1nb4:B    (ILE85) to   (THR181)  HC-J4 RNA POLYMERASE APO-FORM  |   HEPATITIS C VIRUS, REPLICATION, RNA POLYMERASE, DE-NOVO PRIMING, CRYSTAL STRUCTURE, FUNCTION ANALYSIS, HCV, NS5B, RDRP, TRANSFERASE 
1nb6:A    (SER84) to   (THR181)  HC-J4 RNA POLYMERASE COMPLEXED WITH UTP  |   HEPATITIS C VIRUS, REPLICATION, RNA POLYMERASE, DE-NOVO PRIMING, CRYSTAL STRUCTURE, FUNCTION ANALYSIS, HCV, NS5B, RDRP, TRANSFERASE 
1nb6:B    (ILE85) to   (THR181)  HC-J4 RNA POLYMERASE COMPLEXED WITH UTP  |   HEPATITIS C VIRUS, REPLICATION, RNA POLYMERASE, DE-NOVO PRIMING, CRYSTAL STRUCTURE, FUNCTION ANALYSIS, HCV, NS5B, RDRP, TRANSFERASE 
1nhu:A    (SER84) to   (THR181)  HEPATITIS C VIRUS RNA POLYMERASE IN COMPLEX WITH NON- NUCLEOSIDE ANALOGUE INHIBITOR  |   HEPATITIS C; RNA POLYMERASE; ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE 
1nhu:B    (SER84) to   (THR181)  HEPATITIS C VIRUS RNA POLYMERASE IN COMPLEX WITH NON- NUCLEOSIDE ANALOGUE INHIBITOR  |   HEPATITIS C; RNA POLYMERASE; ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE 
1nhv:A    (VAL85) to   (GLY188)  HEPATITIS C VIRUS RNA POLYMERASE IN COMPLEX WITH NON- NUCLEOSIDE ANALOGUE INHIBITOR  |   HEPATITIS C; RNA POLYMERASE; ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE 
1nhv:B    (VAL85) to   (GLY188)  HEPATITIS C VIRUS RNA POLYMERASE IN COMPLEX WITH NON- NUCLEOSIDE ANALOGUE INHIBITOR  |   HEPATITIS C; RNA POLYMERASE; ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE 
2awz:A    (SER84) to   (THR181)  HEPATITIS C VIRUS NS5B RNA POLYMERASE IN COMPLEX WITH A COVALENT INHIBITOR (5H)  |   HCV, NS5B, POLYMERASE, FINGERS, THUMB, PALM, TRANSFERASE 
2awz:B    (SER84) to   (THR181)  HEPATITIS C VIRUS NS5B RNA POLYMERASE IN COMPLEX WITH A COVALENT INHIBITOR (5H)  |   HCV, NS5B, POLYMERASE, FINGERS, THUMB, PALM, TRANSFERASE 
2ax0:A    (SER84) to   (THR181)  HEPATITIS C VIRUS NS5B RNA POLYMERASE IN COMPLEX WITH A COVALENT INHIBITOR (5X)  |   HCV, NS5B, POLYMERASE, FINGERS, THUMB, PALM, TRANSFERASE 
2ax0:B    (VAL85) to   (THR181)  HEPATITIS C VIRUS NS5B RNA POLYMERASE IN COMPLEX WITH A COVALENT INHIBITOR (5X)  |   HCV, NS5B, POLYMERASE, FINGERS, THUMB, PALM, TRANSFERASE 
2ax1:A    (SER84) to   (THR181)  HEPATITIS C VIRUS NS5B RNA POLYMERASE IN COMPLEX WITH A COVALENT INHIBITOR (5EE)  |   HCV, NS5B, POLYMERASE, FINGERS, THUMB, PALM, TRANSFERASE 
2ax1:B    (SER84) to   (THR181)  HEPATITIS C VIRUS NS5B RNA POLYMERASE IN COMPLEX WITH A COVALENT INHIBITOR (5EE)  |   HCV, NS5B, POLYMERASE, FINGERS, THUMB, PALM, TRANSFERASE 
4wt9:A    (THR84) to   (LYS181)  APO CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH E86Q E87Q S15G C223H V321I AND DELTA8 MUTATIONS  |   HCV, VIRAL, NS5B, RDRP, RESISTANCE MUTATION, DELTA8 BETA HAIRPIN LOOP DELETION, TRANSFERASE 
1c2p:A    (VAL85) to   (THR181)  HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE  |   POLYMERASE RNA-DEPENDENT RNA POLYMERASE HEPATITIS C VIRUS NS5B APOENZYME, TRANSFERASE 
1c2p:B    (VAL85) to   (THR181)  HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE  |   POLYMERASE RNA-DEPENDENT RNA POLYMERASE HEPATITIS C VIRUS NS5B APOENZYME, TRANSFERASE 
3ska:A    (ILE85) to   (THR181)  I. NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE 2- CARBOXYLIC ACIDS WITH C3-HETEROCYCLES  |   RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3ska:B    (ILE85) to   (THR181)  I. NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE 2- CARBOXYLIC ACIDS WITH C3-HETEROCYCLES  |   RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3ske:A    (ILE85) to   (THR181)  I. NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE 2- CARBOXYLIC ACIDS WITH C3-HETEROCYCLES  |   RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3ske:B    (ILE85) to   (THR181)  I. NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE 2- CARBOXYLIC ACIDS WITH C3-HETEROCYCLES  |   RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3skh:B    (SER84) to   (MET187)  I. NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE 2- CARBOXYLIC ACIDS WITH C3-HETEROCYCLES  |   RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3fqk:A    (VAL85) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B (BK 1-570) WITH HCV-796 INHIBITOR  |   HCV, HEPATITIS, NS5B, TRANSFERASE, RNA-DEPENDENT RNA POLYMERASE, HCV-796 
3fqk:B    (VAL85) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B (BK 1-570) WITH HCV-796 INHIBITOR  |   HCV, HEPATITIS, NS5B, TRANSFERASE, RNA-DEPENDENT RNA POLYMERASE, HCV-796 
3fql:A    (SER84) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B (CON1 1-570) WITH HCV-796 INHIBITOR  |   HCV, HEPATITIS, NS5B, TRANSFERASE, RNA-DEPENDENT RNA POLYMERASE, HCV- 796 
3frz:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE IN COMPLEX WITH PF868554  |   VIRAL POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC 
1csj:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF THE RNA-DEPENDENT RNA POLYMERASE OF HEPATITIS C VIRUS  |   POLYPROTEIN, GLYCOPROTEIN, RNA-DIRECTED RNA POLYMERASE, CORE PROTEIN, COAT PROTEIN, ENVELOPE PROTEIN, HELICASE, ATP-BINDING, TRANSMEMBRANE, NONSTRUCTURAL PROTEIN, TRANSFERASE 
1csj:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF THE RNA-DEPENDENT RNA POLYMERASE OF HEPATITIS C VIRUS  |   POLYPROTEIN, GLYCOPROTEIN, RNA-DIRECTED RNA POLYMERASE, CORE PROTEIN, COAT PROTEIN, ENVELOPE PROTEIN, HELICASE, ATP-BINDING, TRANSMEMBRANE, NONSTRUCTURAL PROTEIN, TRANSFERASE 
4ih5:A    (VAL85) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B (BK) WITH FRAGMENT-BASED COMPOUNDS  |   FRAGMENT BASED DRUG DESIGN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4ih5:B    (VAL85) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B (BK) WITH FRAGMENT-BASED COMPOUNDS  |   FRAGMENT BASED DRUG DESIGN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4ih6:A    (SER84) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B (BK) WITH FRAGMENT-BASED COMPOUNDS  |   FRAGMENT BASED DRUG DESIGN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4ih6:B    (SER84) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B (BK) WITH FRAGMENT-BASED COMPOUNDS  |   FRAGMENT BASED DRUG DESIGN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4ih7:A    (VAL85) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B (BK) WITH FRAGMENT-BASED COMPOUNDS  |   FRAGMENT BASED DRUG DESIGN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4ih7:B    (SER84) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B (BK) WITH FRAGMENT-BASED COMPOUNDS  |   FRAGMENT BASED DRUG DESIGN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
2qe2:A    (VAL85) to   (THR181)  STRUCTURE OF HCV NS5B BOUND TO AN ANTHRANILIC ACID INHIBITOR  |   TRANSFERASE 
2qe2:B    (VAL85) to   (THR181)  STRUCTURE OF HCV NS5B BOUND TO AN ANTHRANILIC ACID INHIBITOR  |   TRANSFERASE 
2qe5:A    (VAL85) to   (THR181)  STRUCTURE OF HCV NS5B BOUND TO AN ANTHRANILIC ACID INHIBITOR  |   TRANSFERASE POLYMERASE 
2qe5:B    (SER84) to   (THR181)  STRUCTURE OF HCV NS5B BOUND TO AN ANTHRANILIC ACID INHIBITOR  |   TRANSFERASE POLYMERASE 
2qe5:C    (SER84) to   (THR181)  STRUCTURE OF HCV NS5B BOUND TO AN ANTHRANILIC ACID INHIBITOR  |   TRANSFERASE POLYMERASE 
2qe5:D    (SER84) to   (THR181)  STRUCTURE OF HCV NS5B BOUND TO AN ANTHRANILIC ACID INHIBITOR  |   TRANSFERASE POLYMERASE 
3g86:A    (SER84) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B (BK 1-570) WITH THIAZINE INHIBITOR  |   HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3- BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC 
3g86:B    (SER84) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B (BK 1-570) WITH THIAZINE INHIBITOR  |   HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3- BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC 
4iz0:A    (ILE85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2,4,5- TRICHLORO-N-(5-METHYL-1,2-OXAZOL-3-YL)BENZENESULFONAMIDE  |   HCV NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4iz0:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2,4,5- TRICHLORO-N-(5-METHYL-1,2-OXAZOL-3-YL)BENZENESULFONAMIDE  |   HCV NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4j02:A    (ILE85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH [(1R)-5,8- DICHLORO-1-PROPYL-1,3,4,9-TETRAHYDROPYRANO[3,4-B]INDOL-1-YL]ACETIC ACID  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4j02:B    (ILE85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH [(1R)-5,8- DICHLORO-1-PROPYL-1,3,4,9-TETRAHYDROPYRANO[3,4-B]INDOL-1-YL]ACETIC ACID  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4j04:A    (ILE85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 4-CHLORO-2- {[(2,4,5-TRICHLOROPHENYL)SULFONYL]AMINO}BENZOIC ACID  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4j04:B    (ILE85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 4-CHLORO-2- {[(2,4,5-TRICHLOROPHENYL)SULFONYL]AMINO}BENZOIC ACID  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4j06:A    (ILE85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2-{[(5- BROMOTHIOPHEN-2-YL)SULFONYL]AMINO}-4-CHLOROBENZOIC ACID  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4j06:B    (ILE85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2-{[(5- BROMOTHIOPHEN-2-YL)SULFONYL]AMINO}-4-CHLOROBENZOIC ACID  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4j08:A    (ILE85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2-{[(4- METHYLPHENYL)SULFONYL]AMINO}-5-PHENOXYBENZOIC ACID  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4j08:B    (ILE85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2-{[(4- METHYLPHENYL)SULFONYL]AMINO}-5-PHENOXYBENZOIC ACID  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4j0a:A    (ILE85) to   (SER210)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2-{[(4- METHYLPHENYL)SULFONYL]AMINO}-4-PHENOXYBENZOIC ACID  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4j0a:B    (ILE85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH 2-{[(4- METHYLPHENYL)SULFONYL]AMINO}-4-PHENOXYBENZOIC ACID  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3gnv:A    (SER84) to   (THR181)  HCV NS5B POLYMERASE IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR 1B  |   HEPATITIS C VIRUS, 1.5-BENZODIAZEPINE, NS5B, SULFONE, POLYMERASE, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION 
3gnv:B    (ILE85) to   (VAL186)  HCV NS5B POLYMERASE IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR 1B  |   HEPATITIS C VIRUS, 1.5-BENZODIAZEPINE, NS5B, SULFONE, POLYMERASE, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION 
2d3u:A    (SER84) to   (THR181)  X-RAY CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA DEPENDENT RNA POLYMERASE IN COMPLEX WITH NON-NUCLEOSIDE ANALOGUE INHIBITOR  |   HEPATITIS C VIRUS, RNA-DEPENDENT RNA POLYMERASE, ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE 
2d3u:B    (SER84) to   (THR181)  X-RAY CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA DEPENDENT RNA POLYMERASE IN COMPLEX WITH NON-NUCLEOSIDE ANALOGUE INHIBITOR  |   HEPATITIS C VIRUS, RNA-DEPENDENT RNA POLYMERASE, ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE 
3gnw:A    (SER84) to   (THR181)  HCV NS5B POLYMERASE IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR 4C  |   1,5-BENZODIAZEPINES, HEPATITIS C VIRUS, NS5B, POLYMERASE, SULFONE, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION 
3gnw:B    (ILE85) to   (THR181)  HCV NS5B POLYMERASE IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR 4C  |   1,5-BENZODIAZEPINES, HEPATITIS C VIRUS, NS5B, POLYMERASE, SULFONE, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION 
2d3z:A    (SER84) to   (THR181)  X-RAY CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH NON-NUCLEOSIDE ANALOGUE INHIBITOR  |   HEPATITIS C VIRUS, RNA POLYMERASE, ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE 
2d3z:B    (VAL85) to   (THR181)  X-RAY CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH NON-NUCLEOSIDE ANALOGUE INHIBITOR  |   HEPATITIS C VIRUS, RNA POLYMERASE, ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE 
3gsz:A    (VAL85) to   (LYS181)  STRUCTURE OF THE GENOTYPE 2B HCV POLYMERASE  |   POLYMERASE, HCV, TRANSFERASE 
3gsz:B    (VAL85) to   (LYS181)  STRUCTURE OF THE GENOTYPE 2B HCV POLYMERASE  |   POLYMERASE, HCV, TRANSFERASE 
3gyn:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL MONOCYCLIC DIHYDROPYRIDINONE INHIBITOR  |   PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, TRANSCRIPTION, TRANSFERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION REGULATION, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC 
3gyn:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL MONOCYCLIC DIHYDROPYRIDINONE INHIBITOR  |   PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, TRANSCRIPTION, TRANSFERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION REGULATION, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC 
4jjs:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 2  |   LAVAL, HCV VIRUS RDRP NS5B POLYMERASE, TRANSFERASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX 
4jjs:B    (ILE85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 2  |   LAVAL, HCV VIRUS RDRP NS5B POLYMERASE, TRANSFERASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX 
4jju:A    (ILE85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 29  |   VIRUS RDRP NS5B POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4jju:B    (ILE85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 29  |   VIRUS RDRP NS5B POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3h2l:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH A NOVEL BICYCLIC DIHYDRO-PYRIDINONE INHIBITOR  |   PROTEIN-LIGAND COMPLEX, HEPATITIS C, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, ACETYLATION, APOPTOSIS, ATP-BINDING 
3h2l:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH A NOVEL BICYCLIC DIHYDRO-PYRIDINONE INHIBITOR  |   PROTEIN-LIGAND COMPLEX, HEPATITIS C, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, ACETYLATION, APOPTOSIS, ATP-BINDING 
3h59:A    (SER84) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B WITH THIAZINE INHIBITOR 2  |   HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC 
3h59:B    (SER84) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B WITH THIAZINE INHIBITOR 2  |   HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC 
3tyv:A    (ILE85) to   (THR181)  SAR DEVELOPMENT AND DISCOVERY OF POTENT INDOLE-BASED INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE  |   RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3tyv:B    (ILE85) to   (THR181)  SAR DEVELOPMENT AND DISCOVERY OF POTENT INDOLE-BASED INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE  |   RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
1quv:A    (VAL85) to   (THR181)  CRYSTAL STRUCTURE OF THE RNA DIRECTED RNA POLYMERASE OF HEPATITIS C VIRUS  |   RNA DEPENDENT RNA POLYMERASE, REPLICASE, HCV, NS5B, TRANSFERASE 
3h98:A    (VAL85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B 1B WITH (1,1-DIOXO-2H-[1,2, 4]BENZOTHIADIAZIN-3-YL) AZOLO[1,5-A]PYRIMIDINE DERIVATIVE  |   RNA POLYMERASE, NUCLEOTIDE BINDING, TRANSFERASE 
3h98:B    (VAL85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B 1B WITH (1,1-DIOXO-2H-[1,2, 4]BENZOTHIADIAZIN-3-YL) AZOLO[1,5-A]PYRIMIDINE DERIVATIVE  |   RNA POLYMERASE, NUCLEOTIDE BINDING, TRANSFERASE 
4jtw:A    (ILE85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COUPOUND 1  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4jtw:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COUPOUND 1  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4jtz:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 4  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4jtz:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 4  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4jty:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH COMPOUND 2  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4jty:B    (ILE85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH COMPOUND 2  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4ju1:A    (ILE85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 6  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4ju1:B    (ILE85) to   (VAL186)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 6  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4ju3:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 8  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4ju3:B    (ILE85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 8  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4ju4:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 22  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4ju4:B    (ILE85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 22  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4ju6:A    (ILE85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 24  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4ju6:B    (ILE85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 24  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4ju7:A    (ILE85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 24  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4ju7:B    (ILE85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 24  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3u4r:A    (SER84) to   (THR181)  NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE C2 ACYL SULFONAMIDES  |   NUCLEOTIDYL TRANSFER, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3u4r:B    (SER84) to   (THR181)  NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE C2 ACYL SULFONAMIDES  |   NUCLEOTIDYL TRANSFER, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4jvq:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 9  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4jvq:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 9  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
4jy1:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 5  |   TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4jy1:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 5  |   TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3hhk:A    (SER84) to   (THR181)  HCV NS5B POLYMERASE COMPLEX WITH A SUBSTITUTED BENZOTHIADIZINE  |   NS5B, POLYMERASE, HCV, INHHIBITOR, ATP-BINDING, ENVELOPE PROTEIN, HELICASE, HYDROLASE, MEMBRANE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3hhk:B    (SER84) to   (THR181)  HCV NS5B POLYMERASE COMPLEX WITH A SUBSTITUTED BENZOTHIADIZINE  |   NS5B, POLYMERASE, HCV, INHHIBITOR, ATP-BINDING, ENVELOPE PROTEIN, HELICASE, HYDROLASE, MEMBRANE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3udl:A    (VAL85) to   (THR181)  3-HETEROCYCLYL QUINOLONE BOUND TO HCV NS5B  |   HCV, POLYMERASE, DRUG DESIGN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3udl:B    (SER84) to   (THR181)  3-HETEROCYCLYL QUINOLONE BOUND TO HCV NS5B  |   HCV, POLYMERASE, DRUG DESIGN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3udl:C    (SER84) to   (THR181)  3-HETEROCYCLYL QUINOLONE BOUND TO HCV NS5B  |   HCV, POLYMERASE, DRUG DESIGN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3udl:D    (SER84) to   (THR181)  3-HETEROCYCLYL QUINOLONE BOUND TO HCV NS5B  |   HCV, POLYMERASE, DRUG DESIGN, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3hkw:A    (SER84) to   (LYS181)  HCV NS5B GENOTYPE 1A IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR 6  |   HCV POLYMERASE, SUBTYPE 1A, 1,5-BENZODIAZEPINE, TRANSFERASE 
3hkw:B    (SER84) to   (LYS181)  HCV NS5B GENOTYPE 1A IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR 6  |   HCV POLYMERASE, SUBTYPE 1A, 1,5-BENZODIAZEPINE, TRANSFERASE 
3hkw:C    (SER84) to   (LYS181)  HCV NS5B GENOTYPE 1A IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR 6  |   HCV POLYMERASE, SUBTYPE 1A, 1,5-BENZODIAZEPINE, TRANSFERASE 
3hky:A    (ILE85) to   (THR181)  HCV NS5B POLYMERASE GENOTYPE 1B IN COMPLEX WITH 1,5 BENZODIAZEPINE 6  |   HEPATITIS C VIRUS, 1,5-BENZODIAZEPINE, GENOTYPE, NS5B, POLYMERASE, BIACORE, REPLICON, TRANSFERASE 
3hky:B    (ILE85) to   (THR181)  HCV NS5B POLYMERASE GENOTYPE 1B IN COMPLEX WITH 1,5 BENZODIAZEPINE 6  |   HEPATITIS C VIRUS, 1,5-BENZODIAZEPINE, GENOTYPE, NS5B, POLYMERASE, BIACORE, REPLICON, TRANSFERASE 
4kai:A    (SER84) to   (THR181)  HCV NS5B GT1B N316 WITH GSK5852A  |   HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, RNA DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX, REPLICATION- REPLICATION INHIBITOR COMPLEX 
4kai:B    (VAL85) to   (THR181)  HCV NS5B GT1B N316 WITH GSK5852A  |   HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, RNA DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX, REPLICATION- REPLICATION INHIBITOR COMPLEX 
4kb7:A    (SER84) to   (THR181)  HCV NS5B GT1B N316Y WITH CMPD 32  |   HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DIRECTED RNA POLYMERASE, TAR7360, RNA-DEPENDENT RNA POLYMERASE, REPLICATION-REPLICATION INHIBITOR COMPLEX 
4kb7:B    (SER84) to   (THR181)  HCV NS5B GT1B N316Y WITH CMPD 32  |   HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DIRECTED RNA POLYMERASE, TAR7360, RNA-DEPENDENT RNA POLYMERASE, REPLICATION-REPLICATION INHIBITOR COMPLEX 
4kbi:A    (SER84) to   (THR181)  HCV NS5B GT1B N316Y WITH CMPD 4  |   HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DIRECTED RNA POLYMERASE, TAR7360, POLYMERASE, RNA DEPENDENT RNA POLYMERASE, REPLICATION-REPLICATION INHIBITOR COMPLEX 
4kbi:B    (SER84) to   (THR181)  HCV NS5B GT1B N316Y WITH CMPD 4  |   HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DIRECTED RNA POLYMERASE, TAR7360, POLYMERASE, RNA DEPENDENT RNA POLYMERASE, REPLICATION-REPLICATION INHIBITOR COMPLEX 
4ke5:A    (SER84) to   (THR181)  HCV NS5B GT1B N316Y WITH GSK5852  |   HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DIRECTED RNA POLYMERASE, POLYMERASE, RNA REPLICATION, REPLICATION- REPLICATION INHIBITOR COMPLEX 
4ke5:B    (SER84) to   (THR181)  HCV NS5B GT1B N316Y WITH GSK5852  |   HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DIRECTED RNA POLYMERASE, POLYMERASE, RNA REPLICATION, REPLICATION- REPLICATION INHIBITOR COMPLEX 
4khm:A    (SER84) to   (LYS181)  HCV NS5B GT1A WITH GSK5852  |   HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DEPENDENT RNA POLYMERASE, RNA DIRECTED RNA POLYMERASE, REPLICATION- REPLICATION INHIBITOR COMPLEX 
4khm:B    (SER84) to   (LYS181)  HCV NS5B GT1A WITH GSK5852  |   HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DEPENDENT RNA POLYMERASE, RNA DIRECTED RNA POLYMERASE, REPLICATION- REPLICATION INHIBITOR COMPLEX 
3uph:A    (ILE85) to   (THR181)  SYNTHESIS OF NOVEL 4,5-DIHYDROFURANO INDOLES AND THEIR EVALUATION AS HCV NS5B POLYMERASE INHIBITORS  |   TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3uph:B    (SER84) to   (THR181)  SYNTHESIS OF NOVEL 4,5-DIHYDROFURANO INDOLES AND THEIR EVALUATION AS HCV NS5B POLYMERASE INHIBITORS  |   TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3upi:A    (SER84) to   (THR181)  SYNTHESIS OF NOVEL 4,5-DIHYDROFURANO INDOLES AND THEIR EVALUATION AS HCV NS5B POLYMERASE INHIBITORS  |   TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3upi:B    (SER84) to   (THR181)  SYNTHESIS OF NOVEL 4,5-DIHYDROFURANO INDOLES AND THEIR EVALUATION AS HCV NS5B POLYMERASE INHIBITORS  |   TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
2fvc:A    (VAL85) to   (THR181)  CRYSTAL STRUCTURE OF NS5B BK STRAIN (DELTA 24) IN COMPLEX WITH A 3-(1, 1-DIOXO-2H-(1,2,4)-BENZOTHIADIAZIN-3-YL)-4-HYDROXY-2(1H)-QUINOLINONE  |   HCV POLYMERASE, THIADIAZIN INHIBITOR, TRANSFERASE 
2fvc:B    (VAL85) to   (THR181)  CRYSTAL STRUCTURE OF NS5B BK STRAIN (DELTA 24) IN COMPLEX WITH A 3-(1, 1-DIOXO-2H-(1,2,4)-BENZOTHIADIAZIN-3-YL)-4-HYDROXY-2(1H)-QUINOLINONE  |   HCV POLYMERASE, THIADIAZIN INHIBITOR, TRANSFERASE 
1gx5:A    (SER84) to   (THR181)  HEPATITIS C VIRUS RNA POLYMERASE IN COMPLEX WITH GTP AND MANGANESE  |   TRANSFERASE, POLYPROTEIN, GLYCOPROTEIN, RNA-DIRECTED RNA POLYMERASE, CORE PROTEIN, COAT PROTEIN, ENVELOPE PROTEIN, HELICASE, ATP BINDING, TRANSMEMBRANE, NONSTRUCTURAL PROTEIN 
1gx6:A    (SER84) to   (THR181)  HEPATITIS C VIRUS RNA POLYMERASE IN COMPLEX WITH UTP AND MANGANESE  |   POLYMERASE, RNA-DEPENDENT RNA POLYMERASE, VIRUS REPLICATION, INITIATION, POLYPROTEIN, GLYCOPROTEIN, TRANSFERASE, RNA-DIRECTED RNA POLYMERASE 
2gc8:A    (VAL85) to   (THR181)  STRUCTURE OF A PROLINE SULFONAMIDE INHIBITOR BOUND TO HCV NS5B POLYMERASE  |   TRANSFERASE 
2gc8:B    (VAL85) to   (THR181)  STRUCTURE OF A PROLINE SULFONAMIDE INHIBITOR BOUND TO HCV NS5B POLYMERASE  |   TRANSFERASE 
2giq:A    (SER84) to   (THR181)  HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B WITH NNI-2 INHIBITOR  |   HCV, HEPATITIS, NS5B, TRANSFERASE, RNA-DEPENDENT RNA POLYMERASE 
2giq:B    (SER84) to   (THR181)  HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B WITH NNI-2 INHIBITOR  |   HCV, HEPATITIS, NS5B, TRANSFERASE, RNA-DEPENDENT RNA POLYMERASE 
2gir:A    (VAL85) to   (THR181)  HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B WITH NNI-1 INHIBITOR  |   HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE 
2gir:B    (VAL85) to   (THR181)  HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B WITH NNI-1 INHIBITOR  |   HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE 
3igv:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL MONOCYCLIC DIHYDRO-PYRIDINONE INHIBITOR  |   PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, HYDROLASE, ANTIVIRAL, METAL BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, ATP-BINDING, DISULFIDE BOND, HOST-VIRUS INTERACTION, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEUS, TRANSCRIPTION, TRANSCRIPTION REGULATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC 
3igv:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL MONOCYCLIC DIHYDRO-PYRIDINONE INHIBITOR  |   PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, HYDROLASE, ANTIVIRAL, METAL BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, TRANSFERASE, ATP-BINDING, DISULFIDE BOND, HOST-VIRUS INTERACTION, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEUS, TRANSCRIPTION, TRANSCRIPTION REGULATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC 
2hai:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE IN COMPLEX WITH NOVEL CLASS OF DIHYDROPYRONE-CONTAINING INHIBITOR.  |   HCV RNA POLYMERASE, TRANSFERASE 
2wcx:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN COMPLEX WITH THIENOPYRROLE-BASED FINGER-LOOP INHIBITORS  |   ENVELOPE PROTEIN, HEPATITIS C VIRUS, RNA-DEPENDENT RNA-POLYMERASE, NUCLEOTIDE-BINDING, ALLOSTERIC INHIBITOR, NON NUCLEOSIDE INHIBITOR, NNI, HCV, NS5B, MEMBRANE, HELICASE, HYDROLASE, POLYMERASE, ATP-BINDING, RNA-BINDING, GENOTYPE 1B, VIRAL PROTEIN, TRANSMEMBRANE, RNA REPLICATION 
3vqs:A    (VAL85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE WITH A NOVEL PIPERAZINE INHIBITOR  |   RNA-DEPENDENT RNA POLYMERASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3vqs:B    (VAL85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE WITH A NOVEL PIPERAZINE INHIBITOR  |   RNA-DEPENDENT RNA POLYMERASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3vqs:C    (VAL85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE WITH A NOVEL PIPERAZINE INHIBITOR  |   RNA-DEPENDENT RNA POLYMERASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
3vqs:D    (VAL85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE WITH A NOVEL PIPERAZINE INHIBITOR  |   RNA-DEPENDENT RNA POLYMERASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX 
2hwh:A    (SER84) to   (THR181)  HCV NS5B ALLOSTERIC INHIBITOR COMPLEX  |   HCV, NS5B, VIRAL RNA-DIRECTED RNA POLYMERASE, RDRP, ALLOSTERIC INHIBITOR, HCV INHIBITOR COMPLEX, TRANSFERASE 
2hwh:B    (SER84) to   (THR181)  HCV NS5B ALLOSTERIC INHIBITOR COMPLEX  |   HCV, NS5B, VIRAL RNA-DIRECTED RNA POLYMERASE, RDRP, ALLOSTERIC INHIBITOR, HCV INHIBITOR COMPLEX, TRANSFERASE 
2hwi:A    (VAL85) to   (THR181)  HCV NS5B ALLOSTERIC INHIBITOR COMPLEX  |   HCV, NS5B, VIRAL RNA-DIRECTED RNA POLYMERASE, RDRP, ALLOSTERIC INHIBITOR, HCV INHIBITOR COMPLEX, TRANSFERASE 
2hwi:B    (VAL85) to   (THR181)  HCV NS5B ALLOSTERIC INHIBITOR COMPLEX  |   HCV, NS5B, VIRAL RNA-DIRECTED RNA POLYMERASE, RDRP, ALLOSTERIC INHIBITOR, HCV INHIBITOR COMPLEX, TRANSFERASE 
2wrm:A    (SER84) to   (GLY188)  IDENTIFICATION OF NOVEL ALLOSTERIC INHIBITORS OF HEPATITIS C VIRUS NS5B POLYMERASE THUMB DOMAIN (SITE II) BY STRUCTURE-BASED DESIGN  |   TRANSFERASE, NON-NUCLEOSIDE INHIBITOR, NNI, VIRAL PROTEIN 
2i1r:A    (SER84) to   (THR181)  NOVEL THIAZOLONES AS HCV NS5B POLYMERASE INHIBITORS: FURTHER DESIGNS, SYNTHESIS, SAR AND X-RAY COMPLEX STRUCTURE  |   HCV, NS5B, VIRAL RNA-DIRECTED RNA POLYMERASE, RDRP, ALLOSTERIC INHIBITOR, HCV INHIBITOR COMPLEX, TRANSFERASE 
2i1r:B    (SER84) to   (THR181)  NOVEL THIAZOLONES AS HCV NS5B POLYMERASE INHIBITORS: FURTHER DESIGNS, SYNTHESIS, SAR AND X-RAY COMPLEX STRUCTURE  |   HCV, NS5B, VIRAL RNA-DIRECTED RNA POLYMERASE, RDRP, ALLOSTERIC INHIBITOR, HCV INHIBITOR COMPLEX, TRANSFERASE 
2ijn:A    (VAL85) to   (THR181)  ISOTHIAZOLES AS ACTIVE-SITE INHIBITORS OF HCV NS5B POLYMERASE  |   HCV; NS5B; VIRAL RNA DIRECTED RNA POLYMERASE; RDRP; ACTIVE SITE; COVALENT INHIBITOR, TRANSCRIPTION,TRANSFERASE 
2ijn:B    (SER84) to   (THR181)  ISOTHIAZOLES AS ACTIVE-SITE INHIBITORS OF HCV NS5B POLYMERASE  |   HCV; NS5B; VIRAL RNA DIRECTED RNA POLYMERASE; RDRP; ACTIVE SITE; COVALENT INHIBITOR, TRANSCRIPTION,TRANSFERASE 
4mia:A    (SER84) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH RG7109 (N-{4-[6-TERT-BUTYL-5-METHOXY-8-(6-METHOXY-2-OXO-2,5- DIHYDROPYRIDIN-3-YL)QUINOLIN-3-YL]PHENYL}METHANESULFONAMIDE)  |   POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4mia:B    (SER84) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH RG7109 (N-{4-[6-TERT-BUTYL-5-METHOXY-8-(6-METHOXY-2-OXO-2,5- DIHYDROPYRIDIN-3-YL)QUINOLIN-3-YL]PHENYL}METHANESULFONAMIDE)  |   POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4mib:A    (VAL85) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH COMPOUND 48 (N-({(3S)-1-[6-TERT-BUTYL-5-METHOXY-8-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)QUINOLIN-3-YL]PYRROLIDIN-3-YL}METHYL) METHANESULFONAMIDE)  |   POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4mib:B    (VAL85) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH COMPOUND 48 (N-({(3S)-1-[6-TERT-BUTYL-5-METHOXY-8-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)QUINOLIN-3-YL]PYRROLIDIN-3-YL}METHYL) METHANESULFONAMIDE)  |   POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4mk7:A    (SER84) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 2 (3-(3-TERT-BUTYL-4-METHOXYPHENYL)PYRIDIN-2(1H)-ONE)  |   POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4mk7:B    (SER84) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 2 (3-(3-TERT-BUTYL-4-METHOXYPHENYL)PYRIDIN-2(1H)-ONE)  |   POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4mk8:A    (VAL85) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 4 (N-(4-{2-[3-TERT-BUTYL-2-METHOXY-5-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)PHENYL]ETHYL}PHENYL)METHANESULFONAMIDE)  |   POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4mk8:B    (SER84) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 4 (N-(4-{2-[3-TERT-BUTYL-2-METHOXY-5-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)PHENYL]ETHYL}PHENYL)METHANESULFONAMIDE)  |   POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4mk9:A    (VAL85) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 12 (N-{2-[3-TERT-BUTYL-2-METHOXY-5-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)PHENYL]-1,3-BENZOXAZOL-5-YL}METHANESULFONAMIDE)  |   POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4mk9:B    (VAL85) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 12 (N-{2-[3-TERT-BUTYL-2-METHOXY-5-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)PHENYL]-1,3-BENZOXAZOL-5-YL}METHANESULFONAMIDE)  |   POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4mka:A    (SER84) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 13 (N-{2-[3-TERT-BUTYL-2-METHOXY-5-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)PHENYL]-1,3-BENZOXAZOL-5-YL}METHANESULFONAMIDE)  |   POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4mka:B    (SER84) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 13 (N-{2-[3-TERT-BUTYL-2-METHOXY-5-(2-OXO-1,2- DIHYDROPYRIDIN-3-YL)PHENYL]-1,3-BENZOXAZOL-5-YL}METHANESULFONAMIDE)  |   POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4mkb:A    (VAL85) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 14 (N-(4-{(E)-2-[3-TERT-BUTYL-2-METHOXY-5-(3-OXO-2,3- DIHYDROPYRIDAZIN-4-YL)PHENYL]ETHENYL}PHENYL)METHANESULFONAMIDE)  |   POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4mkb:B    (SER84) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B GENOTYPE 1B (BK) IN COMPLEX WITH INHIBITOR 14 (N-(4-{(E)-2-[3-TERT-BUTYL-2-METHOXY-5-(3-OXO-2,3- DIHYDROPYRIDAZIN-4-YL)PHENYL]ETHENYL}PHENYL)METHANESULFONAMIDE)  |   POLYMERASE, TRANSFERASE, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
2xhu:B    (ILE85) to   (THR181)  HCV-J4 NS5B POLYMERASE ORTHORHOMBIC CRYSTAL FORM  |   REPLICATION, TRANSCRIPTION, TRANSFERASE 
2xhw:A    (ILE85) to   (THR181)  HCV-J4 NS5B POLYMERASE TRIGONAL CRYSTAL FORM  |   REPLICATION, TRANSCRIPTION, TRANSFERASE 
2xi2:A    (SER84) to   (LYS181)  HCV-H77 NS5B APO POLYMERASE  |   TRANSFERASE, NONSTRUCTURAL PROTEIN, REPLICATION, RDRP, DE NOVO PRIMING 
2xi2:B    (SER84) to   (LYS181)  HCV-H77 NS5B APO POLYMERASE  |   TRANSFERASE, NONSTRUCTURAL PROTEIN, REPLICATION, RDRP, DE NOVO PRIMING 
2xi2:C    (SER84) to   (LYS181)  HCV-H77 NS5B APO POLYMERASE  |   TRANSFERASE, NONSTRUCTURAL PROTEIN, REPLICATION, RDRP, DE NOVO PRIMING 
2xi3:A    (SER84) to   (LYS181)  HCV-H77 NS5B POLYMERASE COMPLEXED WITH GTP  |   TRANSFERASE, NONSTRUCTURAL PROTEIN, REPLICATION, RDRP, DE NOVO PRIMING, HEPACIVIRUS 
2xi3:B    (SER84) to   (LYS181)  HCV-H77 NS5B POLYMERASE COMPLEXED WITH GTP  |   TRANSFERASE, NONSTRUCTURAL PROTEIN, REPLICATION, RDRP, DE NOVO PRIMING, HEPACIVIRUS 
2jc0:A    (VAL85) to   (THR181)  CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH INHIBITOR SB655264  |   HEPATITIS, POLYMERASE, HYDROLASE 
2jc0:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH INHIBITOR SB655264  |   HEPATITIS, POLYMERASE, HYDROLASE 
2jc1:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH INHIBITOR SB698223  |   HEPATITIS, POLYMERASE, HYDROLASE 
2jc1:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH INHIBITOR SB698223  |   HEPATITIS, POLYMERASE, HYDROLASE 
2xwh:A    (THR84) to   (LYS181)  HCV-J6 NS5B POLYMERASE STRUCTURE AT 1.8 ANGSTROM  |   TRANSFERASE, REPLICATION 
2xxd:A    (LEU85) to   (LYS181)  HCV-JFH1 NS5B POLYMERASE STRUCTURE AT 1.9 ANGSTROM  |   TRANSFERASE, HEPACIVIRUS, NONSTRUCTURAL PROTEINS, REPLICATION, DE NOVO INITIATION, PRIMING 
2xym:A    (LEU85) to   (LYS181)  HCV-JFH1 NS5B T385A MUTANT  |   TRANSFERASE, HEPACIVIRUS, NONSTRUCTURAL PROTEINS, REPLICATION, DE NOVO INITIATION, PRIMING 
2yoj:A    (ILE85) to   (THR181)  HCV NS5B POLYMERASE COMPLEXED WITH PYRIDONYLINDOLE COMPOUND  |   TRANSFERASE, INHIBITOR 
2yoj:B    (SER84) to   (THR181)  HCV NS5B POLYMERASE COMPLEXED WITH PYRIDONYLINDOLE COMPOUND  |   TRANSFERASE, INHIBITOR 
4obc:A    (THR84) to   (LYS181)  CRYSTAL STRUCTURE OF HCV POLYMERASE NS5B GENOTYPE 2A JFH-1 ISOLATE WITH THE S15G, C223H, V321I RESISTANCE MUTATIONS AGAINST THE GUANOSINE ANALOG GS-0938 (PSI-3529238)  |   HEPATITIS, HCV, VIRAL POLYMERASE, RNA-DEPENDENT-RNA-POLYMERASE, RDRP, RESISTANCE, NUCLEOTIDE ANALOG INHIBITOR, VIRAL PROTEIN, TRANSFERASE 
2o5d:A    (SER84) to   (THR181)  THIAZOLONE-ACYLSULFONAMIDES AS NOVEL HCV NS5B POLYMERASE ALLOSTERIC INHIBITORS: CONVERGENCE OF STRUCTURE-BASED DRUG DESIGN AND X-RAY CRYSTALLOGRAPHIC STUDY  |   HCV, NS5B, VIRAL RNA-DIRECTED RNA POLYMERASE, RDRP, ALLOSTERIC INHIBITOR, HCV INHIBITOR COMPLEX, STRUCTURE- BASED DRUG DESIGN, VIRAL PROTEIN 
2o5d:B    (SER84) to   (THR181)  THIAZOLONE-ACYLSULFONAMIDES AS NOVEL HCV NS5B POLYMERASE ALLOSTERIC INHIBITORS: CONVERGENCE OF STRUCTURE-BASED DRUG DESIGN AND X-RAY CRYSTALLOGRAPHIC STUDY  |   HCV, NS5B, VIRAL RNA-DIRECTED RNA POLYMERASE, RDRP, ALLOSTERIC INHIBITOR, HCV INHIBITOR COMPLEX, STRUCTURE- BASED DRUG DESIGN, VIRAL PROTEIN 
2zku:A    (VAL85) to   (THR181)  STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN A NEW CRYSTAL FORM  |   HEPATITIS C VIRUS, OLIGOMERISATION, ALLOSTERIC NUCLEOTIDE BINDING SITE, TRANSFERASE, ENVELOPE PROTEIN, HELICASE, HYDROLASE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE 
2zku:B    (VAL85) to   (THR181)  STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN A NEW CRYSTAL FORM  |   HEPATITIS C VIRUS, OLIGOMERISATION, ALLOSTERIC NUCLEOTIDE BINDING SITE, TRANSFERASE, ENVELOPE PROTEIN, HELICASE, HYDROLASE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE 
2zku:C    (SER84) to   (THR181)  STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN A NEW CRYSTAL FORM  |   HEPATITIS C VIRUS, OLIGOMERISATION, ALLOSTERIC NUCLEOTIDE BINDING SITE, TRANSFERASE, ENVELOPE PROTEIN, HELICASE, HYDROLASE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE 
2zku:D    (SER84) to   (THR181)  STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE IN A NEW CRYSTAL FORM  |   HEPATITIS C VIRUS, OLIGOMERISATION, ALLOSTERIC NUCLEOTIDE BINDING SITE, TRANSFERASE, ENVELOPE PROTEIN, HELICASE, HYDROLASE, NUCLEOTIDE-BINDING, RNA REPLICATION, TRANSMEMBRANE 
5czb:A    (ILE85) to   (THR181)  HCV NS5B IN COMPLEX WITH LIGAND IDX17119-5  |   HCV POLYMERASE, IDENIX, INHIBITOR, PROTEROS BIOSTRUCTURES GMBH, REPLICATION 
5czb:B    (SER84) to   (THR181)  HCV NS5B IN COMPLEX WITH LIGAND IDX17119-5  |   HCV POLYMERASE, IDENIX, INHIBITOR, PROTEROS BIOSTRUCTURES GMBH, REPLICATION 
4adp:A    (THR84) to   (LYS181)  HCV-J6 NS5B POLYMERASE V405I MUTANT  |   HEPACIVIRUS, NONSTRUCTURAL PROTEINS, REPLICATION, TRANSFERASE, RNA-DIRECTED RNA POLYMERASE, RDRP, DE NOVO INITIATION, PRIMING 
4aex:A    (LEU85) to   (LYS181)  HCV-JFH1 NS5B POLYMERASE STRUCTURE AT 2.4 ANGSTROM IN A PRIMITIVE ORTHORHOMBIC SPACE GROUP  |   TRANSFERASE, HEPACIVIRUS, NONSTRUCTURAL PROTEINS, REPLICATION, DE NOVO INITIATION, PRIMING 
4aex:B    (LEU85) to   (LYS181)  HCV-JFH1 NS5B POLYMERASE STRUCTURE AT 2.4 ANGSTROM IN A PRIMITIVE ORTHORHOMBIC SPACE GROUP  |   TRANSFERASE, HEPACIVIRUS, NONSTRUCTURAL PROTEINS, REPLICATION, DE NOVO INITIATION, PRIMING 
1yuy:A    (THR84) to   (LYS181)  HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE GENOTYPE 2A  |   NS5B POLYMERASE GENOTYPE 2A, VIRAL PROTEIN 
1yv2:A    (THR84) to   (LYS181)  HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE GENOTYPE 2A  |   NS5B POLYMERASE GENOTYPE 2A, TRANSFERASE 
1yvz:A    (THR84) to   (LYS181)  HEPATITIS C VIRUS RNA POLYMERASE GENOTYPE 2A IN COMPLEX WITH NON- NUCLEOSIDE ANALOGUE INHIBITOR  |   NS5B POLYMERASE GENOTYPE 2A, NON-NUCLEOSIDE INHIBITOR, VIRAL PROTEIN 
3lkh:A    (ILE85) to   (THR181)  INHIBITORS OF HEPATITIS C VIRUS POLYMERASE: SYNTHESIS AND CHARACTERIZATION OF NOVEL 6-FLUORO-N-[2-HYDROXY-1(S)-BENZAMIDES  |   HCV, NS5B, POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST CELL MEMBRANE, HOST CYTOPLASM, HOST ENDOPLASMIC RETICULUM, HOST LIPID DROPLET, HOST MEMBRANE, HOST MITOCHONDRION, HOST NUCLEUS, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC 
3lkh:B    (SER84) to   (SER210)  INHIBITORS OF HEPATITIS C VIRUS POLYMERASE: SYNTHESIS AND CHARACTERIZATION OF NOVEL 6-FLUORO-N-[2-HYDROXY-1(S)-BENZAMIDES  |   HCV, NS5B, POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST CELL MEMBRANE, HOST CYTOPLASM, HOST ENDOPLASMIC RETICULUM, HOST LIPID DROPLET, HOST MEMBRANE, HOST MITOCHONDRION, HOST NUCLEUS, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC 
3mf5:A    (VAL85) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B (BK) WITH AMIDE BIOISOSTERE THUMB SITE INHIBITOR  |   HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE 
3mf5:B    (SER84) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B (BK) WITH AMIDE BIOISOSTERE THUMB SITE INHIBITOR  |   HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE 
3br9:A    (VAL85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR  |   PROTEIN-LIGAND COMPLEX, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, CYTOPLASM, HOST- VIRUS INTERACTION, ANTIVIRAL, VIRAL NUCLEOPROTEIN, HYDROLASE 
3br9:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR  |   PROTEIN-LIGAND COMPLEX, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, CYTOPLASM, HOST- VIRUS INTERACTION, ANTIVIRAL, VIRAL NUCLEOPROTEIN, HYDROLASE 
3bsa:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR  |   PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN 
3bsa:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR  |   PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN 
3mwv:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE  |   HCV VIRUS RDRP NS5B POLYMERASE, TRANSFERASE 
3mwv:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE  |   HCV VIRUS RDRP NS5B POLYMERASE, TRANSFERASE 
3mww:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE  |   HCV VIRUS RDRP NS5B POLYMERASE INHIBITOR, TRANSFERASE 
3mww:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE  |   HCV VIRUS RDRP NS5B POLYMERASE INHIBITOR, TRANSFERASE 
3ciz:A    (VAL85) to   (THR181)  CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH SMALL MOLECULE FRAGMENTS  |   DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION 
3ciz:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH SMALL MOLECULE FRAGMENTS  |   DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION 
3cj3:A    (VAL85) to   (THR181)  CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS  |   DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC 
3cj4:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS  |   DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC 
3cj4:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS  |   DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC 
3cj5:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS  |   DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC 
3cso:A    (ILE85) to   (THR181)  HCV POLYMERASE IN COMPLEX WITH A 1,5 BENZODIAZEPINE INHIBITOR  |   1,5-BENZODIAZEPINES, HEPATITIS C VIRUS, NS5B, POLYMERASE, TRANSFERASE 
3cso:B    (ILE85) to   (VAL186)  HCV POLYMERASE IN COMPLEX WITH A 1,5 BENZODIAZEPINE INHIBITOR  |   1,5-BENZODIAZEPINES, HEPATITIS C VIRUS, NS5B, POLYMERASE, TRANSFERASE 
3cwj:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR  |   PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, HEPATITIS, TRANSFERASE, VIRAL PROTEIN 
4ry4:B    (SER84) to   (THR181)  C-TERMINAL MUTANT (Y448F) OF HCV/J4 RNA POLYMERASE  |   HEPATITIS C VIRUS, REPLICATION, FUNCTION ANALYSIS, VIRAL RNA POLYMERASE, RNA RNTP MG, NUCLEOTIDE TRANSFER, TRANSFERASE 
4ry5:A    (SER84) to   (THR181)  C-TERMINAL MUTANT (W550N) OF HCV/J4 RNA POLYMERASE  |   HEPATITIS C VIRUS, REPLICATION, FUNCTION ANALYSIS, VIRAL RNA POLYMERASE, RDRP, RNA RNTP MG, NUCLEOTIDE TRANSFER, TRANSFERASE 
4ry7:A    (SER84) to   (THR181)  C-TERMINAL MUTANT (D559E) OF HCV/J4 RNA POLYMERASE  |   HEPATITIS C VIRUS, REPLICATION, FUNCTION ANALYSIS, VIRAL RNA POLYMERASE, RDRP, RNA RNTP MG, NUCLEOTIDE TRANSFER, TRANSFERASE 
3d28:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL BENZISOTHIAZOLE INHIBITOR  |   PROTEIN-LIGAND COMPLEX, RNA-DIRECTED RNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, NUCLEOTIDE-BINDING, TRANSCRIPTION, HYDROLASE, TRANSFERASE 
3d5m:A    (VAL85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR  |   PROTEIN-LIGAND COMPLEX, RNA POLYMERASE, RNA REPLICATION, RNA-BINDING, TRANSCRIPTION, NUCLEOTIDYLTRANSFERASE, HYDROLASE 
3d5m:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR  |   PROTEIN-LIGAND COMPLEX, RNA POLYMERASE, RNA REPLICATION, RNA-BINDING, TRANSCRIPTION, NUCLEOTIDYLTRANSFERASE, HYDROLASE 
4tlr:A    (VAL85) to   (THR181)  NS5B IN COMPLEX WITH LACTAM-THIOPHENE CARBOXYLIC ACIDS  |   COMPLEX POLYMERASE INHBITOR 
4tn2:A    (SER84) to   (THR181)  NS5B IN COMPLEX WITH LACTAM-THIOPHENE CARBOXYLIC ACIDS  |   COMPLEX POLYMERASE INHBITOR, HYDROLASE 
4txs:A    (SER84) to   (THR181)  AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE  |   INHIBITOR, TETRAMER, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4txs:B    (SER84) to   (THR181)  AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE  |   INHIBITOR, TETRAMER, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4txs:C    (SER84) to   (TYR195)  AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE  |   INHIBITOR, TETRAMER, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4txs:D    (SER84) to   (THR181)  AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE  |   INHIBITOR, TETRAMER, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4ty8:A    (SER84) to   (SER210)  AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE  |   NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4ty8:B    (SER84) to   (GLY188)  AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE  |   NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4ty8:C    (SER84) to   (GLY188)  AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE  |   NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4ty8:D    (SER84) to   (THR181)  AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE  |   NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4ty9:A    (VAL85) to   (THR181)  AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE  |   NS5B, TRANAFERASE-TRANSFERASE INHIBITOR COMPLEX 
4ty9:B    (SER84) to   (THR181)  AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE  |   NS5B, TRANAFERASE-TRANSFERASE INHIBITOR COMPLEX 
4ty9:C    (SER84) to   (THR181)  AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE  |   NS5B, TRANAFERASE-TRANSFERASE INHIBITOR COMPLEX 
4ty9:D    (SER84) to   (GLY188)  AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE  |   NS5B, TRANAFERASE-TRANSFERASE INHIBITOR COMPLEX 
4tya:A    (SER84) to   (THR181)  AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE  |   INHIBITOR, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4tya:B    (SER84) to   (THR181)  AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE  |   INHIBITOR, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4tya:C    (VAL85) to   (GLY188)  AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE  |   INHIBITOR, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4tya:D    (SER84) to   (THR181)  AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE  |   INHIBITOR, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4tyb:A    (SER84) to   (GLY188)  AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE  |   INHIBITOR, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4tyb:B    (SER84) to   (THR181)  AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE  |   INHIBITOR, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4tyb:C    (SER84) to   (THR181)  AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE  |   INHIBITOR, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4tyb:D    (SER84) to   (THR181)  AN LIGAND-OBSERVED MASS SPECTROMETRY-BASED APPROACH INTEGRATED INTO THE FRAGMENT BASED LEAD DISCOVERY PIPELINE  |   INHIBITOR, NS5B, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4dru:A    (SER84) to   (THR181)  HCV NS5B IN COMPLEX WITH MACROCYCLIC INDOLE INHIBITOR  |   HCV POLYMERASE, MACROCYCLE INHIBITOR, THUMB DOMAIN, TRANSFERASE- INHIBITOR COMPLEX 
4dru:B    (SER84) to   (THR181)  HCV NS5B IN COMPLEX WITH MACROCYCLIC INDOLE INHIBITOR  |   HCV POLYMERASE, MACROCYCLE INHIBITOR, THUMB DOMAIN, TRANSFERASE- INHIBITOR COMPLEX 
3e51:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR  |   PROTEIN-LIGAND COMPLEX, RNA-DIRECTED RNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, NUCLEOTIDE-BINDING, TRANSCRIPTION, TRANSFERASE 
3e51:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR  |   PROTEIN-LIGAND COMPLEX, RNA-DIRECTED RNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, NUCLEOTIDE-BINDING, TRANSCRIPTION, TRANSFERASE 
3phe:A    (VAL85) to   (THR181)  HCV NS5B WITH A BOUND QUINOLONE INHIBITOR  |   TRANSFERASE, POLYMERASE, RNA, MITOCHONDRIAL MEMBRANE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX 
3phe:B    (VAL85) to   (THR181)  HCV NS5B WITH A BOUND QUINOLONE INHIBITOR  |   TRANSFERASE, POLYMERASE, RNA, MITOCHONDRIAL MEMBRANE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX 
3phe:C    (SER84) to   (THR181)  HCV NS5B WITH A BOUND QUINOLONE INHIBITOR  |   TRANSFERASE, POLYMERASE, RNA, MITOCHONDRIAL MEMBRANE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX 
3phe:D    (SER84) to   (SER196)  HCV NS5B WITH A BOUND QUINOLONE INHIBITOR  |   TRANSFERASE, POLYMERASE, RNA, MITOCHONDRIAL MEMBRANE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX 
4e76:A    (THR84) to   (LYS181)  APO CRYSTAL STRUCTURE OF HCV NS5B GENOTYPE 2A JFH-1 ISOLATE WITH BETA HAIRPIN LOOP DELETION  |   RDRP, LOOPLESS DELTA8, FLAVIVIRIDAE, HEPATITIS C VIRUS, VIRAL PROTEIN, TRANSFERASE 
4eaw:A    (ILE85) to   (THR181)  HCV NS5B IN COMPLEX WITH IDX375  |   TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4eaw:B    (ILE85) to   (THR181)  HCV NS5B IN COMPLEX WITH IDX375  |   TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3q0z:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID  |   NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3q0z:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID  |   NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4eo6:A    (SER84) to   (THR181)  HCV NS5B POLYMERASE INHIBITORS: TRI-SUBSTITUTED ACYLHYDRAZINES AS TERTIARY AMIDE BIOISOSTERES  |   HCV, NS5B, RNA, RNA POLYMERASE, POLYMERASE INHIBITOR, THUMB SITE 2 INHIBITOR, RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4eo6:B    (VAL85) to   (THR181)  HCV NS5B POLYMERASE INHIBITORS: TRI-SUBSTITUTED ACYLHYDRAZINES AS TERTIARY AMIDE BIOISOSTERES  |   HCV, NS5B, RNA, RNA POLYMERASE, POLYMERASE INHIBITOR, THUMB SITE 2 INHIBITOR, RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3qgd:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND (2R)-4-(2,6-DIMETHOXYPYRIMIDIN-4-YL)-1-[(4-ETHYLPHENYL)SULFONYL]- N-(4-METHOXYBENZYL)PIPERAZINE-2-CARBOXAMIDE  |   NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3qgd:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND (2R)-4-(2,6-DIMETHOXYPYRIMIDIN-4-YL)-1-[(4-ETHYLPHENYL)SULFONYL]- N-(4-METHOXYBENZYL)PIPERAZINE-2-CARBOXAMIDE  |   NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3qge:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND (2R)-4-(2,6-DIMETHOXYPYRIMIDIN-4-YL)-N-(4-METHOXYBENZYL)-1-{[4- (TRIFLUOROMETHOXY)PHENYL]SULFONYL}PIPERAZINE-2-CARBOXAMIDE  |   NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3qge:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND (2R)-4-(2,6-DIMETHOXYPYRIMIDIN-4-YL)-N-(4-METHOXYBENZYL)-1-{[4- (TRIFLUOROMETHOXY)PHENYL]SULFONYL}PIPERAZINE-2-CARBOXAMIDE  |   NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3qgf:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND (2R)-4-(6-CHLOROPYRIDAZIN-3-YL)-N-(4-METHOXYBENZYL)-1-{[4- (TRIFLUOROMETHOXY)PHENYL]SULFONYL}PIPERAZINE-2-CARBOXAMIDE  |   NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3qgf:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND (2R)-4-(6-CHLOROPYRIDAZIN-3-YL)-N-(4-METHOXYBENZYL)-1-{[4- (TRIFLUOROMETHOXY)PHENYL]SULFONYL}PIPERAZINE-2-CARBOXAMIDE  |   NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3qgg:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND N-CYCLOPROPYL-6-[(3R)-3-{[4-(TRIFLUOROMETHOXY)BENZYL]CARBAMOYL}- 4-{[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}PIPERAZIN-1-YL]PYRIDAZINE-3- CARBOXAMIDE  |   NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3qgg:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE COMPLEX WITH (2E)-3-(4-{[(1-{[(13-CYCLOHEXYL-6-OXO-6,7- DIHYDRO-5H-INDOLO[1,2-D][1,4]BENZODIAZEPIN-10-YL) CARBONYL]AMINO}CYCLOPENTYL)CARBONYL]AMINO}PHENYL)PROP-2-ENOIC ACID AND N-CYCLOPROPYL-6-[(3R)-3-{[4-(TRIFLUOROMETHOXY)BENZYL]CARBAMOYL}- 4-{[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}PIPERAZIN-1-YL]PYRIDAZINE-3- CARBOXAMIDE  |   NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3qgh:A    (VAL85) to   (LYS181)  CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE GENOTYPE 1A COMPLEX WITH N-CYCLOPROPYL-6-[(3R)-3-{[4- (TRIFLUOROMETHOXY)BENZYL]CARBAMOYL}-4-{[4-(TRIFLUOROMETHOXY) PHENYL]SULFONYL}PIPERAZIN-1-YL]PYRIDAZINE-3-CARBOXAMIDE  |   NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3qgi:A    (VAL85) to   (LYS181)  CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE GENOTYPE 1A COMPLEX WITH N-[(2S)-BUTAN-2-YL]-6-[(3R)-3- {[4-(TRIFLUOROMETHOXY)BENZYL]CARBAMOYL}-4-{[4-(TRIFLUOROMETHOXY) PHENYL]SULFONYL}PIPERAZIN-1-YL]PYRIDAZINE-3-CARBOXAMIDE  |   NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
5trh:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 2-[(BENZENECARBONYL)AMINO]-3-[(4- CHLOROPHENYL)METHOXY]BENZOIC ACID  |   NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
5trh:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 2-[(BENZENECARBONYL)AMINO]-3-[(4- CHLOROPHENYL)METHOXY]BENZOIC ACID  |   NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
5trk:A    (VAL85) to   (THR181)  CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA- DEPENDENT RNA POLYMERASE IN COMPLEX WITH N-{3-[(BENZENECARBONYL)AMINO]-4-[(4- CHLOROPHENYL)METHOXY]BENZENE-1-CARBONYL}GLYCINE  |   NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
5trk:B    (VAL85) to   (THR181)  CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA- DEPENDENT RNA POLYMERASE IN COMPLEX WITH N-{3-[(BENZENECARBONYL)AMINO]-4-[(4- CHLOROPHENYL)METHOXY]BENZENE-1-CARBONYL}GLYCINE  |   NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
2brk:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH AN ALLOSTERIC INHIBITOR (COMPOUND 1)  |   TRANSFERASE, HEPATITIS C VIRUS, HCV, NS5B, POLYMERASE, RNA-DEPENDENT RNA- POLYMERASE, ALLOSTERIC INHIBITOR, ATP-BINDING 
2brl:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HEPATITIS C VIRUS POLYMERASE IN COMPLEX WITH AN ALLOSTERIC INHIBITOR (COMPOUND 2)  |   TRANSFERASE, HEPATITIS C VIRUS, HCV, NS5B, POLYMERASE, RNA-DEPENDENT RNA- POLYMERASE, ALLOSTERIC INHIBITOR, NUCLEOTIDYLTRANSFERASE 
1os5:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE COMPLEXED WITH A NOVEL NON-COMPETITIVE INHIBITOR.  |   ENZYME-INHIBITOR COMPLEX, TRANSFERASE 
2d41:A    (VAL85) to   (THR181)  X-RAY CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH NON-NUCLEOSIDE INHIBITOR  |   HEPATITIS C VIRUS, RNA POLYMERASE, ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE 
2d41:B    (SER84) to   (THR181)  X-RAY CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH NON-NUCLEOSIDE INHIBITOR  |   HEPATITIS C VIRUS, RNA POLYMERASE, ENZYME INHIBITION, X-RAY CRYSTALLOGRAPHY, TRANSFERASE 
3gol:A    (SER84) to   (THR181)  HCV NS5B POLYMERASE IN COMPLEX WITH 1,5 BENZODIAZEPINE INHIBITOR (R)- 11D  |   1,5-BENZODIAZEPINE, HCV POLYMERASE, NS5B, MEDICINAL CHEMISTRY, 1B-J4, TRANSFERASE 
2dxs:A    (SER84) to   (VAL186)  CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE COMPLEXED WITH A TETRACYCLIC INHIBITOR  |   HCV, NS5B, RNA POLYMERASE, TRANSFERASE/TRANSFERASE INHIBITOR COMPLEX 
2dxs:B    (SER84) to   (GLY188)  CRYSTAL STRUCTURE OF HCV NS5B RNA POLYMERASE COMPLEXED WITH A TETRACYCLIC INHIBITOR  |   HCV, NS5B, RNA POLYMERASE, TRANSFERASE/TRANSFERASE INHIBITOR COMPLEX 
3tyq:A    (ILE85) to   (THR181)  SAR DEVELOPMENT AND DISCOVERY OF POTENT INDOLE-BASED INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE  |   RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3tyq:B    (SER84) to   (THR181)  SAR DEVELOPMENT AND DISCOVERY OF POTENT INDOLE-BASED INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE  |   RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3h5s:A    (VAL85) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B WITH SACCHARIN INHIBITOR  |   HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC 
3h5s:B    (SER84) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B WITH SACCHARIN INHIBITOR  |   HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC 
3h5u:A    (VAL85) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B WITH SACCHARIN INHIBITOR 1  |   HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC 
3h5u:B    (VAL85) to   (THR181)  HEPATITIS C VIRUS POLYMERASE NS5B WITH SACCHARIN INHIBITOR 1  |   HCV, HEPATITIS, NS5B, TRANSFERASE RNA-DEPENDENT RNA POLYMERASE, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CELL MEMBRANE, CYTOPLASM, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC 
4ju2:A    (SER84) to   (MET187)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 12  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4ju2:B    (SER84) to   (VAL186)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 12  |   RNA-DIRECTED RNA POLYMERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3u4o:A    (ILE85) to   (THR181)  NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE C2 ACYL SULFONAMIDES  |   NUCLEOTIDYL TRANSFER, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
3u4o:B    (ILE85) to   (THR181)  NOVEL HCV NS5B POLYMERASE INHIBITORS: DISCOVERY OF INDOLE C2 ACYL SULFONAMIDES  |   NUCLEOTIDYL TRANSFER, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4jy0:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 3  |   TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4jy0:B    (ILE85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH COMPOUND 3  |   TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4k6m:B   (THR397) to   (HIS498)  CRYSTAL STRUCTURE OF THE FULL-LENGTH JAPANESE ENCEPHALITIS VIRUS NS5  |   METHYLTRANSFERASE, RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE 
4khr:B    (SER84) to   (LYS181)  HCV NS5B GT1A C316Y WITH GSK5852  |   HCV POLYMERASE, HCV NS5B, SITE IV INHIBITOR, BORON, P66, P70, RNA DEPENDENT RNA POLYMERASE, RNA DIRECTED RNA POLYMERASE, POLYMERASE, RNS DEPENDENT RNA POLYMERASE, REPLICATION-REPLICATION INHIBITOR COMPLEX 
3hvo:A    (VAL85) to   (LYS181)  STRUCTURE OF THE GENOTYPE 2B HCV POLYMERASE BOUND TO A NNI  |   VIRAL POLYMERASE, ATP-BINDING, HYDROLASE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE 
3hvo:B    (VAL85) to   (LYS181)  STRUCTURE OF THE GENOTYPE 2B HCV POLYMERASE BOUND TO A NNI  |   VIRAL POLYMERASE, ATP-BINDING, HYDROLASE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE 
3i5k:A    (LEU85) to   (LYS181)  CRYSTAL STRUCTURE OF THE NS5B POLYMERASE FROM HEPATITIS C VIRUS (HCV) STRAIN JFH1  |   RDRP STRUCTURE (FINGERS, PALM, THUMB DOMAINS), APOPTOSIS, ATP- BINDING, CAPSID PROTEIN, CELL MEMBRANE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION 
3i5k:B    (LEU85) to   (LYS181)  CRYSTAL STRUCTURE OF THE NS5B POLYMERASE FROM HEPATITIS C VIRUS (HCV) STRAIN JFH1  |   RDRP STRUCTURE (FINGERS, PALM, THUMB DOMAINS), APOPTOSIS, ATP- BINDING, CAPSID PROTEIN, CELL MEMBRANE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION 
3i5k:C    (THR84) to   (LYS181)  CRYSTAL STRUCTURE OF THE NS5B POLYMERASE FROM HEPATITIS C VIRUS (HCV) STRAIN JFH1  |   RDRP STRUCTURE (FINGERS, PALM, THUMB DOMAINS), APOPTOSIS, ATP- BINDING, CAPSID PROTEIN, CELL MEMBRANE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION 
3i5k:D    (LEU85) to   (LYS181)  CRYSTAL STRUCTURE OF THE NS5B POLYMERASE FROM HEPATITIS C VIRUS (HCV) STRAIN JFH1  |   RDRP STRUCTURE (FINGERS, PALM, THUMB DOMAINS), APOPTOSIS, ATP- BINDING, CAPSID PROTEIN, CELL MEMBRANE, DISULFIDE BOND, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA- BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN, VIRION 
2who:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS5B POLYMERASE FROM 1B GENOTYPE IN COMPLEX WITH A NON-NUCLEOSIDE INHIBITOR  |   TRANSFERASE, RNA REPLICATION, ENVELOPE PROTEIN, HEPATITIS C VIRUS, ENDOPLASMIC RETICULUM, NON NUCLEOSIDE INHIBITOR, VIRAL PROTEIN, METAL-BINDING, TRANSMEMBRANE, POLYMERASE, ATP-BINDING, GENOTYPE 1B, RNA-BINDING, RNA-DEPENDENT RNA POLYMERASE, NNI, HCV, NS5B, MEMBRANE, HELICASE, HYDROLASE, NUCLEOTIDE-BINDING, ALLOSTERIC INHIBITOR, RNA-DIRECTED RNA POLYMERASE 
2xhv:B    (ILE85) to   (THR181)  HCV-J4 NS5B POLYMERASE POINT MUTANT ORTHORHOMBIC CRYSTAL FORM  |   REPLICATION, TRANSCRIPTION, TRANSFERASE 
4mz4:A    (ILE85) to   (THR181)  DISCOVERY OF AN IRREVERSIBLE HCV NS5B POLYMERASE INHIBITOR  |   RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4mz4:B    (ILE85) to   (THR181)  DISCOVERY OF AN IRREVERSIBLE HCV NS5B POLYMERASE INHIBITOR  |   RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4oow:A    (ILE85) to   (VAL186)  HCV NS5B POLYMERASE WITH A FRAGMENT OF QUERCETAGETIN  |   ENZYME, TRANSFERASE 
4oow:B    (ILE85) to   (THR181)  HCV NS5B POLYMERASE WITH A FRAGMENT OF QUERCETAGETIN  |   ENZYME, TRANSFERASE 
4aep:A    (LEU85) to   (LYS181)  HCV-JFH1 NS5B POLYMERASE STRUCTURE AT 1.8 ANGSTROM  |   TRANSFERASE, HEPACIVIRUS, NONSTRUCTURAL PROTEINS, REPLICATION, DE NOVO INITIATION, PRIMING 
1yvx:A    (THR84) to   (LYS181)  HEPATITIS C VIRUS RNA POLYMERASE GENOTYPE 2A IN COMPLEX WITH NON- NUCLEOSIDE ANALOGUE INHIBITOR  |   NS5B POLYMERASE GENOTYPE 2A, NON-NUCLEOSIDE INHIBITOR, VIRAL PROTEIN 
3bsc:A    (SER84) to   (GLY188)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR  |   PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN 
3bsc:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR  |   PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, VIRAL NUCLEOPROTEIN 
3cde:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR  |   PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, ATP-BINDING, HOST-VIRUS INTERACTION, HYDROLASE, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RIBONUCLEOPROTEIN, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION 
3cde:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR  |   PROTEIN-LIGAND COMPLEX, RNA REPLICATION, RNA-BINDING, RNA- DIRECTED RNA POLYMERASE, ATP-BINDING, HOST-VIRUS INTERACTION, HYDROLASE, METAL-BINDING, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, RIBONUCLEOPROTEIN, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION 
3cj2:A    (VAL85) to   (THR181)  CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS  |   DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC 
3cj2:B    (VAL85) to   (THR181)  CRYSTAL STRUCTURE OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE NS5B IN COMPLEX WITH OPTIMIZED SMALL MOLECULE FRAGMENTS  |   DRUG DISCOVERY, HCV NS5B, FRAGMENT BASED, ACETYLATION, APOPTOSIS, ATP-BINDING, CAPSID PROTEIN, CYTOPLASM, ENDOPLASMIC RETICULUM, ENVELOPE PROTEIN, FUSION PROTEIN, GLYCOPROTEIN, HELICASE, HOST-VIRUS INTERACTION, HYDROLASE, INTERFERON ANTIVIRAL SYSTEM EVASION, LIPID DROPLET, LIPOPROTEIN, MEMBRANE, METAL-BINDING, MITOCHONDRION, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE, NUCLEUS, ONCOGENE, PALMITATE, PHOSPHOPROTEIN, PROTEASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, SECRETED, SERINE PROTEASE, SH3-BINDING, THIOL PROTEASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UBL CONJUGATION, VIRAL NUCLEOPROTEIN, VIRION, ZINC 
3co9:A    (VAL85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR  |   PROTEIN-LIGAND COMPLEX, NUCLEOTIDE BINDING, NUCLEOTIDYLTRANSFERASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSFERASE, ANTIVIRAL, HYDROLASE, NUCLEOTIDE-BINDING 
3co9:B    (VAL85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR  |   PROTEIN-LIGAND COMPLEX, NUCLEOTIDE BINDING, NUCLEOTIDYLTRANSFERASE, RIBONUCLEOPROTEIN, RNA REPLICATION, RNA-BINDING, RNA-DIRECTED RNA POLYMERASE, TRANSCRIPTION, TRANSFERASE, ANTIVIRAL, HYDROLASE, NUCLEOTIDE-BINDING 
3cvk:A    (VAL85) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR  |   PROTEIN-LIGAND COMPLEX, RNA-DIRECTED RNA POLYMERASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE 
3cvk:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE WITH A NOVEL PYRIDAZINONE INHIBITOR  |   PROTEIN-LIGAND COMPLEX, RNA-DIRECTED RNA POLYMERASE, NUCLEOTIDE-BINDING, NUCLEOTIDYLTRANSFERASE 
4ry6:A    (SER84) to   (TYR191)  C-TERMINAL MUTANT (W550A) OF HCV/J4 RNA POLYMERASE  |   HEPATITIS C VIRUS, REPLICATION, FUNCTION ANALYSIS, VIRAL RNA POLYMERASE, RDRP, RNA RNTP MG, NUCLEOTIDE TRANSFER, TRANSFERASE 
4eo8:A    (SER84) to   (THR181)  HCV NS5B POLYMERASE INHIBITORS: TRI-SUBSTITUTED ACYLHYDRAZINES AS TERTIARY AMIDE BIOISOSTERES  |   HCV, NS5B, RNA, RNA POLYMERASE, POLYMERASE INHIBITOR, THUMB SITE 2 INHIBITOR, RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4eo8:B    (VAL85) to   (THR181)  HCV NS5B POLYMERASE INHIBITORS: TRI-SUBSTITUTED ACYLHYDRAZINES AS TERTIARY AMIDE BIOISOSTERES  |   HCV, NS5B, RNA, RNA POLYMERASE, POLYMERASE INHIBITOR, THUMB SITE 2 INHIBITOR, RNA-DEPENDENT RNA POLYMERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4gmc:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH A THUMB INHIBITOR  |   TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
4gmc:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF HCV NS5B POLYMERASE IN COMPLEX WITH A THUMB INHIBITOR  |   TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
5tri:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 3-[(4-CHLOROPHENYL)METHOXY]-2-(1-OXO-1,3- DIHYDRO-2H-ISOINDOL-2-YL)BENZOIC ACID  |   NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
5tri:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 3-[(4-CHLOROPHENYL)METHOXY]-2-(1-OXO-1,3- DIHYDRO-2H-ISOINDOL-2-YL)BENZOIC ACID  |   NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
5trj:A    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 2-{[2-(CARBOXYMETHOXY)BENZENE-1- CARBONYL]AMINO}-3-[(4-CHLOROPHENYL)METHOXY]BENZOIC ACID  |   NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX 
5trj:B    (SER84) to   (THR181)  CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE IN COMPLEX WITH 2-{[2-(CARBOXYMETHOXY)BENZENE-1- CARBONYL]AMINO}-3-[(4-CHLOROPHENYL)METHOXY]BENZOIC ACID  |   NS5B, POLYMERASE, HCV, FINGERS, PALM, THUMB, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX