2oid:A (CYS259) to (ALA335) CRYSTAL STRUCTURE OF IRAK4 KINASE DOMAIN COMPLEXED WITH AMPPNP | KINASE, TRANSFERASE
4wnk:A (LEU259) to (PRO337) CRYSTAL STRUCTURE OF BOVINE G PROTEIN COUPLED-RECEPTOR KINASE 5 IN COMPLEX WITH CCG215022 | G PROTEIN-COUPLED RECEPTOR KINASE 5, HYDROLASE, PHOSPHORYLATION, CARDIOVASCULAR DISEASE, LIGASE
4wnp:B (SER87) to (GLN173) STRUCTURE OF ULK1 BOUND TO A POTENT INHIBITOR | KINASE, AUTOPHAGY, INHIBITOR
4wnp:C (GLU93) to (GLN173) STRUCTURE OF ULK1 BOUND TO A POTENT INHIBITOR | KINASE, AUTOPHAGY, INHIBITOR
2ou7:A (GLU131) to (TYR203) STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN POLO-LIKE KINASE 1 | KINASE DOMAIN, TRANSFERASE
2owb:A (GLU131) to (TYR203) STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN POLO-LIKE KINASE 1 | CATALYTIC DOMAIN, PLK1, POLO-LIKE KINASE1, KINASE, TRANSFERASE
2oza:A (LEU134) to (THR214) STRUCTURE OF P38ALPHA COMPLEX | SERINE/THREONINE KINASE, PROTEIN-PROTEIN COMPLEX, P38A, MK2, SIGNALING PROTEIN/TRANSFERASE COMPLEX
2b9h:A (ASN87) to (ILE162) CRYSTAL STRUCTURE OF FUS3 WITH A DOCKING MOTIF FROM STE7 | TRANSFERASE
2b9i:A (GLU88) to (ILE162) CRYSTAL STRUCTURE OF FUS3 WITH A DOCKING MOTIF FROM MSG5 | TRANSFERASE
1o6y:A (GLY85) to (ILE163) CATALYTIC DOMAIN OF PKNB KINASE FROM MYCOBACTERIUM TUBERCULOSIS | SERINE/THREONINE PROTEIN KINASE, TRANSFERASE, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TB, TBSGC
4hok:W (ASN78) to (ARG157) CRYSTAL STRUCTURE OF APO CK1E | CK1E, KINASE, INHIBITOR, PF 4800567, TRANSFERASE
3f7z:A (GLU125) to (GLN206) X-RAY CO-CRYSTAL STRUCTURE OF GLYCOGEN SYNTHASE KINASE 3BETA IN COMPLEX WITH AN INHIBITOR | ENZYME, PROTEIN KINASE, INHIBITOR CO-CRYSTAL STRUCTURE, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, WNT SIGNALING PATHWAY
3f7z:B (LEU128) to (GLN206) X-RAY CO-CRYSTAL STRUCTURE OF GLYCOGEN SYNTHASE KINASE 3BETA IN COMPLEX WITH AN INHIBITOR | ENZYME, PROTEIN KINASE, INHIBITOR CO-CRYSTAL STRUCTURE, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, WNT SIGNALING PATHWAY
3say:B (GLU125) to (GLN206) CRYSTAL STRUCTURE OF HUMAN GLYCOGEN SYNTHASE KINASE 3 BETA (GSK3B) IN COMPLEX WITH INHIBITOR 142 | KINASE, ATP HYDROLYSIS, PHOSPHORYLATION, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4xbu:A (LEU391) to (SER466) IN VITRO CRYSTAL STRUCTURE OF PAK4 IN COMPLEX WITH INKA PEPTIDE | PAK4, INKA, TRANSFERASE-PEPTIDE COMPLEX
4hvd:A (LEU898) to (LEU976) JAK3 KINASE DOMAIN IN COMPLEX WITH 2-CYCLOPROPYL-5H-PYRROLO[2,3- B]PYRAZINE-7-CARBOXYLIC ACID ((S)-1,2,2-TRIMETHYL-PROPYL)-AMIDE | KINASE-INHIBITOR COMPLEX, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4hvh:A (LEU898) to (PRO975) JAK3 KINASE DOMAIN IN COMPLEX WITH 2-CYCLOPROPYL-5H-PYRROLO[2,3- B]PYRAZINE-7-CARBOXYLIC ACID ((R)-2-HYDROXY-1,2-DIMETHYL-PROPYL | KINASE-INHIBITOR COMPLEX, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4hvi:A (LEU898) to (PRO975) JAK3 KINASE DOMAIN IN COMPLEX WITH 2-CYCLOPROPYL-5H-PYRROLO[2,3- B]PYRAZINE-7-CARBOXYLIC ACID ((R)-1-METHYL-2-OXO-2-PIPERIDIN-1-YL- ETHYL)-AMIDE | KINASE-INHIBITOR COMPLEX, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3fdn:A (GLU211) to (VAL279) STRUCTURE-BASED DRUG DESIGN OF NOVEL AURORA KINASE A INHIBITORS: STRUCTURE BASIS FOR POTENCY AND SPECIFICITY | AURORA KINASE INHIBITORS, VIRTUAL SCREENING, X-RAY CO- CRYSTAL ANALYSIS, STRUCTURE-BASED DRUG DESIGN (SBDD), H- BONDING., ATP-BINDING, CELL CYCLE, KINASE, NUCLEOTIDE- BINDING, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE- PROTEIN KINASE, TRANSFERASE
3ffe:A (GLY365) to (THR471) STRUCTURE OF ACHROMOBACTIN SYNTHETASE PROTEIN D, (ACSD) | ACSD, ADENYLATING ENZYME, SIDEROPHORE, STRUCTURAL GENOMICS, SCOTTISH STRUCTURAL PROTEOMICS FACILITY, SSPF, BIOSYNTHETIC PROTEIN
3ffe:B (GLY365) to (THR471) STRUCTURE OF ACHROMOBACTIN SYNTHETASE PROTEIN D, (ACSD) | ACSD, ADENYLATING ENZYME, SIDEROPHORE, STRUCTURAL GENOMICS, SCOTTISH STRUCTURAL PROTEOMICS FACILITY, SSPF, BIOSYNTHETIC PROTEIN
2pmi:A (ASN76) to (GLY159) STRUCTURE OF THE PHO85-PHO80 CDK-CYCLIN COMPLEX OF THE PHOSPHATE- RESPONSIVE SIGNAL TRANSDUCTION PATHWAY WITH BOUND ATP-GAMMA-S | CYCLIN-DEPENDENT KINASE, CYCLIN, SIGNALING PROTEIN,TRANSFERASE-CELL CYCLE COMPLEX
2c30:A (LEU477) to (SER552) CRYSTAL STRUCTURE OF THE HUMAN P21-ACTIVATED KINASE 6 | CRIB DOMAIN, ATP-BINDING, TRANSFERASE, NUCLEOTIDE-BINDING
1omw:A (LEU267) to (SER343) CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN G PROTEIN-COUPLED RECEPTOR KINASE 2 AND HETEROTRIMERIC G PROTEIN BETA 1 AND GAMMA 2 SUBUNITS | WD-40 REPEAT, TRANSFERASE
4i5c:A (GLY951) to (THR1030) THE JAK1 KINASE DOMAIN IN COMPLEX WITH INHIBITOR | KINASE, TRANSFERASE
2pvy:B (LEU560) to (ASN652) CRYSTAL STRUCURE OF FGF RECEPTOR 2 (FGFR2) KINASE DOMAIN HARBORING THE PATHOGENIC K659N MUTATION RESPONSIBLE FOR AN UNCLASSIFIED CRANIOSYNOSTOSIS SYNDROME. | KINASE DOMAIN FOLD CONSISTING OF N- AND C-LOBES, TRANSFERASE
4i6q:A (LEU898) to (LEU976) JAK3 KINASE DOMAIN IN COMPLEX WITH 2-PHENOXY-5H-PYRROLO[2,3- B]PYRAZINE-7-CARBOXYLIC ACID ((S)-1-CYCLOPROPYL-ETHYL)-AMIDE | KINASE-INHIBITOR COMPLEX, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ian:A (LEU763) to (HIS840) CRYSTAL STRUCTURE OF APO HUMAN PRPF4B KINASE DOMAIN | KINASE, TRANSFERASE
4ian:B (LEU763) to (HIS840) CRYSTAL STRUCTURE OF APO HUMAN PRPF4B KINASE DOMAIN | KINASE, TRANSFERASE
4ic7:A (LYS131) to (LEU207) CRYSTAL STRUCTURE OF THE ERK5 KINASE DOMAIN IN COMPLEX WITH AN MKK5 BINDING FRAGMENT | KINASE DOMAIN, SIGNALING PROTEIN COMPLEX, TRANSFERASE
1ctp:E (LEU116) to (ARG190) STRUCTURE OF THE MAMMALIAN CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE AND AN INHIBITOR PEPTIDE DISPLAYS AN OPEN CONFORMATION | TRANSFERASE(PHOSPHOTRANSFERASE), TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ifc:A (LEU763) to (HIS840) CRYSTAL STRUCTURE OF ADP-BOUND HUMAN PRPF4B KINASE DOMAIN | KINASE, TRANSFERASE
4ifc:B (LEU763) to (HIS840) CRYSTAL STRUCTURE OF ADP-BOUND HUMAN PRPF4B KINASE DOMAIN | KINASE, TRANSFERASE
4iir:A (LEU763) to (ALA842) CRYSTAL STRUCTURE OF AMPPNP-BOUND HUMAN PRPF4B KINASE DOMAIN | KINASE, TRANSFERASE
4iir:B (LEU763) to (HIS840) CRYSTAL STRUCTURE OF AMPPNP-BOUND HUMAN PRPF4B KINASE DOMAIN | KINASE, TRANSFERASE
4ijp:A (LEU763) to (HIS840) CRYSTAL STRUCTURE OF HUMAN PRPF4B KINASE DOMAIN IN COMPLEX WITH 4-{5- [(2-CHLORO-PYRIDIN-4-YLMETHYL)-CARBAMOYL]-THIOPHEN-2-YL}- BENZO[B]THIOPHENE-2-CARBOXYLIC ACID AMINE | KINASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ijp:B (LEU763) to (HIS840) CRYSTAL STRUCTURE OF HUMAN PRPF4B KINASE DOMAIN IN COMPLEX WITH 4-{5- [(2-CHLORO-PYRIDIN-4-YLMETHYL)-CARBAMOYL]-THIOPHEN-2-YL}- BENZO[B]THIOPHENE-2-CARBOXYLIC ACID AMINE | KINASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1pkg:A (GLU671) to (LYS818) STRUCTURE OF A C-KIT KINASE PRODUCT COMPLEX | KINASE, AUTOPHOSPHORYLATION, TRANSACTIVATION, TRANSFERASE ACTIVATOR
4ivb:B (GLY951) to (THR1030) JAK1 KINASE (JH1 DOMAIN) IN COMPLEX WITH THE INHIBITOR TRANS-4-{2- [(1R)-1-HYDROXYETHYL]IMIDAZO[4,5-D]PYRROLO[2,3-B]PYRIDIN-1(6H)- YL}CYCLOHEXANECARBONITRILE | PROTEIN KINASE, PHOSPHOTRANSFER, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ivd:A (GLY951) to (THR1030) JAK1 KINASE (JH1 DOMAIN) IN COMPLEX WITH COMPOUND 34 | PROTEIN KINASE, PHOSPHO TRANSFER, PHOSPHO TYROSINE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ivd:B (GLY951) to (THR1030) JAK1 KINASE (JH1 DOMAIN) IN COMPLEX WITH COMPOUND 34 | PROTEIN KINASE, PHOSPHO TRANSFER, PHOSPHO TYROSINE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4j52:A (GLU131) to (TYR203) CRYSTAL STRUCTURE OF PLK1 IN COMPLEX WITH A PYRIMIDODIAZEPINONE INHIBITOR | PROTEIN SERINE/THREONINE KINASE, MITOSIS, ONCOGENESIS, REGULATION OF CELL CYCLE, KINASE DOMAIN, ATP BINDING, NUCLEAR, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
4j71:A (ASP124) to (GLN206) CRYSTAL STRUCTURE OF GSK3B IN COMPLEX WITH INHIBITOR 1R | STRUCTURAL GENOMICS, PSI-BIOLOGY, NEW YORK STRUCTURAL GENOMICS RESEARCH CONSORTIUM, NYSGRC, KINASE, PHOSPHORYLATION, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
1q3w:A (GLU125) to (GLN206) GSK-3 BETA COMPLEXED WITH ALSTERPAULLONE | KINASE, INSULIN PATHWAY, ALSTERPAULLONE, TRANSFERASE
1q3w:B (GLU125) to (GLN206) GSK-3 BETA COMPLEXED WITH ALSTERPAULLONE | KINASE, INSULIN PATHWAY, ALSTERPAULLONE, TRANSFERASE
1q41:A (LEU128) to (GLN206) GSK-3 BETA COMPLEXED WITH INDIRUBIN-3'-MONOXIME | KINASE, INSULIN PATHWAY, INDIRUBIN-3'-MONOXIME, TRANSFERASE
1q5k:A (ASP124) to (GLN206) CRYSTAL STRUCTURE OF GLYCOGEN SYNTHASE KINASE 3 IN COMPLEXED WITH INHIBITOR | KINASE-INHIBITOR COMPLEX, TRANSFERASE
3tku:B (LEU149) to (MET225) MRCK BETA IN COMPLEX WITH FASUDIL | PROTEIN KINASE, SERINE THREONINE KINASE, MRCK, MRCK BETA, CD BINDING PROTEIN KINASE BETA, FASUDIL, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4jdi:A (MET395) to (SER466) CRYSTAL STRUCTURE OF SERINE/THREONINE-PROTEIN KINASE PAK 4 IN COMPLEX WITH PAKTIDE S PEPTIDE SUBSTRATE | TRANSFERASE-PEPTIDE COMPLEX, TRANSFERASE/PEPTIDE, SERINE/THREONINE- PROTEIN KINASE PAK4, ATP BINDING, PHOSPHORYLATION
4jdj:A (MET395) to (SER466) CRYSTAL STRUCTURE OF SERINE/THREONINE-PROTEIN KINASE PAK 4 F461V MUTANT IN COMPLEX WITH PAKTIDE T PEPTIDE SUBSTRATE | TRANSFERASE-PEPTIDE COMPLEX, TRANSFERASE/PEPTIDE, SERINE/THREONINE- PROTEIN KINASE PAK4, ATP BINDING, PHOSPHORYLATION
4jdk:A (MET395) to (SER466) CRYSTAL STRUCTURE OF SERINE/THREONINE-PROTEIN KINASE PAK 4 F461V MUTANT IN COMPLEX WITH PAKTIDE S PEPTIDE SUBSTRATE | TRANSFERASE-PEPTIDE COMPLEX, TRANSFERASE/PEPTIDE, SERINE/THREONINE- PROTEIN KINASE PAK4, ATP BINDING, PHOSPHORYLATION
1q8y:A (GLY239) to (TYR557) THE STRUCTURE OF THE YEAST SR PROTEIN KINASE, SKY1P, WITH BOUND ADP | PROTEIN KINASE, TRANSFERASE
1q8y:B (GLY239) to (TRP556) THE STRUCTURE OF THE YEAST SR PROTEIN KINASE, SKY1P, WITH BOUND ADP | PROTEIN KINASE, TRANSFERASE
1q8z:A (GLY239) to (TRP556) THE APOENZYME STRUCTURE OF THE YEAST SR PROTEIN KINASE, SKY1P | DISALLOWED, KINASE, TRANSFERASE
1q8z:B (GLY239) to (TRP556) THE APOENZYME STRUCTURE OF THE YEAST SR PROTEIN KINASE, SKY1P | DISALLOWED, KINASE, TRANSFERASE
1q99:A (GLY239) to (TRP556) CRYSTAL STRUCTURE OF THE SACCHAROMYCES CEREVISIAE SR PROTEIN KINSAE, SKY1P, COMPLEXED WITH THE NON-HYDROLYZABLE ATP ANALOGUE, AMP-PNP | PROTEIN KINASE, TRANSFERASE
1q99:B (GLY239) to (TRP556) CRYSTAL STRUCTURE OF THE SACCHAROMYCES CEREVISIAE SR PROTEIN KINSAE, SKY1P, COMPLEXED WITH THE NON-HYDROLYZABLE ATP ANALOGUE, AMP-PNP | PROTEIN KINASE, TRANSFERASE
4yhj:B (LEU260) to (GLU339) STRUCTURE AND FUNCTION OF THE HYPERTENSION VARIANT A486V OF G PROTEIN- COUPLED RECEPTOR KINASE 4 (GRK4) | TRANSFERASE
4jr7:A (PRO148) to (PHE220) CRYSTAL STRUCTURE OF SCCK2 ALPHA IN COMPLEX WITH GMPPNP | PROTEIN KINASE, PROTEIN PHOSPHORYLATION, TRANSFERASE
2euf:B (THR92) to (ILE169) X-RAY STRUCTURE OF HUMAN CDK6-VCYCLIN IN COMPLEX WITH THE INHIBITOR PD0332991 | INHIBITOR COMPLEX OF HUMAN CYCLIN-DEPENDENT KINASE 6, CELL CYCLE- TRANSFERASE COMPLEX
4ysm:A (PHE101) to (HIS178) CALCIUM-DEPENDENT PROTEIN KINASE FROM EIMERIA TENELLA | SERINE/THREONINE PROTEIN KINASE, TRANSFERASE, CALCIUM-BINDING, ATP- BINDING
4ysm:B (PHE101) to (HIS178) CALCIUM-DEPENDENT PROTEIN KINASE FROM EIMERIA TENELLA | SERINE/THREONINE PROTEIN KINASE, TRANSFERASE, CALCIUM-BINDING, ATP- BINDING
4yth:A (LEU925) to (LEU1001) DISCOVERY OF VX-509 (DECERNOTINIB): A POTENT AND SELECTIVE JANUS KINASE (JAK) 3 INHIBITOR FOR THE TREATMENT OF AUTOIMMUNE DISEASES | JAK3 KINASE, JAK2 KINASE, INHIBITOR, AUTOIMMUNE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
4k77:B (GLY951) to (THR1030) JAK1 KINASE (JH1 DOMAIN) IN COMPLEX WITH COMPOUND 6 | PROTEIN KINASE, PHOSPHOTRANSFER, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4yu2:C (LEU234) to (GLN313) CRYSTAL STRUCTURE OF DYRK1A WITH HARMINE-DERIVATIZED ANNH-75 INHIBITOR | TRANSFERASE, DYRK1A, DOWN SYNDROME, INHIBITOR, HARMINE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC
4yu2:D (LEU234) to (GLN313) CRYSTAL STRUCTURE OF DYRK1A WITH HARMINE-DERIVATIZED ANNH-75 INHIBITOR | TRANSFERASE, DYRK1A, DOWN SYNDROME, INHIBITOR, HARMINE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC
2f49:B (ASN87) to (ILE161) CRYSTAL STRUCTURE OF FUS3 IN COMPLEX WITH A STE5 PEPTIDE | PROTEIN-PETIDE COMPLEX, TRANSFERASE
2fa2:A (ASN87) to (ILE162) CRYSTAL STRUCTURE OF FUS3 WITHOUT A PEPTIDE FROM STE5 | MAP KINASE, TRANSFERASE
4z16:A (LEU898) to (LEU974) CRYSTAL STRUCTURE OF THE JAK3 KINASE DOMAIN COVALENTLY BOUND TO N-(3- (((5-CHLORO-2-((2-METHOXY-4-(4-METHYLPIPERAZIN-1-YL)PHENYL)AMINO) PYRIMIDIN-4-YL)AMINO)METHYL)PHENYL)ACRYLAMIDE | TYROSINE KINASE, KINASE DOMAIN, COVALENT INHIBITOR COMPLEX, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4z16:B (LEU898) to (LEU973) CRYSTAL STRUCTURE OF THE JAK3 KINASE DOMAIN COVALENTLY BOUND TO N-(3- (((5-CHLORO-2-((2-METHOXY-4-(4-METHYLPIPERAZIN-1-YL)PHENYL)AMINO) PYRIMIDIN-4-YL)AMINO)METHYL)PHENYL)ACRYLAMIDE | TYROSINE KINASE, KINASE DOMAIN, COVALENT INHIBITOR COMPLEX, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4z16:C (LEU898) to (LEU974) CRYSTAL STRUCTURE OF THE JAK3 KINASE DOMAIN COVALENTLY BOUND TO N-(3- (((5-CHLORO-2-((2-METHOXY-4-(4-METHYLPIPERAZIN-1-YL)PHENYL)AMINO) PYRIMIDIN-4-YL)AMINO)METHYL)PHENYL)ACRYLAMIDE | TYROSINE KINASE, KINASE DOMAIN, COVALENT INHIBITOR COMPLEX, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4z16:D (LEU898) to (LEU974) CRYSTAL STRUCTURE OF THE JAK3 KINASE DOMAIN COVALENTLY BOUND TO N-(3- (((5-CHLORO-2-((2-METHOXY-4-(4-METHYLPIPERAZIN-1-YL)PHENYL)AMINO) PYRIMIDIN-4-YL)AMINO)METHYL)PHENYL)ACRYLAMIDE | TYROSINE KINASE, KINASE DOMAIN, COVALENT INHIBITOR COMPLEX, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3uo4:A (GLU211) to (ALA281) AURORA A IN COMPLEX WITH RPM1680 | PROTEIN KINASE, AURORA A, INHIBITOR, DFG-IN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4kik:B (PRO92) to (LEU173) HUMAN IKB KINASE BETA | KINASE, NKB SIGNALING, TRANSFERASE
2vgo:B (ILE166) to (PRO242) CRYSTAL STRUCTURE OF AURORA B KINASE IN COMPLEX WITH REVERSINE INHIBITOR | NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, ATP-BINDING, TRANSFERASE, COILED COIL, CELL DIVISION, KINASE, CANCER, INCENP, NUCLEUS, MITOSIS, AURORA B, METAL-BINDING, AMINOTHIAZOLE, PHOSPHORYLATION, MAGNESIUM, CELL CYCLE, CENTROMERE, MICROTUBULE
2fum:A (GLY85) to (ILE163) CATALYTIC DOMAIN OF PROTEIN KINASE PKNB FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH MITOXANTRONE | PROTEIN KINASE-INHIBITOR COMPLEX, TRANSFERASE
2fum:B (GLY85) to (ILE163) CATALYTIC DOMAIN OF PROTEIN KINASE PKNB FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH MITOXANTRONE | PROTEIN KINASE-INHIBITOR COMPLEX, TRANSFERASE
4krd:A (LEU78) to (PHE158) CRYSTAL STRUCTURE OF PHO85-PCL10 COMPLEX | GLYCOGEN SYNTHESIS, CDK, CYCLIN, GLYCOGEN SYNTHESIS REGULATION, TRANSFERASE-SIGNALING PROTEIN COMPLEX
2vrx:B (ILE166) to (PRO242) STRUCTURE OF AURORA B KINASE IN COMPLEX WITH ZM447439 | SERINE/THREONINE-PROTEIN KINASE, KINASE, NUCLEUS, MITOSIS, MAGNESIUM, CELL CYCLE/TRANSFERASE, CENTROMERE, MICROTUBULE, ATP-BINDING, TRANSFERASE, ANTI-CANCER DRUG TARGET, PHOSPHOPROTEIN, PROTEIN KINASE, NUCLEOTIDE-BINDING, COILED COIL, CELL DIVISION, METAL-BINDING
4zhx:C (ASP88) to (ASP166) NOVEL BINDING SITE FOR ALLOSTERIC ACTIVATION OF AMPK | TRANSFERASE, SERINE/THREONINE KINASE, ALLOSTERIC ACTIVATION, NUCLEOTIDE-BINDING
2gcd:B (ALA101) to (MET176) TAO2 KINASE DOMAIN-STAUROSPORINE STRUCTURE | TAO2, MAP3K, INHIBITOR, STAUROSPORINE, CRYSTAL STRUCTURE, TRANSFERASE
1szm:A (LEU116) to (ARG190) DUAL BINDING MODE OF BISINDOLYLMALEIMIDE 2 TO PROTEIN KINASE A (PKA) | PKA, PKC, BISINDOLYL MALEIMIDE 2, LY333531, SELECTIVITY, SURROGATE KINASE, AMINO ACID RESIDUE EXCHANGE, X-RAY STRUCTURE, TRANSFERASE
4zlo:B (VAL342) to (THR415) SERINE/THREONINE-PROTEIN KINASE PAK1 COMPLEXED WITH A DIBENZODIAZEPINE: IDENTIFICATION OF AN ALLOSTERIC SITE ON PAK1 | DIBENZODAZEPINE, PAK1, KINASE, ALLOSTERIC INHIBITOR, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
2w02:A (GLY365) to (ASP473) CO-COMPLEX STRUCTURE OF ACHROMOBACTIN SYNTHETASE PROTEIN D ( ACSD) WITH ATP FROM PECTOBACTERIUM CHRYSANTHEMI | SSPF, ACSD, ACHROMOBACTIN BIOSYNTHESIS, METAL TRANSPORT, PECTOBACTERIUM CHRYSANTHEMI
2w1f:A (VAL206) to (HIS280) STRUCTURE DETERMINATION OF AURORA KINASE IN COMPLEX WITH INHIBITOR | CANCER, AURORA, KINASE, INHIBITOR, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, ATP-BINDING, POLYMORPHISM, PHOSPHOPROTEIN, CELL CYCLE
4zsg:A (LYS131) to (LEU207) MITOGEN ACTIVATED PROTEIN KINASE 7 IN COMPLEX WITH INHIBITOR | KINASE, INHIBITOR
4zsj:A (LYS131) to (LEU207) MITOGEN ACTIVATED PROTEIN KINASE 7 IN COMPLEX WITH INHIBITOR | KINASE, INHIBITOR, TRANSFERASE
4zsl:A (LYS131) to (LEU207) MITOGEN ACTIVATED PROTEIN KINASE 7 IN COMPLEX WITH INHIBITOR | KINASE, INHIBITOR, TRANSFERASE
2h96:A (ASP103) to (ALA176) DISCOVERY OF POTENT, HIGHLY SELECTIVE, AND ORALLY BIOAVAILABLE PYRIDINE CARBOXAMIDE C-JUN NH2-TERMINAL KINASE INHIBITORS | JNK1, C-JUN N-TERMINAL KINASE, PROTEIN KINASE JNK1 INHIBITORS, PYRIDINE CARBOXAMIDE INHIBITORS, TRANSCRIPTION
1how:A (GLY239) to (TRP556) THE X-RAY CRYSTAL STRUCTURE OF SKY1P, AN SR PROTEIN KINASE IN YEAST | KINASE, TRANSFERASE
2wev:A (LEU76) to (GLY153) TRUNCATION AND OPTIMISATION OF PEPTIDE INHIBITORS OF CDK2, CYCLIN A THROUGH STRUCTURE GUIDED DESIGN | CDK2, KINASE, CYCLIN, ACTIVE, NUCLEUS, MITOSIS, SERINE/THREONINE-PROTEIN KINASE, CYTOPLASM, INHIBITION, CELL CYCLE, ATP-BINDING, CELL DIVISION, PHOSPHOPROTEIN, NUCLEOTIDE-BINDING, TRANSFERASE, POLYMORPHISM, BETA-PEPTIDE, CYCLIN GROOVE
1i09:A (LEU128) to (GLN206) STRUCTURE OF GLYCOGEN SYNTHASE KINASE-3 (GSK3B) | KINASE, BETA BARREL, TRANSFERASE
3vw6:B (ILE750) to (ARG828) CRYSTAL STRUCTURE OF HUMAN APOPTOSIS SIGNAL-REGULATING KINASE 1 (ASK1) WITH IMIDAZOPYRIDINE INHIBITOR | TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3w16:A (GLU211) to (VAL279) STRUCTURE OF AURORA KINASE A COMPLEXED TO PYRAZOLE-AMINOQUINOLINE INHIBITOR III | KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1u5q:A (ALA101) to (MET176) CRYSTAL STRUCTURE OF THE TAO2 KINASE DOMAIN: ACTIVATION AND SPECIFITY OF A STE20P MAP3K | SERINE/THREONINE PROTEIN KINASE, TRANSFERASE
1u5r:A (ALA101) to (MET176) CRYSTAL STRUCTURE OF THE TAO2 KINASE DOMAIN: ACTIVATION AND SPECIFITY OF A STE20P MAP3K | SERINE/THREONINE PROTEIN KINASE, TRANSFERASE
5a3x:B (LEU234) to (LEU314) DYRK1A IN COMPLEX WITH HYDROXY BENZOTHIAZOLE FRAGMENT | TRANSFERASE, PROTEIN KINASE,
5a3x:C (LEU234) to (LEU314) DYRK1A IN COMPLEX WITH HYDROXY BENZOTHIAZOLE FRAGMENT | TRANSFERASE, PROTEIN KINASE,
5a4e:B (LEU234) to (LEU314) DYRK1A IN COMPLEX WITH METHOXY BENZOTHIAZOLE FRAGMENT | TRANSFERASE
5a4e:D (LEU234) to (GLN313) DYRK1A IN COMPLEX WITH METHOXY BENZOTHIAZOLE FRAGMENT | TRANSFERASE
5a4q:B (LEU234) to (LEU314) DYRK1A IN COMPLEX WITH CHLORO BENZOTHIAZOLE FRAGMENT | TRANSFERASE
5a4q:C (LEU234) to (LEU314) DYRK1A IN COMPLEX WITH CHLORO BENZOTHIAZOLE FRAGMENT | TRANSFERASE
5a4q:D (LEU234) to (GLN313) DYRK1A IN COMPLEX WITH CHLORO BENZOTHIAZOLE FRAGMENT | TRANSFERASE
5a4t:B (LEU234) to (GLN313) DYRK1A IN COMPLEX WITH NITRILE BENZOTHIAZOLE FRAGMENT | TRANSFERASE
5a4t:C (LEU234) to (LEU314) DYRK1A IN COMPLEX WITH NITRILE BENZOTHIAZOLE FRAGMENT | TRANSFERASE
5a4t:D (LEU234) to (GLN313) DYRK1A IN COMPLEX WITH NITRILE BENZOTHIAZOLE FRAGMENT | TRANSFERASE
5a54:B (LEU234) to (LEU314) DYRK1A IN COMPLEX WITH NITRO BENZOTHIAZOLE FRAGMENT | TRANSFERASE
5a54:C (LEU234) to (LEU314) DYRK1A IN COMPLEX WITH NITRO BENZOTHIAZOLE FRAGMENT | TRANSFERASE
5a54:D (LEU234) to (GLN313) DYRK1A IN COMPLEX WITH NITRO BENZOTHIAZOLE FRAGMENT | TRANSFERASE
3war:A (PRO109) to (PHE181) CRYSTAL STRUCTURE OF HUMAN CK2A | PROTEIN KINASE, TRANSFERASE
1j1b:A (ASP124) to (GLN206) BINARY COMPLEX STRUCTURE OF HUMAN TAU PROTEIN KINASE I WITH AMPPNP | COMPLEX, TAU, KINASE, AMPPNP, TRANSFERASE
2x4z:A (LEU391) to (SER466) CRYSTAL STRUCTURE OF THE HUMAN P21-ACTIVATED KINASE 4 IN COMPLEX WITH PF-03758309 | TRANSFERASE, NUCLEOTIDE-BINDING ATP-BINDING, PHOSPHOPROTEIN
5air:B (ASP124) to (GLN206) STRUCTURAL ANALYSIS OF MOUSE GSK3BETA FUSED WITH LRP6 PEPTIDE. | TRANSFERASE, LRP6, GSK3 BETA
2itw:A (VAL786) to (ALA864) CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN IN COMPLEX WITH AFN941 | RECEPTOR, CELL CYCLE, ATP-BINDING, TRANSFERASE, TRANSMEMBRANE, PHOSPHORYLATION, DISEASE MUTATION, POLYMORPHISM, GLYCOPROTEIN, ANTI-ONCOGENE, NUCLEOTIDE- BINDING, ALTERNATIVE SPLICING, AFN941, EGFR, KINASE, STAUROSPORINE, MEMBRANE, TYROSINE-PROTEIN KINASE, EPIDERMAL GROWTH FACTOR
4mk0:A (LEU267) to (SER343) CRYSTAL STRUCTURE OF G PROTEIN-COUPLED RECEPTOR KINASE 2 IN COMPLEX WITH A A RATIONALLY DESIGNED PAROXETINE DERIVATIVE | INHIBITOR COMPLEX, PROTEIN KINASE, HYDROLASE, ATP BINDING, PHOSPHORYLATION, PERIPHERAL MEMBRANE PROTEIN, SIGNALING PROTEIN- INHIBITOR COMPLEX
2xa4:B (LEU925) to (GLN1003) INHIBITORS OF JAK2 KINASE DOMAIN | KINASE, MEMBRANE, TRANSFERASE, ATP-BINDING, PROTO-ONCOGENE, PHOSPHOPROTEIN
4mq1:B (LEU234) to (LEU314) THE CRYSTAL STRUCTURE OF DYRK1A WITH A BOUND PYRIDO[2,3-D]PYRIMIDINE INHIBITOR | DYRK1A, DYRK1B, KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mq1:D (LEU234) to (LEU314) THE CRYSTAL STRUCTURE OF DYRK1A WITH A BOUND PYRIDO[2,3-D]PYRIMIDINE INHIBITOR | DYRK1A, DYRK1B, KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mq2:A (LEU234) to (GLN313) THE CRYSTAL STRUCTURE OF DYRK1A WITH A BOUND PYRIDO[2,3-D]PYRIMIDINE INHIBITOR | DYRK1A, DYRK1B, KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mq2:B (LEU234) to (GLN313) THE CRYSTAL STRUCTURE OF DYRK1A WITH A BOUND PYRIDO[2,3-D]PYRIMIDINE INHIBITOR | DYRK1A, DYRK1B, KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mq2:C (LEU234) to (GLN313) THE CRYSTAL STRUCTURE OF DYRK1A WITH A BOUND PYRIDO[2,3-D]PYRIMIDINE INHIBITOR | DYRK1A, DYRK1B, KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4mq2:D (LEU234) to (GLN313) THE CRYSTAL STRUCTURE OF DYRK1A WITH A BOUND PYRIDO[2,3-D]PYRIMIDINE INHIBITOR | DYRK1A, DYRK1B, KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2j50:A (GLU211) to (VAL279) STRUCTURE OF AURORA-2 IN COMPLEX WITH PHA-739358 | TRANSFERASE, PHOSPHORYLATION, NUCLEOTIDE-BINDING, KINASE, CELL CYCLE, ATP-BINDING, NUCLEOTIDE- BINDING, SERINE/THREONINE-PROTEIN KINASE, SERINE-THREONINE-PROTEIN KINASE
2j50:B (GLU211) to (VAL279) STRUCTURE OF AURORA-2 IN COMPLEX WITH PHA-739358 | TRANSFERASE, PHOSPHORYLATION, NUCLEOTIDE-BINDING, KINASE, CELL CYCLE, ATP-BINDING, NUCLEOTIDE- BINDING, SERINE/THREONINE-PROTEIN KINASE, SERINE-THREONINE-PROTEIN KINASE
2jd5:A (GLY239) to (TRP556) SKY1P BOUND TO NPL3P-DERIVED SUBSTRATE PEPTIDE | MRNA EXPORT PROTEIN, SERINE/THREONINE-PROTEIN KINASE, KINASE, TRANSFERASE, ATP-BINDING, NUCLEOTIDE-BINDING
3zc6:C (LEU898) to (LEU974) CRYSTAL STRUCTURE OF JAK3 KINASE DOMAIN IN COMPLEX WITH AN INDAZOLE SUBSTITUTED PYRROLOPYRAZINE INHIBITOR | TRANSFERASE, SCID, SEVERE COMBINED IMMUNODEFICIENCY, STAT5, STAT6, INTERLEUKIN-2, COMMON-GAMMA CHAIN, ATP SITE KINASE INHIBITOR, CANCER
3zc6:D (LEU898) to (LEU976) CRYSTAL STRUCTURE OF JAK3 KINASE DOMAIN IN COMPLEX WITH AN INDAZOLE SUBSTITUTED PYRROLOPYRAZINE INHIBITOR | TRANSFERASE, SCID, SEVERE COMBINED IMMUNODEFICIENCY, STAT5, STAT6, INTERLEUKIN-2, COMMON-GAMMA CHAIN, ATP SITE KINASE INHIBITOR, CANCER
3zdi:A (GLU125) to (GLN206) GLYCOGEN SYNTHASE KINASE 3 BETA COMPLEXED WITH AXIN PEPTIDE AND INHIBITOR 7D | TRANSFERASE-PEPTIDE COMPLEX, INSULIN PATHWAY, WNT SIGNALING PATHWAY, TRANSFERASE SERINE/THREONINE-PROTEIN KINASE, INHIBITOR
2jii:A (ARG255) to (CYS334) STRUCTURE OF VACCINIA RELATED KINASE 3 | TRANSFERASE, PSEUDO KINASE DOMAIN, VACCINIA RELATED KINASE, SERINE/THREONINE-PROTEIN KINASE, VRK3, KINASE, ATP-BINDING, NUCLEOTIDE-BINDING
4nct:C (LEU234) to (LEU314) HUMAN DYRK1A IN COMPLEX WITH PKC412 | PROTEIN KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4nct:D (LEU234) to (LEU314) HUMAN DYRK1A IN COMPLEX WITH PKC412 | PROTEIN KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3zmm:B (LEU925) to (GLN1003) INHIBITORS OF JAK2 KINASE DOMAIN | TRANSFERASE
5cf8:A (LEU925) to (GLN1003) CRYSTAL STRUCTURE OF JANUS KINASE 2 IN COMPLEX WITH N,N-DICYCLOPROPYL- 10-ETHYL-7-[(3-METHOXYPROPYL)AMINO] -3-METHYL-3,5,8,10- TETRAAZATRICYCLO[7.3.0.0,6] DODECA-1(9),2(6),4,7,11-PENTAENE-11- CARBOXAMIDE | KINASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5cf8:B (LEU925) to (GLN1003) CRYSTAL STRUCTURE OF JANUS KINASE 2 IN COMPLEX WITH N,N-DICYCLOPROPYL- 10-ETHYL-7-[(3-METHOXYPROPYL)AMINO] -3-METHYL-3,5,8,10- TETRAAZATRICYCLO[7.3.0.0,6] DODECA-1(9),2(6),4,7,11-PENTAENE-11- CARBOXAMIDE | KINASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5csh:A (PRO109) to (PHE181) CRYSTAL STRUCTURE OF CK2ALPHA WITH COMPOUND 4 BOUND | CK2ALPHA, CK2A, FRAGMENT BASED DRUG DISCOVERY, HIGH CONCENTRATION SCREENING, SELECTIVE ATP COMPETITIVE INHIBITORS, SURFACE ENTROPHY REDUCTION, TRANSFERASE
2o5k:A (LYS123) to (GLN206) CRYSTAL STRUCTURE OF GSK3BETA IN COMPLEX WITH A BENZOIMIDAZOL INHIBITOR | GSK3BETA, BENZOIMIDAZOL INHIBITOR, TRANSFERASE
1m2r:A (PRO109) to (PHE181) CRYSTAL STRUCTURE OF 5,8-DI-AMINO-1,4-DI-HYDROXY- ANTHRAQUINONE/CK2 KINASE COMPLEX | KINASE, INHIBITOR-ENZYME COMPLEX, TRANSFERASE
5cu6:A (PRO109) to (PHE181) CRYSTAL STRUCTURE OF CK2ALPHA | CK2ALPHA, CK2A, FRAGMENT BASED DRUG DISCOVERY, HIGH CONCENTRATION SCREENING, SELECTIVE ATP COMPETITIVE INHIBITORS, SURFACE ENTROPHY REDUCTION, TRANSFERASE
4acd:A (ASP124) to (GLN206) GSK3B IN COMPLEX WITH INHIBITOR | TRANSFERASE
4acd:B (GLU125) to (GLN206) GSK3B IN COMPLEX WITH INHIBITOR | TRANSFERASE
3kl8:A (PHE84) to (VAL163) CAMKIINTIDE INHIBITOR COMPLEX | CAMKII, CAMKIINTIDE, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, CELL JUNCTION, CELL MEMBRANE, MEMBRANE, POSTSYNAPTIC CELL MEMBRANE, PROTEIN KINASE INHIBITOR, SYNAPSE, SYNAPTOSOME, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
1y57:A (ILE334) to (ILE411) STRUCTURE OF UNPHOSPHORYLATED C-SRC IN COMPLEX WITH AN INHIBITOR | KINASE STRUCTURE, SH3, SH2, TRANSFERASE
4agu:A (LEU76) to (LEU151) CRYSTAL STRUCTURE OF THE HUMAN CDKL1 KINASE DOMAIN | TRANSFERASE, PHOSPHO-MIMETIC, KINASE
4agu:B (LEU76) to (LEU151) CRYSTAL STRUCTURE OF THE HUMAN CDKL1 KINASE DOMAIN | TRANSFERASE, PHOSPHO-MIMETIC, KINASE
4agu:C (LEU76) to (LEU151) CRYSTAL STRUCTURE OF THE HUMAN CDKL1 KINASE DOMAIN | TRANSFERASE, PHOSPHO-MIMETIC, KINASE
1mru:A (GLY85) to (ILE163) INTRACELLULAR SER/THR PROTEIN KINASE DOMAIN OF MYCOBACTERIUM TUBERCULOSIS PKNB. | REGULATORY, ATP-RECOGNITION, MOLECULAR EVOLUTION, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, TRANSFERASE
1mru:B (GLY85) to (ILE163) INTRACELLULAR SER/THR PROTEIN KINASE DOMAIN OF MYCOBACTERIUM TUBERCULOSIS PKNB. | REGULATORY, ATP-RECOGNITION, MOLECULAR EVOLUTION, STRUCTURAL GENOMICS, PSI, PROTEIN STRUCTURE INITIATIVE, TB STRUCTURAL GENOMICS CONSORTIUM, TBSGC, TRANSFERASE
3krw:A (LEU267) to (SER343) HUMAN GRK2 IN COMPLEX WITH GBETGAMMA SUBUNITS AND BALANOL (SOAK) | PROTEIN KINASE, INHIBITOR, COMPLEX, WD40, PH DOMAIN, RGS HOMOLOGY DOMAIN, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, POLYMORPHISM, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, ACETYLATION, TRANSDUCER, WD REPEAT, CELL MEMBRANE, LIPOPROTEIN, MEMBRANE, METHYLATION, PRENYLATION, PROTEIN BINDING
3krx:A (LEU267) to (SER343) HUMAN GRK2 IN COMPLEX WITH GBETGAMMA SUBUNITS AND BALANOL (CO-CRYSTAL) | RGS HOMOLOGY DOMAIN, ATP-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE- PROTEIN KINASE, TRANSFERASE, TRANSDUCER, WD REPEAT, CELL MEMBRANE, LIPOPROTEIN, MEMBRANE, METHYLATION, PRENYLATION, PROTEIN BINDING
1yhv:A (LEU340) to (THR415) CRYSTAL STRUCTURE OF PAK1 KINASE DOMAIN WITH TWO POINT MUTATIONS (K299R, T423E) | KINASE; ACTIVE CONFORMATION; ACTIVATION LOOP; ATP BINDING SITE, SIGNALING PROTEIN, TRANSFERASE
3kvw:A (ILE224) to (GLU302) CRYSTAL STRUCTURE OF DUAL-SPECIFICITY TYROSINE PHOSPHORYLATION REGULATED KINASE 2 (DYRK2) IN COMPLEX WITH AN INDIRUBIN LIGAND | DYRK2, DUAL-SPECIFICITY TYROSINE, KI-(Y)-PHOSPHORYLATION REGULATED KINASE 2, PSK-H2, KINASE, STRUCTURAL GENOMICS CONSORTIUM, SGC, APOPTOSIS, ATP-BINDING, NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, TYROSINE-PROTEIN KINASE
1ym7:A (LEU267) to (SER343) G PROTEIN-COUPLED RECEPTOR KINASE 2 (GRK2) | G PROTEIN, KINASE, GPCR, GRK2, BETA-ARK1, TRANSFERASE
1ym7:B (LEU267) to (SER343) G PROTEIN-COUPLED RECEPTOR KINASE 2 (GRK2) | G PROTEIN, KINASE, GPCR, GRK2, BETA-ARK1, TRANSFERASE
1ym7:C (LEU267) to (SER343) G PROTEIN-COUPLED RECEPTOR KINASE 2 (GRK2) | G PROTEIN, KINASE, GPCR, GRK2, BETA-ARK1, TRANSFERASE
1ym7:D (LEU267) to (SER343) G PROTEIN-COUPLED RECEPTOR KINASE 2 (GRK2) | G PROTEIN, KINASE, GPCR, GRK2, BETA-ARK1, TRANSFERASE
3lcb:B (HIS412) to (MET482) THE CRYSTAL STRUCTURE OF ISOCITRATE DEHYDROGENASE KINASE/PHOSPHATASE IN COMPLEX WITH ITS SUBSTRATE, ISOCITRATE DEHYDROGENASE, FROM ESCHERICHIA COLI. | KINASE PHOSPHATASE, GLYOXYLATE BYPASS, HYDROLASEPROTEIN PHOSPHATASE, TRICARBOXYLIC ACID CYCLE, ISOCITRATE, TRANSFERASE, HYDROLASE
4pte:A (GLU125) to (GLN206) STRUCTURE OF A CARVOXAMIDE COMPOUND (15) (N-[4-(ISOQUINOLIN-7-YL) PYRIDIN-2-YL]CYCLOPROPANECARBOXAMIDE) TO GSK3B | SERINE/THREONINE KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4pte:B (GLU125) to (GLN206) STRUCTURE OF A CARVOXAMIDE COMPOUND (15) (N-[4-(ISOQUINOLIN-7-YL) PYRIDIN-2-YL]CYCLOPROPANECARBOXAMIDE) TO GSK3B | SERINE/THREONINE KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3at3:A (PRO109) to (PHE181) CRYSTAL STRUCTURE OF CK2ALPHA WITH PYRADINE DERIVATIVE | CK2, KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4aze:A (LEU234) to (GLN313) HUMAN DYRK1A IN COMPLEX WITH LEUCETTINE L41 | TRANSFERASE
4aze:B (LEU234) to (GLN313) HUMAN DYRK1A IN COMPLEX WITH LEUCETTINE L41 | TRANSFERASE
4aze:C (LEU234) to (GLN313) HUMAN DYRK1A IN COMPLEX WITH LEUCETTINE L41 | TRANSFERASE
3m1s:A (GLU125) to (GLN206) STRUCTURE OF RUTHENIUM HALF-SANDWICH COMPLEX BOUND TO GLYCOGEN SYNTHASE KINASE 3 | TRANSFERASE, ENZYME INHIBITOR, ORGANOMETALLIC COMPOUND, RUTHENIUM CENTER, RUTHENIUM PYRIDOCARBAZOLE, ATP-BINDING, KINASE, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, WNT SIGNALING PATHWAY, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3m1s:B (GLU125) to (GLN206) STRUCTURE OF RUTHENIUM HALF-SANDWICH COMPLEX BOUND TO GLYCOGEN SYNTHASE KINASE 3 | TRANSFERASE, ENZYME INHIBITOR, ORGANOMETALLIC COMPOUND, RUTHENIUM CENTER, RUTHENIUM PYRIDOCARBAZOLE, ATP-BINDING, KINASE, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, WNT SIGNALING PATHWAY, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5ebz:A (PRO91) to (VAL172) HUMAN KINASE | KINASE, INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5ebz:B (PRO91) to (VAL172) HUMAN KINASE | KINASE, INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5ebz:D (PRO91) to (VAL172) HUMAN KINASE | KINASE, INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5ebz:E (PRO91) to (VAL172) HUMAN KINASE | KINASE, INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5ebz:J (PRO91) to (VAL172) HUMAN KINASE | KINASE, INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4qfs:A (ILE89) to (ASP166) STRUCTURE OF AMPK IN COMPLEX WITH BR2-A769662CORE ACTIVATOR AND STAUROSPORINE INHIBITOR | CBM, KINASE, AMPK, SIGNALING PROTEIN-INHIBITOR-ACTIVATOR COMPLEX
4b8m:B (ILE166) to (PRO242) AURORA B KINASE IN COMPLEX WITH VX-680 | CELL CYCLE, CANCER
4qmx:A (LEU95) to (THR170) MST3 IN COMPLEX WITH SARACATINIB | PROTEIN KINASE, MST3, STK24, STERILE 20-LIKE KINASE, ATP-BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3mfu:A (LEU87) to (GLU171) CASK-4M CAM KINASE DOMAIN, AMPPNP-MN2+ | CATALYTIC MECHANISM, KINASE CATALYSIS, MG2+-MEDIATED PHOSPHATE TRANSFER, PROTEIN KINASE, TRANSFERASE
4qpa:A (LYS97) to (VAL171) CRYSTAL STRUCTURE OF ERK2 IN COMPLEX WITH 7-(1-BENZYL-1H-PYRAZOL-4- YL)-2-(PYRIDIN-4-YL)-5H-PYRROLO[2,3-B]PYRAZINE | KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4qps:A (LEU898) to (LEU976) CRYSTAL STRUCTURE OF JAK3 COMPLEXED TO N-[3-(6-PHENYLAMINO-PYRAZIN-2- YL)-3H-BENZOIMIDAZOL-5-YL]-ACRYLAMIDE | KINASE CATALYTIC DOMAIN, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4bid:A (ILE750) to (ARG828) CRYSTAL STRUCTURES OF ASK1-INHIBITOR COMPLEXES | TRANSFERASE
4qt1:A (LEU898) to (LEU976) JAK3 KINASE DOMAIN IN COMPLEX WITH 1-[(3S)-1-ISOBUTYLSULFONYL-3- PIPERIDYL]-3-(5H-PYRROLO[2,3-B]PYRAZIN-2-YL)UREA | KINASE-INHIBITOR COMPLEX, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3bkb:A (ILE632) to (GLU708) CRYSTAL STRUCTURE OF HUMAN FELINE SARCOMA VIRAL ONCOGENE HOMOLOGUE (V- FES) | FES, V-FES, FUJINAMI, AVIAN SARCOMA, VIRAL, ONCOGENE, FELINE SARCOMA VIRUS, SGC, STRUCTURAL GENOMICS CONSORTIUM, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, PROTO-ONCOGENE, SH2 DOMAIN, TRANSFERASE, TYROSINE-PROTEIN KINASE
3mtl:A (LEU236) to (ALA310) CRYSTAL STRUCTURE OF THE PCTAIRE1 KINASE IN COMPLEX WITH INDIRUBIN E804 | PCTAIRE1, KINASE, INDIRUBIN, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE
5ezv:A (GLU94) to (ASP166) X-RAY CRYSTAL STRUCTURE OF AMP-ACTIVATED PROTEIN KINASE ALPHA-2/ALPHA- 1 RIM CHIMAERA (ALPHA-2(1-347)/ALPHA-1(349-401)/ALPHA-2(397-END) BETA-1 GAMMA-1) CO-CRYSTALLIZED WITH C2 (5-(5-HYDROXYL-ISOXAZOL-3- YL)-FURAN-2-PHOSPHONIC ACID) | TRANSFERASE, SERINE/THREONINE KINASE, ALLOSTERIC ACTIVATION, NUCLEOTIDE-BINDING
5ezv:C (PHE89) to (ASP166) X-RAY CRYSTAL STRUCTURE OF AMP-ACTIVATED PROTEIN KINASE ALPHA-2/ALPHA- 1 RIM CHIMAERA (ALPHA-2(1-347)/ALPHA-1(349-401)/ALPHA-2(397-END) BETA-1 GAMMA-1) CO-CRYSTALLIZED WITH C2 (5-(5-HYDROXYL-ISOXAZOL-3- YL)-FURAN-2-PHOSPHONIC ACID) | TRANSFERASE, SERINE/THREONINE KINASE, ALLOSTERIC ACTIVATION, NUCLEOTIDE-BINDING
3c0i:A (LEU87) to (GLU171) CASK CAM-KINASE DOMAIN- 3'-AMP COMPLEX, P212121 FORM | CASK, NEUREXIN, CA2+/CALMODULIN DEPENDENT PROTEIN KINASE, MG2+, SYNAPTIC PLASTICITY, PSEUDOKINASE, MAGUK, MEMBRANE-ASSOCIATED GUANYLATE KINASE, ATP-BINDING, CALMODULIN-BINDING, MAGNESIUM, METAL- BINDING, NUCLEOTIDE-BINDING, NUCLEUS, SERINE/THREONINE-PROTEIN KINASE, SH3 DOMAIN, TRANSFERASE
3n9x:A (GLU110) to (ILE179) CRYSTAL STRUCTURE OF MAP KINASE FROM PLASMODIUM BERGHEI, PB000659.00.0 | MALARIA KINASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE
3n9x:B (ASP103) to (ILE179) CRYSTAL STRUCTURE OF MAP KINASE FROM PLASMODIUM BERGHEI, PB000659.00.0 | MALARIA KINASE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, TRANSFERASE
3cbl:A (ILE632) to (ALA709) CRYSTAL STRUCTURE OF HUMAN FELINE SARCOMA VIRAL ONCOGENE HOMOLOGUE (V- FES) IN COMPLEX WITH STAUROSPORINE AND A CONSENSUS PEPTIDE | FES, V-FES, FUJINAMI, AVIAN SARCOMA, VIRAL, ONCOGENE, FELINE SARCOMA VIRUS, SGC, STRUCTURAL GENOMICS CONSORTIUM, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, PROTO-ONCOGENE, SH2 DOMAIN, TRANSFERASE, TYROSINE-PROTEIN KINASE
3cd3:A (ILE632) to (GLU708) CRYSTAL STRUCTURE OF PHOSPHORYLATED HUMAN FELINE SARCOMA VIRAL ONCOGENE HOMOLOGUE (V-FES) IN COMPLEX WITH STAUROSPORINE AND A CONSENSUS PEPTIDE | FES, V-FES, FUJINAMI, AVIAN SARCOMA, VIRAL, ONCOGENE, FELINE SARCOMA VIRUS, ACTIVE, SGC, STRUCTURAL GENOMICS CONSORTIUM, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, PROTO-ONCOGENE, SH2 DOMAIN, TRANSFERASE, TYROSINE-PROTEIN KINASE
4c2v:B (ILE166) to (PRO242) AURORA B KINASE IN COMPLEX WITH THE SPECIFIC INHIBITOR BARASERTIB | TRANSFERASE-CELL CYCLE COMPLEX, AZD1152
4c2w:B (GLU171) to (PRO242) CRYSTAL STRUCTURE OF AURORA B IN COMPLEX WITH AMP-PNP | TRANSFERASE
3nie:A (GLU112) to (ILE181) CRYSTAL STRUCTURE OF PF11_0147 | MALARIA, MAPK, KINASE, SGC, STRUCTURAL GENOMICS CONSORTIUM, STRUCTURAL GENOMICS, TRANSFERASE
3nie:B (ASP105) to (ILE181) CRYSTAL STRUCTURE OF PF11_0147 | MALARIA, MAPK, KINASE, SGC, STRUCTURAL GENOMICS CONSORTIUM, STRUCTURAL GENOMICS, TRANSFERASE
4c61:B (LEU925) to (GLN1003) INHIBITORS OF JAK2 KINASE DOMAIN | KINASE, TRANSFERASE
4c62:B (LEU925) to (GLN1003) INHIBITORS OF JAK2 KINASE DOMAIN | TRANSFERASE
4cfe:A (PHE89) to (ASP166) STRUCTURE OF FULL LENGTH HUMAN AMPK IN COMPLEX WITH A SMALL MOLECULE ACTIVATOR, A BENZIMIDAZOLE DERIVATIVE (991) | TRANSFERASE, NUCLEOTIDE-BINDING, STAUROSPORINE-BINDING, SERINE/THREONINE-PROTEIN KINASE, ACTIVATOR, CARBOHYDRATE BINDING MODULE (CBM)
4cfe:C (ASP88) to (ASP166) STRUCTURE OF FULL LENGTH HUMAN AMPK IN COMPLEX WITH A SMALL MOLECULE ACTIVATOR, A BENZIMIDAZOLE DERIVATIVE (991) | TRANSFERASE, NUCLEOTIDE-BINDING, STAUROSPORINE-BINDING, SERINE/THREONINE-PROTEIN KINASE, ACTIVATOR, CARBOHYDRATE BINDING MODULE (CBM)
3d14:A (VAL219) to (HIS293) CRYSTAL STRUCTURE OF MOUSE AURORA A (ASN186->GLY, LYS240->ARG, MET302- >LEU) IN COMPLEX WITH 1-{5-[2-(THIENO[3,2-D]PYRIMIDIN-4-YLAMINO)- ETHYL]- THIAZOL-2-YL}-3-(3-TRIFLUOROMETHYL-PHENYL)-UREA | AURORA A, SMALL-MOLECULE INHIBITOR, KINASE, TRANSFERASE
5g1x:A (VAL206) to (PRO282) CRYSTAL STRUCTURE OF AURORA-A KINASE IN COMPLEX WITH N-MYC | TRANSFERASE, AURORA, AURORA-A, KINASE, N-MYC, MYC, NEUROBLASTOMA
4tnb:A (LEU259) to (PRO337) CRYSTAL STRUCTURE OF G PROTEIN-COUPLED RECEPTOR KINASE 5 IN COMPLEX WITH SANGIVAMYCIN | GRK5-SANGIVAMYCIN COMPLEX, GPCR KINASE, KINASE, INHIBITOR, SIGNALING PROTEIN
3db6:A (GLU117) to (GLU188) CRYSTAL STRUCTURE OF AN ACTIVATED (THR->ASP) POLO-LIKE KINASE 1 (PLK1) CATALYTIC DOMAIN IN COMPLEX WITH COMPOUND 902 | POLO-LIKE KINASE 1, PLK1, CATALYTIC DOMAIN, SMALL-MOLECULE INHIBITOR, KINASE, TRANSFERASE
3db8:A (GLU117) to (ILE187) CRYSTAL STRUCTURE OF AN ACTIVATED (THR->ASP) POLO-LIKE KINASE 1 (PLK1) CATALYTIC DOMAIN IN COMPLEX WITH COMPOUND 041 | POLO-LIKE KINASE 1, PLK1, CATALYTIC DOMAIN, SMALL-MOLECULE INHIBITOR, KINASE, TRANSFERASE
3dbc:A (GLU117) to (ILE187) CRYSTAL STRUCTURE OF AN ACTIVATED (THR->ASP) POLO-LIKE KINASE 1 (PLK1) CATALYTIC DOMAIN IN COMPLEX WITH COMPOUND 257 | POLO-LIKE KINASE 1, PLK1, CATALYTIC DOMAIN, SMALL-MOLECULE INHIBITOR, KINASE, TRANSFERASE
3dbd:A (GLU117) to (ILE187) CRYSTAL STRUCTURE OF AN ACTIVATED (THR->ASP) POLO-LIKE KINASE 1 (PLK1) CATALYTIC DOMAIN IN COMPLEX WITH COMPOUND 094 | POLO-LIKE KINASE 1, PLK1, CATALYTIC DOMAIN, SMALL-MOLECULE INHIBITOR, KINASE, TRANSFERASE
4tpt:B (LEU401) to (VAL477) CRYSTAL STRUCTURE OF THE HUMAN LIMK2 KINASE DOMAIN IN COMPLEX WITH A NON-ATP COMPETITIVE INHIBITOR | LIMK2 KINASE, DFG INHIBITOR
3dls:B (PHE1077) to (ARG1155) CRYSTAL STRUCTURE OF HUMAN PAS KINASE BOUND TO ADP | PAS KINASE, PASK, PROTEIN KINASE, DRUG DISCOVERY, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
3dls:C (PHE1077) to (LEU1153) CRYSTAL STRUCTURE OF HUMAN PAS KINASE BOUND TO ADP | PAS KINASE, PASK, PROTEIN KINASE, DRUG DISCOVERY, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
3dls:D (PHE1077) to (LEU1153) CRYSTAL STRUCTURE OF HUMAN PAS KINASE BOUND TO ADP | PAS KINASE, PASK, PROTEIN KINASE, DRUG DISCOVERY, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
3dls:F (PHE1077) to (LEU1153) CRYSTAL STRUCTURE OF HUMAN PAS KINASE BOUND TO ADP | PAS KINASE, PASK, PROTEIN KINASE, DRUG DISCOVERY, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSFERASE, STRUCTURAL GENOMICS, PSI-2, PROTEIN STRUCTURE INITIATIVE, NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS, NYSGXRC
3du8:A (LEU128) to (GLN206) CRYSTAL STRUCTURE OF GSK-3 BETA IN COMPLEX WITH NMS-869553A | PROTEIN KINASE, ALTERNATIVE SPLICING, ATP-BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE- PROTEIN KINASE, TRANSFERASE
3owj:A (PRO109) to (PHE181) HUMAN CK2 CATALYTIC DOMAIN IN COMPLEX WITH A PYRIDOCARBAZOLE DERIVATIVE INHIBITOR | SERINE/THREONINE-PROTEIN KINASE, CK2, INHIBITOR, PYRIDOCARBAZOLE, ELLIPTICINE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5hgi:A (PHE637) to (LEU718) CRYSTAL STRUCTURE OF APO HUMAN IRE1 ALPHA | SER/THR PROTEIN KINASE, RNASE, TRANSFERASE-OXIDOREDUCTASE COMPLEX
4dit:A (GLU125) to (GLN206) CRYSTAL STRUCTURE OF GSK3BETA IN COMPLEX WITH A IMIDAZOPYRIDINE INHIBITOR | KINASE, Y216 PHOSPHORYLATION, PHOSPHOTRANSFERASE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
5hlp:B (GLU125) to (GLN206) X-RAY CRYSTAL STRUCTURE OF GSK3B IN COMPLEX WITH BRD3937 | PROTEIN KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3p9j:A (GLU211) to (VAL279) AURORA A KINASE DOMAIN WITH PHTHALAZINONE PYRAZOLE INHIBITOR | PHOSPHOTRANSFERASE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3e3p:A (ARG92) to (LYS176) GLYCOGEN SYNTHASE KINASE FROM LEISHMANIA MAJOR | GLYCOGEN SYNTHASE KINASE, LEISHMANIASIS, KINASE, TRANSFERASE
5hx8:B (GLY951) to (THR1030) JAK1 COMPLEX WITH 4-[(4-AMINOCYCLOHEXYL)AMINO]-3-(1H-BENZIMIDAZOL-2- YL)-1H-PYRIDIN-2-ONE | KINASE, INHIBITOR, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4e4l:A (GLY951) to (THR1030) JAK1 KINASE (JH1 DOMAIN) IN COMPLEX WITH COMPOUND 30 | O-PHOSPHOTYROSINE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4e4l:E (GLY951) to (THR1030) JAK1 KINASE (JH1 DOMAIN) IN COMPLEX WITH COMPOUND 30 | O-PHOSPHOTYROSINE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4e4l:D (ILE952) to (THR1030) JAK1 KINASE (JH1 DOMAIN) IN COMPLEX WITH COMPOUND 30 | O-PHOSPHOTYROSINE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4e4m:B (LEU925) to (GLN1003) JAK2 KINASE (JH1 DOMAIN) IN COMPLEX WITH COMPOUND 30 | O-PHOSPHOTYROSINE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4e4n:B (GLY951) to (THR1030) JAK1 KINASE (JH1 DOMAIN) IN COMPLEX WITH COMPOUND 49 | O-PHOSPHOTYROSINE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4e7w:A (ASP105) to (ILE187) STRUCTURE OF GSK3 FROM USTILAGO MAYDIS | GSK3, KINASE, PTYR195, TRANSFERASE
4e93:A (ILE632) to (GLU707) CRYSTAL STRUCTURE OF HUMAN FELINE SARCOMA VIRAL ONCOGENE HOMOLOGUE (V- FES)IN COMPLEX WITH TAE684 | V-FES, FUJINAMI, AVIAN SARCOMA, VIRAL, ONCOGENE, FELINE SARCOMA VIRUS, ATP-BINDING, KINASE, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, PROTO-ONCOGENE, SH2 DOMAIN, TRANSFERASE, TYROSINE-PROTEIN KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3psc:A (LEU267) to (SER343) BOVINE GRK2 IN COMPLEX WITH GBETAGAMMA SUBUNITS | KINASE, SERINE/THREONINE-PROTEIN KINASE, ATP-BINDING, MEMBRANE, TRANSFERASE-SIGNALING PROTEIN COMPLEX
4ehz:B (GLY951) to (THR1030) THE JAK1 KINASE DOMAIN IN COMPLEX WITH INHIBITOR | KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ehz:C (GLY951) to (THR1030) THE JAK1 KINASE DOMAIN IN COMPLEX WITH INHIBITOR | KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ehz:D (GLY951) to (THR1030) THE JAK1 KINASE DOMAIN IN COMPLEX WITH INHIBITOR | KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ei4:A (GLY951) to (THR1030) JAK1 KINASE (JH1 DOMAIN) IN COMPLEX WITH COMPOUND 20 | PROTEIN KINASE, PHOSPHO-TRANSFER CATALYST, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ei4:B (GLY951) to (THR1030) JAK1 KINASE (JH1 DOMAIN) IN COMPLEX WITH COMPOUND 20 | PROTEIN KINASE, PHOSPHO-TRANSFER CATALYST, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4ux9:C (GLN102) to (ALA176) CRYSTAL STRUCTURE OF JNK1 BOUND TO A MKK7 DOCKING MOTIF | TRANSFERASE, JNK1, INTRINSICALLY DISORDERED DOMAINS, MKK7
4fif:A (MET395) to (SER466) CATALYTIC DOMAIN OF HUMAN PAK4 WITH RPKPLVDP PEPTIDE | SERINE/THREONINE-PROTEIN KINASE PAK4, KINASE DOMAIN, PROTEIN KINASE, ATP BINDING, PHOSPHORYLATION, TRANSFERASE-PEPTIDE COMPLEX
4fih:A (MET395) to (SER466) CATALYTIC DOMAIN OF HUMAN PAK4 WITH QKFTGLPRQW PEPTIDE | SERINE/THREONINE-PROTEIN KINASE PAK4, KINASE DOMAIN, PROTEIN KINASE, ATP BINDING, PHOSPHORYLATION, TRANSFERASE
4fii:A (MET395) to (SER466) CATALYTIC DOMAIN OF HUMAN PAK4 WITH RPKPLVDP PEPTIDE | SERINE/THREONINE-PROTEIN KINASE PAK4, KINASE DOMAIN, PROTEIN KINASE, ATP BINDING, PHOSPHORYLATION, TRANSFERASE-PEPTIDE COMPLEX
4fij:A (MET395) to (SER466) CATALYTIC DOMAIN OF HUMAN PAK4 | SERINE/THREONINE-PROTEIN KINASE PAK4, KINASE DOMAIN, PROTEIN KINASE, ATP BINDING, PHOSPHORYLATION, TRANSFERASE
4g3g:A (TRP466) to (LEU543) CRYSTAL STRUCTURE OF MURINE NF-KAPPAB INDUCING KINASE (NIK) V408L BOUND TO A 2-(AMINOTHIAZOLYL)PHENOL (CMP3) | NON-RD KINASE, PROTEIN SERINE/THREONINE KINASE, NF-KAPPAB, MAP3K14, STRUCTURE-BASED DRUG DESIGN, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5kq5:A (ILE89) to (ASP166) AMPK BOUND TO ALLOSTERIC ACTIVATOR | KINASE ALLOSTERIC ACTIVATOR, TRANSFERASE
5kx8:A (LEU258) to (SER336) IRAK4-INHIBITOR CO-STRUCTURE | KINASE, PHOSPHATASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5lxc:A (ILE224) to (TYR301) CRYSTAL STRUCTURE OF DYRK2 IN COMPLEX WITH EHT 5372 (COMPOUND 1) | TRANSFERASE, KINASE, INHIBITOR, UNUSUAL BINDING MODE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC
5lxc:B (ILE224) to (TYR301) CRYSTAL STRUCTURE OF DYRK2 IN COMPLEX WITH EHT 5372 (COMPOUND 1) | TRANSFERASE, KINASE, INHIBITOR, UNUSUAL BINDING MODE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC
5tf9:B (GLU302) to (LEU374) CRYSTAL STRUCTURE OF WNK1 IN COMPLEX WITH MN2+AMPPNP AND WNK476 | SERINE-THREONINE-PROTEIN KINASE, INHIBITOR, TERNARY, COMPLEX, ALLOSTERIC, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2bcj:A (LEU267) to (SER343) CRYSTAL STRUCTURE OF G PROTEIN-COUPLED RECEPTOR KINASE 2 IN COMPLEX WITH GALPHA-Q AND GBETAGAMMA SUBUNITS | PERIPHERAL MEMBRANE COMPLEX, PROTEIN KINASE, RGS DOMAIN, WD40 PROTEIN, HETEROTRIMERIC G PROTEIN, TRANSFERASE-HYDROLASE COMPLEX
3sd0:A (ASP124) to (GLN206) IDENTIFICATION OF A GLYCOGEN SYNTHASE KINASE-3B INHIBITOR THAT ATTENUATES HYPERACTIVITY IN CLOCK MUTANT MICE | KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3sd0:B (GLU125) to (GLN206) IDENTIFICATION OF A GLYCOGEN SYNTHASE KINASE-3B INHIBITOR THAT ATTENUATES HYPERACTIVITY IN CLOCK MUTANT MICE | KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2pvr:A (PRO109) to (PHE181) CRYSTAL STRUCTURE OF THE CATALYTIC SUBUNIT OF PROTEIN KINASE CK2 (C- TERMINAL DELETION MUTANT 1-335) IN COMPLEX WITH TWO SULFATE IONS | EUKARYOTIC PROTEIN KINASE FOLD, CMGC KINASES, SIGNALING PROTEIN, TRANSFERASE
4xs2:C (LEU258) to (SER336) IRAK4-INHIBITOR CO-STRUCTURE | KINASE, PHOSPHATASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1ds5:A (PRO109) to (PHE181) DIMERIC CRYSTAL STRUCTURE OF THE ALPHA SUBUNIT IN COMPLEX WITH TWO BETA PEPTIDES MIMICKING THE ARCHITECTURE OF THE TETRAMERIC PROTEIN KINASE CK2 HOLOENZYME. | PROTEIN-COMPLEX, TETRAMER, TRANSFERASE
4ivc:B (GLY951) to (THR1030) JAK1 KINASE (JH1 DOMAIN) IN COMPLEX WITH THE INHIBITOR (TRANS-4-{2- [(1R)-1-HYDROXYETHYL]IMIDAZO[4,5-D]PYRROLO[2,3-B]PYRIDIN-1(6H)- YL}CYCLOHEXYL)ACETONITRILE | PROTEIN KINASE, PHOSPHO TRANSFER, PHOSPHO TYROSINE, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
1q97:A (GLY239) to (TRP556) THE STRUCTURE OF THE SACCHAROMYCES CEREVISIAE SR PROTEIN KINASE, SKY1P, WITH BOUND ATP | PROTEIN KINASE, TRANSFERASE
1q97:B (GLY239) to (TRP556) THE STRUCTURE OF THE SACCHAROMYCES CEREVISIAE SR PROTEIN KINASE, SKY1P, WITH BOUND ATP | PROTEIN KINASE, TRANSFERASE
2vgp:B (ILE166) to (PRO242) CRYSTAL STRUCTURE OF AURORA B KINASE IN COMPLEX WITH A AMINOTHIAZOLE INHIBITOR | NUCLEOTIDE-BINDING, SERINE/THREONINE-PROTEIN KINASE, ATP-BINDING, TRANSFERASE, COILED COIL, CELL DIVISION, KINASE, CANCER, INCENP, NUCLEUS, MITOSIS, AURORA B, METAL-BINDING, AMINOTHIAZOLE, PHOSPHORYLATION, MAGNESIUM, CELL CYCLE, CENTROMERE, MICROTUBULE
2vx3:A (LEU234) to (GLN313) CRYSTAL STRUCTURE OF THE HUMAN DUAL SPECIFICITY TYROSINE- PHOSPHORYLATION-REGULATED KINASE 1A | SERINE/THREONINE-PROTEIN KINASE, MINIBRAIN HOMOLOG, NUCLEOTIDE-BINDING, TRANSFERASE, PHOSPHOPROTEIN, TYROSINE-PROTEIN KINASE, CASP8, KINASE
2vx3:B (LEU234) to (GLN313) CRYSTAL STRUCTURE OF THE HUMAN DUAL SPECIFICITY TYROSINE- PHOSPHORYLATION-REGULATED KINASE 1A | SERINE/THREONINE-PROTEIN KINASE, MINIBRAIN HOMOLOG, NUCLEOTIDE-BINDING, TRANSFERASE, PHOSPHOPROTEIN, TYROSINE-PROTEIN KINASE, CASP8, KINASE
2vx3:D (LEU234) to (GLN313) CRYSTAL STRUCTURE OF THE HUMAN DUAL SPECIFICITY TYROSINE- PHOSPHORYLATION-REGULATED KINASE 1A | SERINE/THREONINE-PROTEIN KINASE, MINIBRAIN HOMOLOG, NUCLEOTIDE-BINDING, TRANSFERASE, PHOSPHOPROTEIN, TYROSINE-PROTEIN KINASE, CASP8, KINASE
1h8f:A (GLU125) to (GLN206) GLYCOGEN SYNTHASE KINASE 3 BETA. | KINASE, INSULIN PATHWAY
1h8f:B (GLU125) to (GLN206) GLYCOGEN SYNTHASE KINASE 3 BETA. | KINASE, INSULIN PATHWAY
2wo6:A (LEU234) to (GLN313) HUMAN DUAL-SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 1A IN COMPLEX WITH A CONSENSUS SUBSTRATE PEPTIDE | TRANSFERASE-PEPTIDE COMPLEX, TRANSFERASE PEPTIDE COMPLEX, SERINE/THREONINE-PROTEIN ATP-BINDING, PHOSPHOPROTEIN, NUCLEOTIDE-BINDING, DYRK1, DYRK1A, KINASE, NUCLEUS, TRANSFERASE, TYROSINE-PROTEIN KINASE
5a4l:D (LEU234) to (GLN313) DYRK1A IN COMPLEX WITH FLUORO BENZOTHIAZOLE FRAGMENT | TRANSFERASE
2x3k:A (GLY365) to (ASP473) CO-COMPLEX STRUCTURE OF ACHROMOBACTIN SYNTHETASE PROTEIN D ( ACSD) WITH AMP AND SULFATE FROM PECTOBACTERIUM CHRYSANTHEMI | ALCALIGIN BIOSYNTHESIS, LIGASE, ALCC, ADENYLATION, SIDEROPHORES, IRON ACQUISITION
3zep:B (LEU898) to (LEU976) CRYSTAL STRUCTURE OF JAK3 KINASE DOMAIN IN COMPLEX WITH A PYRROLOPYRAZINE-2-PHENYL ETHER INHIBITOR | TRANSFERASE, STAT5, STAT6, INTERLEUKIN-2, COMMON-GAMMA CHAIN, ATP SITE KINASE INHIBITOR, CANCER, SCID, SEVERE COMBINED IMMUNODEFICIENCY
5byz:A (LYS131) to (LEU207) ERK5 IN COMPLEX WITH SMALL MOLECULE | ERK5, KINASE INHIBITOR, TRANSFERASE
4o0v:A (LEU391) to (SER466) BACK POCKET FLEXIBILITY PROVIDES GROUP-II PAK SELECTIVITY FOR TYPE 1 KINASE INHIBITORS | PAK4, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4pds:B (TYR269) to (VAL345) CRYSTAL STRUCTURE OF RAD53 KINASE DOMAIN AND SCD2 IN COMPLEX WITH AMPPNP | KINASE DOMAIN, ANP, C-LOBE, ACTIVATION SEGMENT EXCHANGE, TRANSFERASE
3lj2:B (GLU746) to (LEU835) IRE1 COMPLEXED WITH JAK INHIBITOR I | KINASE, KINASE INHIBITOR, NUCLEASE ACTIVATOR, ATP-BINDING, ENDOPLASMIC RETICULUM, GLYCOPROTEIN, HYDROLASE, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-PROTEIN KINASE, TRANSCRIPTION, TRANSCRIPTION REGULATION, TRANSFERASE, TRANSMEMBRANE, UNFOLDED PROTEIN RESPONSE
3at2:A (PRO109) to (PHE181) CRYSTAL STRUCTURE OF CK2ALPHA | CK2, KINASE, TRANSFERASE
3at4:A (PRO109) to (PHE181) CRYSTAL STRUCTURE OF CK2ALPHA WITH PYRADINE DERIVERTIVE | CK2, KINASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4qfr:A (ILE89) to (ASP166) STRUCTURE OF AMPK IN COMPLEX WITH CL-A769662 ACTIVATOR AND STAUROSPORINE INHIBITOR | CBM, AMPK, KINASE, SIGNALING PROTEIN-INHIBITOR-ACTIVATOR COMPLEX
4qms:A (LEU95) to (THR170) MST3 IN COMPLEX WITH DASATINIB | PROTEIN KINASE, MST3, STK24, STERILE 20-LIKE KINASE, ATP-BINDING, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SERINE/THREONINE-TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4rew:A (ILE91) to (ASP168) CRYSTAL STRUCTURE OF THE NON-PHOSPHORYLATED HUMAN ALPHA1 BETA2 GAMMA1 HOLO-AMPK COMPLEX | HUMAN ALPHA1 BETA2 GAMMA1 HOLO-AMPK COMPLEX, SERINE/THREONINE PROTEIN KINASE, AXIN, CAMKKBETA, LKB1, GLYCOGEN, PHOSPHORYLATION, TRANSFERASE
4cff:C (PHE89) to (ASP166) STRUCTURE OF FULL LENGTH HUMAN AMPK IN COMPLEX WITH A SMALL MOLECULE ACTIVATOR, A THIENOPYRIDONE DERIVATIVE (A-769662) | TRANSFERASE, NUCLEOTIDE-BINDING, STAUROSPORINE-BINDING, SERINE/THREONINE-PROTEIN KINASE, ACTIVATOR, CARBOHYDRATE BINDING MODULE (CBM)
4tnd:A (LEU259) to (ILE336) CRYSTAL STRUCTURE OF G PROTEIN-COUPLED RECEPTOR KINASE 5 IN COMPLEX WITH AMP-PNP | GRK5-(5-ADENYLYLIMIDODIPHOSPHATE) COMPLEX, GRK5-(AMP-PNP) COMPLEX, GPCR KINASE, KINASE, GPCR KINASE 5, SIGNALING PROTEIN
3dbf:A (GLU117) to (ILE187) CRYSTAL STRUCTURE OF AN ACTIVATED (THR->ASP) POLO-LIKE KINASE 1 (PLK1) CATALYTIC DOMAIN IN COMPLEX WITH COMPOUND 562 | POLO-LIKE KINASE 1, PLK1, CATALYTIC DOMAIN, SMALL-MOLECULE INHIBITOR, KINASE, TRANSFERASE
4daw:A (LEU340) to (THR415) CRYSTAL STRUCTURE OF PAK1 KINASE DOMAIN WITH THE RUTHENIUM PHTHALIMIDE COMPLEX | SERINE/THREONINE KINASE, PHOSPHORYLATION, ATP-BINDING, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
5he3:A (ASP272) to (SER343) BOVINE GRK2 IN COMPLEX WITH GBETAGAMMA SUBUNITS AND CCG224411 | RGS, KINASE, PH, WD-40, INHIBITOR COMPLEX, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3owk:A (PRO109) to (PHE181) HUMAN CK2 CATALYTIC DOMAIN IN COMPLEX WITH A BENZOPYRIDOINDOLE DERIVATIVE INHIBITOR | SERINE/THREONINE-PROTEIN KINASE, CK2, INHIBITOR, BENZOPYRIDOINDOLE, ELLIPTICINE, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
4uak:A (LEU149) to (LYS224) MRCK BETA IN COMPLEX WITH ADP | MYOTONIC DYSTROPHY KINASE-RELATED CDC42-BINDING KINASE, METASTASIS, CELL INVASION, TRANSFERASE
3q04:A (PRO109) to (PHE181) CRYSTAL STRUCTURE OF THE APO-FORM OF HUMAN CK2 ALPHA AT PH 8.5 | PROTEIN KINASE, APO-FORM, TRANSFERASE
3qfv:A (LEU149) to (LYS224) MRCK BETA IN COMPLEX WITH TPCA-1 | PROTEIN KINASE DOMAIN OF MRCK BETA IN COMPLEX WITH TPCA-1, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3qfv:B (LEU149) to (LYS224) MRCK BETA IN COMPLEX WITH TPCA-1 | PROTEIN KINASE DOMAIN OF MRCK BETA IN COMPLEX WITH TPCA-1, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5k3y:B (GLU171) to (PRO242) CRYSTAL STRUCTURE OF AURORAB/INCENP IN COMPLEX WITH BI 811283 | KINASE, INHIBITOR, TRANSFERASE
5kx7:A (LEU258) to (SER336) IRAK4-INHIBITOR CO-STRUCTURE | KINASE, PHOSPHATASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
5lxd:A (ILE224) to (TYR301) CRYSTAL STRUCTURE OF DYRK2 IN COMPLEX WITH EHT 1610 (COMPOUND 2) | TRANSFERASE, KINASE, INHIBITOR, UNUSUAL BINDING MODE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC
5lxd:B (ILE224) to (TYR301) CRYSTAL STRUCTURE OF DYRK2 IN COMPLEX WITH EHT 1610 (COMPOUND 2) | TRANSFERASE, KINASE, INHIBITOR, UNUSUAL BINDING MODE, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC