAGE, SIGNALING PROTEIN, DISEASE MUTATION, HEDGEHOG SIGNALLING, PROTEASE, MEMBRANE, SECRETED, PALMITATE, HYDROLASE, SIGNAL TRANSDUCTION, DEVELOPMENTAL PROTEIN
2wfx:A (LYS122) to (LYS187) CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN HUMAN HEDGEHOG- INTERACTING PROTEIN HIP AND SONIC HEDGEHOG IN THE PRESENCE OF CALCIUM | SIGNALING PROTEIN, AUTOCATALYTIC CLEAVAGE, PROTEASE, MEMBRANE, SECRETED, PALMITATE, HYDROLASE, SIGNAL TRANSDUCTION, DEVELOPMENTAL PROTEIN, LIPOPROTEIN, DEVELOPMENT, GLYCOPROTEIN, CELL MEMBRANE, DISULFIDE BOND, EGF-LIKE DOMAIN, HEDGEHOG SIGNALING
1tu1:A (GLN20) to (GLN92) CRYSTAL STRUCTURE OF PROTEIN OF UNKNOWN FUNCTION PA94 FROM PSEUDOMONAS AERUGINOSA, PUTATIVE REGULATOR | STRUCTURAL GENOMICS, HYPOTHETICAL PROTEIN, PA0094, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
1tu1:B (GLN18) to (GLN92) CRYSTAL STRUCTURE OF PROTEIN OF UNKNOWN FUNCTION PA94 FROM PSEUDOMONAS AERUGINOSA, PUTATIVE REGULATOR | STRUCTURAL GENOMICS, HYPOTHETICAL PROTEIN, PA0094, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
2wg4:A (GLY128) to (LYS187) CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN HUMAN HEDGEHOG- INTERACTING PROTEIN HIP AND SONIC HEDGEHOG WITHOUT CALCIUM | AUTOCATALYTIC CLEAVAGE, PROTEASE, MEMBRANE, SECRETED, PALMITATE, HYDROLASE, SIGNAL TRANSDUCTION, DEVELOPMENTAL PROTEIN, SIGNALING PROTEIN, LIPOPROTEIN, DEVELOPMENT, GLYCOPROTEIN, CELL MEMBRANE, DISULFIDE BOND, EGF-LIKE DOMAIN, HEDGEHOG SIGNALING
3vqv:A (LYS321) to (HIS392) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF PYRROLYSYL-TRNA SYNTHETASE IN COMPLEX WITH AMPPNP (RE-REFINED) | STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, AMINOACYL-TRNA SYNTHETASE, PYRROLYSYL-TRNA SYNTHETASE, AMPPNP, LIGASE
3vqy:A (LYS321) to (MET391) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF PYRROLYSYL-TRNA SYNTHETASE IN COMPLEX WITH BOCLYS AND AMPPNP (FORM 2) | STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, AMINOACYL-TRNA SYNTHETASE, PYRROLYSYL-TRNA SYNTHETASE, AMPPNP, BOCLYS, LIGASE
3vqx:B (LYS321) to (HIS392) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF PYRROLYSYL-TRNA SYNTHETASE IN TRICLINIC CRYSTAL FORM | STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, AMINOACYL-TRNA SYNTHETASE, PYRROLYSYL-TRNA SYNTHETASE, AMP, BOCLYS-AMP, LIGASE
3vqx:C (PRO319) to (MET391) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF PYRROLYSYL-TRNA SYNTHETASE IN TRICLINIC CRYSTAL FORM | STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, AMINOACYL-TRNA SYNTHETASE, PYRROLYSYL-TRNA SYNTHETASE, AMP, BOCLYS-AMP, LIGASE
3vqx:D (LYS321) to (HIS392) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF PYRROLYSYL-TRNA SYNTHETASE IN TRICLINIC CRYSTAL FORM | STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, AMINOACYL-TRNA SYNTHETASE, PYRROLYSYL-TRNA SYNTHETASE, AMP, BOCLYS-AMP, LIGASE
5a0m:A (ASP344) to (PHE404) THE CRYSTAL STRUCTURE OF I-SCEI IN COMPLEX WITH ITS TARGET DNA IN THE PRESENCE OF MN | HYDROLASE-DNA COMPLEX, GENE TARGETING, GENETICS, PROTEIN-DNA INTERACTION, HOMING ENDONUCLEASES
1hxq:A (GLY71) to (SER173) THE STRUCTURE OF NUCLEOTIDYLATED GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE FROM ESCHERICHIA COLI AT 1.86 ANGSTROMS RESOLUTION | METALLOENZYME, NUCLEOTIDYLATED HISTIDINE, REACTION INTERMEDIATE, NUCLEOTIDYLTRANSFERASE
1hxq:B (GLY71) to (SER173) THE STRUCTURE OF NUCLEOTIDYLATED GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE FROM ESCHERICHIA COLI AT 1.86 ANGSTROMS RESOLUTION | METALLOENZYME, NUCLEOTIDYLATED HISTIDINE, REACTION INTERMEDIATE, NUCLEOTIDYLTRANSFERASE
4lq0:A (GLU181) to (SER243) CRYSTAL STRUCTURE OF THE I-LTRWI LAGLIDADG HOMING ENDONUCLEASE BOUND TO TARGET DNA. | LADLIDADG, PROTEIN-DNA COMPLEX, HOMING ENDONUCLEASE, HYDROLASE, HYDROLASE-DNA COMPLEX
4lqy:A (ILE263) to (ALA318) CRYSTAL STRUCTURE OF HUMAN ENPP4 WITH AMP | NPP4, ENPP4, PHOSPHODIESTERASE, HYDROLASE
4lr2:A (ASN231) to (ALA318) CRYSTAL STRUCTURE OF HUMAN ENPP4 (APO) | NPP4, ENPP4, PHOSPHODIESTERASE, HYDROLASE
3vw8:A (GLY1095) to (PRO1158) CRYSTAL STRUCTURE OF HUMAN C-MET KINASE DOMAIN WITH ITS INHIBITOR | TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1u02:A (ARG107) to (ARG155) CRYSTAL STRUCTURE OF TREHALOSE-6-PHOSPHATE PHOSPHATASE RELATED PROTEIN | STRUCTURAL GENOMICS, PHOSPHATASE, PSI, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
1i1q:A (ARG60) to (SER109) STRUCTURE OF THE COOPERATIVE ALLOSTERIC ANTHRANILATE SYNTHASE FROM SALMONELLA TYPHIMURIUM | TRYPTOPHAN BIOSYNTHESIS, LYASE
4lrk:C (ALA155) to (ASN212) BACTERIAL EFFECTOR NLEH2 KINASE DOMAIN | STRUCTURAL GENOMICS, MONTREAL-KINGSTON BACTERIAL STRUCTURAL GENOMICS INITIATIVE, BSGI, KINASE FOLD, BACTERIAL EFFECTOR KINASE, TRANSFERASE
2wmu:A (GLU22) to (PHE83) CRYSTAL STRUCTURE OF CHECKPOINT KINASE 1 (CHK1) IN COMPLEX WITH INHIBITORS | SERINE/THREONINE-PROTEIN KINASE, POLYMORPHISM, PHOSPHOPROTEIN, UBL CONJUGATION, ISOPEPTIDE BOND, CHECKPOINT KINASE, NUCLEOTIDE-BINDING, SERINE/THREONINE KINASE, DNA DAMAGE, DNA REPAIR, ATP-BINDING, TRANSFERASE, CHK1, KINASE, NUCLEUS, CYTOPLASM, CELL CYCLE
1u2v:D (ASP149) to (PRO229) CRYSTAL STRUCTURE OF ARP2/3 COMPLEX WITH BOUND ADP AND CALCIUM | STRUCTURAL PROTEIN
1u55:A (GLY111) to (LYS179) CRYSTAL STRUCTURE OF AN OXYGEN BINDING H-NOX DOMAIN RELATED TO SOLUBLE GUANYLATE CYCLASES (OXYGEN COMPLEX) | H-NOX DOMAIN, HEME, OXYGEN SENSOR, SIGNAL TRANSDUCTION, CHEMOTAXIS, SIGNALING PROTEIN
3iz3:A (ASP160) to (SER223) CRYOEM STRUCTURE OF CYTOPLASMIC POLYHEDROSIS VIRUS | CRYOELECTRON MICROSCOPY, CYTOPLASMIC POLYHEDROSIS VIRUS, REOVIRUS, TRANSCRIPTION, ICOSAHEDRAL VIRUS, VIRUS
1ua2:B (LEU78) to (LEU153) CRYSTAL STRUCTURE OF HUMAN CDK7 | CELL CYCLE; PHOSPHORYLATION; PROTEIN-PROTEIN INTERACTION; PROTEIN KINASE, CELL CYCLE, TRANSFERASE
1ua2:C (LEU78) to (LEU153) CRYSTAL STRUCTURE OF HUMAN CDK7 | CELL CYCLE; PHOSPHORYLATION; PROTEIN-PROTEIN INTERACTION; PROTEIN KINASE, CELL CYCLE, TRANSFERASE
2wtd:A (GLU233) to (VAL300) CRYSTAL STRUCTURE OF CHK2 IN COMPLEX WITH AN INHIBITOR | TRANSFERASE, KINASE, CELL CYCLE, LI-FRAUMENI SYNDROME
2i0k:A (THR264) to (VAL328) CHOLESTEROL OXIDASE FROM BREVIBACTERIUM STEROLICUM- HIS121ALA MUTANT | OXIDOREDUCTASE, MIX ALPHA BETA, COVALENT FAD, FLAVOENZYME
1iji:A (GLU290) to (THR337) CRYSTAL STRUCTURE OF L-HISTIDINOL PHOSPHATE AMINOTRANSFERASE WITH PLP | AMINOTRANSFERASE, HISC, HISTIDINE BIOSYNTHESIS, PYRIDOXAL PHOSPHATE, TRANSFERASE
2i6l:B (LEU33) to (VAL107) CRYSTAL STRUCTURE OF HUMAN MITOGEN ACTIVATED PROTEIN KINASE 6 (MAPK6) | MAPK6, ERK3, MITOGEN ACTIVATED PROTEIN KINASE 6, EXTRACELLULAR SIGNAL REGULATED KINASE 3, SERINE PHOSPHORYLATION, THREONINE PHOSPHORYLATION, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE
1in0:A (GLU36) to (LYS97) YAJQ PROTEIN (HI1034) | ALPHA AND BETA SANDWICH, STRUCTURAL GENOMICS, STRUCTURE 2 FUNCTION PROJECT, S2F, UNKNOWN FUNCTION
1um0:A (ARG9) to (GLN86) CRYSTAL STRUCTURE OF CHORISMATE SYNTHASE COMPLEXED WITH FMN | BETA-ALPHA-BETA SANDWICH FOLD, LYASE
1um0:B (ARG9) to (ALA88) CRYSTAL STRUCTURE OF CHORISMATE SYNTHASE COMPLEXED WITH FMN | BETA-ALPHA-BETA SANDWICH FOLD, LYASE
1um0:D (ARG9) to (ALA88) CRYSTAL STRUCTURE OF CHORISMATE SYNTHASE COMPLEXED WITH FMN | BETA-ALPHA-BETA SANDWICH FOLD, LYASE
1um2:A (ASP501) to (SER551) CRYSTAL STRUCTURE OF THE VMA1-DERIVED ENDONUCLEASE WITH THE LIGATED EXTEIN SEGMENT | PROTEIN SPLICING, VMA1-DERIVED ENDONUCLEASE, VDE, INTEIN, EXTEIN, THIAZOLIDINE, HYDROLASE
1umf:A (ARG9) to (GLN86) CRYSTAL STRUCTURE OF CHORISMATE SYNTHASE | BETA-ALPHA-BETA SANDWICH FOLD, LYASE
1umf:B (ARG9) to (ALA88) CRYSTAL STRUCTURE OF CHORISMATE SYNTHASE | BETA-ALPHA-BETA SANDWICH FOLD, LYASE
1umf:D (ARG9) to (ASN85) CRYSTAL STRUCTURE OF CHORISMATE SYNTHASE | BETA-ALPHA-BETA SANDWICH FOLD, LYASE
2ibg:E (ARG181) to (LYS246) CRYSTAL STRUCTURE OF HEDGEHOG BOUND TO THE FNIII DOMAINS OF IHOG | IHOG, HEDGEHOG, FIBRONECTIN TYPE III, PROTEIN BINDING
2ibg:G (ARG181) to (LYS246) CRYSTAL STRUCTURE OF HEDGEHOG BOUND TO THE FNIII DOMAINS OF IHOG | IHOG, HEDGEHOG, FIBRONECTIN TYPE III, PROTEIN BINDING
3wav:A (ASP381) to (VAL447) CRYSTAL STRUCTURE OF AUTOTAXIN IN COMPLEX WITH COMPOUND 10 | HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3waw:A (ASP381) to (VAL447) CRYSTAL STRUCTURE OF AUTOTAXIN IN COMPLEX WITH 2BOA | HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3wax:A (ASP381) to (VAL447) CRYSTAL STRUCTURE OF AUTOTAXIN IN COMPLEX WITH 3BOA | HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3way:A (ASP381) to (VAL447) CRYSTAL STRUCTURE OF AUTOTAXIN IN COMPLEX WITH 4BOA | HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
2ig7:B (LEU81) to (GLN146) CRYSTAL STRUCTURE OF HUMAN CHOLINE KINASE B | NON-PROTEIN KINASE, CHOLINE KINASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE
1uup:C (LYS3115) to (PHE3184) CRYSTAL STRUCTURE OF A DIMERIC FORM OF STREPTOCOCCAL PYROGENIC EXOTOXIN A (SPEA1). | TOXIN, MOLECULAR RECOGNITION, X-RAY CRYSTALLOGRAPHY, SUPERANTIGEN, EXOTOXIN, ZINC BINDING, DIMER
4md8:G (SER51) to (GLU114) CRYSTAL STRUCTURE OF FULL-LENGTH SYMMETRIC CK2 HOLOENZYME WITH MUTATED ALPHA SUBUNIT (F121E) | PROTEIN SERINE/THREONINE KINASE, TRANSFERASE
4md8:H (SER51) to (GLU114) CRYSTAL STRUCTURE OF FULL-LENGTH SYMMETRIC CK2 HOLOENZYME WITH MUTATED ALPHA SUBUNIT (F121E) | PROTEIN SERINE/THREONINE KINASE, TRANSFERASE
1uwv:A (HIS188) to (VAL242) CRYSTAL STRUCTURE OF RUMA, THE IRON-SULFUR CLUSTER CONTAINING E. COLI 23S RIBOSOMAL RNA 5-METHYLURIDINE METHYLTRANSFERASE | METHYLTRANSFERASE, RNA MODIFICATION, IRON-SULFUR CLUSTER, TRANSFERASE, RNA PROCESSING
3wi6:A (LEU79) to (GLU139) CRYSTAL STRUCTURE OF MAPKAP KINASE-2 (MK2) IN COMPLEX WITH NON- SELECTIVE INHIBITOR | GLY-RICH LOOP FORMED, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3wi6:B (LEU79) to (GLU139) CRYSTAL STRUCTURE OF MAPKAP KINASE-2 (MK2) IN COMPLEX WITH NON- SELECTIVE INHIBITOR | GLY-RICH LOOP FORMED, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3wi6:C (LEU79) to (GLU139) CRYSTAL STRUCTURE OF MAPKAP KINASE-2 (MK2) IN COMPLEX WITH NON- SELECTIVE INHIBITOR | GLY-RICH LOOP FORMED, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3wi6:E (LEU79) to (GLU139) CRYSTAL STRUCTURE OF MAPKAP KINASE-2 (MK2) IN COMPLEX WITH NON- SELECTIVE INHIBITOR | GLY-RICH LOOP FORMED, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3wi6:F (LEU79) to (GLU139) CRYSTAL STRUCTURE OF MAPKAP KINASE-2 (MK2) IN COMPLEX WITH NON- SELECTIVE INHIBITOR | GLY-RICH LOOP FORMED, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
2x4f:A (GLN119) to (GLU181) THE CRYSTAL STRUCTURE OF THE HUMAN MYOSIN LIGHT CHAIN KINASE LOC340156. | LUNG, KINASE, MYOSIN, BREAST CANCER, TRANSFERASE
2x4f:B (GLY118) to (GLU181) THE CRYSTAL STRUCTURE OF THE HUMAN MYOSIN LIGHT CHAIN KINASE LOC340156. | LUNG, KINASE, MYOSIN, BREAST CANCER, TRANSFERASE
1v33:A (VAL75) to (VAL154) CRYSTAL STRUCTURE OF DNA PRIMASE FROM PYROCOCCUS HORIKOSHII | NUCLEOTIDYL TRANSFERASE, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, STRUCTURAL GENOMICS
2x7f:D (TYR40) to (GLU106) CRYSTAL STRUCTURE OF THE KINASE DOMAIN OF HUMAN TRAF2- AND NCK-INTERACTING KINASE WITH WEE1CHK1 INHIBITOR | SERINE/THREONINE-PROTEIN KINASE, PHOSPHOPROTEIN, KINASE, TRANSFERASE
1j6x:A (TYR19) to (LEU89) CRYSTAL STRUCTURE OF HELICOBACTER PYLORI LUXS | ALPHA-BETA FOLD, SIGNALING PROTEIN
1j6x:B (TYR19) to (LEU89) CRYSTAL STRUCTURE OF HELICOBACTER PYLORI LUXS | ALPHA-BETA FOLD, SIGNALING PROTEIN
2x8i:A (GLY21) to (PHE83) DISCOVERY OF A NOVEL CLASS OF TRIAZOLONES AS CHECKPOINT KINASE INHIBITORS - HIT TO LEAD EXPLORATION | NUCLEOTIDE-BINDING, CYTOSKELETON, PHOSPHOPROTEIN, ISOPEPTIDE BOND, CELL CYCLE, TRANSFERASE, DNA DAMAGE, DNA REPAIR
2iwi:B (GLY44) to (LEU116) CRYSTAL STRUCTURE OF THE HUMAN PIM2 IN COMPLEX WITH A RUTHENIUM ORGANOMETALLIC LIGAND RU1 | NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, PIM2, KINASE, CANCER, LEUKEMIA, TRANSFERASE, ATP-BINDING, PROTO- ONCOGENE, PHOSPHORYLATION
5anj:A (GLY16) to (PHE80) CRYSTAL STRUCTURE OF CDK2 IN COMPLEX WITH N-(9H-PURIN-6-YL) THIOPHENE-2-CARBOXAMIDE PROCESSED WITH THE CRYSTALDIRECT AUTOMATED MOUNTING AND CRYO-COOLING TECHNOLOGY | TRANSFERASE, PROTEIN KINASE, INHIBITOR, AUTOMATED CRYSTAL HARVESTING, AUTOMATED CRYO-COOLING, CRYSTALDIRECT
1jg5:B (PRO1) to (ASP50) CRYSTAL STRUCTURE OF RAT GTP CYCLOHYDROLASE I FEEDBACK REGULATORY PROTEIN, GFRP | ALPHA/BETA STRUCTURE, BETA SHEET, PROTEIN BINDING
2j2i:B (GLY50) to (ILE119) CRYSTAL STRUCTURE OF THE HUMAB PIM1 IN COMPLEX WITH LY333531 | TRANSFERASE, NUCLEOTIDE-BINDING, ALTERNATIVE INITIATION, SERINE/THREONINE-PROTEIN KINASE, ATP-BINDING, METAL-BINDING, PROTO-ONCOGENE, KINASE, CANCER, LEUKEMIA, MANGANESE, NUCLEAR PROTEIN, PROTO- ONCOGENE, PHOSPHORYLATION
3wqy:A (CYS837) to (GLN885) CRYSTAL STRUCTURE OF ARCHAEOGLOBUS FULGIDUS ALANYL-TRNA SYNTHETASE IN COMPLEX WITH WILD-TYPE TRNA(ALA) HAVING G3.U70 | AMINOACYL-TRNA SYNTHETASES, PROTEIN-RNA COMPLEX, LIGASE, ALANYLADENYLATE ANALOGUE, LIGASE-RNA COMPLEX
3wqy:B (GLY833) to (ALA883) CRYSTAL STRUCTURE OF ARCHAEOGLOBUS FULGIDUS ALANYL-TRNA SYNTHETASE IN COMPLEX WITH WILD-TYPE TRNA(ALA) HAVING G3.U70 | AMINOACYL-TRNA SYNTHETASES, PROTEIN-RNA COMPLEX, LIGASE, ALANYLADENYLATE ANALOGUE, LIGASE-RNA COMPLEX
5ar5:A (GLY30) to (GLU96) RIP2 KINASE CATALYTIC DOMAIN (1 - 310) COMPLEX WITH BENZIMIDAZOLE | TRANSFERASE, KINASE DOMAIN, KINASE INHIBITOR, STRUCTURE-BASED DRUG DESIGN, INHIBITOR SELECTIVITY
5ar5:B (GLY30) to (GLU96) RIP2 KINASE CATALYTIC DOMAIN (1 - 310) COMPLEX WITH BENZIMIDAZOLE | TRANSFERASE, KINASE DOMAIN, KINASE INHIBITOR, STRUCTURE-BASED DRUG DESIGN, INHIBITOR SELECTIVITY
5ar2:A (GLY30) to (GLU96) RIP2 KINASE CATALYTIC DOMAIN (1 - 310) | TRANSFERASE, KINASE DOMAIN, KINASE INHIBITOR, STRUCTURE-BASED DRUG DESIGN, INHIBITOR SELECTIVITY
5ar2:B (GLY30) to (GLU96) RIP2 KINASE CATALYTIC DOMAIN (1 - 310) | TRANSFERASE, KINASE DOMAIN, KINASE INHIBITOR, STRUCTURE-BASED DRUG DESIGN, INHIBITOR SELECTIVITY
5ar3:A (GLY30) to (GLU96) RIP2 KINASE CATALYTIC DOMAIN (1 - 310) COMPLEX WITH AMP-PCP | TRANSFERASE, KINASE INHIBITOR, STRUCTURE-BASED DRUG DESIGN, INHIBITOR SELECTIVITY
5ar3:B (GLY30) to (GLU96) RIP2 KINASE CATALYTIC DOMAIN (1 - 310) COMPLEX WITH AMP-PCP | TRANSFERASE, KINASE INHIBITOR, STRUCTURE-BASED DRUG DESIGN, INHIBITOR SELECTIVITY
5ar4:A (GLY30) to (GLU96) RIP2 KINASE CATALYTIC DOMAIN (1 - 310) COMPLEX WITH SB-203580 | TRANSFERASE, KINASE DOMAIN, KINASE INHIBITOR, STRUCTURE-BASED DRUG DESIGN, INHIBITOR SELECTIVITY
5ar4:B (GLY30) to (GLU96) RIP2 KINASE CATALYTIC DOMAIN (1 - 310) COMPLEX WITH SB-203580 | TRANSFERASE, KINASE DOMAIN, KINASE INHIBITOR, STRUCTURE-BASED DRUG DESIGN, INHIBITOR SELECTIVITY
2xey:A (GLY21) to (PHE83) CRYSTAL STRUCTURE OF CHECKPOINT KINASE 1 (CHK1) IN COMPLEX WITH INHIBITORS | TRANSFERASE, DNA REPAIR, CELL CYCLE
3wqz:A (GLY836) to (GLN885) CRYSTAL STRUCTURE OF ARCHAEOGLOBUS FULGIDUS ALANYL-TRNA SYNTHETASE IN COMPLEX WITH A TRNA(ALA) VARIANT HAVING A3.U70 | AMINOACYL-TRNA SYNTHETASES, PROTEIN-RNA COMPLEX, HOMODIMER, LIGASE, ALANYLADENYLATE ANALOGUE, LIGASE-RNA COMPLEX
3wqz:B (GLY833) to (GLN885) CRYSTAL STRUCTURE OF ARCHAEOGLOBUS FULGIDUS ALANYL-TRNA SYNTHETASE IN COMPLEX WITH A TRNA(ALA) VARIANT HAVING A3.U70 | AMINOACYL-TRNA SYNTHETASES, PROTEIN-RNA COMPLEX, HOMODIMER, LIGASE, ALANYLADENYLATE ANALOGUE, LIGASE-RNA COMPLEX
5ar7:A (GLY30) to (GLU96) RIP2 KINASE CATALYTIC DOMAIN (1 - 310) COMPLEX WITH BIARYL UREA | TRANSFERASE, KINASE DOMAIN, KINASE INHIBITOR, STRUCTURE-BASED DRUG DESIGN, INHIBITOR SELECTIVITY
5ar7:B (GLY30) to (GLU96) RIP2 KINASE CATALYTIC DOMAIN (1 - 310) COMPLEX WITH BIARYL UREA | TRANSFERASE, KINASE DOMAIN, KINASE INHIBITOR, STRUCTURE-BASED DRUG DESIGN, INHIBITOR SELECTIVITY
5ar8:B (GLY30) to (GLU96) RIP2 KINASE CATALYTIC DOMAIN (1 - 310) COMPLEX WITH BIPHENYLSULFONAMIDE | TRANSFERASE, KINASE DOMAIN, KINASE INHIBITOR, STRUCTURE-BASED DRUG DESIGN, INHIBITOR SELECTIVITY
2j51:A (GLY46) to (GLU109) CRYSTAL STRUCTURE OF HUMAN STE20-LIKE KINASE BOUND TO 5- AMINO-3-((4-(AMINOSULFONYL)PHENYL)AMINO)-N-(2,6- DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDE | TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, ATP-BINDING, PHOSPHORYLATION, MUSCLE DEVELOPMENT, KINASE, APOPTOSIS, GERMINAL CENTRE KINASE, SERINE/THREONINE KINASE 2, NUCLEOTIDE-BINDING
1jnk:A (ASN128) to (ASP207) THE C-JUN N-TERMINAL KINASE (JNK3S) COMPLEXED WITH MGAMP-PNP | TRANSFERASE, JNK3 MAP KINASE, SERINE/THREONINE PROTEIN KINASE
1vkw:A (ASP42) to (PHE103) CRYSTAL STRUCTURE OF A PUTATIVE NITROREDUCTASE (TM1586) FROM THERMOTOGA MARITIMA MSB8 AT 2.00 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI, OXIDOREDUCTASE
1vkw:A (LYS153) to (ILE203) CRYSTAL STRUCTURE OF A PUTATIVE NITROREDUCTASE (TM1586) FROM THERMOTOGA MARITIMA MSB8 AT 2.00 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI, OXIDOREDUCTASE
1vr8:A (LYS62) to (SER112) CRYSTAL STRUCTURE OF GTP BINDING REGULATOR (TM1622) FROM THERMOTOGA MARITIMA AT 1.75 A RESOLUTION | TM1622, GTP BINDING REGULATOR, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI, SIGNALING PROTEIN
2j90:B (ALA25) to (ILE92) CRYSTAL STRUCTURE OF HUMAN ZIP KINASE IN COMPLEX WITH A TETRACYCLIC PYRIDONE INHIBITOR (PYRIDONE 6) | NUCLEAR PROTEIN, NUCLEOTIDE-BINDING, SERINE/THREONINE- PROTEIN KINASE, CHROMATIN REGULATOR, MYOSIN PHOSPHORYLATION, KINASE, MUSCLE, APOPTOSIS, TRANSFERASE, ATP-BINDING
5ax3:A (GLY28) to (ASP97) CRYSTAL STRUCTURE OF ERK2 COMPLEXED WITH ALLOSTERIC AND ATP- COMPETITIVE INHIBITORS. | TERNARY COMPLEX, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2ja5:K (LYS18) to (THR77) CPD LESION CONTAINING RNA POLYMERASE II ELONGATION COMPLEX A | DNA-DIRECTED RNA POLYMERASE, LESION RECOGNITION, TRANSFERASE/DNA/RNA, DNA DAMAGE, ZINC-FINGER, DNA-BINDING, PHOTOLESION, PHOSPHORYLATION, MISINCORPORATION, RNA POLYMERASE II, TRANSCRIPTION- COUPLED REPAIR, CYCLOBUTANE PYRIMIDINE DIMER, TCR, CPD, ZINC, ARREST, STALLING, DNA LESION, METAL-BINDING, NUCLEAR PROTEIN, TRANSCRIPTION BUBBLE, NUCLEOTIDYLTRANSFERASE, DAMAGE RECOGNITION, ELONGATION COMPLEX, TRANSFERASE, THYMINE DIMER, TRANSCRIPTION
2xm9:A (GLU233) to (VAL300) STRUCTURE OF A SMALL MOLECULE INHIBITOR WITH THE KINASE DOMAIN OF CHK2 | TRANSFERASE, CANCER
4myg:A (GLY37) to (PRO108) MAPK13, ACTIVE FORM | P38 KINASE, PHOSPHORYLATION, TRANSFERASE
1jva:A (ASP609) to (GLY670) CRYSTAL STRUCTURE OF THE VMA1-DERIVED ENDONUCLEASE BEARING THE N AND C EXTEIN PROPEPTIDES | PROTEIN-SPLICING, VMA1-DERIVED ENDONUCLEASE, INTEIN, THIAZOLIDINE INTERMEDIATE, VDE, HYDROLASE
1jva:B (ASP609) to (GLY670) CRYSTAL STRUCTURE OF THE VMA1-DERIVED ENDONUCLEASE BEARING THE N AND C EXTEIN PROPEPTIDES | PROTEIN-SPLICING, VMA1-DERIVED ENDONUCLEASE, INTEIN, THIAZOLIDINE INTERMEDIATE, VDE, HYDROLASE
2ja8:K (LYS18) to (THR77) CPD LESION CONTAINING RNA POLYMERASE II ELONGATION COMPLEX D | DNA-DIRECTED RNA POLYMERASE, LESION RECOGNITION, TRANSFERASE/DNA/RNA, DNA DAMAGE, ZINC-FINGER, DNA-BINDING, PHOTOLESION, PHOSPHORYLATION, MISINCORPORATION, RNA POLYMERASE II, TRANSCRIPTION-COUPLED REPAIR, CYCLOBUTANE PYRIMIDINE DIMER TCR, CPD, ARREST, STALLING, DNA LESION, METAL-BINDING, NUCLEAR PROTEIN, TRANSCRIPTION BUBBLE, NUCLEOTIDYLTRANSFERASE, DAMAGE RECOGNITION, ELONGATION COMPLEX, TRANSFERASE, THYMINE DIMER, TRANSCRIPTION
5b0u:A (VAL38) to (HIS93) CRYSTAL STRUCTURE OF THE MUTATED 19 KDA PROTEIN OF OPLOPHORUS LUCIFERASE (NANOKAZ) | OPLOPHORUS LUCIFERASE, LUMINESCENT PROTEIN
5b0u:B (SER37) to (GLY95) CRYSTAL STRUCTURE OF THE MUTATED 19 KDA PROTEIN OF OPLOPHORUS LUCIFERASE (NANOKAZ) | OPLOPHORUS LUCIFERASE, LUMINESCENT PROTEIN
1w2d:A (SER197) to (GLN249) HUMAN INOSITOL (1,4,5)-TRISPHOSPHATE 3-KINASE COMPLEXED WITH MN2+/ADP/INS(1,3,4,5)P4 | INOSITOL PHOSPHATE KINASE, ADP, IP4, TRANSFERASE
1w2d:B (SER197) to (GLN249) HUMAN INOSITOL (1,4,5)-TRISPHOSPHATE 3-KINASE COMPLEXED WITH MN2+/ADP/INS(1,3,4,5)P4 | INOSITOL PHOSPHATE KINASE, ADP, IP4, TRANSFERASE
2xr9:A (ASP381) to (VAL447) CRYSTAL STRUCTURE OF AUTOTAXIN (ENPP2) | HYDROLASE, LYSOPHOSPHATIDYLCHOLINE, SOMATOMEDIN, INFLAMMATION, METASTASIS, NEUROPATHIC PAIN, VASCULAR DEVELOPMENT, NEURAL DEVELOPMENT
5b3q:A (PRO16) to (SER76) NQO5 OF THE TRYPSIN-RESISTANT FRAGMENT (1-134) IN P63 FORM | NADH-UBIQUINONE OXIDOREDUCTASE, COMPLEX I, OXIDOREDUCTASE
5b7w:A (LYS38) to (GLN98) CRYSTAL STRUCTURE OF THE YAJQ-FAMILY PROTEIN XC_3703 FROM XANTHOMONAS CAMPESTRIS PV.CAMPESTRIS | RECEPTOR, UNKNOWN FUNCTION
5b7w:B (GLU36) to (GLY99) CRYSTAL STRUCTURE OF THE YAJQ-FAMILY PROTEIN XC_3703 FROM XANTHOMONAS CAMPESTRIS PV.CAMPESTRIS | RECEPTOR, UNKNOWN FUNCTION
2jfl:A (GLY46) to (GLU109) CRYSTAL STRUCTURE OF HUMAN STE20-LIKE KINASE ( DIPHOSPHORYLATED FORM) BOUND TO 5- AMINO-3-((4-( AMINOSULFONYL)PHENYL)AMINO)-N-(2,6- DIFLUOROPHENYL)-1H-1,2, 4-TRIAZOLE-1-CARBOTHIOAMIDE | TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, ATP-BINDING, PHOSPHORYLATION, MUSCLE DEVELOPMENT, KINASE, APOPTOSIS, GERMINAL CENTRE KINASE, SERINE- THREONINE KINASE 2, NUCLEOTIDE-BINDING, SERINE-THREONINE-PROTEIN KINASE
5bq9:B (THR3) to (GLU57) CRYSTAL STRUCTURE OF UNCHARACTERIZED PROTEIN LPG1496 LEGIONELLA PNEUMOPHILA SUBSP. PNEUMOPHILA | STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
5bq9:B (GLY67) to (PHE111) CRYSTAL STRUCTURE OF UNCHARACTERIZED PROTEIN LPG1496 LEGIONELLA PNEUMOPHILA SUBSP. PNEUMOPHILA | STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, UNKNOWN FUNCTION
2xwg:A (ALA156) to (GLY206) CRYSTAL STRUCTURE OF SORTASE C-1 FROM ACTINOMYCES ORIS (FORMERLY ACTINOMYCES NAESLUNDII) | HYDROLASE, FIMBRIAL ASSEMBLY
2xwg:B (ALA156) to (GLY206) CRYSTAL STRUCTURE OF SORTASE C-1 FROM ACTINOMYCES ORIS (FORMERLY ACTINOMYCES NAESLUNDII) | HYDROLASE, FIMBRIAL ASSEMBLY
2xwg:C (ALA156) to (GLY206) CRYSTAL STRUCTURE OF SORTASE C-1 FROM ACTINOMYCES ORIS (FORMERLY ACTINOMYCES NAESLUNDII) | HYDROLASE, FIMBRIAL ASSEMBLY
2xwg:D (ALA156) to (HIS204) CRYSTAL STRUCTURE OF SORTASE C-1 FROM ACTINOMYCES ORIS (FORMERLY ACTINOMYCES NAESLUNDII) | HYDROLASE, FIMBRIAL ASSEMBLY
2xwg:E (ALA156) to (GLY206) CRYSTAL STRUCTURE OF SORTASE C-1 FROM ACTINOMYCES ORIS (FORMERLY ACTINOMYCES NAESLUNDII) | HYDROLASE, FIMBRIAL ASSEMBLY
3zhp:C (PHE35) to (ILE98) HUMAN MST3 (STK24) IN COMPLEX WITH MO25BETA | CELL CYCLE, MO25,
3zhp:D (PHE35) to (ILE98) HUMAN MST3 (STK24) IN COMPLEX WITH MO25BETA | CELL CYCLE, MO25,
1k23:B (ASP248) to (LYS290) INORGANIC PYROPHOSPHATASE (FAMILY II) FROM BACILLUS SUBTILIS | INORGANIC PYROPHOSPHATASE, MANGANESE, BINUCLEAR METAL CENTRE, HYDROLASE
2jje:A (ASP381) to (PRO426) CRYSTAL STRUCTURE OF T330S MUTANT OF RV3290C FROM M. TUBERCULOSIS | AMINOTRANSFERASE, PYRIDOXAL PHOSPHATE, PLP, RV3290C, TRANSFERASE, T330S MUTANT, LYSINE AMINO TRANSFERASE, MYCOBACTERIUM TUBERCULOSIS
2jjf:A (ASP381) to (PRO426) N328A MUTANT OF M. TUBERCULOSIS RV3290C | PLP, RV3290C, TRANSFERASE, N328A MUTANT, AMINOTRANSFERASE, PYRIDOXAL PHOSPHATE, LYSINE AMINO TRANSFERASE, MYCOBACTERIUM TUBERCULOSIS
5btw:A (LYS4) to (GLU57) STRUCTURE OF THE N-TERMINAL DOMAIN OF LPG1496 FROM LEGIONELLA PNEUMOPHILA | BACTERIAL EFFECTOR, ALPHA-BETA FOLD, NUCLEOTIDE-BINDING, STRUCTURAL GENOMICS, MONTREAL-KINGSTON BACTERIAL STRUCTURAL GENOMICS INITIATIVE, BSGI, UNKNOWN FUNCTION
5btw:B (THR3) to (GLU57) STRUCTURE OF THE N-TERMINAL DOMAIN OF LPG1496 FROM LEGIONELLA PNEUMOPHILA | BACTERIAL EFFECTOR, ALPHA-BETA FOLD, NUCLEOTIDE-BINDING, STRUCTURAL GENOMICS, MONTREAL-KINGSTON BACTERIAL STRUCTURAL GENOMICS INITIATIVE, BSGI, UNKNOWN FUNCTION
5btx:A (LYS4) to (GLU57) STRUCTURE OF THE N-TERMINAL DOMAIN OF LPG1496 FROM LEGIONELLA PNEUMOPHILA IN COMPLEX WITH NUCLEOTIDE | BACTERIAL EFFECTOR, ALPHA-BETA FOLD, NUCLEOTIDE-BINDING, COMPLEX, STRUCTURAL GENOMICS, MONTREAL-KINGSTON BACTERIAL STRUCTURAL GENOMICS INITIATIVE, BSGI, UNKNOWN FUNCTION
5btx:B (THR3) to (GLU57) STRUCTURE OF THE N-TERMINAL DOMAIN OF LPG1496 FROM LEGIONELLA PNEUMOPHILA IN COMPLEX WITH NUCLEOTIDE | BACTERIAL EFFECTOR, ALPHA-BETA FOLD, NUCLEOTIDE-BINDING, COMPLEX, STRUCTURAL GENOMICS, MONTREAL-KINGSTON BACTERIAL STRUCTURAL GENOMICS INITIATIVE, BSGI, UNKNOWN FUNCTION
5bty:A (SER156) to (LYS214) STRUCTURE OF THE MIDDLE DOMAIN OF LPG1496 FROM LEGIONELLA PNEUMOPHILA IN P21 SPACE GROUP | BACTERIAL EFFECTOR, ALPHA-BETA FOLD, NUCLEOTIDE BINDING, STRUCTURAL GENOMICS, MONTREAL-KINGSTON BACTERIAL STRUCTURAL GENOMICS INITIATIVE, BSGI, UNKNOWN FUNCTION
5btz:A (SER156) to (TYR218) STRUCTURE OF THE MIDDLE DOMAIN OF LPG1496 FROM LEGIONELLA PNEUMOPHILA IN P212121 SPACE GROUP | BACTERIAL EFFECTOR, ALPHA-BETA FOLD, NUCLEOTIDE-BINDING, STRUCTURAL GENOMICS, MONTREAL-KINGSTON BACTERIAL STRUCTURAL GENOMICS INITIATIVE, BSGI, UNKNOWN FUNCTION
2joe:A (GLU18) to (ASP87) NMR STRUCTURE OF E. COLI YEHR PROTEIN. NORTHEAST STRUCTURAL GENOMICS TARGET ER538. | SIX ANTIPARALLEL BETA STRANDS, ALPHA + BETA SANDWICH, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, UNKNOWN FUNCTION
1k83:K (LYS18) to (THR77) CRYSTAL STRUCTURE OF YEAST RNA POLYMERASE II COMPLEXED WITH THE INHIBITOR ALPHA AMANITIN | TRANSCRIPTION-TOXIN COMPLEX, ALPHA AMANITIN, TOXIN, INHIBITOR, POLYMERASE, TRANSFERASE, DNA BINDING, ZINC-FINGER, PHOSPHOPROTEIN, TRANSCRIPTION, UBL TRANSCRIPTION-TOXIN COMPLEX
1k8k:D (ASP149) to (PRO229) CRYSTAL STRUCTURE OF ARP2/3 COMPLEX | BETA-PROPELLER, STRUCTURAL PROTEIN
3jaz:A (ASP160) to (TYR221) ATOMIC MODEL OF CYTOPLASMIC POLYHEDROSIS VIRUS WITH ATP | VIRAL ATPASE, HISTIDINE-MEDIATED GUANYLYL TRANSFER, CONFORMATIONAL CHANGES, REGULATION OF TRANSCRIPTION, VIRUS
3jb0:A (ASP160) to (TYR221) ATOMIC MODEL OF CYTOPLASMIC POLYHEDROSIS VIRUS WITH GTP | VIRAL ATPASE, HISTIDINE-MEDIATED GUANYLYL TRANSFER, CONFORMATIONAL CHANGES, REGULATION OF TRANSCRIPTION, VIRUS
2kfp:A (MET44) to (ASN97) SOLUTION NMR STRUCTURE OF PSPTO_3016 FROM PSEUDOMONAS SYRINGAE. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET PSR293. | ALPHA, BETA, DOUBLE-WING, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, UNKNOWN FUNCTION
4njx:C (CYS75) to (LEU153) HUMAN HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2 (HHINT2) IN P41212 SPACE GROUP AT 2.83 A | HINT, HISTIDINE TRIAD, HIT, PHOSPHORAMIDASE, HYDROLASE, DNA BINDING PROTEIN
4njx:D (CYS75) to (LEU153) HUMAN HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2 (HHINT2) IN P41212 SPACE GROUP AT 2.83 A | HINT, HISTIDINE TRIAD, HIT, PHOSPHORAMIDASE, HYDROLASE, DNA BINDING PROTEIN
3jb2:A (ASP160) to (TYR221) ATOMIC MODEL OF CYTOPLASMIC POLYHEDROSIS VIRUS WITH SAM AND GTP | VIRAL ATPASE, HISTIDINE-MEDIATED GUANYLYL TRANSFER, CONFORMATIONAL CHANGES, REGULATION OF TRANSCRIPTION, VIRUS
2kil:A (HIS117) to (LEU178) NMR STRUCTURE OF THE H103G MUTANT SO2144 H-NOX DOMAIN FROM SHEWANELLA ONEIDENSIS IN THE FE(II)CO LIGATION STATE | H-NOX, UNKNOWN FUNCTION
3jb3:A (ASP160) to (TYR221) ATOMIC MODEL OF CYTOPLASMIC POLYHEDROSIS VIRUS WITH SAM, GTP AND ATP | VIRAL ATPASE, HISTIDINE-MEDIATED GUANYLYL TRANSFER, CONFORMATIONAL CHANGES, REGULATION OF TRANSCRIPTION, VIRUS
3zm9:A (LEU124) to (GLN207) THE MECHANISM OF ALLOSTERIC COUPLING IN CHOLINE KINASE A1 REVEALED BY A RATIONALLY DESIGNED INHIBITOR | TRANSFERASE, NEGATIVE COOPERATIVITY, ALLOSTERIC MECHANISM, ELASTIC NETWORK ANALYSIS
3zm9:B (LEU124) to (GLN207) THE MECHANISM OF ALLOSTERIC COUPLING IN CHOLINE KINASE A1 REVEALED BY A RATIONALLY DESIGNED INHIBITOR | TRANSFERASE, NEGATIVE COOPERATIVITY, ALLOSTERIC MECHANISM, ELASTIC NETWORK ANALYSIS
2ycr:A (GLY232) to (VAL300) CRYSTAL STRUCTURE OF CHECKPOINT KINASE 2 IN COMPLEX WITH INHIBITOR PV976 | TRANSFERASE, ANTICANCER DRUG DESIGN
2ycs:A (GLY232) to (VAL300) CRYSTAL STRUCTURE OF CHECKPOINT KINASE 2 IN COMPLEX WITH PV788 | TRANSFERASE, ANTICANCER DRUG DESIGN
2ydk:A (GLN24) to (PHE83) DISCOVERY OF CHECKPOINT KINASE INHIBITOR AZD7762 BY STRUCTURE BASED DESIGN AND OPTIMIZATION OF THIOPHENE CARBOXAMIDE UREAS | TRANSFERASE
3jcl:A (SER635) to (ASN685) CRYO-ELECTRON MICROSCOPY STRUCTURE OF A CORONAVIRUS SPIKE GLYCOPROTEIN TRIMER | CORONAVIRUS, VIRAL FUSION PROTEINS, VIRAL SPIKE, PEPLOMER, VIRAL PROTEIN
3jcl:B (SER635) to (ASN685) CRYO-ELECTRON MICROSCOPY STRUCTURE OF A CORONAVIRUS SPIKE GLYCOPROTEIN TRIMER | CORONAVIRUS, VIRAL FUSION PROTEINS, VIRAL SPIKE, PEPLOMER, VIRAL PROTEIN
3jcl:C (SER635) to (ASN685) CRYO-ELECTRON MICROSCOPY STRUCTURE OF A CORONAVIRUS SPIKE GLYCOPROTEIN TRIMER | CORONAVIRUS, VIRAL FUSION PROTEINS, VIRAL SPIKE, PEPLOMER, VIRAL PROTEIN
3zxt:C (PHE24) to (GLU94) DIMERIC STRUCTURE OF DAPK-1 CATALYTIC DOMAIN IN COMPLEX WITH AMPPCP-MG | APOPTOSIS, TRANSFERASE, ATP BINDING
5c93:A (VAL525) to (PRO608) HISTIDINE KINASE WITH ATP | HISTIDINE KINASE, ATP, TRANSFERASE
2nov:D (GLY232) to (ILE300) BREAKAGE-REUNION DOMAIN OF S.PNEUMONIAE TOPO IV: CRYSTAL STRUCTURE OF A GRAM-POSITIVE QUINOLONE TARGET | PROTEIN, PARC, TOPO IV, GRAM-POSITIVE BACTERIA, QUINOLONE TARGET, DNA BINDING, DNA CLEAVAGE, ISOMERASE
1l0o:A (ASN61) to (SER141) CRYSTAL STRUCTURE OF THE BACILLUS STEAROTHERMOPHILUS ANTI- SIGMA FACTOR SPOIIAB WITH THE SPORULATION SIGMA FACTOR SIGMAF | BERGERAT FOLD, HELIX-TURN-HELIX, PROTEIN BINDING
1l0o:B (VAL64) to (SER141) CRYSTAL STRUCTURE OF THE BACILLUS STEAROTHERMOPHILUS ANTI- SIGMA FACTOR SPOIIAB WITH THE SPORULATION SIGMA FACTOR SIGMAF | BERGERAT FOLD, HELIX-TURN-HELIX, PROTEIN BINDING
2yiq:A (GLY232) to (VAL300) STRUCTURAL ANALYSIS OF CHECKPOINT KINASE 2 IN COMPLEX WITH INHIBITOR PV1322 | TRANSFERASE
3jst:B (GLY20) to (THR75) CRYSTAL STRUCTURE OF TRANSCRIPTIONAL COACTIVATOR/PTERIN DEHYDRATASE FROM BRUCELLA MELITENSIS | LYASE, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID
2ymv:A (PRO30) to (PRO103) STRUCTURE OF REDUCED M SMEGMATIS 5246, A HOMOLOGUE OF M. TUBERCULOSIS ACG | OXIDOREDUCTASE, DORMANCY, REDUCED FMN
5cdm:A (ARG246) to (ARG309) 2.5A STRUCTURE OF QPT-1 WITH S.AUREUS DNA GYRASE AND DNA | TYPE IIA TOPOISOMERASE, ANTIBACTERIAL, INHIBITOR, ISOMERASE
3jvs:A (GLU22) to (PHE83) CHARACTERIZATION OF THE CHK1 ALLOSTERIC INHIBITOR BINDING SITE | PROTEIN KINASE, ATP-BINDING, CELL CYCLE, CYTOPLASM, DNA DAMAGE, DNA REPAIR, ISOPEPTIDE BOND, KINASE, NUCLEOTIDE- BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, UBL CONJUGATION
4o96:A (ALA155) to (ASN212) 2.60 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF A PROTEIN KINASE DOMAIN OF TYPE III EFFECTOR NLEH2 (ECS1814) FROM ESCHERICHIA COLI O157:H7 STR. SAKAI | TYPE III EFFECTOR PROTEIN KINASE, NLEH2, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, PROTEIN KINASE FOLD WITH N-LOBE AND C-LOBE, HYDROLASE
4o96:B (ALA155) to (ASN212) 2.60 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF A PROTEIN KINASE DOMAIN OF TYPE III EFFECTOR NLEH2 (ECS1814) FROM ESCHERICHIA COLI O157:H7 STR. SAKAI | TYPE III EFFECTOR PROTEIN KINASE, NLEH2, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, PROTEIN KINASE FOLD WITH N-LOBE AND C-LOBE, HYDROLASE
4o96:C (ALA155) to (ASN212) 2.60 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF A PROTEIN KINASE DOMAIN OF TYPE III EFFECTOR NLEH2 (ECS1814) FROM ESCHERICHIA COLI O157:H7 STR. SAKAI | TYPE III EFFECTOR PROTEIN KINASE, NLEH2, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, PROTEIN KINASE FOLD WITH N-LOBE AND C-LOBE, HYDROLASE
4o96:D (ALA155) to (ASN212) 2.60 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF A PROTEIN KINASE DOMAIN OF TYPE III EFFECTOR NLEH2 (ECS1814) FROM ESCHERICHIA COLI O157:H7 STR. SAKAI | TYPE III EFFECTOR PROTEIN KINASE, NLEH2, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, PROTEIN KINASE FOLD WITH N-LOBE AND C-LOBE, HYDROLASE
4obp:B (GLN38) to (GLU106) MAP4K4 IN COMPLEX WITH INHIBITOR (COMPOUND 29), 6-(2-FLUOROPYRIDIN-4- YL)PYRIDO[3,2-D]PYRIMIDIN-4-AMINE | KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4oc9:K (LYS313) to (LEU407) 2.35 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF PUTATIVE O- ACETYLHOMOSERINE (THIOL)-LYASE (METY) FROM CAMPYLOBACTER JEJUNI SUBSP. JEJUNI NCTC 11168 WITH N'-PYRIDOXYL-LYSINE-5'-MONOPHOSPHATE AT POSITION 205 | O-ACETYLHOMOSERINE (THIOL)-LYASE, PLP-DEPENDENT ENZYMES, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, LYASE
5cj9:A (VAL85) to (ILE131) BACILLUS HALODURANS ARGININE REPRESSOR, ARGR | STRUCTURAL ANALYSIS, ARGR, TRANSCRIPTIONAL REGULATOR, TRANSCRIPTION REGULATOR
4oej:A (LYS226) to (VAL294) STRUCTURE OF MEMBRANE BINDING PROTEIN PLEUROTOLYSIN B FROM PLEUROTUS OSTREATUS | MACPF DOMAIN, PORE FORMATION, PLEUROTOLYSIN A, MEMBRANE BINDING PROTEIN
4oet:A (LYS52) to (PHE123) CRYSTAL STRUCTURE OF NIKZ FROM CAMPYLOBACTER JEJUNI, UNLIGANDED FORM | EXTRACYTOPLASMIC, NICKEL IMPORT, METAL TRANSPORT, ABC-TYPE IMPORTER, EXTRACYTOPLASMIC NICKEL-BINDING PROTEIN, TRANSPORT PROTEIN
4oet:B (LYS52) to (THR121) CRYSTAL STRUCTURE OF NIKZ FROM CAMPYLOBACTER JEJUNI, UNLIGANDED FORM | EXTRACYTOPLASMIC, NICKEL IMPORT, METAL TRANSPORT, ABC-TYPE IMPORTER, EXTRACYTOPLASMIC NICKEL-BINDING PROTEIN, TRANSPORT PROTEIN
4a3e:K (LYS18) to (THR78) RNA POLYMERASE II INITIAL TRANSCRIBING COMPLEX WITH A 5NT DNA-RNA HYBRID AND SOAKED WITH AMPCPP | TRANSCRIPTION, TRANSCRIPTION INITIATION
4ofz:A (GLY330) to (SER392) STRUCTURE OF UNLIGANDED TREHALOSE-6-PHOSPHATE PHOSPHATASE FROM BRUGIA MALAYI | HAD SUPERFAMILY/ROSSMANN FOLD, TREHALOSE-6-PHOSPHATE PHOSPHOHYDROLASE, HYDROLASE
4a3g:K (LYS18) to (THR78) RNA POLYMERASE II INITIAL TRANSCRIBING COMPLEX WITH A 2NT DNA-RNA HYBRID | TRANSCRIPTION, TRANSCRIPTION INITIATION
5clp:A (GLU55) to (GLU114) CRYSTAL STRUCTURE OF CK2ALPHA WITH 3,4-DICHLOROPHENETHYLAMINE BOUND | TRANSFERASE, CK2ALPHA, CK2A, FRAGMENT BASED DRUG DISCOVERY, HIGH CONCENTRATION SCREENING, SELECTIVE ATP COMPETITIVE INHIBITORS, SURFACE ENTROPHY REDUCTION
2o0g:B (GLN114) to (GLU182) CRYSTAL STRUCTURE OF THE H-NOX DOMAIN FROM NOSTOC SP. PCC 7120 COMPLEXED TO CO | HEME, NO, CO, GUANYLYL CYCLASE, SIGNALING PROTEIN
4oh4:B (GLY895) to (GLU957) CRYSTAL STRUCTURE OF BRI1 IN COMPLEX WITH BKI1 | KINASE DOMAIN, TRANSFERASE, ATP BINDING, PHOSPHORYLATION, MEMBRANE, TRANSFERASE-SIGNALING PROTEIN COMPLEX
2o11:A (ARG3) to (GLY78) MYCOBACTERIUM TUBERCULOSIS CHORISMATE SYNTHASE | SHIKIMATE PATHWAY, M. TUBERCULOSIS, CHORISMATE SYNTHASE, LYASE
2z7l:A (GLY37) to (ASP106) UNPHOSPHORYLATED MITOGEN ACTIVATED PROTEIN KINASE ERK2 IN COMPLEX WITH (4-{[5-CARBAMOYL-4-(3-METHYLANILINO)PYRIMIDIN 2-YL]AMINO}PHENYL)ACETIC ACID | TRANSFERASE, SERINE/THREONINE-PROTEIN KINASE, ATP-BINDING, CELL CYCLE, PHOSPHORYLATION, ACETYLATION, NUCLEOTIDE-BINDING
4a3m:K (LYS18) to (THR78) RNA POLYMERASE II INITIAL TRANSCRIBING COMPLEX WITH A 4NT DNA-RNA HYBRID AND SOAKED WITH AMPCPP | TRANSCRIPTION, TRANSCRIPTION INITIATION
5cs2:A (SER41) to (PRO120) CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM DIADENOSINE TRIPHOSPHATE HYDROLASE IN COMPLEX WITH CYCLOMARIN A | CYCLOMARIN A, DIADENOSINE TRIPHOSPHATE HYDROLASE, ANTI-PLASMODIAL ACTIVITY, MALARIA, PLASMODIUM FALCIPARUM, HYDROLASE
4a6u:A (ASP372) to (PRO426) CRYSTAL STRUCTURE OF THE OMEGA TRANSAMINASE FROM CHROMOBACTERIUM VIOLACEUM IN THE APO FORM, CRYSTALLISED FROM PEG 3350 | TRANSFERASE, PLP-BINDING ENZYME, TRANSAMINASE FOLD TYPE I
3k7b:B (GLY102) to (LYS182) THE STRUCTURE OF THE POXVIRUS A33 PROTEIN REVEALS A DIMER OF UNIQUE C- TYPE LECTIN-LIKE DOMAINS. | C-TYPE LECTIN-LIKE DOMAIN, HOMODIMER, POXVIRUS, EEV, EV, VIRAL PROTEIN
3k7g:B (LYS126) to (LYS191) CRYSTAL STRUCTURE OF THE INDIAN HEDGEHOG N-TERMINAL SIGNALLING DOMAIN | ALPHA+BETA SANDWICH, AUTOCATALYTIC CLEAVAGE, CELL MEMBRANE, DEVELOPMENTAL PROTEIN, DISEASE MUTATION, GLYCOPROTEIN, HYDROLASE, LIPOPROTEIN, MEMBRANE, PALMITATE, PROTEASE, SECRETED, SIGNALING PROTEIN
2zce:A (LYS321) to (MET391) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF PYRROLYSYL-TRNA SYNTHETASE IN COMPLEX WITH PYRROLYSINE AND AN ATP ANALOGUE | AMINOACYL-TRNA SYNTHETASE, PYRROLYSYL-TRNA SYNTHETASE, TRNA, PYRROLYSINE, PROTEIN3000, ATP-BINDING, LIGASE, NUCLEOTIDE-BINDING, PROTEIN BIOSYNTHESIS, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
3k8j:A (GLY212) to (ASP265) STRUCTURE OF CRYSTAL FORM III OF TP0453 | TREPONEMA PALLIDUM, TP0453, OUTER MEMBRANE PROTEIN, MEMBRANE PROTEIN
1xpi:B (LEU96) to (LYS156) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF E. COLI PSEUDOURIDINE SYNTHASE RLUC | PSEUDOURIDINE SYNTHASE, RLUC, CATALYTIC DOMAIN, LYASE
2zfz:B (SER107) to (VAL152) CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN HEXAMER OF ARGR FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH ARGININE | L-ARGININE REPRESSOR, DNA BINDING PROTEIN, CORE, OLIGOMERIZATION DOMAIN, ALPHA/BETA TOPOLOGY, STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, AMINO-ACID BIOSYNTHESIS, ARGININE BIOSYNTHESIS, DNA-BINDING, TRANSCRIPTION, TRANSCRIPTION REGULATION
2zfz:D (SER107) to (VAL152) CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN HEXAMER OF ARGR FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH ARGININE | L-ARGININE REPRESSOR, DNA BINDING PROTEIN, CORE, OLIGOMERIZATION DOMAIN, ALPHA/BETA TOPOLOGY, STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, AMINO-ACID BIOSYNTHESIS, ARGININE BIOSYNTHESIS, DNA-BINDING, TRANSCRIPTION, TRANSCRIPTION REGULATION
2zfz:F (SER107) to (VAL152) CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN HEXAMER OF ARGR FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH ARGININE | L-ARGININE REPRESSOR, DNA BINDING PROTEIN, CORE, OLIGOMERIZATION DOMAIN, ALPHA/BETA TOPOLOGY, STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, AMINO-ACID BIOSYNTHESIS, ARGININE BIOSYNTHESIS, DNA-BINDING, TRANSCRIPTION, TRANSCRIPTION REGULATION
4ona:A (GLY63) to (GLU129) CALCIUM-DEPENDENT PROTEIN KINASE 1 FROM TOXOPLASMA GONDII (TGCDPK1) IN COMPLEX WITH INHIBITOR UW1517 | SERINE/THREONINE PROTEIN KINASE, TRANSFERASE, CALCIUM-BINDING, ATP- BINDING, BUMPED KINASE INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5csw:A (THR470) to (GLN530) B-RAF IN COMPLEX WITH DABRAFENIB | KINASE, PROTEROS BIOSTRUCTURES GMBH, TRANSFERASE
5csw:B (THR470) to (GLN530) B-RAF IN COMPLEX WITH DABRAFENIB | KINASE, PROTEROS BIOSTRUCTURES GMBH, TRANSFERASE
5ct0:B (SER51) to (GLU114) CRYSTAL STRUCTURE OF CK2ALPHA WITH 3-(3-CHLORO-4-(PHENYL)BENZYLAMINO) PROPAN-1-OL BOUND | CK2ALPHA, CK2A, FRAGMENT BASED DRUG DISCOVERY, HIGH CONCENTRATION SCREENING, SELECTIVE ATP COMPETITIVE INHIBITORS, SURFACE ENTROPHY REDUCTION, TRANSFERASE
2zim:A (LYS321) to (HIS392) PYRROLYSYL-TRNA SYNTHETASE BOUND TO ADENYLATED PYRROLYSINE AND PYROPHOSPHATE | TRNA SYNTHETASE BOUND TO AN ADENYLATED INTERMEDIATE, AMINOACYL-TRNA SYNTHETASE, ATP-BINDING, LIGASE, NUCLEOTIDE-BINDING, PROTEIN BIOSYNTHESIS
2zin:A (LYS321) to (MET391) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF PYRROLYSYL- TRNA SYNTHETASE IN COMPLEX WITH BOCLYS AND AN ATP ANALOGUE | AMINOACYL-TRNA SYNTHETASE, PYRROLYSYL-TRNA SYNTHETASE, PYRROLYSINE, TRNA, ATP ANALOGUE, NON-NATURAL AMINO ACID, UNNATURAL AMINO ACID, ATP-BINDING, CYTOPLASM, LIGASE, NUCLEOTIDE-BINDING, PROTEIN BIOSYNTHESIS, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
2zio:A (LYS321) to (HIS392) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF PYRROLYSYL- TRNA SYNTHETASE IN COMPLEX WITH ALOCLYS-AMP AND PNP | AMINOACYL-TRNA SYNTHETASE, PYRROLYSYL-TRNA SYNTHETASE, TRNA, PYRROLYSINE, ATP ANALOGUE, NON-NATURAL AMINO ACID, UNNATURAL AMINO ACID, ATP-BINDING, CYTOPLASM, LIGASE, NUCLEOTIDE-BINDING, PROTEIN BIOSYNTHESIS, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
4oo3:A (LEU352) to (PRO412) CRYSTAL STRUCTURE OF A PUTATIVE OXIDOREDUCTASE (PARMER_00841) FROM PARABACTEROIDES MERDAE ATCC 43184 AT 2.23 A RESOLUTION | NAD-BINDING ROSSMANN FOLD (PF01408), PUTATIVE OXIDOREDUCTASE C TERMINAL DOMAIN (PF16490), STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI- BIOLOGY, OXIDOREDUCTASE
4ooc:A (GLY932) to (GLY1017) DEHYDRATASE DOMAIN OF THE POLYKETIDE PPSC FROM MYCOBACTERIUM TUBERCULOSIS | DEHYDRATASE, TRANSFERASE
5cu2:A (SER51) to (GLU114) CRYSTAL STRUCTURE OF CK2ALPHA WITH 2-HYDROXY-5-METHYLBENZOIC ACID AND (METHYL 4-((3-(3-CHLORO-4-(PHENYL)BENZYLAMINO)PROPYL)AMINO)-4- OXOBUTANOAT BOUND | CK2ALPHA, CK2A, FRAGMENT BASED DRUG DISCOVERY, HIGH CONCENTRATION SCREENING, SELECTIVE ATP COMPETITIVE INHIBITORS, SURFACE ENTROPHY REDUCTION, TRANSFERASE
4a9r:A (GLU233) to (VAL300) CRYSTAL STRUCTURE OF HUMAN CHK2 IN COMPLEX WITH BENZIMIDAZOLE CARBOXAMIDE INHIBITOR | TRANSFERASE, KINASE
4a9s:A (GLU233) to (LEU301) CRYSTAL STRUCTURE OF HUMAN CHK2 IN COMPLEX WITH BENZIMIDAZOLE CARBOXAMIDE INHIBITOR | TRANSFERASE
4a9t:A (GLY232) to (VAL300) CRYSTAL STRUCTURE OF HUMAN CHK2 IN COMPLEX WITH BENZIMIDAZOLE CARBOXAMIDE INHIBITOR | TRANSFERASE
4a9u:A (GLU233) to (VAL300) CRYSTAL STRUCTURE OF HUMAN CHK2 IN COMPLEX WITH BENZIMIDAZOLE CARBOXAMIDE INHIBITOR | TRANSFERASE
4aa4:A (GLY36) to (THR106) P38ALPHA MAP KINASE BOUND TO CMPD 22 | SERINE/THREONINE KINASE, TRANSFERASE
3kf7:A (GLY36) to (HIS107) CRYSTAL STRUCTURE OF HUMAN P38ALPHA COMPLEXED WITH A TRIAZOLOPYRIMIDINE COMPOUND | TWO LOBES, ATP POCKET, PEPTIDE FLIP, ATP-BINDING, KINASE, NUCLEOTIDE- BINDING, NUCLEUS, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
1xxa:A (ASP88) to (THR134) C-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR/ L- ARGININE COMPLEX; PB DERIVATIVE | COMPLEX (DNA BINDING PROTEIN/PEPTIDE)
1xxa:C (ILE89) to (THR134) C-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR/ L- ARGININE COMPLEX; PB DERIVATIVE | COMPLEX (DNA BINDING PROTEIN/PEPTIDE)
1xxa:D (ILE89) to (THR134) C-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR/ L- ARGININE COMPLEX; PB DERIVATIVE | COMPLEX (DNA BINDING PROTEIN/PEPTIDE)
1xxa:E (ASP88) to (THR134) C-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR/ L- ARGININE COMPLEX; PB DERIVATIVE | COMPLEX (DNA BINDING PROTEIN/PEPTIDE)
1xxa:F (ILE89) to (THR134) C-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR/ L- ARGININE COMPLEX; PB DERIVATIVE | COMPLEX (DNA BINDING PROTEIN/PEPTIDE)
1xxb:A (ILE89) to (THR134) C-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR/ L-ARGININE COMPLEX | COMPLEX (DNA BINDING PROTEIN-PEPTIDE), COMPLEX (DNA BINDING PROTEIN- PEPTIDE) COMPLEX
2zr2:A (ALA353) to (THR406) CRYSTAL STRUCTURE OF SERYL-TRNA SYNTHETASE FROM PYROCOCCUS HORIKOSHII COMPLEXED WITH ATP | COILED-COIL, HOMODIMER, AMINOACYL-TRNA SYNTHETASE, ATP- BINDING, CYTOPLASM, LIGASE, NUCLEOTIDE-BINDING, PROTEIN BIOSYNTHESIS, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
3khz:B (ASP203) to (HIS269) CRYSTAL STRUCTURE OF R350A MUTANT OF STAPHYLOCOCCUS AUREUS METALLOPEPTIDASE (SAPEP/DAPE) IN THE APO-FORM | R350A MUTANT-DIPEPTIDASE, DAPE, METALLOPEPTIDASE, DIPEPTIDASE, HYDROLASE, METAL-BINDING, METALLOPROTEASE, PROTEASE
4acc:A (GLY68) to (ASP133) GSK3B IN COMPLEX WITH INHIBITOR | TRANSFERASE
4acg:B (GLY68) to (LEU130) GSK3B IN COMPLEX WITH INHIBITOR | TRANSFERASE
4ach:B (GLY68) to (LEU130) GSK3B IN COMPLEX WITH INHIBITOR | TRANSFERASE
2zug:A (ALA2) to (CYS46) CRYSTAL STRUCTURE OF WSSV ICP11 | DNA MIMIC PROTEIN, DIMER, WHITE SPOT SYNDROME VIRUS, VIRAL PROTEIN
2zug:B (ALA2) to (CYS46) CRYSTAL STRUCTURE OF WSSV ICP11 | DNA MIMIC PROTEIN, DIMER, WHITE SPOT SYNDROME VIRUS, VIRAL PROTEIN
2zvf:A (CYS837) to (GLN885) CRYSTAL STRUCTURE OF ARCHAEOGLOBUS FULGIDUS ALANYL-TRNA SYNTHETASE C-TERMINAL DIMERIZATION DOMAIN | ALANYL-TRNA SYNTHETASE, C-TERMINAL, OLIGOMERIZATION DOMAIN, AMINOACYL-TRNA SYNTHETASE, ATP-BINDING, CYTOPLASM, LIGASE, NUCLEOTIDE-BINDING, PROTEIN BIOSYNTHESIS, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
2zvf:F (GLY836) to (GLN885) CRYSTAL STRUCTURE OF ARCHAEOGLOBUS FULGIDUS ALANYL-TRNA SYNTHETASE C-TERMINAL DIMERIZATION DOMAIN | ALANYL-TRNA SYNTHETASE, C-TERMINAL, OLIGOMERIZATION DOMAIN, AMINOACYL-TRNA SYNTHETASE, ATP-BINDING, CYTOPLASM, LIGASE, NUCLEOTIDE-BINDING, PROTEIN BIOSYNTHESIS, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
2zvf:G (GLY833) to (GLN885) CRYSTAL STRUCTURE OF ARCHAEOGLOBUS FULGIDUS ALANYL-TRNA SYNTHETASE C-TERMINAL DIMERIZATION DOMAIN | ALANYL-TRNA SYNTHETASE, C-TERMINAL, OLIGOMERIZATION DOMAIN, AMINOACYL-TRNA SYNTHETASE, ATP-BINDING, CYTOPLASM, LIGASE, NUCLEOTIDE-BINDING, PROTEIN BIOSYNTHESIS, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
2zvf:H (CYS837) to (GLN885) CRYSTAL STRUCTURE OF ARCHAEOGLOBUS FULGIDUS ALANYL-TRNA SYNTHETASE C-TERMINAL DIMERIZATION DOMAIN | ALANYL-TRNA SYNTHETASE, C-TERMINAL, OLIGOMERIZATION DOMAIN, AMINOACYL-TRNA SYNTHETASE, ATP-BINDING, CYTOPLASM, LIGASE, NUCLEOTIDE-BINDING, PROTEIN BIOSYNTHESIS, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI
4ag8:A (ALA851) to (GLU917) CRYSTAL STRUCTURE OF THE VEGFR2 KINASE DOMAIN IN COMPLEX WITH AXITINIB (AG-013736) (N-METHYL-2-(3-((E)-2-PYRIDIN-2- YL-VINYL)-1H-INDAZOL-6-YLSULFANYL)-BENZAMIDE) | TRANSFERASE, ANGIOGENESIS, NUCLEOTIDE-BINDING, INHIBITOR, PHOSPHORYLATION, TRANSMEMBRANE
4agw:B (GLU280) to (GLU339) DISCOVERY OF A SMALL MOLECULE TYPE II INHIBITOR OF WILD- TYPE AND GATEKEEPER MUTANTS OF BCR-ABL, PDGFRALPHA, KIT, AND SRC KINASES | ATP-BINDING, LIPOPROTEIN, MYRISTATE, PHOSPHOPROTEIN, SH2 DOMAIN, SH3 DOMAIN, TRANSFERASE
3a0w:A (GLY670) to (PRO749) CATALYTIC DOMAIN OF HISTIDINE KINASE THKA (TM1359) FOR MAD PHASING (NUCLEOTIDE FREE FORM 2, ORTHOROMBIC) | ATP-LID, KINASE, PHOSPHOPROTEIN, TRANSFERASE, TWO-COMPONENT REGULATORY SYSTEM
3a0y:A (GLY670) to (PRO749) CATALYTIC DOMAIN OF HISTIDINE KINASE THKA (TM1359) (NUCLEOTIDE FREE FORM 3: 1,2-PROPANEDIOL, ORTHOROMBIC) | ATP-LID, KINASE, PHOSPHOPROTEIN, TRANSFERASE, TWO-COMPONENT REGULATORY SYSTEM
3a0y:B (GLY670) to (PRO749) CATALYTIC DOMAIN OF HISTIDINE KINASE THKA (TM1359) (NUCLEOTIDE FREE FORM 3: 1,2-PROPANEDIOL, ORTHOROMBIC) | ATP-LID, KINASE, PHOSPHOPROTEIN, TRANSFERASE, TWO-COMPONENT REGULATORY SYSTEM
4p7p:A (GLY932) to (GLY1017) STRUCTURE OF THE DEHYDRATASE DOMAIN OF PPSC FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH CROTONYL-COENZYME A | DEHYDRATASE, POLYKETIDE, COMPLEX, TUBERCULOSIS, TRANSFERASE
3a7f:A (GLY36) to (ILE98) HUMAN MST3 KINASE | TWO-LOBE PROTEIN KINASE FOLD, ATP-BINDING, KINASE, NUCLEOTIDE- BINDING, TRANSFERASE
3a7j:A (GLY36) to (GLU100) HUMAN MST3 KINASE IN COMPLEX WITH MNADP | TWO-LOBE PROTEIN KINASE FOLD ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, TRANSFERASE
3a8e:D (THR71) to (VAL151) THE STRUCTURE OF AXCESD OCTAMER COMPLEXED WITH CELLOPENTAOSE | COMPLEX, OCTAMER, TETRAMER OF DIMERS, MOLECULE RING, CELLULOSE BIOSYNTHESIS, BCSD, TC, BIOSYNTHETIC PROTEIN
3a8u:X (ILE375) to (PRO424) CRYSTAL STRUCTURE OF OMEGA-AMINO ACID:PYRUVATE AMINOTRANSFERASE | LARGE PLEATED SHEET, TRANSAMINASE, AMINOTRANSFERASE, PYRIDOXAL PHOSPHATE, TRANSFERASE
4peo:A (MET1) to (ASP73) CRYSTAL STRUCTURE OF A HYPOTHETICAL PROTEIN FROM STAPHYLOCOCCUS AUREUS. | CONSERVED HYPOTHETICAL PROTEIN, UNKNOWN FUNCTION
3kwm:B (LYS117) to (ASN179) CRYSTAL STRUCTURE OF RIBOSE-5-ISOMERASE A | ISOMERASE, STRUCTURAL GENOMICS, IDP02119, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, CSGID
5dew:B (ASP332) to (LEU405) CRYSTAL STRUCTURE OF PAK1 IN COMPLEX WITH AN INHIBITOR COMPOUND 5 | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3adf:A (GLY29) to (GLY111) CRYSTAL STRUCTURE OF A MONOMERIC GREEN FLUORESCENT PROTEIN, AZAMI- GREEN (MAG) | FLUORESCENT PROTEIN, BETA-BARREL, GREEN EMISSION
3l1s:B (GLY68) to (ASP133) 3-ARYL-4-(ARYLHYDRAZONO)-1H-PYRAZOL-5-ONES: HIGHLY LIGAND EFFICIENT AND POTENT INHIBITORS OF GSK3 | KINASE, PYRAZOLE, GSK3, ATP-BINDING, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, WNT SIGNALING PATHWAY, TRANSFERASE
5dh3:B (SER40) to (GLU100) CRYSTAL STRUCTURE OF MST2 IN COMPLEX WITH XMU-MP-1 | MST2, MST1, HIPPO PATHWAY, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1ys3:C (THR361) to (PRO443) CRYSTAL STRUCTURE OF THE ATP BINDING DOMAIN OF PRRB FROM MYCOBACTERIUM TUBERCULOSIS | HISTIDINE KINASE, ATP-BINDING DOMAIN, MYCOBACTERIUM TUBERCULOSIS STRUCTURAL PROTEOMICS PROJECT, XMTB, STRUCTURAL GENOMICS, TRANSFERASE
5dia:A (GLY50) to (ILE119) PIM1 IN COMPLEX WITH CPD36 ((1S,3S)-N1-(6-(5-(PYRIDIN-3-YL)-1H- PYRAZOLO[3,4-C]PYRIDIN-3-YL)PYRIDIN-2-YL)CYCLOHEXANE-1,3-DIAMINE) | PIM-1, KINASE, ATP-COMPETITIVE, STRUCTURE-BASED DRUG DESIGN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3l6j:A (ALA119) to (GLU182) STRUCTURE OF CINACIGUAT (BAY 58-2667) BOUND TO NOSTOC H-NOX DOMAIN | GUANYLYL CYCLASE, BAY58-2667, SIGNALING PROTEIN
3l6j:B (ALA119) to (GLU182) STRUCTURE OF CINACIGUAT (BAY 58-2667) BOUND TO NOSTOC H-NOX DOMAIN | GUANYLYL CYCLASE, BAY58-2667, SIGNALING PROTEIN
1yxu:A (GLY50) to (LEU120) CRYSTAL STRUCTURE OF KINASE PIM1 IN COMPLEX WITH AMP | SER/THR PROTEIN KINASE, TRANSFERASE
1yxu:C (GLY50) to (ILE119) CRYSTAL STRUCTURE OF KINASE PIM1 IN COMPLEX WITH AMP | SER/THR PROTEIN KINASE, TRANSFERASE
1yxu:D (GLY50) to (ILE119) CRYSTAL STRUCTURE OF KINASE PIM1 IN COMPLEX WITH AMP | SER/THR PROTEIN KINASE, TRANSFERASE
5dlt:A (ASP381) to (VAL447) CRYSTAL STRUCTURE OF AUTOTAXIN (ENPP2) WITH 7-ALPHA-HYDROXYCHOLESTEROL | AUTOTAXIN, ENPP2, LPA, STEROIDS, BILE SALTS, HYDROLASE
5dlv:A (ASP381) to (VAL447) CRYSTAL STRUCTURE OF AUTOTAXIN (ENPP2) WITH TAUROURSODEOXYCHOLIC ACID (TUDCA) | AUTOTAXIN, ENPP2, LPA, STEROIDS, BILE SALTS, TUDCA, HYDROLASE
5dlv:B (ASP381) to (VAL447) CRYSTAL STRUCTURE OF AUTOTAXIN (ENPP2) WITH TAUROURSODEOXYCHOLIC ACID (TUDCA) | AUTOTAXIN, ENPP2, LPA, STEROIDS, BILE SALTS, TUDCA, HYDROLASE
5dlw:A (ASP381) to (VAL447) CRYSTAL STRUCTURE OF AUTOTAXIN (ENPP2) WITH TAUROURSODEOXYCHOLIC ACID (TUDCA) AND LYSOPHOSPHATIDIC ACID (LPA) | AUTOTAXIN, ENPP2, LPA, STEROIDS, BILE SALTS, TUDCA, HYDROLASE
3aj1:G (THR71) to (TYR148) THE STRUCTURE OF AXCESD OCTAMER (N-TERMINAL HIS-TAG) FROM ACETOBACTER XYLINUM | ALPHA AND BETA FOLD, OCTAMER, TETRAMER OF DIMERS, MOLECULE RING, CELLULOSE BIOSYNTHESIS, BIOSYNTHETIC PROTEIN, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES
3aj2:C (THR71) to (VAL151) THE STRUCTURE OF AXCESD OCTAMER (C-TERMINAL HIS-TAG) FROM ACETOBACTER XYLINUM | ALPHA AND BETA FOLD, OCTAMER, TETRAMER OF DIMERS, MOLECULE RING, CELLULOSE BIOSYNTHESIS, STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, BIOSYNTHETIC PROTEIN
1z7d:E (ARG340) to (PRO386) ORNITHINE AMINOTRANSFERASE PY00104 FROM PLASMODIUM YOELII | STRUCTURAL GENOMICS CONSORTIUM, SGC, MALARIA, PLASMODIUM YOELII, ORNITHINE AMINOTRANSFERASE
3akk:D (GLY22) to (LYS88) CRYSTAL STRUCTURE OF A HELICOBACTER PYLORI PROINFLAMMATORY KINASE CTKA | PROTEIN KINASE, TRANSFERASE
3akl:A (GLY22) to (LYS88) CRYSTAL STRUCTURE OF A HELICOBACTER PYLORI PROINFLAMMATORY KINASE CTKA | PROTEIN KINASE, TRANSFERASE
3akl:B (GLY22) to (THR91) CRYSTAL STRUCTURE OF A HELICOBACTER PYLORI PROINFLAMMATORY KINASE CTKA | PROTEIN KINASE, TRANSFERASE
3akl:C (GLY22) to (LYS88) CRYSTAL STRUCTURE OF A HELICOBACTER PYLORI PROINFLAMMATORY KINASE CTKA | PROTEIN KINASE, TRANSFERASE
3akl:D (GLY22) to (LYS88) CRYSTAL STRUCTURE OF A HELICOBACTER PYLORI PROINFLAMMATORY KINASE CTKA | PROTEIN KINASE, TRANSFERASE
4ptg:A (GLY68) to (ASP133) STRUCTURE OF A CARBOXAMINE COMPOUND (26) (2-{2-[(CYCLOPROPYLCARBONYL) AMINO]PYRIDIN-4-YL}-4-METHOXYPYRIMIDINE-5-CARBOXAMIDE) TO GSK3B | SERINE/THREONINE KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3lgx:A (ILE382) to (ASP449) STRUCTURE OF PROBABLE D-ALANINE-POLY(PHOSPHORIBITOL) LIGASE SUBUNIT-1 FROM STREPTOCOCCUS PYOGENES WITH ATP | STRUCTURAL GENOMICS, ATP-BINDING, CYTOPLASM, NUCLEOTIDE- BINDING, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, ATP BINDING PROTEIN
3lgx:C (ILE382) to (ASP449) STRUCTURE OF PROBABLE D-ALANINE-POLY(PHOSPHORIBITOL) LIGASE SUBUNIT-1 FROM STREPTOCOCCUS PYOGENES WITH ATP | STRUCTURAL GENOMICS, ATP-BINDING, CYTOPLASM, NUCLEOTIDE- BINDING, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, ATP BINDING PROTEIN
1zc9:A (GLY352) to (ALA408) THE CRYSTAL STRUCTURE OF DIALKYLGLYCINE DECARBOXYLASE COMPLEX WITH PYRIDOXAMINE 5-PHOSPHATE | DGD COMPLEX WITH PYRIDOXAL 5-PHOSPHATE, LYASE
5dud:B (ARG3) to (ILE56) CRYSTAL STRUCTURE OF E. COLI YBGJK | PROTEIN COMPLEX, UNKNOWN FUNCTION
3lla:B (GLY601) to (PRO714) CRYSTAL STRUCTURE OF THE ALPHA-KINASE DOMAIN OF MYOSIN HEAVY CHAIN KINASE A COMPLEX WITH AMPPCP | PROTEIN KINASE LIKE FOLD, ATP-BINDING, KINASE, NUCLEOTIDE- BINDING, SERINE/THREONINE-PROTEIN KINASE, ALPHA-KINASE, COILED COIL, WD REPEAT, TRANSFERASE
1zj9:A (GLY333) to (ILE383) STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS NIRA PROTEIN | NIRA, SULFITE, NITRITE, REDUCTASE, SIROHEME, FE4-S4, CYS-TYR COVALENT BOND, OXIDOREDUCTASE
5dx9:A (THR129) to (PRO183) STRUCTURE OF TREHALOSE-6-PHOSPHATE PHOSPHATASE FROM CRYPTOCOCCUS NEOFORMANS | TREHALOSE-6-PHOSPHATE, PHOSPHATASE, HYDROLASE
1zlt:A (GLY21) to (PHE83) CRYSTAL STRUCTURE OF CHK1 COMPLEXED WITH A HYMENALDISINE ANALOG | KINASE, TRANSFERASE
5dxi:A (ASN129) to (ARG182) STRUCTURE OF C. ALBICANS TREHALOSE-6-PHOSPHATE PHOSPHATASE C-TERMINAL DOMAIN | TREHALOSE-6-PHOSPHATE PHOSPHATASE, HYDROLASE
5dxi:B (ASN129) to (ARG182) STRUCTURE OF C. ALBICANS TREHALOSE-6-PHOSPHATE PHOSPHATASE C-TERMINAL DOMAIN | TREHALOSE-6-PHOSPHATE PHOSPHATASE, HYDROLASE
5dxl:A (PHE129) to (ARG182) STRUCTURE OF ASPERGILLUS FUMIGATUS TREHALOSE-6-PHOSPHATE PHOSPHATASE CRYSTAL FORM 1 | TREHALOSE-6-PHOSPHATE, PHOSPHATASE, HYDROLASE
5dyj:B (GLY601) to (PRO714) MYSOSIN HEAVY CHAIN KINASE A CATALYTIC DOMAIN MUTANT - D663A | KINASE, TRANSFERASE
1zod:A (GLY352) to (ALA408) CRYSTAL STRUCTURE OF DIALKYLGLYCINE DECARBOXYLASE BOUND WITH CESIUM ION | DECARBOXYLASE, PYRIDOXAL, CESIUM, LYASE
5e0o:A (GLY330) to (SER392) BRUGIA MALAYI TREHALOSE-6 PHOSPHATE PHOSPHATASE IN COMPLEX WITH PEG AT THE ACTIVE SITE. | HAD, COMPLEX, PHOSPHATASE, HYDROLASE
4q5e:A (ALA39) to (LEU99) SHIGELLA EFFECTOR KINASE OSPG BOUND TO E2-UB UBCH7-UB CONJUGATE | PROTEIN-PROTEIN COMPLEX, STRUCTURAL GENOMICS, MONTREAL-KINGSTON BACTERIAL STRUCTURAL GENOMICS INITIATIVE, BSGI, KINASE FOLD, INHIBITION OF NF-KB PATHWAY, UNKNOWN FUNCTION, PROTEIN BINDING
4q5h:A (ALA39) to (LEU99) SHIGELLA EFFECTOR KINASE OSPG BOUND TO AMPPNP AND E2-UB UBCH7-UB CONJUGATE | PROTEIN-PROTEIN COMPLEX, STRUCTURAL GENOMICS, MONTREAL-KINGSTON BACTERIAL STRUCTURAL GENOMICS INITIATIVE, BSGI, KINASE FOLD, INHIBITION OF NF-KB PATHWAY, UNKNOWN FUNCTION, PROTEIN BINDING
4q5j:A (ASP896) to (GLU957) CRYSTAL STRUCTURE OF SEMET DERIVATIVE BRI1 IN COMPLEX WITH BKI1 | KINASE DOMAIN, ATP BINDING, PHOSPHORYLATION, SEMET LABELLED, MEMBRANE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4q5j:B (GLY895) to (GLU957) CRYSTAL STRUCTURE OF SEMET DERIVATIVE BRI1 IN COMPLEX WITH BKI1 | KINASE DOMAIN, ATP BINDING, PHOSPHORYLATION, SEMET LABELLED, MEMBRANE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1ztb:A (ARG3) to (GLY78) CRYSTAL STRUCTURE OF CHORISMATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS | BETA-ALPHA-BETA, FLAVOPROTEIN, SHIKIMATE, LIGASE
1zxe:A (LYS615) to (GLU789) CRYSTAL STRUCTURE OF EIF2ALPHA PROTEIN KINASE GCN2: D835N INACTIVATING MUTANT IN APO FORM | TRANSLATION REGULATOR, PROTEIN KINASE, SIGNAL TRANSDUCTION, AMINO- ACID STARVATION, STARVATION STRESS RESPONSE, EIF2ALPHA KINASE, TRANSFERASE
5e4h:A (GLY601) to (PRO714) CRYSTAL STRUCTURE OF APOENZYME ALPHA-KINASE DOMAIN OF MYOSIN-II HEAVY CHAIN KINASE A | ALPHA KINASE, EPK DOMAIN FOLD, TRANSFERASE
5e4h:B (GLY601) to (PRO714) CRYSTAL STRUCTURE OF APOENZYME ALPHA-KINASE DOMAIN OF MYOSIN-II HEAVY CHAIN KINASE A | ALPHA KINASE, EPK DOMAIN FOLD, TRANSFERASE
5e4h:C (GLY601) to (PRO714) CRYSTAL STRUCTURE OF APOENZYME ALPHA-KINASE DOMAIN OF MYOSIN-II HEAVY CHAIN KINASE A | ALPHA KINASE, EPK DOMAIN FOLD, TRANSFERASE
5e4h:D (GLY601) to (PRO714) CRYSTAL STRUCTURE OF APOENZYME ALPHA-KINASE DOMAIN OF MYOSIN-II HEAVY CHAIN KINASE A | ALPHA KINASE, EPK DOMAIN FOLD, TRANSFERASE
5e4h:E (GLY601) to (PRO714) CRYSTAL STRUCTURE OF APOENZYME ALPHA-KINASE DOMAIN OF MYOSIN-II HEAVY CHAIN KINASE A | ALPHA KINASE, EPK DOMAIN FOLD, TRANSFERASE
5e4h:F (GLY601) to (PRO714) CRYSTAL STRUCTURE OF APOENZYME ALPHA-KINASE DOMAIN OF MYOSIN-II HEAVY CHAIN KINASE A | ALPHA KINASE, EPK DOMAIN FOLD, TRANSFERASE
5e4h:G (GLY601) to (PRO714) CRYSTAL STRUCTURE OF APOENZYME ALPHA-KINASE DOMAIN OF MYOSIN-II HEAVY CHAIN KINASE A | ALPHA KINASE, EPK DOMAIN FOLD, TRANSFERASE
5e4h:H (GLY601) to (PRO714) CRYSTAL STRUCTURE OF APOENZYME ALPHA-KINASE DOMAIN OF MYOSIN-II HEAVY CHAIN KINASE A | ALPHA KINASE, EPK DOMAIN FOLD, TRANSFERASE
4q6g:A (LYS321) to (HIS392) CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF ACKRS-1 BOUND WITH N- ACETYL-LYSINE AND ADPNP | TRNA SYNTHETASE, TRNA, AMINO ACIDS, LIGASE
1zyd:A (PHE610) to (GLU789) CRYSTAL STRUCTURE OF EIF2ALPHA PROTEIN KINASE GCN2: WILD- TYPE COMPLEXED WITH ATP. | TRANSLATION REGULATOR, PROTEIN KINASE, SIGNAL TRANSDUCTION, AMINO-ACID STARVATION, STARVATION STRESS RESPONSE, EIF2ALPHA KINASE, TRANSFERASE
5e5o:A (ASP179) to (ASN241) I-SMAMI BOUND TO UNCLEAVED DNA TARGET IN THE PRESENCE OF CALCIUM IONS | LAGLIDADG, I-SMAMI, COMPLEX, UNCLEAVED, HYDROLASE-DNA COMPLEX
5e5p:A (ASP179) to (ASN241) WILD TYPE I-SMAMI IN THE SPACE GROUP OF C121 | LAGLIDADG, I-SMAMI, HYDROLASE
1zyl:A (ARG40) to (PRO107) CRYSTAL STRUCTURE OF HYPOTHETICAL PROTEIN YIHE FROM ESCHERICHIA COLI | HYPOTHETICAL PROTEIN, PUTATIVE PROTEIN KINASE, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, MONTREAL- KINGSTON BACTERIAL STRUCTURAL GENOMICS INITIATIVE, BSGI, UNKNOWN FUNCTION
5e63:A (ASP179) to (ASN241) K262A MUTANT OF I-SMAMI | LAGLIDADG, I-SMAMI, K262A, MUTANT, HYDROLASE-DNA COMPLEX
3m1n:A (LYS121) to (LYS186) CRYSTAL STRUCTURE OF HUMAN SONIC HEDGEHOG N-TERMINAL DOMAIN | HEDGEHOG PROTEINS, SIGNALING, ZINC IONS, SULFATE IONS, AUTOCATALYTIC CLEAVAGE, CELL MEMBRANE, DEVELOPMENTAL PROTEIN, GLYCOPROTEIN, HOLOPROSENCEPHALY, HYDROLASE, LIPOPROTEIN, MEMBRANE, MICROPHTHALMIA, PALMITATE, PROTEASE, SECRETED, SIGNALING PROTEIN
3ay0:A (LEU95) to (HIS151) CRYSTAL STRUCTURE OF METHANOCALDOCOCCUS JANNASCHII TRM5 IN COMPLEX WITH ADENOSINE | ROSSMANN FOLD, METHYLTRANSFERASE, ADOMET BINDING, TRANSFERASE
3m3y:K (LYS18) to (THR77) RNA POLYMERASE II ELONGATION COMPLEX C | TRANSCRIPTION, MRNA, MULTIPROTEIN COMPLEX, MOLECULAR MACHINE, DNA, DNA DAMAGE, CANCER, PLATINUM DRUG, DNA-BINDING, DNA-DIRECTED RNA POLYMERASE, ISOPEPTIDE BOND, MAGNESIUM, METAL-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, TRANSFERASE, UBL CONJUGATION, ZINC, ZINC-FINGER, POLYMORPHISM, CYTOPLASM, DNA REPAIR, TRANSFERASE-DNA-RNA HYBRID COMPLEX
4b56:A (ASN428) to (LEU496) STRUCTURE OF ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE-1 (NPP1) | HYDROLASE
4b56:B (ASN428) to (LEU496) STRUCTURE OF ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE-1 (NPP1) | HYDROLASE
2ab5:A (LYS412) to (SER468) BI3 LAGLIDADG MATURASE | MATURASE, LAGLIDADG ENDONUCLEASE, GROUP I INTRON SPLICING, RNA BINDING, PROTEIN BINDING
2ab5:B (ASP275) to (CYS331) BI3 LAGLIDADG MATURASE | MATURASE, LAGLIDADG ENDONUCLEASE, GROUP I INTRON SPLICING, RNA BINDING, PROTEIN BINDING
2ab5:B (LYS412) to (SER468) BI3 LAGLIDADG MATURASE | MATURASE, LAGLIDADG ENDONUCLEASE, GROUP I INTRON SPLICING, RNA BINDING, PROTEIN BINDING
4bai:A (MSE1) to (GLY78) MYCOBACTERIUM TUBERCULOSIS CHORISMATE SYNTHASE BEFORE EXPOSURE TO 266 NM UV LASER | LYASE
2aeu:A (ILE288) to (LEU347) MJ0158, APO FORM | SELENOCYSTEINE SYNTHASE, PLP, PYRIDOXAL PHOSPHATE, HOMO- OLIGOMERIZATION, UNKNOWN FUNCTION
2aev:A (ILE288) to (LEU347) MJ0158, NABH4-REDUCED FORM | SELENOCYSTEINE SYNTHASE, PLP, PYRIDOXAL PHOSPHATE, HOMO- OLIGOMERIZATION, UNKNOWN FUNCTION
4bbr:K (LYS18) to (THR78) STRUCTURE OF RNA POLYMERASE II-TFIIB COMPLEX | TRANSCRIPTION, RNA POLYMERASE, TFIIB
4qmv:A (GLY36) to (ILE98) MST3 IN COMPLEX WITH PF-03814735, N-{2-[(1S,4R)-6-{[4- (CYCLOBUTYLAMINO)-5-(TRIFLUOROMETHYL)PYRIMIDIN-2-YL]AMINO}-1,2,3,4- TETRAHYDRO-1,4-EPIMINONAPHTHALEN-9-YL]-2-OXOETHYL}ACETAMIDE | PROTEIN KINASE, MST3, STK24, STERILE 20-LIKE KINASE, ATP-BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3mff:C (ASN124) to (TRP185) 1F1E8HU TCR | T-CELL RECEPTOR, PROTEIN METAMORPHISM, ALPHA CONSTANT DOMAIN, IMMUNE SYSTEM
4bda:A (GLU233) to (VAL300) FRAGMENT-BASED SCREENING IDENTIFIES A NEW AREA FOR INHIBITOR BINDING TO CHECKPOINT KINASE 2 (CHK2) | TRANSFERASE
4bdb:A (GLU233) to (VAL300) FRAGMENT-BASED SCREENING IDENTIFIES A NEW AREA FOR INHIBITOR BINDING TO CHECKPOINT KINASE 2 (CHK2) | TRANSFERASE
4bdd:A (GLU233) to (VAL300) FRAGMENT-BASED SCREENING IDENTIFIES A NEW AREA FOR INHIBITOR BINDING TO CHECKPOINT KINASE 2 (CHK2) | TRANSFERASE, INHIBITOR
4bde:A (GLU233) to (VAL300) FRAGMENT-BASED SCREENING IDENTIFIES A NEW AREA FOR INHIBITOR BINDING TO CHECKPOINT KINASE 2 (CHK2) | TRANSFERASE
4bdf:A (GLY232) to (VAL300) FRAGMENT-BASED SCREENING IDENTIFIES A NEW AREA FOR INHIBITOR BINDING TO CHECKPOINT KINASE 2 (CHK2) | TRANSFERASE, INHIBITOR
4bdg:A (GLU233) to (VAL300) FRAGMENT-BASED SCREENING IDENTIFIES A NEW AREA FOR INHIBITOR BINDING TO CHECKPOINT KINASE 2 (CHK2) | TRANSFERASE, INHIBITOR
4bdh:A (GLU233) to (VAL300) FRAGMENT-BASED SCREENING IDENTIFIES A NEW AREA FOR INHIBITOR BINDING TO CHECKPOINT KINASE 2 (CHK2) | TRANSFERASE
4bdk:A (GLY232) to (VAL300) FRAGMENT-BASED SCREENING IDENTIFIES A NEW AREA FOR INHIBITOR BINDING TO CHECKPOINT KINASE 2 (CHK2) | TRANSFERASE
5ekp:A (TYR84) to (ASP162) STRUCTURE OF THE POLYISOPRENYL-PHOSPHATE GLYCOSYLTRANSFERASE GTRB (WT) | GLYCOSYLTRANSFERASE, MEMBRANE PROTEIN, ENZYME, BACTOPRENOL, TRANSFERASE
5eqp:A (SER121) to (GLN207) CRYSTAL STRUCTURE OF CHOLINE KINASE ALPHA-1 BOUND BY 6-[(4-METHYL-1,4- DIAZEPAN-1-YL)METHYL]QUINOLINE (COMPOUND 37) | KINASE, INHIBITOR, COMPLEX, DRUG TARGET, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3mm6:A (GLY76) to (GLY140) DISSIMILATORY SULFITE REDUCTASE CYANIDE COMPLEX | ALPHA-BETA-PROTEIN, OXIDOREDUCTASE
3mm7:A (GLY76) to (GLY140) DISSIMILATORY SULFITE REDUCTASE CARBON MONOXIDE COMPLEX | ALPHA-BETA-PROTEIN, OXIDOREDUCTASE
3mm7:D (GLY79) to (GLY140) DISSIMILATORY SULFITE REDUCTASE CARBON MONOXIDE COMPLEX | ALPHA-BETA-PROTEIN, OXIDOREDUCTASE
3mma:D (GLY76) to (GLY140) DISSIMILATORY SULFITE REDUCTASE PHOSPHATE COMPLEX | ALPHA-BETA-PROTEIN, OXIDOREDUCTASE
3mmb:A (GLY76) to (GLY140) DISSIMILATORY SULFITE REDUCTASE IN COMPLEX WITH THE ENDPRODUCT SULFIDE | ALPHA-BETA-PROTEIN, OXIDOREDUCTASE
3mmb:D (GLY76) to (GLY140) DISSIMILATORY SULFITE REDUCTASE IN COMPLEX WITH THE ENDPRODUCT SULFIDE | ALPHA-BETA-PROTEIN, OXIDOREDUCTASE
3mmc:E (GLY39) to (THR95) STRUCTURE OF THE DISSIMILATORY SULFITE REDUCTASE FROM ARCHAEOGLOBUS FULGIDUS | ALPHA-BETA-PROTEIN, OXIDOREDUCTASE
5exr:C (GLY363) to (SER458) CRYSTAL STRUCTURE OF HUMAN PRIMOSOME | HUMAN PRIMOSOME, COMPLEX, PRIMASE, DNA POLYMERASE ALPHA, PRIMER, DNA REPLICATION, DNA, RNA, REPLICASE, REPLICATION
5exr:G (GLY363) to (SER458) CRYSTAL STRUCTURE OF HUMAN PRIMOSOME | HUMAN PRIMOSOME, COMPLEX, PRIMASE, DNA POLYMERASE ALPHA, PRIMER, DNA REPLICATION, DNA, RNA, REPLICASE, REPLICATION
4qvu:A (ILE153) to (VAL223) CRYSTAL STRUCTURE OF A DUF4931 FAMILY PROTEIN (BCE0241) FROM BACILLUS CEREUS ATCC 10987 AT 2.65 A RESOLUTION | HIT-LIKE FOLD, PF16285 FAMILY, DUF4931, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, UNKNOWN FUNCTION
4qye:A (GLY21) to (PHE83) CHK1 KINASE DOMAIN IN COMPLEX WITH DIARYLPYRAZINE COMPOUND 1 | PROTEIN KINASE, PHOSPHOTRANSFER CATALYST, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4qyf:A (TYR20) to (PHE83) CHK1 KINASE DOMAIN IN COMPLEX WITH AMINOPYRAZINE COMPOUND 13 | PROTEIN KINASE, PHOSPHOTRANSFER CATALYST, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4qyg:A (GLY21) to (PHE83) CHK1 KINASE DOMAIN IN COMPLEX WITH DIAZACARBAZOLE COMPOUND 14 | PROTEIN KINASE, PHOSPHOTRANSFER CATALYST, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4qyg:B (GLY21) to (PHE83) CHK1 KINASE DOMAIN IN COMPLEX WITH DIAZACARBAZOLE COMPOUND 14 | PROTEIN KINASE, PHOSPHOTRANSFER CATALYST, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4qyh:A (GLY21) to (PHE83) CHK1 KINASE DOMAIN IN COMPLEX WITH DIAZACARBAZOLE GNE-783 | PROTEIN KINASE, PHOSPHOTRANSFER CATALYST, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4qyh:B (GLY21) to (PHE83) CHK1 KINASE DOMAIN IN COMPLEX WITH DIAZACARBAZOLE GNE-783 | PROTEIN KINASE, PHOSPHOTRANSFER CATALYST, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3bue:B (SER107) to (VAL152) CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN HEXAMER OF ARGR FROM MYCOBACTERIUM TUBERCULOSIS | L-ARGININE REPRESSOR PROTEIN, DNA BINDING PROTEIN, OLIGOMERIZATION DOMAIN, HEXAMER, L-ARGININE BINDING DOMAIN, STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, AMINO-ACID BIOSYNTHESIS, ARGININE BIOSYNTHESIS, DNA-BINDING, REPRESSOR, TRANSCRIPTION, TRANSCRIPTION REGULATION
3bue:D (SER107) to (VAL152) CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN HEXAMER OF ARGR FROM MYCOBACTERIUM TUBERCULOSIS | L-ARGININE REPRESSOR PROTEIN, DNA BINDING PROTEIN, OLIGOMERIZATION DOMAIN, HEXAMER, L-ARGININE BINDING DOMAIN, STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, AMINO-ACID BIOSYNTHESIS, ARGININE BIOSYNTHESIS, DNA-BINDING, REPRESSOR, TRANSCRIPTION, TRANSCRIPTION REGULATION
3mxw:A (LYS121) to (LYS186) CRYSTAL STRUCTURE SONIC HEDGEHOG BOUND TO THE 5E1 FAB FRAGMENT | ANTIBODY COMPLEX, FAB FRAGMENT, METALLOPROTEASE, CALCIUM BINDING, ZINC HYDROLASE, DEVELOPMENT, MORPHOGEN, SIGNALING PROTEIN
5f94:A (GLY68) to (ASP133) CRYSTAL STRUCTURE OF GSK3B IN COMPLEX WITH COMPOUND 15: 2- [(CYCLOPROPYLCARBONYL)AMINO]-N-(4-METHOXYPYRIDIN-3-YL)PYRIDINE-4- CARBOXAMIDE | GSK3B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5f95:B (GLY68) to (ASP133) CRYSTAL STRUCTURE OF GSK3B IN COMPLEX WITH COMPOUND 18: 2- [(CYCLOPROPYLCARBONYL)AMINO]-N-(4-PHENYLPYRIDIN-3-YL)PYRIDINE-4- CARBOXAMIDE | GSK3B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3bwf:A (GLY50) to (ILE119) CRYSTAL STRUCTURE OF THE HUMAN PIM1 IN COMPLEX WITH AN OSMIUM COMPOUND | TRANSFERASE, PIM1, KINASE, ATP-BINDING, PHOSPHORYLATION, ALTERNATIVE INITIATION, CYTOPLASM, MANGANESE, MEMBRANE, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, PROTO-ONCOGENE, SERINE/THREONINE-PROTEIN KINASE
3n1f:B (LYS126) to (LYS191) CRYSTAL STRUCTURE OF IHHN BOUND TO CDOFN3 | BINDING SITES, CELL ADHESION MOLECULES, CELL CYCLE PROTEINS, CELL LINE, CONSERVED SEQUENCE, FIBRONECTINS, HEDGEHOG PROTEINS, IMMUNOGLOBULIN G, MEMBRANE GLYCOPROTEINS, MEMBRANE PROTEINS, PROTEIN BINDING, TERTIARY, RECEPTORS, CELL SURFACE, SEQUENCE HOMOLOGY, SIGNAL TRANSDUCTION, TUMOR SUPPRESSOR PROTEINS
3n1g:A (ARG122) to (LYS187) CRYSTAL STRUCTURE OF DHHN BOUND TO BOCFN3 | BINDING SITES, CALCIUM, CELL ADHESION MOLECULES, CELL CYCLE PROTEINS, CELL LINE, CONSERVED SEQUENCE, FIBRONECTINS, HEDGEHOG PROTEINS, IMMUNOGLOBULIN G, MEMBRANE GLYCOPROTEINS, MEMBRANE PROTEINS, PROTEIN BINDING, TERTIARY, RECEPTORS, CELL SURFACE, SEQUENCE HOMOLOGY, SIGNAL TRANSDUCTION, TUMOR SUPPRESSOR PROTEINS
3n1o:B (LYS126) to (LYS191) CRYSTAL STRUCTURE OF IHHN | BINDING SITES, CALCIUM, CELL ADHESION MOLECULES, CELL CYCLE PROTEINS, CELL LINE, CONSERVED SEQUENCE, FIBRONECTINS, HEDGEHOG PROTEINS, IMMUNOGLOBULIN G, MEMBRANE GLYCOPROTEINS, MEMBRANE PROTEINS, PROTEIN BINDING, TERTIARY, RECEPTORS, CELL SURFACE, SEQUENCE HOMOLOGY, SIGNAL TRANSDUCTION, TUMOR SUPPRESSOR PROTEINS
3n1o:C (LYS126) to (LYS191) CRYSTAL STRUCTURE OF IHHN | BINDING SITES, CALCIUM, CELL ADHESION MOLECULES, CELL CYCLE PROTEINS, CELL LINE, CONSERVED SEQUENCE, FIBRONECTINS, HEDGEHOG PROTEINS, IMMUNOGLOBULIN G, MEMBRANE GLYCOPROTEINS, MEMBRANE PROTEINS, PROTEIN BINDING, TERTIARY, RECEPTORS, CELL SURFACE, SEQUENCE HOMOLOGY, SIGNAL TRANSDUCTION, TUMOR SUPPRESSOR PROTEINS
3n1p:B (LYS126) to (LYS191) CRYSTAL STRUCTURE OF IHHN BOUND TO BOCFN3 | BINDING SITES, CALCIUM, CELL ADHESION MOLECULES, CELL CYCLE PROTEINS, CELL LINE, CONSERVED SEQUENCE, FIBRONECTINS, HEDGEHOG PROTEINS, IMMUNOGLOBULIN G, MEMBRANE GLYCOPROTEINS, MEMBRANE PROTEINS, PROTEIN BINDING, TERTIARY, RECEPTORS, CELL SURFACE, SEQUENCE HOMOLOGY, SIGNAL TRANSDUCTION, TUMOR SUPPRESSOR PROTEINS
3n1q:A (ARG122) to (LYS187) CRYSTAL STRUCTURE OF DHHN BOUND TO CDOFN3 | BINDING SITES, CALCIUM, CELL ADHESION MOLECULES, CELL CYCLE PROTEINS, CELL LINE, CONSERVED SEQUENCE, FIBRONECTINS, HEDGEHOG PROTEINS, IMMUNOGLOBULIN G, MEMBRANE GLYCOPROTEINS, MEMBRANE PROTEINS, PROTEIN BINDING, TERTIARY, RECEPTORS, CELL SURFACE, SEQUENCE HOMOLOGY, SIGNAL TRANSDUCTION, TUMOR SUPPRESSOR PROTEINS
3n1q:E (GLY120) to (LYS187) CRYSTAL STRUCTURE OF DHHN BOUND TO CDOFN3 | BINDING SITES, CALCIUM, CELL ADHESION MOLECULES, CELL CYCLE PROTEINS, CELL LINE, CONSERVED SEQUENCE, FIBRONECTINS, HEDGEHOG PROTEINS, IMMUNOGLOBULIN G, MEMBRANE GLYCOPROTEINS, MEMBRANE PROTEINS, PROTEIN BINDING, TERTIARY, RECEPTORS, CELL SURFACE, SEQUENCE HOMOLOGY, SIGNAL TRANSDUCTION, TUMOR SUPPRESSOR PROTEINS
3n1r:A (LYS122) to (LYS187) CRYSTAL STRUCTURE OF SHHN | BINDING SITES, CALCIUM, CELL ADHESION MOLECULES, CELL CYCLE PROTEINS, CELL LINE, CONSERVED SEQUENCE, FIBRONECTINS, HEDGEHOG PROTEINS, IMMUNOGLOBULIN G, MEMBRANE GLYCOPROTEINS, MEMBRANE PROTEINS, PROTEIN BINDING, TERTIARY, RECEPTORS, CELL SURFACE, SEQUENCE HOMOLOGY, SIGNAL TRANSDUCTION, TUMOR SUPPRESSOR PROTEINS
3byy:B (GLY124) to (ASP197) MANIPULATING THE COUPLED FOLDING AND BINDING PROCESS DRIVES AFFINITY MATURATION IN A PROTEIN-PROTEIN COMPLEX | SECRETED, SUPERANTIGEN, TOXIN
5f9y:A (LEU321) to (SER403) CRYSTAL STRUCTURE OF PROLYL-TRNA SYNTHETASE FROM CRYPTOSPORIDIUM PARVUM COMPLEXED WITH L-PROLINE AND AMP | SSGCID, PROLYL-TRNA LIGASE, CRYPTOSPORIDIUM PARVUM, ATP BINDING, AMINOACYLATION, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, PRORS, LIGASE
5f9y:B (LEU321) to (ILE408) CRYSTAL STRUCTURE OF PROLYL-TRNA SYNTHETASE FROM CRYPTOSPORIDIUM PARVUM COMPLEXED WITH L-PROLINE AND AMP | SSGCID, PROLYL-TRNA LIGASE, CRYPTOSPORIDIUM PARVUM, ATP BINDING, AMINOACYLATION, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, PRORS, LIGASE
3bzd:B (ASN125) to (ASP197) MANIPULATING THE COUPLED FOLDING AND BINDING PROCESS DRIVES AFFINITY MATURATION IN A PROTEIN-PROTEIN COMPLEX | SUPERANTIGEN, SECRETED, TOXIN
5fai:A (GLN107) to (VAL158) EMG1 N1-SPECIFIC PSEUDOURIDINE METHYLTRANSFERASE | EMG1, METHYLTRANSFERASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE
4bvu:A (ALA39) to (LEU99) STRUCTURE OF SHIGELLA EFFECTOR OSPG IN COMPLEX WITH HOST UBCH5C-UBIQUITIN CONJUGATE | TRANSFERASE-LIGASE-PROTEIN BINDING COMPLEX, KINASE
4bw9:A (LYS321) to (HIS392) PYLRS Y306G, Y384F, I405R MUTANT IN COMPLEX WITH AMP-PNP | LIGASE
4bwa:A (PRO319) to (HIS392) PYLRS Y306G, Y384F, I405R MUTANT IN COMPLEX WITH ADENYLATED NORBORNENE | LIGASE
5fd2:A (GLY469) to (GLN530) B-RAF WILD-TYPE KINASE DOMAIN IN COMPLEX WITH A PURINYLPYRIDINYLAMINO- BASED INHIBITOR | PHOSPHOTRANSFERASE, INHIBITOR, MELANOMA, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4bwx:A (PRO284) to (ASP352) STRUCTURE OF NEUROSPORA CRASSA PAN3 PSEUDOKINASE MUTANT | GENE REGULATION, DEADENYLASE, PAN2, MIRNA, MRNA DECAY
3c4c:B (GLY518) to (GLY593) B-RAF KINASE IN COMPLEX WITH PLX4720 | B-RAF, BRAF, RAF, PROTO-ONCOGENE, SERINE/THREONINE KINASE, ATP-BINDING, CARDIOMYOPATHY, CYTOPLASM, DISEASE MUTATION, METAL-BINDING, NUCLEOTIDE-BINDING, PHORBOL-ESTER BINDING, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, ZINC, ZINC-FINGER
3c4e:C (GLY50) to (ILE119) PIM-1 KINASE DOMAIN IN COMPLEX WITH 3-AMINOPHENYL-7- AZAINDOLE | PIM-1, PROTO-ONCOGENE, SERINE/THREONINE KINASE, ALTERNATIVE INITIATION, ATP-BINDING, CYTOPLASM, MANGANESE, MEMBRANE, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3c4e:D (GLY50) to (LEU120) PIM-1 KINASE DOMAIN IN COMPLEX WITH 3-AMINOPHENYL-7- AZAINDOLE | PIM-1, PROTO-ONCOGENE, SERINE/THREONINE KINASE, ALTERNATIVE INITIATION, ATP-BINDING, CYTOPLASM, MANGANESE, MEMBRANE, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3c5u:A (ASP88) to (ILE166) P38 ALPHA MAP KINASE COMPLEXED WITH A BENZOTHIAZOLE BASED INHIBITOR | SERINE/THREONINE-PROTEIN KINASE, KINASE, TRANSFERASE, P38 MAP KINASE, ALTERNATIVE SPLICING, ATP-BINDING, CYTOPLASM, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN
5fgk:A (GLY33) to (ASP98) CDK8-CYCC IN COMPLEX WITH 8-[3-(3-AMINO-1H-INDAZOL-6-YL)-5-CHLORO- PYRIDINE-4-YL]-2,8-DIAZA-SPIRO[4.5]DECAN-1-ONE | CDK8 KINASE / CYCLIN C, TRANSFERASE
5fj8:A (PHE1171) to (PRO1236) CRYO-EM STRUCTURE OF YEAST RNA POLYMERASE III ELONGATION COMPLEX AT 3.9 A | RNA POLYMERASE III, POL III, TRANSCRIPTION, RNA POLYMERASE
5fj9:A (PHE1171) to (PRO1236) CRYO-EM STRUCTURE OF YEAST APO RNA POLYMERASE III AT 4.6 A | RNA POLYMERASE III, POL III, TRANSCRIPTION, RNA POLYMERASE
5fja:A (PHE1171) to (PRO1236) CRYO-EM STRUCTURE OF YEAST RNA POLYMERASE III AT 4.7 A | TRANSLATION, POL III, TRANSCRIPTION, RNA POLYMERASE,
4c23:A (GLY246) to (LYS290) L-FUCULOSE KINASE | TRANSFERASE, FUCOSE PROCESSING
4c23:B (GLY246) to (THR293) L-FUCULOSE KINASE | TRANSFERASE, FUCOSE PROCESSING
3cgf:A (ASN128) to (ASP207) IRAK-4 INHIBITORS (PART II)- A STRUCTURE BASED ASSESSMENT OF IMIDAZO[1,2 A]PYRIDINE BINDING | KINASE TWO-LOBED STRUCTURE, ALTERNATIVE SPLICING, ATP- BINDING, CHROMOSOMAL REARRANGEMENT, CYTOPLASM, EPILEPSY, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE- PROTEIN KINASE, TRANSFERASE
3cgy:A (GLU397) to (ARG479) CRYSTAL STRUCTURE OF SALMONELLA SENSOR KINASE PHOQ CATALYTIC DOMAIN IN COMPLEX WITH RADICICOL | ALPHA-BETA SANDWICH, BERGERAT FOLD, ATP-BINDING, GROWTH REGULATION, INNER MEMBRANE, KINASE, MAGNESIUM, MEMBRANE, METAL-BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, TRANSFERASE, TRANSMEMBRANE, TWO-COMPONENT REGULATORY SYSTEM, VIRULENCE
3cgy:B (GLU397) to (ARG479) CRYSTAL STRUCTURE OF SALMONELLA SENSOR KINASE PHOQ CATALYTIC DOMAIN IN COMPLEX WITH RADICICOL | ALPHA-BETA SANDWICH, BERGERAT FOLD, ATP-BINDING, GROWTH REGULATION, INNER MEMBRANE, KINASE, MAGNESIUM, MEMBRANE, METAL-BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, TRANSFERASE, TRANSMEMBRANE, TWO-COMPONENT REGULATORY SYSTEM, VIRULENCE
3cgy:C (GLU397) to (ARG479) CRYSTAL STRUCTURE OF SALMONELLA SENSOR KINASE PHOQ CATALYTIC DOMAIN IN COMPLEX WITH RADICICOL | ALPHA-BETA SANDWICH, BERGERAT FOLD, ATP-BINDING, GROWTH REGULATION, INNER MEMBRANE, KINASE, MAGNESIUM, MEMBRANE, METAL-BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, TRANSFERASE, TRANSMEMBRANE, TWO-COMPONENT REGULATORY SYSTEM, VIRULENCE
3cgz:B (GLU397) to (ARG479) CRYSTAL STRUCTURE OF SALMONELLA SENSOR KINASE PHOQ CATALYTIC DOMAIN | ALPHA-BETA SANDWICH, BERGERAT FOLD, ATP-BINDING, GROWTH REGULATION, INNER MEMBRANE, KINASE, MAGNESIUM, MEMBRANE, METAL-BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, TRANSFERASE, TRANSMEMBRANE, TWO-COMPONENT REGULATORY SYSTEM, VIRULENCE
3cgz:C (GLU397) to (ARG479) CRYSTAL STRUCTURE OF SALMONELLA SENSOR KINASE PHOQ CATALYTIC DOMAIN | ALPHA-BETA SANDWICH, BERGERAT FOLD, ATP-BINDING, GROWTH REGULATION, INNER MEMBRANE, KINASE, MAGNESIUM, MEMBRANE, METAL-BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, TRANSFERASE, TRANSMEMBRANE, TWO-COMPONENT REGULATORY SYSTEM, VIRULENCE
4c45:A (GLY25) to (SER80) CRYSTAL STRUCTURE OF HUMAN PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE 2 (PCBD2) | LYASE
4c4m:A (LYS122) to (LYS187) CRYSTAL STRUCTURE OF THE SONIC HEDGEHOG-CHONDROITIN-4-SULPHATE COMPLEX | SIGNALING PROTEIN, HEDGEHOG SIGNALLING, MORPHOGENS, HEPARAN SULPHATE PROTEOGLYCANS, GLYCOSAMINOGLYCANS
4c4n:A (LYS122) to (LYS187) CRYSTAL STRUCTURE OF THE SONIC HEDGEHOG-HEPARIN COMPLEX | SIGNALING PROTEIN, HEDGEHOG SIGNALLING, MORPHOGENS, HEPARAN SULPHATE PROTEOGLYCANS, GLYCOSAMINOGLYCANS
4c4n:B (LYS122) to (LYS187) CRYSTAL STRUCTURE OF THE SONIC HEDGEHOG-HEPARIN COMPLEX | SIGNALING PROTEIN, HEDGEHOG SIGNALLING, MORPHOGENS, HEPARAN SULPHATE PROTEOGLYCANS, GLYCOSAMINOGLYCANS
3nkm:A (ASP381) to (VAL447) CRYSTAL STRUCTURE OF MOUSE AUTOTAXIN | LYSOPHOSPHOLIPASE D, AUTOTAXIN, ENPP2, LYSOPHOSPHATIDIC ACID, HYDROLASE
3nkn:A (ASP381) to (VAL447) CRYSTAL STRUCTURE OF MOUSE AUTOTAXIN IN COMPLEX WITH 14:0-LPA | LYSOPHOSPHOLIPASE D, AUTOTAXIN, ENPP2, LYSOPHOSPHATIDIC ACID, HYDROLASE
3nko:A (ASP381) to (VAL447) CRYSTAL STRUCTURE OF MOUSE AUTOTAXIN IN COMPLEX WITH 16:0-LPA | LYSOPHOSPHOLIPASE D, AUTOTAXIN, ENPP2, LYSOPHOSPHATIDIC ACID, HYDROLASE
3nkp:A (ASP381) to (VAL447) CRYSTAL STRUCTURE OF MOUSE AUTOTAXIN IN COMPLEX WITH 18:1-LPA | LYSOPHOSPHOLIPASE D, AUTOTAXIN, ENPP2, LYSOPHOSPHATIDIC ACID, HYDROLASE
3nkq:A (ASP381) to (VAL447) CRYSTAL STRUCTURE OF MOUSE AUTOTAXIN IN COMPLEX WITH 18:3-LPA | LYSOPHOSPHOLIPASE D, AUTOTAXIN, ENPP2, LYSOPHOSPHATIDIC ACID, HYDROLASE
3nkr:A (ASP381) to (VAL447) CRYSTAL STRUCTURE OF MOUSE AUTOTAXIN IN COMPLEX WITH 22:6-LPA | LYSOPHOSPHOLIPASE D, AUTOTAXIN, ENPP2, LYSOPHOSPHATIDIC ACID, HYDROLASE
4c8b:A (SER29) to (GLU96) STRUCTURE OF THE KINASE DOMAIN OF HUMAN RIPK2 IN COMPLEX WITH PONATINIB | TRANSFERASE, STRUCTURAL GENOMICS
4c8b:B (GLY30) to (GLU96) STRUCTURE OF THE KINASE DOMAIN OF HUMAN RIPK2 IN COMPLEX WITH PONATINIB | TRANSFERASE, STRUCTURAL GENOMICS
3nr9:A (GLY175) to (GLU244) STRUCTURE OF HUMAN CDC2-LIKE KINASE 2 (CLK2) | STRUCTURAL GENOMICS CONSORTIUM, SGC, PROTEIN KINASE, DUAL SPECIFICITY PROTEIN KINASE, TRANSFERASE
3nr9:B (GLY175) to (GLU244) STRUCTURE OF HUMAN CDC2-LIKE KINASE 2 (CLK2) | STRUCTURAL GENOMICS CONSORTIUM, SGC, PROTEIN KINASE, DUAL SPECIFICITY PROTEIN KINASE, TRANSFERASE
5ftg:A (LEU124) to (GLN207) DESIGN, SYNTHESIS, CRYSTALLIZATION AND BIOLOGICAL EVALUATION OF NEW SYMMETRICAL BISCATIONIC COMPOUNDS AS SELECTIVE INHIBITORS OF HUMAN CHOLINE KINASE ALPHA1 (CHOKALPHA1) | TRANSFERASE, BISCATIONIC INHIBITOR, DOCKING STUDIES
3com:B (GLY42) to (GLU103) CRYSTAL STRUCTURE OF MST1 KINASE | KINASE, MST1, SERINE/THREONINE-PROTEIN KINASE 4, STE20-LIKE KINASE, PSI, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, ALTERNATIVE SPLICING, APOPTOSIS, ATP- BINDING, COILED COIL, CYTOPLASM, MAGNESIUM, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, TRANSFERASE
3cpc:B (GLN847) to (GLU917) CRYSTAL STRUCTURE OF THE VEGFR2 KINASE DOMAIN IN COMPLEX WITH A PYRIDONE INHIBITOR | RECEPTOR TYROSINE KINASE, ANGIOGENESIS, ATP-BINDING, DEVELOPMENTAL PROTEIN, DIFFERENTIATION, GLYCOPROTEIN, HOST-VIRUS INTERACTION, IMMUNOGLOBULIN DOMAIN, MEMBRANE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, TRANSFERASE, TRANSMEMBRANE, TYROSINE-PROTEIN KINASE
5fut:A (LEU124) to (GLN207) PLASMODIUM FALCIPARUM CHOLINE KINASE INHIBITION LEADS TO A MAJOR DECREASE OF PHOSPHATIDYLETHANOLAMINE | TRANSFERASE, CHOLINE KINASE, PHOSPHATIDYLETANOLAMINE, INHIBITORS
3nvr:A (GLY111) to (LYS179) MODULATING HEME REDOX POTENTIAL THROUGH PROTEIN-INDUCED PORPHYRIN DISTORTION | H-NOX, HEMOPROTEIN, HEME COFACTOR, SIGNALING PROTEIN
4rqe:C (PRO291) to (TRP382) HUMAN SERYL-TRNA SYNTHETASE DIMER COMPLEXED WITH TWO MOLECULES OF TRNASEC | AMINOACYL-TRNA SYNTHETASE, CLASSII AARS, AMINOACYLATION, SERINE, CYTOSOL, LIGASE-RNA COMPLEX
4cg8:A (LEU124) to (GLN207) HUMAN CHOLINE KINASE A1 IN COMPLEX WITH COMPOUND 14 | TRANSFERASE, DRUG TARGET, CANCER
4ch5:A (LYS321) to (HIS392) STRUCTURE OF PYRROLYSYL-TRNA SYNTHETASE IN COMPLEX WITH ADENYLATED PROPIONYL LYSINE | LIGASE, NON-NATURAL AMINO ACID, PYRROLYSINE
4ch6:A (LYS321) to (HIS392) STRUCTURE OF PYRROLYSYL-TRNA SYNTHETASE IN COMPLEX WITH ADENYLATED PROPARGYLOXYCARBONYL LYSINE | LIGASE, NON-NATURAL AMINO ACID, PYRROLYSINE
4rvm:A (GLU22) to (PHE83) CHK1 KINASE DOMAIN WITH DIAZACARBAZOLE COMPOUND 19 | PROTEIN KINASE, PHOSPHOTRANSFER CATALYST, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3cw4:A (GLY151) to (ARG203) LARGE C-TERMINAL DOMAIN OF INFLUENZA A VIRUS RNA-DEPENDENT POLYMERASE PB2 | RNA POLYMERASE, MITOCHONDRION, MRNA CAPPING, MRNA PROCESSING, NUCLEUS, VIRION, TRANSFERASE
3cwv:B (ARG188) to (TRP244) CRYSTAL STRUCTURE OF B-SUBUNIT OF THE DNA GYRASE FROM MYXOCOCCUS XANTHUS | STRUCTURAL GENOMICS, UNKNOWN FUNCTION, DNA GYRASE, B-SUBUNIT, ATP- BINDING, ISOMERASE, NUCLEOTIDE-BINDING, TOPOISOMERASE, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
3cx5:L (VAL37) to (LEU109) STRUCTURE OF COMPLEX III WITH BOUND CYTOCHROME C IN REDUCED STATE AND DEFINITION OF A MINIMAL CORE INTERFACE FOR ELECTRON TRANSFER. | COMPLEX III, CYTOCHROME C, ELECTRON TRANSFER COMPLEX, CYTOCHROME BC1 COMPLEX, MITOCHONDRIALTRANSMEMBRANE COMPLEX, RESPIRATORY CHAIN, TRANSIENT PROTEIN-PROTEIN INTERACTION, ELECTRON TRANSPORT, INNER MEMBRANE, MITOCHONDRION, TRANSIT PEPTIDE, TRANSPORT, PHOSPHOPROTEIN, HEME, IRON, METAL-BINDING, IRON-SULFUR, OXIDOREDUCTASE, METHYLATION
4rzv:A (GLY469) to (GLN530) CRYSTAL STRUCTURE OF THE BRAF (R509H) KINASE DOMAIN MONOMER BOUND TO VEMURAFENIB | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4rzv:B (TYR472) to (GLN530) CRYSTAL STRUCTURE OF THE BRAF (R509H) KINASE DOMAIN MONOMER BOUND TO VEMURAFENIB | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4rzw:A (THR470) to (GLN530) CRYSTAL STRUCTURE OF BRAF (R509H) KINASE DOMAIN BOUND TO AZ628 | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4rzw:B (LYS473) to (GLN530) CRYSTAL STRUCTURE OF BRAF (R509H) KINASE DOMAIN BOUND TO AZ628 | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3d1m:B (LYS122) to (LYS187) CRYSTAL STRUCTURE OF SONIC HEDGEHOG BOUND TO THE THIRD FNIII DOMAIN OF CDO | FIBRONECTIN PROTEIN-PROTEIN COMPLEX, AUTOCATALYTIC CLEAVAGE, DEVELOPMENTAL PROTEIN, GLYCOPROTEIN, HYDROLASE, LIPOPROTEIN, MEMBRANE, PALMITATE, PROTEASE, SECRETED, IMMUNOGLOBULIN DOMAIN, TRANSMEMBRANE, SIGNALING PROTEIN - CELL ADHESION COMPLEX
4cqe:A (GLY469) to (GLN530) B-RAF KINASE V600E MUTANT IN COMPLEX WITH A DIARYLTHIAZOLE B-RAF INHIBITOR | TRANSFERASE, INHIBITOR COMPLEX
4cqe:B (THR470) to (GLN530) B-RAF KINASE V600E MUTANT IN COMPLEX WITH A DIARYLTHIAZOLE B-RAF INHIBITOR | TRANSFERASE, INHIBITOR COMPLEX
4cs4:A (LYS321) to (HIS392) CATALYTIC DOMAIN OF PYRROLYSYL-TRNA SYNTHETASE MUTANT Y306A, Y384F IN COMPLEX WITH AMPPNP | LIGASE, AMINOACYL-TRNA SYNTHETASE, NONCANONICAL AMINO ACIDS
4cti:A (GLY453) to (LEU535) ESCHERICHIA COLI ENVZ HISTIDINE KINASE CATALYTIC PART FUSED TO ARCHAEOGLOBUS FULGIDUS AF1503 HAMP DOMAIN | SIGNALING PROTEIN, TWO-COMPONENT SIGNAL TRANSDUCTION, TCST, DHP DOMAIN, CA DOMAIN, PHOSPHORYL TRANSFER, STUTTER
4cti:C (GLY453) to (LEU535) ESCHERICHIA COLI ENVZ HISTIDINE KINASE CATALYTIC PART FUSED TO ARCHAEOGLOBUS FULGIDUS AF1503 HAMP DOMAIN | SIGNALING PROTEIN, TWO-COMPONENT SIGNAL TRANSDUCTION, TCST, DHP DOMAIN, CA DOMAIN, PHOSPHORYL TRANSFER, STUTTER
3db9:A (VAL149) to (ALA232) CRYSTAL STRUCTURE OF UPF0317 PROTEIN ATU3911 FROM AGROBACTERIUM TUMEFACIENS. NORTHEAST STRCUTURAL GENOMICS TARGET ATR186 | BELONGS TO THE UPF0317 FAMILY, AGROBACTERIUM TUMEFACIENS, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM, NESG, UNKNOWN FUNCTION
4tqf:A (PRO319) to (HIS392) CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF IFRS BOUND WITH 2-(5- BROMOTHIENYL)-L-ALA AND ATP | AMINO ACYL-TRNA SYNTHETASES, ARCHAEAL PROTEINS, EVOLUTION, MOLECULAR, GENETIC CODE, SUBSTRATE SPECIFICITY, LIGASE
3og7:A (GLY469) to (GLN530) B-RAF KINASE V600E ONCOGENIC MUTANT IN COMPLEX WITH PLX4032 | B-RAF, BRAF, PROTO-ONCOGENE, V600E, KINASE, TRANSFERASE
3og7:B (GLY518) to (GLY593) B-RAF KINASE V600E ONCOGENIC MUTANT IN COMPLEX WITH PLX4032 | B-RAF, BRAF, PROTO-ONCOGENE, V600E, KINASE, TRANSFERASE
5gjd:A (ALA53) to (GLU105) CRYSTAL STRUCTURE OF HUMAN TAK1/TAB1 FUSION PROTEIN IN COMPLEX WITH LIGAND 2 | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX, TAK1-TAB1 KINASE
3ohe:A (VAL23) to (GLN98) CRYSTAL STRUCTURE OF A HISTIDINE TRIAD PROTEIN (MAQU_1709) FROM MARINOBACTER AQUAEOLEI VT8 AT 1.20 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, HYDROLASE
3ohe:B (VAL23) to (GLN98) CRYSTAL STRUCTURE OF A HISTIDINE TRIAD PROTEIN (MAQU_1709) FROM MARINOBACTER AQUAEOLEI VT8 AT 1.20 A RESOLUTION | STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-BIOLOGY, HYDROLASE
3oii:A (GLN111) to (VAL162) CRYSTAL STRUCTURE OF SACCHAROMYCES CEREVISIAE NEP1/EMG1 BOUND TO S- ADENOSYLHOMOCYSTEINE | EMG1, SCNEP1, SPOUT, RIBOSOME BIOGENESIS, METHYLTRANSFERASE, RRNA PROCESSING, RIBOSOMAL PROTEIN
3oii:B (GLN111) to (VAL162) CRYSTAL STRUCTURE OF SACCHAROMYCES CEREVISIAE NEP1/EMG1 BOUND TO S- ADENOSYLHOMOCYSTEINE | EMG1, SCNEP1, SPOUT, RIBOSOME BIOGENESIS, METHYLTRANSFERASE, RRNA PROCESSING, RIBOSOMAL PROTEIN
3oij:B (GLN111) to (VAL162) CRYSTAL STRUCTURE OF SACCHAROMYCES CEREVISIAE NEP1/EMG1 BOUND TO S- ADENOSYLHOMOCYSTEINE AND 2 MOLECULES OF COGNATE RNA | EMG1, SCNEP1, SPOUT, RIBOSOME BIOGENESIS, METHYLTRANSFERASE, RRNA PROCESSING, RIBOSOMAL PROTEIN
3oin:A (GLN111) to (VAL162) CRYSTAL STRUCTURE OF SACCHAROMYCES CEREVISIAE NEP1/EMG1 BOUND TO S- ADENOSYLHOMOCYSTEINE AND 1 MOLECULE OF COGNATE RNA | EMG1, SCNEP1, SPOUT, RIBOSOME BIOGENESIS, METHYLTRANSFERASE, RRNA PROCESSING, RIBOSOMAL PROTEIN
3oin:B (GLN111) to (VAL162) CRYSTAL STRUCTURE OF SACCHAROMYCES CEREVISIAE NEP1/EMG1 BOUND TO S- ADENOSYLHOMOCYSTEINE AND 1 MOLECULE OF COGNATE RNA | EMG1, SCNEP1, SPOUT, RIBOSOME BIOGENESIS, METHYLTRANSFERASE, RRNA PROCESSING, RIBOSOMAL PROTEIN
3omv:B (THR362) to (GLN422) CRYSTAL STRUCTURE OF C-RAF (RAF-1) | SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3oor:A (ASP44) to (THR103) I-SCEI MUTANT (K86R/G100T)COMPLEXED WITH C/G+4 DNA SUBSTRATE | HOMING ENDONUCLEASE, INTRON HOMING, LAGLIDADG, HYDROLASE-DNA COMPLEX, I-SCEI MUTANT (K86R/G100T)
5h3w:A (GLU164) to (ILE211) THE STRUCTURE OF THE C-TERMINAL OF THE FIBRONECTIN/FIBRINOGEN-BINDING PROTEIN FROM STREPTOCOCCUS SUIS (FBPS) | NOVEL FOLD, FIBRONECTIN-BINDING PROPERTY, CELL ADHESION
5h3w:B (GLU164) to (ILE211) THE STRUCTURE OF THE C-TERMINAL OF THE FIBRONECTIN/FIBRINOGEN-BINDING PROTEIN FROM STREPTOCOCCUS SUIS (FBPS) | NOVEL FOLD, FIBRONECTIN-BINDING PROPERTY, CELL ADHESION
3dqw:A (GLY279) to (GLU339) C-SRC KINASE DOMAIN THR338ILE MUTANT IN COMPLEX WITH ATPGS | SRC, KINASE, ACTIVE, GATEKEEPER, ATP-BINDING, LIPOPROTEIN, MYRISTATE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, PROTO-ONCOGENE, SH2 DOMAIN, SH3 DOMAIN, TRANSFERASE, TYROSINE-PROTEIN KINASE
3ds6:D (GLY36) to (HIS107) P38 COMPLEX WITH A PHTHALAZINE INHIBITOR | KINASE INHIBITOR COMPLEX, ALTERNATIVE SPLICING, ATP-BINDING, CYTOPLASM, KINASE, NUCLEOTIDE-BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
4u1t:A (GLY272) to (ILE363) THE CRYSTAL STRUCTURE OF HOLO CALE6, A METHIONINE GAMMA LYASE FROM MICROMONOSPORA ECHINOSPORA | LYASE
4u1t:C (GLY272) to (ILE363) THE CRYSTAL STRUCTURE OF HOLO CALE6, A METHIONINE GAMMA LYASE FROM MICROMONOSPORA ECHINOSPORA | LYASE
4u1t:H (GLY272) to (ILE363) THE CRYSTAL STRUCTURE OF HOLO CALE6, A METHIONINE GAMMA LYASE FROM MICROMONOSPORA ECHINOSPORA | LYASE
4u3z:B (GLY37) to (GLU106) APO MAP4K4 T181E PHOSPHOMIMETIC MUTANT | KINASE, TRANSFERASE
4u40:B (GLY37) to (GLU106) MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 4 (MAP4K4) BOUND TO AMPPNP | KINASE, TRANSFERASE
3ouy:B (GLU41) to (VAL103) HOW THE CCA-ADDING ENZYME SELECTS ADENINE OVER CYTOSINE AT POSITION 76 OF TRNA | PROTEIN-RNA COMPLEX, ROSSMANN FOLD, CCA-ADDING, TRNA, PHOSPHOLATION, TRANSFERASE-RNA COMPLEX
3ov7:B (GLU41) to (LYS105) HOW THE CCA-ADDING ENZYME SELECTS ADENINE OVER CYTOSINE IN POSITION 76 OF TRNA | PROTEIN-RNA, ROSSMANN FOLD, CCA-ADDING, TRNA, NUCLEOTIDYLTRANSFER, TRANSFERASE-RNA COMPLEX
3dxm:D (ASP149) to (PRO229) STRUCTURE OF BOS TAURUS ARP2/3 COMPLEX WITH BOUND INHIBITOR CK0993548 | BETA-PROPELLER, STRUCTURAL PROTEIN
3p23:D (CYS630) to (ILE709) CRYSTAL STRUCTURE OF THE HUMAN KINASE AND RNASE DOMAINS IN COMPLEX WITH ADP | KINASE DOMAIN, KINASE AND RNASE FUNCTION, ATP BINDING SSRNA BINDING, DEPHOSPHORYLATED, HYDROLASE, TRANSFERASE
3dz8:A (GLU11) to (ARG66) CRYSTAL STRUCTURE OF HUMAN RAB3B GTPASE BOUND WITH GDP | RAS, GDP, GTPASE, STRUCTURAL GENOMICS CONSORTIUM, SGC, CELL MEMBRANE, GTP-BINDING, LIPOPROTEIN, MEMBRANE, METHYLATION, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, PRENYLATION, PROTEIN TRANSPORT, TRANSPORT
4u7o:A (VAL525) to (PRO608) ACTIVE HISTIDINE KINASE BOUND WITH ATP | HISTIDINE KINASE, PHOSPHORYLTRANSFERASE, ATP, ACTIVE STATE, ASYMMETRIC BENDING, TRANSFERASE
5hpn:B (VAL4) to (GLY70) A CIRCULARLY PERMUTED PDUA FORMING AN ICOSAHEDRAL CAGE | PDUA, PROTEIN DESIGN, ICOSAHEDRON, CAGE, BMC, MCP, MICROCOMPARTMENT, DESIGN, DE NOVO PROTEIN
4u99:A (HIS117) to (ASN180) CRYSTAL STRUCTURE OF AN H-NOX PROTEIN FROM S. ONEIDENSIS IN THE FE(II) LIGATION STATE, Q154A/Q155A/K156A MUTANT | H-NOX, HEMOPROTEIN, GAS SENSOR, SIGNALING PROTEIN
4u99:B (PRO113) to (ASN180) CRYSTAL STRUCTURE OF AN H-NOX PROTEIN FROM S. ONEIDENSIS IN THE FE(II) LIGATION STATE, Q154A/Q155A/K156A MUTANT | H-NOX, HEMOPROTEIN, GAS SENSOR, SIGNALING PROTEIN
4u9b:A (HIS117) to (ASN180) CRYSTAL STRUCTURE OF AN H-NOX PROTEIN FROM S. ONEIDENSIS IN THE FE(II)NO LIGATION STATE | H-NOX, HEMOPROTEIN, GAS SENSOR
4u9g:A (HIS117) to (ASN180) CRYSTAL STRUCTURE OF AN H-NOX PROTEIN FROM S. ONEIDENSIS IN THE FE(II)CO LIGATION STATE, Q154A/Q155A/K156A MUTANT | H-NOX, HEMOPROTEIN, GAS SENSOR, SIGNALING PROTEIN
4u9g:B (PRO113) to (ASN180) CRYSTAL STRUCTURE OF AN H-NOX PROTEIN FROM S. ONEIDENSIS IN THE FE(II)CO LIGATION STATE, Q154A/Q155A/K156A MUTANT | H-NOX, HEMOPROTEIN, GAS SENSOR, SIGNALING PROTEIN
4u9k:A (HIS117) to (ASN180) CRYSTAL STRUCTURE OF AN H-NOX PROTEIN FROM S. ONEIDENSIS IN THE MN(II)NO LIGATION STATE, Q154A/Q155A/K156A MUTANT | H-NOX, HEMOPROTEIN, GAS SENSOR, SIGNALING PROTEIN
4u9k:B (PRO113) to (ASN180) CRYSTAL STRUCTURE OF AN H-NOX PROTEIN FROM S. ONEIDENSIS IN THE MN(II)NO LIGATION STATE, Q154A/Q155A/K156A MUTANT | H-NOX, HEMOPROTEIN, GAS SENSOR, SIGNALING PROTEIN
3pa4:A (GLY21) to (PHE83) X-RAY CRYSTAL STRUCTURE OF COMPOUND 2A BOUND TO HUMAN CHK1 KINASE DOMAIN | KINASE, PHOSPHATASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4un0:C (GLY739) to (GLU814) CRYSTAL STRUCTURE OF THE HUMAN CDK12-CYCLINK COMPLEX | TRANSFERASE
4un0:D (GLN740) to (GLU814) CRYSTAL STRUCTURE OF THE HUMAN CDK12-CYCLINK COMPLEX | TRANSFERASE
3pj2:A (GLY414) to (GLU475) CRYSTAL STRUCTURE OF BTK KINASE DOMAIN COMPLEXED WITH 2-[4-(2- DIETHYLAMINO-ETHOXY)-PHENYLAMINO]-6-(4-FLUORO-PHENOXY)-8-METHYL-8H- PYRIDO[2,3-D]PYRIMIDIN-7-ONE | HELIX C-OUT, DFG-IN, TRANSFERASE, TRANSFERASE-INHIBITOR COMPLEX
3pj3:A (GLY414) to (GLU475) CRYSTAL STRUCTURE OF BTK KINASE DOMAIN COMPLEXED WITH 2-METHYL-5-[(E)- (3-PHENYL-ACRYLOYL)AMINO]-N-(2-PHENYL-3H-IMIDAZO[4,5-B]PYRIDIN-6-YL)- BENZAMIDE | HELIX C-IN, DFG-OUT, TRANSFERASE, TRANSFERASE-INHIBITOR COMPLEX
5iex:A (GLY16) to (PHE80) CRYSTAL STRUCTURE OF (R,S)-S-{4-[(5-BROMO-4-{[(2R,3R)-2-HYDROXY-1- METHYLPROPYL]OXY}- PYRIMIDIN-2-YL)AMINO]PHENYL}-S- CYCLOPROPYLSULFOXIMIDE BOUND TO CDK2 | ANTINEOPLASTIC AGENTS, CYCLIN-DEPENDENT KINASES, DOSE-RESPONSE RELATIONSHIP, DRUG, DRUG DISCOVERY, HELA CELLS, MOLECULAR STRUCTURE, NEOPLASMS, PROTEIN KINASE INHIBITORS, PYRIMIDINES, STRUCTURE- ACTIVITY RELATIONSHIP, STRUCTURE-KINETICS RELATIONSHIP, SULFOXIDES, BIOPHYSICAL ASSAYS, TUMOR, HUMANS, TRANSFERASE
4ec9:A (GLY31) to (ASP104) CRYSTAL STRUCTURE OF FULL-LENGTH CDK9 IN COMPLEX WITH CYCLIN T | CYCLIN DEPENDENT KINASE, CYCLIN, KINASE, PHOSPHORYLATION, NUCLEAR, TRANSFERASE-PROTEIN BINDING COMPLEX
3pup:A (GLY68) to (LEU130) STRUCTURE OF GLYCOGEN SYNTHASE KINASE 3 BETA (GSK3B) IN COMPLEX WITH A RUTHENIUM OCTASPORINE LIGAND (OS1) | WNT SIGNALING PATHWAY, SERINE/THREONINE-PROTEIN KINASE, RUTHENIUM GLYCOGEN SYNTHASE KINASE PICOMOLAR, NUCLEOTIDE-BINDING, KINASE, TRANSFERASE, ATP-BINDING, PHOSPHOPROTEIN
3pup:B (GLY68) to (LEU130) STRUCTURE OF GLYCOGEN SYNTHASE KINASE 3 BETA (GSK3B) IN COMPLEX WITH A RUTHENIUM OCTASPORINE LIGAND (OS1) | WNT SIGNALING PATHWAY, SERINE/THREONINE-PROTEIN KINASE, RUTHENIUM GLYCOGEN SYNTHASE KINASE PICOMOLAR, NUCLEOTIDE-BINDING, KINASE, TRANSFERASE, ATP-BINDING, PHOSPHOPROTEIN
5ijq:A (ASP381) to (VAL447) CRYSTAL STRUCTURE OF AUTOTAXIN (ENPP2) RE-REFINED | HYDROLASE, LYSOPHOSPHATIDYLCHOLINE, SOMATOMEDIN, INFLAMMATION, METASTASIS, NEUROPATHIC PAIN, VASCULAR DEVELOPMENT, NEURAL DEVELOPMENT
5ijs:A (ILE382) to (VAL447) CRYSTAL STRUCTURE OF AUTOTAXIN WITH ORTHOVANADATE BOUND AS A TRIGONAL BIPYRAMIDAL INTERMEDIATE ANALOG | HYDROLASE, LYSOPHOSPHATIDYLCHOLINE, SOMATOMEDIN, INFLAMMATION, METASTASIS, NEUROPATHIC PAIN, VASCULAR DEVELOPMENT, NEURAL DEVELOPMENT
5ime:A (THR283) to (GLU345) CRYSTAL STRUCTURE OF P21-ACTIVATED KINASE 1 (PAK1) IN COMPLEX WITH COMPOUND 9 | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5ime:B (ASP332) to (LEU405) CRYSTAL STRUCTURE OF P21-ACTIVATED KINASE 1 (PAK1) IN COMPLEX WITH COMPOUND 9 | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5in3:B (ASP105) to (SER193) CRYSTAL STRUCTURE OF GLUCOSE-1-PHOSPHATE BOUND NUCLEOTIDYLATED HUMAN GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE | GALT, UMP-GALT, GLUCOSE-1-PHOSPHATE, GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE, TRANSFERASE
5in3:A (ASP105) to (SER192) CRYSTAL STRUCTURE OF GLUCOSE-1-PHOSPHATE BOUND NUCLEOTIDYLATED HUMAN GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE | GALT, UMP-GALT, GLUCOSE-1-PHOSPHATE, GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE, TRANSFERASE
4eqc:A (GLY282) to (GLU345) CRYSTAL STRUCTURE OF PAK1 KINASE DOMAIN IN COMPLEX WITH FRAX597 INHIBITOR | SERINE/THREONINE KINASE, PHOSPHORYLATION, ATP-BINDING, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3q4z:B (ASP332) to (LEU405) STRUCTURE OF UNPHOSPHORYLATED PAK1 KINASE DOMAIN | KINASE DOMAIN, SIGNALLING PATHWAY, TRANSFERASE
5ita:A (GLY469) to (GLN530) CRYSTAL STRUCTURE OF BRAF KINASE DOMAIN BOUND TO AZ-VEM | TRANSFERASE, KINASE AND INHIBITOR COMPLEX, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3q96:B (LYS473) to (GLN530) B-RAF KINASE DOMAIN IN COMPLEX WITH A TETRAHYDRONAPHTHALENE INHIBITOR | DESIGN, OPTIMIZATION, POTENT, ORALLY BIOAVAILABLE, TETRAHYDRONAPHTHALENE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3q9z:B (SER51) to (GLU114) CRYSTAL STRUCTURE OF HUMAN CK2 ALPHA IN COMPLEX WITH QUINALIZARIN AT PH 6.5 | PROTEIN KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3qa0:B (SER51) to (GLU114) CRYSTAL STRUCTURE OF THE APO-FORM OF HUMAN CK2 ALPHA AT PH 6.5 | PROTEIN KINASE, APO-FORM, TRANSFERASE
5j79:A (GLY30) to (GLU96) THE IDENTIFICATION AND PHARMACOLOGICAL CHARACTERIZATION OF 6-(TERT- BUTYLSULFONYL)-N-(5-FLUORO-1H-INDAZOL-3-YL)QUINOLIN-4-AMINE (GSK583), A HIGHLY POTENT AND SELECTIVE INHIBITOR OF RIP2 KINASE, COMPOUND 3 COMPLEX | KINASE DOMAIN, KINASE INHIBITOR, STRUCTURE-BASED DRUG DESIGN, INHIBITOR SELECTIVITY, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5j79:B (GLY30) to (GLU96) THE IDENTIFICATION AND PHARMACOLOGICAL CHARACTERIZATION OF 6-(TERT- BUTYLSULFONYL)-N-(5-FLUORO-1H-INDAZOL-3-YL)QUINOLIN-4-AMINE (GSK583), A HIGHLY POTENT AND SELECTIVE INHIBITOR OF RIP2 KINASE, COMPOUND 3 COMPLEX | KINASE DOMAIN, KINASE INHIBITOR, STRUCTURE-BASED DRUG DESIGN, INHIBITOR SELECTIVITY, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5j7b:A (GLY30) to (GLU96) THE IDENTIFICATION AND PHARMACOLOGICAL CHARACTERIZATION OF 6-(TERT- BUTYLSULFONYL)-N-(5-FLUORO-1H-INDAZOL-3-YL)QUINOLIN-4-AMINE (GSK583), A HIGHLY POTENT AND SELECTIVE INHIBITOR OF RIP2 KINASE, GSK583 COMPLEX | KINASE DOMAIN, KINASE INHIBITOR, STRUCTURE-BASED DRUG DESIGN, INHIBITOR SELECTIVITY, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5j7b:B (GLY30) to (GLU96) THE IDENTIFICATION AND PHARMACOLOGICAL CHARACTERIZATION OF 6-(TERT- BUTYLSULFONYL)-N-(5-FLUORO-1H-INDAZOL-3-YL)QUINOLIN-4-AMINE (GSK583), A HIGHLY POTENT AND SELECTIVE INHIBITOR OF RIP2 KINASE, GSK583 COMPLEX | KINASE DOMAIN, KINASE INHIBITOR, STRUCTURE-BASED DRUG DESIGN, INHIBITOR SELECTIVITY, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4fc0:A (GLY468) to (GLN529) CRYSTAL STRUCTURE OF HUMAN KINASE DOMAIN OF B-RAF WITH A DFG-OUT INHIBITOR | HUMAN SERINE/THERONINE PROTEIN KINASE, KINASE DRUG COMPLEX, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4fc0:B (LYS472) to (GLN529) CRYSTAL STRUCTURE OF HUMAN KINASE DOMAIN OF B-RAF WITH A DFG-OUT INHIBITOR | HUMAN SERINE/THERONINE PROTEIN KINASE, KINASE DRUG COMPLEX, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4v1a:l (TYR97) to (LYS150) STRUCTURE OF THE LARGE SUBUNIT OF THE MAMMALIAN MITOCHONDRIAL RIBOSOME, PART 2 OF 2 | RIBOSOME, TRANSLATION, LARGE RIBOSOMAL SUBUNIT, MITORIBOSOME, MAMMALIAN MITOCHONDRIAL RIBOSOME, CRYO-EM
3qqy:A (GLU178) to (LYS241) CRYSTAL STRUCTURE OF A NOVEL LAGLIDADG HOMING ENDONUCLEASE, I-ONUI (FROM OPHIOSTOMA NOVO-ULMI SUBSP. AMERICANA) | PROTEIN-DNA COMLEX, LAGLIDADG FAMILY, HYDROLASE, DNA BINDING, MITOCHONDRION, HYDROLASE-DNA COMPLEX
3qt1:K (LYS18) to (GLN76) RNA POLYMERASE II VARIANT CONTAINING A CHIMERIC RPB9-C11 SUBUNIT | TRANSFERASE-TRANSCRIPTION COMPLEX, RNA POLYMERASE II, TRANSCRIPTION, ELONGATION, MRNA CLEAVAGE, TRANSFERASE
3qtc:A (LYS321) to (MET391) CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF MMOMERS, AN O-METHYL TYROSYL-TRNA SYNTHETASE EVOLVED FROM METHANOSARCINA MAZEI PYLRS, COMPLEXED WITH O-METHYL TYROSINE AND AMP-PNP | PYRROLYSYL-TRNA SYNTHETASE, AMINOACYL-TRNA SYNTHETASE, ATP BINDING, O-METHYL TYROSINE BINDING, MAGNESIUM BINDING, AMINOACYLATION, ESTERIFICATION, LIGASE
3que:A (ASP88) to (ASP168) HUMAN P38 MAP KINASE IN COMPLEX WITH SKEPINONE-L | KINASE DOMAIN, PHOSPHATE TRANSFERASE, DIBENZOSUBERONE DERIVATIVE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4fgb:A (SER32) to (GLY100) CRYSTAL STRUCTURE OF HUMAN CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE I APO FORM | CAMK, CALMODULIN, AUTOINHIBITION, REGULATION MECHANISM, KINASE, TRANSFERASE
4fih:A (GLY333) to (MET395) CATALYTIC DOMAIN OF HUMAN PAK4 WITH QKFTGLPRQW PEPTIDE | SERINE/THREONINE-PROTEIN KINASE PAK4, KINASE DOMAIN, PROTEIN KINASE, ATP BINDING, PHOSPHORYLATION, TRANSFERASE
4fii:A (GLY333) to (MET395) CATALYTIC DOMAIN OF HUMAN PAK4 WITH RPKPLVDP PEPTIDE | SERINE/THREONINE-PROTEIN KINASE PAK4, KINASE DOMAIN, PROTEIN KINASE, ATP BINDING, PHOSPHORYLATION, TRANSFERASE-PEPTIDE COMPLEX
4fij:A (GLY333) to (MET395) CATALYTIC DOMAIN OF HUMAN PAK4 | SERINE/THREONINE-PROTEIN KINASE PAK4, KINASE DOMAIN, PROTEIN KINASE, ATP BINDING, PHOSPHORYLATION, TRANSFERASE
4fit:A (SER22) to (ALA104) FHIT-APO | HYDROLASE, FRAGILE HISTIDINE TRIAD PROTEIN, FHIT, PUTATIVE TUMOR SUPPRESSOR, HIT PROTEIN FAMILY, HISTIDINE TRIAD PROTEIN FAMILY, NUCLEOTIDYL HYDROLASE, NUCLEOTIDYL TRANSFERASE
4w8d:A (GLY36) to (ILE98) CRYSTAL STRUCTURE OF MST3 WITH A PYRROLOPYRIMIDINE INHIBITOR (PF- 06454589). | MST3, PYRROLOPYRIMIDINE, KINASE, INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4fm9:A (GLN906) to (THR973) HUMAN TOPOISOMERASE II ALPHA BOUND TO DNA | TOPOISOMERASE, DNA-BINDING, PROTEIN-DNA COMPLEX, ISOMERASE-DNA COMPLEX
3rep:A (GLY210) to (HIS270) CRYSTAL STRUCTURE OF THE ILK/ALPHA-PARVIN CORE COMPLEX (MNATP) | CELL ADHESION, ANK REPEAT, ATP-BINDING, CELL JUNCTION, CELL MEMBRANE, INTEGRIN-BINDING PROTEIN, MEMBRANE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, PSEUDOKINASE, ACTIN-BINDING, CYTOSKELETON
4fsz:A (GLY21) to (PHE83) CRYSTAL STRUCTURE OF THE CHK1 | TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ft0:A (GLY21) to (PHE83) CRYSTAL STRUCTURE OF THE CHK1 | TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ft7:A (GLY21) to (PHE83) CRYSTAL STRUCTURE OF THE CHK1 | TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ftn:A (GLU22) to (PHE83) CRYSTAL STRUCTURE OF THE CHK1 | TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3ri6:B (LYS300) to (ILE392) A NOVEL MECHANISM OF SULFUR TRANSFER CATALYZED BY O-ACETYLHOMOSERINE SULFHYDRYLASE IN METHIONINE BIOSYNTHETIC PATHWAY OF WOLINELLA SUCCINOGENES | WOLINELLA SUCCINOGENES O-ACETYLHOMOSERINE SULFHYDRYLASE, PYRIDOXAL- 5'-PHOSPHATE, GAMMA-ELIMINATION, DIRECT SULFHYDRYLATION, CYS/MET METABOLISM, O-ACETYLHOMOSERINE, PROTEIN THIOCARBOXYLATE, TRANSFERASE
5jrv:A (GLY111) to (LYS179) CRYSTAL STRUCTURE OF FE(II) NO-BOUND H-NOX PROTEIN FROM C. SUBTERRANEUS | HEME-BASED METHYL-ACCEPTING CHEMOTAXIS PROTEIN GAS BINDING SIGNALING PROTEIN, SIGNALING PROTEIN
5jrx:A (GLY111) to (LYS179) CRYSTAL STRUCTURE OF FE(II) CO-BOUND H-NOX PROTEIN FROM C. SUBTERRANEUS | HEME-BASED METHYL-ACCEPTING CHEMOTAXIS PROTEIN, GAS BINDING, SIGNALING PROTEIN
5jt2:A (GLY518) to (ASP594) BRAFV600E KINASE DOMAIN IN COMPLEX WITH CHEMICALLY LINKED VEMURAFENIB INHIBITOR VEM-BISAMIDE | KINASE, DIMER, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4fzd:B (GLU37) to (GLY104) CRYSTAL STRUCTURE OF MST4-MO25 COMPLEX WITH WSF MOTIF | SCAFFOLD PROTEIN, PROTEIN SER/THR KINASE, ATP BINDING, SIGNALING PROTEIN-TRANSFERASE COMPLEX
5jvo:A (SER97) to (LEU142) CRYSTAL STRUCTURE OF THE ARGININE REPRESSOR FROM THE PATHOGENIC BACTERIUM CORYNEBACTERIUM PSEUDOTUBERCULOSIS | ARGININE REPRESSOR, DNA BINDING PROTEIN
5jvo:B (SER97) to (LEU142) CRYSTAL STRUCTURE OF THE ARGININE REPRESSOR FROM THE PATHOGENIC BACTERIUM CORYNEBACTERIUM PSEUDOTUBERCULOSIS | ARGININE REPRESSOR, DNA BINDING PROTEIN
4g1h:A (GLY108) to (HIS156) GROUP B STREPTOCOCCUS PILUS ISLAND 1 SORTASE C2 | CYSTEINE PROTEASE, EXTRACELLULAR, TRANSFERASE
5k1p:A (LYS321) to (HIS392) CATALYTIC DOMAIN OF POLYSPECIFIC PYRROLYSYL-TRNA SYNTHETASE MUTANT N346A/C348A IN COMPLEX WITH AMPPNP | PROTEIN ENGINEERING, AMINOACYL-TRNA SYNTHETASE, NONCANONICAL AMINO ACIDS, LIGASE
5k1x:A (PRO319) to (HIS392) CATALYTIC DOMAIN OF POLYSPECIFIC PYRROLYSYL-TRNA SYNTHETASE MUTANT Y306A/N346A/C348A/Y384F IN COMPLEX WITH AMPPNP | PROTEIN ENGINEERING, AMINOACYL-TRNA SYNTHETASE, NONCANONICAL AMINO ACIDS, LIGASE
5kbq:A (GLY282) to (GLU345) PAK1 IN COMPLEX WITH BIS-ANILINO PYRIMIDINE INHIBITOR | SERINE/THREONINE-PROTEIN KINASE PAK1, KINASE, TRANSFERASE
5kbq:B (ASP332) to (LEU405) PAK1 IN COMPLEX WITH BIS-ANILINO PYRIMIDINE INHIBITOR | SERINE/THREONINE-PROTEIN KINASE PAK1, KINASE, TRANSFERASE
5l0b:A (ILE382) to (ASP448) CRYSTAL STRUCTURE OF AUTOTAXIN AND COMPOUND 1 | PHOSPHOLIPASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5l0b:B (ILE382) to (ASP448) CRYSTAL STRUCTURE OF AUTOTAXIN AND COMPOUND 1 | PHOSPHOLIPASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5l0e:A (ILE382) to (ASP448) CRYSTAL STRUCTURE OF AUTOTAXIN AND COMPOUND 1 | PHOSPHOLIPASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5l0e:B (ILE382) to (ASP448) CRYSTAL STRUCTURE OF AUTOTAXIN AND COMPOUND 1 | PHOSPHOLIPASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5l0k:B (ILE382) to (ASP448) CRYSTAL STRUCTURE OF AUTOTAXIN AND COMPOUND PF-8380 | PHOSPHOLIPASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
5lia:A (ASP381) to (VAL447) CRYSTAL STRUCTURE OF MURINE AUTOTAXIN IN COMPLEX WITH A SMALL MOLECULE INHIBITOR | LYSOPHOSPHOLIPASE D, AUTOTAXIN, ENPP2, HYDROLASE
5lpb:A (GLY895) to (GLU957) CRYSTAL STRUCTURE OF THE BRI1 KINASE DOMAIN (865-1160) IN COMPLEX WITH ADP FROM ARABIDOPSIS THALIANA | BRASSINOSTEROID RECEPTOR, KINASE DOMAIN, DUAL-SPECIFICIFY KINASE, MEMBRANE RECEPTOR KINASE, PLASMA MEMBRANE, TRANSFERASE
5lpv:A (GLY895) to (GLU957) CRYSTAL STRUCTURE OF THE BRI1 KINASE DOMAIN (865-1160) IN COMPLEX WITH AMPPNP AND MN FROM ARABIDOPSIS THALIANA | BRASSINOSTEROID RECEPTOR, KINASE DOMAIN, DUAL-SPECIFICIFY KINASE, MEMBRANE RECEPTOR KINASE, PLASMA MEMBRANE, TRANSFERASE
5t5i:A (HIS301) to (VAL349) TUNGSTEN-CONTAINING FORMYLMETHANOFURAN DEHYDROGENASE FROM METHANOTHERMOBACTER WOLFEII, ORTHORHOMBIC FORM AT 1.9 A | CO2 FIXATION, METALLOHYDROLASE, FORMATE DEHYDROGENASE, TUNGSTOPTERIN, METHANOGENESIS, GREEN HOUSE GAS, METHANOTHERMOBACTER WOLFEII, IRON SULFUR CLUSTER, FERREDOXIN, BETA HELICOIDAL, CHANNEL, FORMATE, CO2, METHANOFURAN, FORMYLMETHANOFURAN, NANOMACHINE, BINUCLEAR CENTER, TUNGSTEN, GATE, COUPLING, ENZYME, ANAEROBIC, CARBOXYLYSINE, OXIDOREDUCTASE
5t5i:I (HIS301) to (VAL349) TUNGSTEN-CONTAINING FORMYLMETHANOFURAN DEHYDROGENASE FROM METHANOTHERMOBACTER WOLFEII, ORTHORHOMBIC FORM AT 1.9 A | CO2 FIXATION, METALLOHYDROLASE, FORMATE DEHYDROGENASE, TUNGSTOPTERIN, METHANOGENESIS, GREEN HOUSE GAS, METHANOTHERMOBACTER WOLFEII, IRON SULFUR CLUSTER, FERREDOXIN, BETA HELICOIDAL, CHANNEL, FORMATE, CO2, METHANOFURAN, FORMYLMETHANOFURAN, NANOMACHINE, BINUCLEAR CENTER, TUNGSTEN, GATE, COUPLING, ENZYME, ANAEROBIC, CARBOXYLYSINE, OXIDOREDUCTASE
5t5m:A (HIS301) to (VAL349) TUNGSTEN-CONTAINING FORMYLMETHANOFURAN DEHYDROGENASE FROM METHANOTHERMOBACTER WOLFEII, TRIGONAL FORM AT 2.5 A. | CO2 FIXATION, METALLOHYDROLASE, FORMATE DEHYDROGENASE, TUNGSTOPTERIN, METHANOGENESIS, GREEN HOUSE GAS, METHANOTHERMOBACTER WOLFEII, IRON SULFUR CLUSTER, FERREDOXIN, BETA HELICOIDAL, CHANNEL, FORMATE, CO2, METHANOFURAN, FORMYLMETHANOFURAN, NANOMACHINE, BINUCLEAR CENTER, TUNGSTEN, GATE, COUPLING, ENZYME, ANAEROBIC, CARBOXYLYSINE, OXIDOREDUCTASE
3rse:D (ASP149) to (PRO229) STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF TWO BINDING SITES FOR NUCLEATION PROMOTING FACTOR WASP-VCA ON ARP2/3 COMPLEX | HETEROHEPTAMER, HEPTAMERIC HETEROCOMPLEX, F-ACTIN BRANCH INITIATION, ACTIN, CYTOSOL, STRUCTURAL PROTEIN
3s2h:K (LYS18) to (THR78) RNA POLYMERASE II INITIATION COMPLEX WITH A 6-NT RNA CONTAINING A 2[PRIME]-IODO ATP | RNA POLYMERASE II, INITIATION COMPLEX, TRANSCRIPTION-RNA-DNA COMPLEX
2p9p:D (ASP149) to (PRO229) CRYSTAL STRUCTURE OF BOVINE ARP2/3 COMPLEX CO-CRYSTALLIZED WITH ADP | ACTIN, WD REPEAT,COMPLEX, STRUCTURAL PROTEIN
2bik:B (GLY50) to (ILE119) HUMAN PIM1 PHOSPHORYLATED ON SER261 | KINASE, CANCER, LEUKEMIA, TRANSFERASE, ATP-BINDING
3fi3:A (ASN128) to (ASP207) CRYSTAL STRUCTURE OF JNK3 WITH INDAZOLE INHIBITOR, SR-3737 | JNK3, PROTEIN-INHIBITOR COMPLEX, ALTERNATIVE SPLICING, ATP- BINDING, CHROMOSOMAL REARRANGEMENT, CYTOPLASM, EPILEPSY, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
3fn7:A (ILE95) to (GLY146) CRYSTAL STRUCTURE OF SORTASE A (SPY1154) FROM STREPTOCOCCUS PYOGENES SEROTYPE M1 STRAIN SF370 | SORTASE-FOLD, HYDROLASE
3ftb:D (LYS290) to (ASP343) THE CRYSTAL STRUCTURE OF THE HISTIDINOL-PHOSPHATE AMINOTRANSFERASE FROM CLOSTRIDIUM ACETOBUTYLICUM | HISTIDINOL-PHOSPHATE AMINOTRANSFERASE, STRUCTURAL GENOMICS, PSI, MCSG, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, AMINOTRANSFERASE, TRANSFERASE
2q7h:A (LYS321) to (HIS392) PYRROLYSYL-TRNA SYNTHETASE BOUND TO ADENYLATED PYRROLYSINE AND PYROPHOSPHATE | PYRROLYSYL-TRNA SYNTHETASE, PYRROLYSINE, LIGASE
2cjh:A (ASP381) to (PRO426) LYSINE AMINOTRANSFERASE FROM M. TUBERCULOSIS IN THE INTERNAL ALDIMINE FORM WITH BOUND SUBSTRATE 2- KETOGLUTARATE | TRANSFERASE, INTERNAL ALDIMINE, RV3290C, AMINOTRANSFERASE
2ckp:B (LEU124) to (GLN207) CRYSTAL STRUCTURE OF HUMAN CHOLINE KINASE ALPHA-2 IN COMPLEX WITH ADP | KINASE, TRANSFERASE, CHOLINE KINASE, PHOSPHATYDILCHOLINE
3t1o:A (SER2) to (LEU60) MGLA BOUND TO GDP | G DOMAIN CONTAINING PROTEIN, BACTERIAL GTPASE, BACTERIAL POLARITY, MOTILITY, POLE LOCALISATION, ALPHA/BETA PROTEIN, HYDROLASE
4xtz:B (VAL56) to (ARG135) MYCOBACTERIUM TUBERCULOSIS BIOTIN LIGASE COMPLEXED WITH BISUBSTRATE INHIBITOR 69 THAT HAS A FLUORINE IN PLACE OF THE RIBOSE 2'OH | BIOTIN-PROTEIN LIGASE, BISUBSTRATE INHIBITOR, LIGASE-LIGASE INHIBITOR COMPLEX
4it2:A (GLY111) to (ASN180) MN(III)-PPIX BOUND TT H-NOX | O2-SENSING HEME DOMAIN, OXYGEN BINDING
3git:A (GLY364) to (SER431) CRYSTAL STRUCTURE OF A TRUNCATED ACETYL-COA SYNTHASE | ACETYLTRANSFERASE, CARBON DIOXIDE FIXATION, IRON, IRON-SULFUR, METAL- BINDING, NICKEL, TRANSFERASE
3git:B (GLY364) to (SER431) CRYSTAL STRUCTURE OF A TRUNCATED ACETYL-COA SYNTHASE | ACETYLTRANSFERASE, CARBON DIOXIDE FIXATION, IRON, IRON-SULFUR, METAL- BINDING, NICKEL, TRANSFERASE
3git:C (GLY364) to (SER431) CRYSTAL STRUCTURE OF A TRUNCATED ACETYL-COA SYNTHASE | ACETYLTRANSFERASE, CARBON DIOXIDE FIXATION, IRON, IRON-SULFUR, METAL- BINDING, NICKEL, TRANSFERASE
3git:E (LYS365) to (SER431) CRYSTAL STRUCTURE OF A TRUNCATED ACETYL-COA SYNTHASE | ACETYLTRANSFERASE, CARBON DIOXIDE FIXATION, IRON, IRON-SULFUR, METAL- BINDING, NICKEL, TRANSFERASE
3git:F (LYS365) to (SER431) CRYSTAL STRUCTURE OF A TRUNCATED ACETYL-COA SYNTHASE | ACETYLTRANSFERASE, CARBON DIOXIDE FIXATION, IRON, IRON-SULFUR, METAL- BINDING, NICKEL, TRANSFERASE
1py5:A (GLY222) to (ASP281) CRYSTAL STRUCTURE OF TGF-BETA RECEPTOR I KINASE WITH INHIBITOR | TGF-BETA, RECEPTOR I, KINASE, TRANSFERASE
1q5f:A (GLY96) to (GLY181) NMR STRUCTURE OF TYPE IVB PILIN (PILS) FROM SALMONELLA TYPHI | TYPE IVB PILIN, ALPHA-BETA ROLL, MONOMER, CELL ADHESION
3tkh:A (GLY21) to (PHE83) CRYSTAL STRUCTURE OF CHK1 IN COMPLEX WITH INHIBITOR S01 | CHK1, KINASE, CELL CHECKPOINT, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4jdh:A (ILE334) to (MET395) CRYSTAL STRUCTURE OF SERINE/THREONINE-PROTEIN KINASE PAK 4 IN COMPLEX WITH PAKTIDE T PEPTIDE SUBSTRATE | TRANSFERASE-PEPTIDE COMPLEX, TRANSFERASE/PEPTIDE, SERINE/THREONINE- PROTEIN KINASE PAK4, ATP BINDING, PHOSPHORYLATION
2e9p:A (GLU22) to (PHE83) STRUCTURE OF H-CHK1 COMPLEXED WITH A771129 | PROTEIN-INHIBITOR COMPLEX, TRANSFERASE
1qxo:A (MSE1) to (ILE77) CRYSTAL STRUCTURE OF CHORISMATE SYNTHASE COMPLEXED WITH OXIDIZED FMN AND EPSP | BETA-ALPHA-BETA, FLAVOPROTEIN, SHIKIMATE, ANTI-INFECTIVE, LYASE
1f9n:A (LYS86) to (ILE131) CRYSTAL STRUCTURE OF AHRC, THE ARGININE REPRESSOR/ACTIVATOR PROTEIN FROM BACILLUS SUBTILIS | WINGED-HELIX-TURN-HELIX, ARGININE REPRESSOR, DNA BINDING PROTEIN
1f9n:C (LYS86) to (ILE131) CRYSTAL STRUCTURE OF AHRC, THE ARGININE REPRESSOR/ACTIVATOR PROTEIN FROM BACILLUS SUBTILIS | WINGED-HELIX-TURN-HELIX, ARGININE REPRESSOR, DNA BINDING PROTEIN
1f9n:E (LYS86) to (ILE131) CRYSTAL STRUCTURE OF AHRC, THE ARGININE REPRESSOR/ACTIVATOR PROTEIN FROM BACILLUS SUBTILIS | WINGED-HELIX-TURN-HELIX, ARGININE REPRESSOR, DNA BINDING PROTEIN
2v3j:A (GLN111) to (VAL162) THE YEAST RIBOSOME SYNTHESIS FACTOR EMG1 ALPHA BETA KNOT FOLD METHYLTRANSFERASE | EMG1, RRNA PROCESSING, NUCLEAR PROTEIN, RIBONUCLEOPROTEIN, RIBOSOME BIOGENESIS, ALPHA/BETA KNOT FOLD METHYLTRANSFERASE, RIBOSOMAL PROTEIN
2v3k:A (GLN111) to (VAL162) THE YEAST RIBOSOME SYNTHESIS FACTOR EMG1 ALPHA BETA KNOT FOLD METHYLTRANSFERASE | RIBOSOMAL PROTEIN, EMG1, RRNA PROCESSING, NUCLEAR PROTEIN, RIBONUCLEOPROTEIN, RIBOSOME BIOGENESIS, ALPHA/BETA KNOT FOLD METHYLTRANSFERASE
3uku:D (ASP149) to (PRO229) STRUCTURE OF ARP2/3 COMPLEX WITH BOUND INHIBITOR CK-869 | BETA-PROPELLER, STRUCTURAL PROTEIN, ACTIN NUCLEATION FACTOR
2f7q:A (MET962) to (ALA1038) GOLGI ALPHA-MANNOSIDASE II COMPLEX WITH AMINOCYCLOPENTITETROL | GLYCOSYL HYDROLASE FAMILY 38, HYDROLASE
4z1z:B (ASP179) to (ASN241) CRYSTAL STRUCTURE OF MEGANUCLEASE I-SMAMI BOUND TO UNCLEAVEABLE DNA WITH A TTCT CENTRAL FOUR | HYDROLASE-DNA COMPLEX, LAGLIDADG, HOMING ENDONUCLEASE, MEGANUCLEASE
3hrb:A (SER37) to (HIS107) P38 KINASE CRYSTAL STRUCTURE IN COMPLEX WITH SMALL MOLECULE INHIBITOR | P38 MAP KINASE, TRANSFERASE, INHIBITOR COMPLEX, ALTERNATIVE SPLICING, ATP-BINDING, CYTOPLASM, KINASE, NUCLEOTIDE- BINDING, NUCLEUS, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE
2fqm:E (GLN110) to (LYS170) CRYSTAL STRUCTURE OF THE OLIGOMERIZATION DOMAIN OF THE PHOSPHOPROTEIN OF VESICULAR STOMATITIS VIRUS | NEGATIVE STRAND RNA VIRUS, POLYMERASE, REPLICATION, COFACTOR, VIRAL PROTEIN
4zg7:A (ASP382) to (VAL448) STRUCTURAL BASIS FOR INHIBITION OF HUMAN AUTOTAXIN BY FOUR NOVEL COMPOUNDS | AUTOTAXIN, ENPP2, INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3i5t:B (GLU374) to (PRO428) CRYSTAL STRUCTURE OF AMINOTRANSFERASE PRK07036 FROM RHODOBACTER SPHAEROIDES KD131 | AMINOTRANSFERASE, PYRIDOXAL 5'-PHOSPHATE, PSI-2, NYSGXRC, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, PYRIDOXAL PHOSPHATE, TRANSFERASE
2vwb:B (ASP346) to (MET413) STRUCTURE OF THE ARCHAEAL KAE1-BUD32 FUSION PROTEIN MJ1130: A MODEL FOR THE EUKARYOTIC EKC-KEOPS SUBCOMPLEX INVOLVED IN TRANSCRIPTION AND TELOMERE HOMEOSTASIS. | HYDROLASE, EKC, KAE1, BUD32, KEOPS, MJ1130, PROTEASE, TELOMERE, METALLOPROTEASE
2ghg:A (GLY21) to (LEU84) H-CHK1 COMPLEXED WITH A431994 | PROTEIN-INHIBITOR COMPLEX, TRANSFERASE
2w7x:A (GLU233) to (VAL300) CELLULAR INHIBITION OF CHECKPOINT KINASE 2 AND POTENTIATION OF CYTOTOXIC DRUGS BY NOVEL CHK2 INHIBITOR PV1019 | CO-CRYSTAL STRUCTURE, KINASE, NUCLEUS, MAGNESIUM, CELL CYCLE, ATP-BINDING, LI-FRAUMENI SYNDROME, SERINE/THREONINE-PROTEIN KINASE, DISEASE MUTATION, NUCLEOTIDE-BINDING, TRANSFERASE, POTENTIATION, METAL-BINDING, PROTO-ONCOGENE, PHOSPHOPROTEIN, CHK2 INHIBITOR
1til:A (VAL64) to (SER141) CRYSTAL STRUCTURES OF THE ADP AND ATP BOUND FORMS OF THE BACILLUS ANTI-SIGMA FACTOR SPOIIAB IN COMPLEX WITH THE ANTI-ANTI-SIGMA SPOIIAA:POISED FOR PHOSPHORYLATION COMPLEX WITH ATP, CRYSTAL FORM II | SPOIIAB, SPOIIA, ANTI-SIGMA, ANTI-ANTI-SIGMA, SPORULATION, SERINE KINASEA, TRANSCRIPTION
3vnq:A (LEU402) to (TYR464) CO-CRYSTAL STRUCTURE OF NRPS ADENYLATION PROTEIN CYTC1 WITH ATP FROM STREPTOMYCES | LIGASE, ADENYLATION, ATP-BINDING, NON-RIBOSOMAL PEPTIDE SYNTHESE, NRPS, STREPTOMYCES
4zy6:A (GLY282) to (MET344) CRYSTAL STRUCTURE OF P21-ACTIVATED KINASE 1 IN COMPLEX WITH AN INHIBITOR COMPOUND 29 | PAK1, KINASE, INHIBITOR, COMPLEX, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3vqw:A (LYS321) to (HIS392) CRYSTAL STRUCTURE OF THE SEMET SUBSTITUTED CATALYTIC DOMAIN OF PYRROLYSYL-TRNA SYNTHETASE | STRUCTURAL GENOMICS, NPPSFA, NATIONAL PROJECT ON PROTEIN STRUCTURAL AND FUNCTIONAL ANALYSES, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, AMINOACYL-TRNA SYNTHETASE, PYRROLYSYL-TRNA SYNTHETASE, AMPPNP, LIGASE
2wmx:A (GLU22) to (PHE83) CRYSTAL STRUCTURE OF CHECKPOINT KINASE 1 (CHK1) IN COMPLEX WITH INHIBITORS | SERINE/THREONINE-PROTEIN KINASE, POLYMORPHISM, PHOSPHOPROTEIN, UBL CONJUGATION, ISOPEPTIDE BOND, CHECKPOINT KINASE, NUCLEOTIDE-BINDING, SERINE/THREONINE KINASE, DNA DAMAGE, DNA REPAIR, ATP-BINDING, TRANSFERASE, CHK1, KINASE, NUCLEUS, CYTOPLASM, CELL CYCLE
1u4h:A (GLY111) to (LYS179) CRYSTAL STRUCTURE OF AN OXYGEN BINDING H-NOX DOMAIN RELATED TO SOLUBLE GUANYLATE CYCLASES (OXYGEN COMPLEX) | H-NOX DOMAIN, HEME, OXYGEN SENSOR, SIGNAL TRANSDUCTION, CHEMOTAXIS, SIGNALING PROTEIN
1u4h:B (GLY111) to (LYS179) CRYSTAL STRUCTURE OF AN OXYGEN BINDING H-NOX DOMAIN RELATED TO SOLUBLE GUANYLATE CYCLASES (OXYGEN COMPLEX) | H-NOX DOMAIN, HEME, OXYGEN SENSOR, SIGNAL TRANSDUCTION, CHEMOTAXIS, SIGNALING PROTEIN
1u56:A (GLY111) to (LYS179) CRYSTAL STRUCTURE OF AN OXYGEN BINDING H-NOX DOMAIN RELATED TO SOLUBLE GUANYLATE CYCLASES (WATER-LIGATED, FERRIC FORM) | H-NOX DOMAIN, HEME, OXYGEN SENSOR, SIGNAL TRANSDUCTION, CHEMOTAXIS, SIGNALING PROTEIN
1u56:B (GLY111) to (LYS179) CRYSTAL STRUCTURE OF AN OXYGEN BINDING H-NOX DOMAIN RELATED TO SOLUBLE GUANYLATE CYCLASES (WATER-LIGATED, FERRIC FORM) | H-NOX DOMAIN, HEME, OXYGEN SENSOR, SIGNAL TRANSDUCTION, CHEMOTAXIS, SIGNALING PROTEIN
2hy8:1 (GLY282) to (VAL343) PAK1 COMPLEX WITH ST2001 | TYPICAL FOLD OF SER/THR KINASES. INHIBITOR IS BOUND BETWEEN THE N-TERMINAL AND C-TERMINAL DOMAINS., TRANSFERASE
2wti:A (GLU233) to (VAL300) CRYSTAL STRUCTURE OF CHK2 IN COMPLEX WITH AN INHIBITOR | TRANSFERASE, KINASE, CELL CYCLE, LI-FRAUMENI SYNDROME
2wtj:A (GLU233) to (VAL300) CRYSTAL STRUCTURE OF CHK2 IN COMPLEX WITH AN INHIBITOR | TRANSFERASE, KINASE, CELL CYCLE, LI-FRAUMENI SYNDROME
4m97:A (GLY62) to (GLY127) CALCIUM-DEPENDENT PROTEIN KINASE 1 FROM NEOSPORA CANINUM | SERINE/THREONINE PROTEIN KINASE, TRANSFERASE, CALCIUM-BINDING, ATP- BINDING
2x0g:A (PHE24) to (GLU94) X-RAY STRUCTURE OF A DAP-KINASE CALMODULIN COMPLEX | TRANSFERASE-SIGNALING PROTEIN COMPLEX, TRANSFERASE SIGNALING PROTEIN COMPLEX, PHOSPHOPROTEIN, CALMODULIN-BINDING, DAPK, KINASE, ANK REPEAT, CALMODULIN, TRANSFERASE, ATP-BINDING
4md7:E (SER51) to (GLU114) CRYSTAL STRUCTURE OF FULL-LENGTH SYMMETRIC CK2 HOLOENZYME | PROTEIN SERINE/THREONINE KINASE, TRANSFERASE
4md7:F (SER51) to (GLU114) CRYSTAL STRUCTURE OF FULL-LENGTH SYMMETRIC CK2 HOLOENZYME | PROTEIN SERINE/THREONINE KINASE, TRANSFERASE
4md7:G (SER51) to (GLU114) CRYSTAL STRUCTURE OF FULL-LENGTH SYMMETRIC CK2 HOLOENZYME | PROTEIN SERINE/THREONINE KINASE, TRANSFERASE
4md7:H (SER51) to (GLU114) CRYSTAL STRUCTURE OF FULL-LENGTH SYMMETRIC CK2 HOLOENZYME | PROTEIN SERINE/THREONINE KINASE, TRANSFERASE
1vde:A (ASP326) to (GLY388) PI-SCEI, A HOMING ENDONUCLEASE WITH PROTEIN SPLICING ACTIVITY | HOMING ENDONUCLEASE, PROTEIN SPLICING
1vde:B (ASP326) to (GLY388) PI-SCEI, A HOMING ENDONUCLEASE WITH PROTEIN SPLICING ACTIVITY | HOMING ENDONUCLEASE, PROTEIN SPLICING
2xrg:A (ILE382) to (ASP448) CRYSTAL STRUCTURE OF AUTOTAXIN (ENPP2) IN COMPLEX WITH THE HA155 BORONIC ACID INHIBITOR | HYDROLASE, LYSOPHOSPHATIDIC ACID, LPA, LYSOPHOSPHATIDYLCHOLINE, LPC, SOMATOMEDIN, METASTASIS, NEUROPATHIC PAIN, VASCULAR DEVELOPMENT, NEURAL DEVELOPMENT
1k0g:A (PHE260) to (ALA346) THE CRYSTAL STRUCTURE OF AMINODEOXYCHORISMATE SYNTHASE FROM PHOSPHATE GROWN CRYSTALS | AMINODEOXYCHORISMATE SYNTHASE, CHORISMATE, GLUTAMINE, TRYPTOPHAN, PABA SYNTHASE, P-AMINOBENZOATE SYNTHASE, LYASE
1k0g:B (PHE260) to (ALA346) THE CRYSTAL STRUCTURE OF AMINODEOXYCHORISMATE SYNTHASE FROM PHOSPHATE GROWN CRYSTALS | AMINODEOXYCHORISMATE SYNTHASE, CHORISMATE, GLUTAMINE, TRYPTOPHAN, PABA SYNTHASE, P-AMINOBENZOATE SYNTHASE, LYASE
3jay:A (ASP160) to (TYR221) ATOMIC MODEL OF TRANSCRIBING CYTOPLASMIC POLYHEDROSIS VIRUS | VIRAL ATPASE, HISTIDINE-MEDIATED GUANYLYL TRANSFER, CONFORMATIONAL CHANGES, REGULATION OF TRANSCRIPTION, VIRUS
2y0s:C (SER155) to (ASN212) CRYSTAL STRUCTURE OF SULFOLOBUS SHIBATAE RNA POLYMERASE IN P21 SPACE GROUP | TRANSFERASE, NUCLEOTIDYLTRANSFERASE, TRANSCRIPTION, METAL-BINDING
1wih:A (GLY26) to (ILE74) SOLUTION STRUCTURE OF RSGI RUH-021, A DOMAIN II OF RIBOSOME RECYCLING FACTOR FROM MOUSE CDNA | RIBOSOME RECYCLING FACTOR, STRUCTURAL GENOMICS, RIKEN STRUCTURAL GENOMICS/PROTEOMICS INITIATIVE, RSGI, UNKNOWN FUNCTION
4njy:A (CYS75) to (GLY154) HUMAN HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN 2 (HHINT2) IN H32 SPACE GROUP AT 1.32 A | HINT, HISTIDINE TRIAD, HIT, PHOSPHORAMIDASE, HYDROLASE, DNA BINDING PROTEIN
2yer:A (GLY21) to (PHE83) SYNTHESIS AND EVALUATION OF TRIAZOLONES AS CHECKPOINT KINASE 1 INHIBITORS | TRANSFERASE
2yex:A (GLY21) to (PHE83) SYNTHESIS AND EVALUATION OF TRIAZOLONES AS CHECKPOINT KINASE 1 INHIBITORS | TRANSFERASE, CELL CYCLE, CHK
1kut:A (THR7) to (VAL74) STRUCTURAL GENOMICS, PROTEIN TM1243, (SAICAR SYNTHETASE) | STRUCTURAL GENOMICS, SAICAR SYNTHETASE, PSI, PROTEIN STRUCTURE INITIATIVE, MIDWEST CENTER FOR STRUCTURAL GENOMICS, MCSG, LIGASE
2ym6:A (GLY21) to (PHE83) CRYSTAL STRUCTURE OF CHECKPOINT KINASE 1 (CHK1) IN COMPLEX WITH INHIBITORS | TRANSFERASE, DNA REPAIR, CELL CYCLE
1l5i:A (PHE7) to (GLU65) 30-CONFORMER NMR ENSEMBLE OF THE N-TERMINAL, DNA-BINDING DOMAIN OF THE REPLICATION INITIATION PROTEIN FROM A GEMINIVIRUS (TOMATO YELLOW LEAF CURL VIRUS-SARDINIA) | A+B FOLD, RBD-LIKE FOLD, VIRAL PROTEIN
2o09:B (ALA119) to (GLU182) CRYSTAL STRUCTURE OF THE H-NOX DOMAIN FROM NOSTOC SP. PCC 7120 | HEME, NO, CO, GUANYLYL CYCLASE, SIGNALING PROTEIN
2o0c:B (GLN114) to (GLU182) CRYSTAL STRUCTURE OF THE H-NOX DOMAIN FROM NOSTOC SP. PCC 7120 COMPLEXED TO NO | HEME, NO, CO, GUANYLYL CYCLASE, SIGNALING PROTEIN
2o12:A (ARG3) to (GLY78) MYCOBACTERIUM TUBERCULOSIS CHORISMATE SYNTHASE IN COMPLEX WITH FMN | SHIKIMATE PATHWAY, M. TUBERCULOSIS, CHORISMATE SYNTHASE, LYASE
4a72:A (ASP372) to (PRO427) CRYSTAL STRUCTURE OF THE OMEGA TRANSAMINASE FROM CHROMOBACTERIUM VIOLACEUM IN A MIXTURE OF APO AND PLP-BOUND STATES | TRANSFERASE, PLP-BINDING ENZYME, TRANSAMINASE FOLD TYPE I
1xpp:A (ILE14) to (VAL67) CRYSTAL STRUCTURE OF TA1416,DNA-DIRECTED RNA POLYMERASE SUBUNIT L, FROM THERMOPLASMA ACIDOPHILUM | STRUCTURAL GENOMICS, DNA-DIRECTED RNA POLYMERASE, THERMOPLASMA ACIDOPHILUM, PROTEIN STRUCTURE INITIATIVE, MCSG, MIDWEST CENTER FOR STRUCTURAL GENOMICS, PSI, TRANSFERASE
1xpp:C (ILE14) to (VAL67) CRYSTAL STRUCTURE OF TA1416,DNA-DIRECTED RNA POLYMERASE SUBUNIT L, FROM THERMOPLASMA ACIDOPHILUM | STRUCTURAL GENOMICS, DNA-DIRECTED RNA POLYMERASE, THERMOPLASMA ACIDOPHILUM, PROTEIN STRUCTURE INITIATIVE, MCSG, MIDWEST CENTER FOR STRUCTURAL GENOMICS, PSI, TRANSFERASE
3kc3:K (LEU79) to (GLU139) MK2 COMPLEXED TO INHIBITOR N4-(7-(BENZOFURAN-2-YL)-1H-INDAZOL-5-YL) PYRIMIDINE-2,4-DIAMINE | MAPKAP-K2, MK2, TNFALPHA, DIAMINOPYRIMIDINE, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
5ctp:B (GLU55) to (GLU114) CRYSTAL STRUCTURE OF CK2ALPHA WITH N-(3-(3-CHLORO-4-(PHENYL) BENZYLAMINO)PROPYL)ACETAMIDE BOUND | CK2ALPHA, CK2A, FRAGMENT BASED DRUG DISCOVERY, HIGH CONCENTRATION SCREENING, SELECTIVE ATP COMPETITIVE INHIBITORS, SURFACE ENTROPHY REDUCTION, TRANSFERASE
3khx:A (ASP203) to (LYS266) CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS METALLOPEPTIDASE (SAPEP/DAPE) IN THE APO-FORM | DIPEPTIDASE, DAPE, METALLOPEPTIDASE, HYDROLASE, METAL-BINDING, METALLOPROTEASE, PROTEASE
3khx:B (ASP203) to (HIS269) CRYSTAL STRUCTURE OF STAPHYLOCOCCUS AUREUS METALLOPEPTIDASE (SAPEP/DAPE) IN THE APO-FORM | DIPEPTIDASE, DAPE, METALLOPEPTIDASE, HYDROLASE, METAL-BINDING, METALLOPROTEASE, PROTEASE
3kvx:A (GLY76) to (GLU147) JNK3 BOUND TO AMINOPYRIMIDINE INHIBITOR, SR-3562 | JNK3, MAPK10, INHIBITOR, ATP-BINDING, EPILEPSY, KINASE, NUCLEOTIDE- BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE
5dey:A (GLY282) to (GLU345) CRYSTAL STRUCTURE OF PAK1 IN COMPLEX WITH AN INHIBITOR COMPOUND G-5555 | TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1z3z:A (GLY352) to (ALA408) THE CRYSTAL STRUCTURE OF A DGD MUTANT: Q52A | DGD MUTANT, LYASE
3lj2:A (GLY686) to (ALA744) IRE1 COMPLEXED WITH JAK INHIBITOR I | KINASE, KINASE INHIBITOR, NUCLEASE ACTIVATOR, ATP-BINDING, ENDOPLASMIC RETICULUM, GLYCOPROTEIN, HYDROLASE, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UNFOLDED PROTEIN RESPONSE
3lj2:B (GLY686) to (ALA744) IRE1 COMPLEXED WITH JAK INHIBITOR I | KINASE, KINASE INHIBITOR, NUCLEASE ACTIVATOR, ATP-BINDING, ENDOPLASMIC RETICULUM, GLYCOPROTEIN, HYDROLASE, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UNFOLDED PROTEIN RESPONSE
1zj8:A (GLY67) to (TRP137) STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS NIRA PROTEIN | NIRA, SULFITE, NITRITE, REDUCTASE, SIROHEME, FE4-S4, CYS-TYR COVALENT BOND, STRUCTURAL PROTEOMICS IN EUROPE, SPINE, STRUCTURAL GENOMICS, OXIDOREDUCTASE
5dxo:A (PHE129) to (PRO183) STRUCTURE OF ASPERGILLUS FUMIGATUS TREHALOSE-6-PHOSPHATE PHOSPHATASE CRYSTAL FORM 3 | TREHALOSE-6-PHOSPHATE, PHOSPHATASE, HYDROLASE
5dxo:B (PHE129) to (ARG182) STRUCTURE OF ASPERGILLUS FUMIGATUS TREHALOSE-6-PHOSPHATE PHOSPHATASE CRYSTAL FORM 3 | TREHALOSE-6-PHOSPHATE, PHOSPHATASE, HYDROLASE
4asz:A (GLY566) to (GLU634) CRYSTAL STRUCTURE OF APO TRKB KINASE DOMAIN | TRANSFERASE, TRKA, TRKB
1zob:A (GLY352) to (ALA408) CRYSTAL STRUCTURE OF DIALKYLGLYCINE DECARBOXYLASES BOUND WITH CALCIUM ION | DECARBOXYLASE, PYRIDOXAL PHOSPHATE, LYASE
5e7r:A (GLY94) to (PHE176) CRYSTAL STRUCTURE OF TL10-81 BOUND TO TAK1-TAB1 | MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7/TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 1, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4bdi:A (GLY232) to (VAL300) FRAGMENT-BASED SCREENING IDENTIFIES A NEW AREA FOR INHIBITOR BINDING TO CHECKPOINT KINASE 2 (CHK2) | TRANSFERASE
4bdj:A (GLU233) to (VAL300) FRAGMENT-BASED SCREENING IDENTIFIES A NEW AREA FOR INHIBITOR BINDING TO CHECKPOINT KINASE 2 (CHK2) | TRANSFERASE
4qp7:A (GLY37) to (VAL104) CRYSTAL STRUCTURE OF ERK2 IN COMPLEX WITH 2-(1H-PYRAZOL-4-YL)-5H- PYRROLO[2,3-B]PYRAZINE | KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5esp:B (GLU177) to (ASN238) CRYSTAL STRUCTURE OF LAGLIDADG MEGANUCLEASE I-PANMI WITH COORDINATED CALCIUM IONS | HYDROLASE-DNA COMPLEX, LAGLIDADG, HOMING ENDONUCLEASE, MEGANUCLEASE
4bin:A (LYS59) to (GLU116) CRYSTAL STRUCTURE OF THE E. COLI N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMIC | HYDROLASE, BACTERIAL DIVISION
3bp8:D (LEU30) to (ILE70) CRYSTAL STRUCTURE OF MLC/EIIB COMPLEX | ENZYME, IICBGLC, GLUCOSE SIGNALING, MLC, PROTEIN-PROTEIN INTERACTION, TRANSCRIPTION REGULATION, INNER MEMBRANE, KINASE, MEMBRANE, PHOSPHOPROTEIN, PHOSPHOTRANSFERASE SYSTEM, SUGAR TRANSPORT, TRANSFERASE, TRANSMEMBRANE, TRANSPORT
3cag:A (SER107) to (VAL152) CRYSTAL STRUCTURE OF THE OLIGOMERIZATION DOMAIN HEXAMER OF THE ARGININE REPRESSOR PROTEIN FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH 9 ARGININES. | L-ARGININE REPRESSOR, DNA BINDING PROTEIN, OLIGOMERIZATION DOMAIN, CORE, ALPHA/BETA TOPOLOGY, TBSGC, STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, AMINO-ACID BIOSYNTHESIS, ARGININE BIOSYNTHESIS, DNA-BINDING, TRANSCRIPTION, TRANSCRIPTION REGULATION
3cag:B (SER107) to (VAL152) CRYSTAL STRUCTURE OF THE OLIGOMERIZATION DOMAIN HEXAMER OF THE ARGININE REPRESSOR PROTEIN FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH 9 ARGININES. | L-ARGININE REPRESSOR, DNA BINDING PROTEIN, OLIGOMERIZATION DOMAIN, CORE, ALPHA/BETA TOPOLOGY, TBSGC, STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, AMINO-ACID BIOSYNTHESIS, ARGININE BIOSYNTHESIS, DNA-BINDING, TRANSCRIPTION, TRANSCRIPTION REGULATION
3cag:D (SER107) to (VAL152) CRYSTAL STRUCTURE OF THE OLIGOMERIZATION DOMAIN HEXAMER OF THE ARGININE REPRESSOR PROTEIN FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH 9 ARGININES. | L-ARGININE REPRESSOR, DNA BINDING PROTEIN, OLIGOMERIZATION DOMAIN, CORE, ALPHA/BETA TOPOLOGY, TBSGC, STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, AMINO-ACID BIOSYNTHESIS, ARGININE BIOSYNTHESIS, DNA-BINDING, TRANSCRIPTION, TRANSCRIPTION REGULATION
3cag:F (SER107) to (VAL152) CRYSTAL STRUCTURE OF THE OLIGOMERIZATION DOMAIN HEXAMER OF THE ARGININE REPRESSOR PROTEIN FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH 9 ARGININES. | L-ARGININE REPRESSOR, DNA BINDING PROTEIN, OLIGOMERIZATION DOMAIN, CORE, ALPHA/BETA TOPOLOGY, TBSGC, STRUCTURAL GENOMICS, TB STRUCTURAL GENOMICS CONSORTIUM, AMINO-ACID BIOSYNTHESIS, ARGININE BIOSYNTHESIS, DNA-BINDING, TRANSCRIPTION, TRANSCRIPTION REGULATION
4c4i:A (GLN541) to (VAL601) STRUCTURE-BASED DESIGN OF ORALLY BIOAVAILABLE PYRROLOPYRIDINE INHIBITORS OF THE MITOTIC KINASE MPS1 | TRANSFERASE, MITOSIS, STRUCTURE-BASED DRUG DESIGN
3ckw:A (GLY21) to (ILE83) CRYSTAL STRUCTURE OF STERILE 20-LIKE KINASE 3 (MST3, STK24) | STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC, PROTEIN KINASE, MST3, STK24, STERILE 20-LIKE KINASE, ALTERNATIVE SPLICING, ATP-BINDING, CYTOPLASM, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE- PROTEIN KINASE, TRANSFERASE
4ch3:A (LYS321) to (HIS392) STRUCTURE OF PYRROLYSYL-TRNA SYNTHETASE IN COMPLEX WITH ADENYLATED BUTYRYL LYSINE | LIGASE, NON-NATURAL AMINO ACID, PYRROLYSINE
4ch4:A (LYS321) to (MET391) STRUCTURE OF PYRROLYSYL-TRNA SYNTHETASE IN COMPLEX WITH ADENYLATED CROTONYL LYSINE | LIGASE, NON-NATURAL AMINO ACID, PYRROLYSINE
4cs2:A (LYS321) to (HIS392) CATALYTIC DOMAIN OF PYRROLYSYL-TRNA SYNTHETASE MUTANT Y306A, Y384F IN ITS APO FORM | LIGASE
4cs3:A (LYS321) to (HIS392) CATALYTIC DOMAIN OF PYRROLYSYL-TRNA SYNTHETASE MUTANT Y306A, Y384F IN COMPLEX WITH AN ADENYLATED FURAN-BEARING NONCANONICAL AMINO ACID AND PYROPHOSPHATE | LIGASE, AMINOACYL-TRNA SYNTHETASE, PYRROLYSYL-TRNA-SYNTHETASE, NONCANONICAL AMINO ACIDS, FURANS, CROSSLINKING REACTIONS
3oby:A (VAL4) to (GLU66) CRYSTAL STRUCTURE OF ARCHAEOGLOBUS FULGIDUS PELOTA REVEALS INTER- DOMAIN STRUCTURAL PLASTICITY | SM FOLD, HYDROLASE
4tv3:A (LYS776) to (VAL851) ISOLATED P110A SUBUNIT OF PI3KA PROVIDES A PLATFORM FOR STRUCTURE- BASED DRUG DESIGN | LIPID KINASE ACTIVITY, ATPASE ACTIVITY, SURFACE PLASMON RESONANCE (SPR), ISOTHERMAL TITRATION CALORIMETRY (ITC)., TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3owe:F (LYS124) to (ASP194) CRYSTAL STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN G (SEG) IN COMPLEX WITH A HIGH AFFINITY MUTANT MOUSE T-CELL RECEPTOR CHAIN | T-CELL RECEPTOR V BETA DOMAIN, COMPLEX STRUCTURE, IGG DOMAINS, B GRASP, VIRULENCE FACTORS, IMMUNE SYSTEM
3dxp:A (ASN51) to (GLU120) CRYSTAL STRUCTURE OF A PUTATIVE AMINOGLYCOSIDE PHOSPHOTRANSFERASE (REUT_A1007) FROM RALSTONIA EUTROPHA JMP134 AT 2.32 A RESOLUTION | PROTEIN KINASE-LIKE FOLD, STRUCTURAL GENOMICS, JOINT CENTER FOR STRUCTURAL GENOMICS, JCSG, PROTEIN STRUCTURE INITIATIVE, PSI-2, TRANSFERASE
4u8z:A (GLY36) to (ILE98) CRYSTAL STRUCTURE OF MST3 WITH A PYRROLOPYRIMIDINE INHIBITOR (PF- 06447475) | MST3, PYRROLOPYRIMIDINE, INHIBITOR, KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4u9j:A (HIS117) to (ASN180) CRYSTAL STRUCTURE OF AN H-NOX PROTEIN FROM S. ONEIDENSIS IN THE MN(II) LIGATION STATE, Q154A/Q155A/K156A MUTANT | H-NOX. HEMOPROTEIN, GAS SENSOR, SIGNALING PROTEIN
4u9j:B (HIS117) to (ASN180) CRYSTAL STRUCTURE OF AN H-NOX PROTEIN FROM S. ONEIDENSIS IN THE MN(II) LIGATION STATE, Q154A/Q155A/K156A MUTANT | H-NOX. HEMOPROTEIN, GAS SENSOR, SIGNALING PROTEIN
3r2y:A (LEU79) to (GLU139) MK2 KINASE BOUND TO COMPOUND 1 | KINASE DOMAIN, PHOSPHOTRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3r7p:A (GLU184) to (ASN253) THE CRYSTAL STRUCTURE OF I-LTRI | HOMING ENDONUCLEASE, GENE THERAPY, HYDROLASE-DNA COMPLEX
4fti:A (TYR20) to (PHE83) CRYSTAL STRUCTURE OF THE CHK1 | TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4g0a:A (PHE164) to (LYS230) CRYSTALLOGRAPHIC ANALYSIS OF ROTAVIRUS NSP2-RNA COMPLEX REVEALS SPECIFIC RECOGNITION OF 5'-GG SEQUENCE FOR RTPASE ACTIVITY | RNA TRIPHOSPHATASE, RNA BINDING, HYDROLASE ACTIVITY, NUCLEOTIDE BINDING, METAL ION BINDING, HOST CELL CYTOPLASM, HYDROLASE-RNA COMPLEX
4g0j:A (PHE164) to (LYS230) CRYSTALLOGRAPHIC ANALYSIS OF ROTAVIRUS NSP2-RNA COMPLEX REVEALS SPECIFIC RECOGNITION OF 5'-GG SEQUENCE FOR RTPASE ACTIVITY | RNA TRIPHOSPHATASE, RNA BINDING, HYDROLASE ACTIVITY, NUCLEOTIDE BINDING, METAL ION BINDING, HOST CELL CYTOPLASM, HYDROLASE
4g0j:H (PHE164) to (LYS230) CRYSTALLOGRAPHIC ANALYSIS OF ROTAVIRUS NSP2-RNA COMPLEX REVEALS SPECIFIC RECOGNITION OF 5'-GG SEQUENCE FOR RTPASE ACTIVITY | RNA TRIPHOSPHATASE, RNA BINDING, HYDROLASE ACTIVITY, NUCLEOTIDE BINDING, METAL ION BINDING, HOST CELL CYTOPLASM, HYDROLASE
5kqr:A (LYS174) to (VAL222) STRUCTURE OF NS5 METHYLTRANSFERASE FROM ZIKA VIRUS BOUND TO S- ADENOSYLMETHIONINE | ZIKA, FLAVIVIRUS, TRANSFERASE
5tkx:A (GLY41) to (GLU122) CRYSTAL STRUCTURE OF HUMAN VACCINIA-RELATED KINASE 2 (VRK-2) BOUND TO BI-D1870 | TRANSFERASE, PROTEIN KINASE DOMAIN, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX