4gvm:A (ILE60) to (VAL165) HIV-1 INTEGRASE CATALYTIC CORE DOMAIN A128T MUTANT COMPLEXED WITH ALLOSTERIC INHIBITOR | INTEGRASE, CCD, DDE MOTIF, DIMER INTERFACE, ALLOSTERIC INHIBITOR, DRUG RESISTANCE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
1asu:A (GLN59) to (GLY175) AVIAN SARCOMA VIRUS INTEGRASE CATALYTIC CORE DOMAIN CRYSTALLIZED FROM 2% PEG 400, 2M AMMONIUM SULFATE, HEPES PH 7.5 | DNA INTEGRATION
2b6a:A (GLU438) to (GLY555) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH THR-50 | AIDS, HIV, DRUG DESIGN, REVERSE TRANSCRIPTASE, RT, PROTEIN- INHIBITOR COMPLEX, TRANSFERASE
4h8k:B (LYS3) to (SER140) CRYSTAL STRUCTURE OF LC11-RNASE H1 IN COMPLEX WITH RNA/DNA HYBRID | RNASE H, RIBONUCLEASE H RNA DNA HYBRID, HYDROLASE, RIBONUCLEASE H, HYDROLASE-DNA-RNA COMPLEX
1b92:A (GLY59) to (VAL165) MOBILITY OF AN HIV-1 INTEGRASE ACTIVE SITE LOOP IS CORRELATED WITH CATALYTIC ACTIVITY | DNA INTEGRATION,TRANSFERASE, TRANSFERASE
1b9d:A (ILE60) to (VAL165) MOBILITY OF AN HIV-1 INTEGRASE ACTIVE SITE LOOP IS CORRELATED WITH CATALYTIC ACTIVITY | DNA INTEGRATION, TRANSFERASE
1bis:B (ILE60) to (VAL165) HIV-1 INTEGRASE CORE DOMAIN | DNA INTEGRATION, INTEGRASE, HIV, HYDROLASE, ASPARTYL PROTEASE, ENDONUCLEASE
1biz:A (GLY59) to (VAL165) HIV-1 INTEGRASE CORE DOMAIN | DNA INTEGRATION, INTEGRASE, HIV, HYDROLASE, ASPARTYL PROTEASE, ENDONUCLEASE
1bqm:A (ALA437) to (SER553) HIV-1 RT/HBY 097 | NUCLEOTIDYLTRANSFERASE, AIDS, RNA-DIRECTED DNA POLYMERASE, HIV-1 RT/HBY 097, DRUG-RESISTANT MUTANT
1bqn:A (ALA437) to (SER553) TYR 188 LEU HIV-1 RT/HBY 097 | NUCLEOTIDYLTRANSFERASE, AIDS, RNA-DIRECTED DNA POLYMERASE, HIV-1 RT/HBY 097, DRUG-RESISTANT MUTANT
1c0m:D (GLN59) to (VAL169) CRYSTAL STRUCTURE OF RSV TWO-DOMAIN INTEGRASE | INTEGRASE, ROUS SARCOMA VIRUS, HIV, X-RAY CRYSTALLOGRAPHY, PROTEIN STRUCTURE, TRANSFERASE
3ffi:A (GLU438) to (LEU551) HIV-1 RT WITH PYRIDONE NON-NUCLEOSIDE INHIBITOR | HIV, RT, REVERSE TRANSCRIPTASE, TRANSFERASE RNA-DIRECTED DNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, AIDS, CYTOPLASM, TRANSFERASE, VIRAL NUCLEOPROTEIN, HYDROLASE
1c6v:A (THR60) to (ILE165) SIV INTEGRASE (CATALYTIC DOMAIN + DNA BIDING DOMAIN COMPRISING RESIDUES 50-293) MUTANT WITH PHE 185 REPLACED BY HIS (F185H) | DNA INTEGRATION, DNA BINDING PROTEIN
1c6v:D (THR60) to (ILE165) SIV INTEGRASE (CATALYTIC DOMAIN + DNA BIDING DOMAIN COMPRISING RESIDUES 50-293) MUTANT WITH PHE 185 REPLACED BY HIS (F185H) | DNA INTEGRATION, DNA BINDING PROTEIN
1cxu:A (LEU58) to (GLY175) 1.42A RESOLUTION ASV INTEGRASE CORE DOMAIN FROM CITRATE | MIXED BETA-SHEET SURROUNDED BY ALPHA-HELICES, TRANSFERASE
1cz9:A (GLN59) to (GLY175) ATOMIC RESOLUTION ASV INTEGRASE CORE DOMAIN (D64N) FROM CITRATE | MIXED BETA-SHEET SURROUNDED BY ALPHA-HELICES, TRANSFERASE
3t19:A (GLU438) to (VAL552) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (WILD TYPE) IN COMPLEX WITH INHIBITOR M05 | HIV-1 REVERSE TRANSCRIPTASE, NON-NUCLEOSIDE INHIBITION, NUCLEOTIDYLTRASFERASE, HIV-1, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
2rf2:A (GLU438) to (VAL552) HIV REVERSE TRANSCRIPTASE IN COMPLEX WITH INHIBITOR 7E (NNRTI) | HIV-1 REVERS TRANSCRIPTASE, AIS, NON-NUCLEOSIDE INHIBITION, NUCLEOTIDYLTRANSFERASE, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CORE PROTEIN, CYTOPLASM, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HOST-VIRUS INTERACTION, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEUS, PHOSPHORYLATION, PROTEASE, RNA-BINDING, RNA-DIRECTED DNA POLYMERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC, ZINC-FINGER
3u3g:B (ASN2) to (LEU139) STRUCTURE OF LC11-RNASE H1 ISOLATED FROM COMPOST BY METAGENOMIC APPROACH: INSIGHT INTO THE STRUCTURAL BASES FOR UNUSUAL ENZYMATIC PROPERTIES OF STO-RNASE H1 | HYDROLASE, CLEAVE THE RNA STRAND OF RNA/DNA HYBRID
3u3g:A (ASN2) to (LEU139) STRUCTURE OF LC11-RNASE H1 ISOLATED FROM COMPOST BY METAGENOMIC APPROACH: INSIGHT INTO THE STRUCTURAL BASES FOR UNUSUAL ENZYMATIC PROPERTIES OF STO-RNASE H1 | HYDROLASE, CLEAVE THE RNA STRAND OF RNA/DNA HYBRID
1rch:A (GLN4) to (MET142) SOLUTION NMR STRUCTURE OF RIBONUCLEASE HI FROM ESCHERICHIA COLI, 8 STRUCTURES | HYDROLASE, NUCLEASE, ENDONUCLEASE, MAGNESIUM, 3D-STRUCTURE
1s1x:A (GLU438) to (LEU551) CRYSTAL STRUCTURE OF V108I MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH NEVIRAPINE | HIV-1 REVERSE TRANSCRIPTASE, AIDS, NNRTI, NEVIRAPINE, DRUG RESISTANCE MUTATIONS, TRANSFERASE
3hst:D (VAL1) to (ASP131) N-TERMINAL RNASE H DOMAIN OF RV2228C FROM MYCOBACTERIUM TUBERCULOSIS AS A FUSION PROTEIN WITH MALTOSE BINDING PROTEIN | RIBONUCLEASE H1, RV2228C N-TERMINAL DOMAIN, MYCOBACTERIUM, TUBERCULOSIS, FUSION PROTEIN, MALTOSE BINDING PROTEIN, HYDROLASE
1s6q:A (GLU438) to (VAL552) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH JANSSEN-R147681 | AIDS, HIV, DRUG DESIGN, REVERSE TRANSCRIPTASE, RT, PROTEIN-INHIBITOR COMPLEX, DRUG RESISTANCE, TRANSFERASE
3hvt:A (GLU438) to (SER553) STRUCTURAL BASIS OF ASYMMETRY IN THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE HETERODIMER | NUCLEOTIDYLTRANSFERASE
3v1q:A (THR520) to (GLU666) CRYSTAL STRUCTURES OF THE REVERSE TRANSCRIPTASE-ASSOCIATED RIBONUCLEASE H DOMAIN OF XENOTROPIC MURINE LEUKEMIA-VIRUS RELATED VIRUS | REVERSE TRANSCRIPTION, HYDROLASE
3v6d:C (GLU438) to (LEU551) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) CROSS-LINKED WITH AZT-TERMINATED DNA | HIV-1 REVERSE TRANSCRIPTASE, ZIDOVUDINE, RT-DNA COMPLEX, TRANSFERASE- DNA COMPLEX, DRUG RESISTANCE MUTATION, AIDS, DNA RECOMBINATION, DNA- DIRECTED DNA POLYMERASE, RNASE H, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDYLTRANSFERASE, RNA-DIRECTED DNA POLYMERASE TRANSFERASE
4kv8:A (GLU438) to (SER553) CRYSTAL STRUCTURE OF HIV RT IN COMPLEX WITH BILR0355BS | NUCLEOTIDYLTRANSFERASE, TRANSFERASE
1hni:A (GLU438) to (ALA554) STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN A COMPLEX WITH THE NONNUCLEOSIDE INHIBITOR ALPHA-APA R 95845 AT 2.8 ANGSTROMS RESOLUTION | NUCLEOTIDYLTRANSFERASE
2hb5:A (THR24) to (GLU156) CRYSTAL STRUCTURE OF THE MOLONEY MURINE LEUKEMIA VIRUS RNASE H DOMAIN | RNASE H, HYDROLASE
1hqu:A (GLU438) to (SER553) HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 | NUCLEOTIDYLTRANSFERASE
1hrh:A (GLU438) to (VAL552) CRYSTAL STRUCTURE OF THE RIBONUCLEASE H DOMAIN OF HIV-1 REVERSE TRANSCRIPTASE | HYDROLASE(ENDORIBONUCLEASE)
1hrh:B (GLU438) to (VAL552) CRYSTAL STRUCTURE OF THE RIBONUCLEASE H DOMAIN OF HIV-1 REVERSE TRANSCRIPTASE | HYDROLASE(ENDORIBONUCLEASE)
1hyv:A (GLY59) to (VAL165) HIV INTEGRASE CORE DOMAIN COMPLEXED WITH TETRAPHENYL ARSONIUM | DNA INTEGRATION, TRANSFERASE
2i5j:A (GLU438) to (VAL552) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH DHBNH, AN RNASE H INHIBITOR | AIDS, HIV, REVERSE TRANSCRIPTASE, RT, RNASE H INHIBITOR, RNHI, STRUCTURE-BASED DRUG DESIGN, PROTEIN-INHIBITOR COMPLEX, DRUG RESISTANCE, CRYSTAL STRUCTURE, TRANSFERASE
1ikv:A (GLU438) to (ALA554) K103N MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH EFIVARENZ | HETERODIMER, PROTEIN-INHIBITOR COMPLEX, TRANSFERASE
1ikw:A (GLU438) to (ALA554) WILD TYPE HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH EFAVIRENZ | HETERODIMER, PROTEIN-INHIBITOR COMPLEX, TRANSFERASE
1ikx:A (GLU438) to (ALA554) K103N MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH THE INHIBITOR PNU142721 | HETERODIMER, PROTEIN-INHIBITOR COMPLEX, TRANSFERASE
1iky:A (GLU438) to (SER553) HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH THE INHIBITOR MSC194 | HETERODIMER, PROTEIN-INHIBITOR COMPLEX, TRANSFERASE
2ic3:A (GLU438) to (VAL552) CRYSTAL STRUCTURE OF K103N/Y181C MUTANT HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH NONNUCLEOSIDE INHIBITOR HBY 097 | RT, NNRTI, NONNUCLEOSIDE INHIBITOR, DRUG RESISTANCE, HIV, AIDS, DRUG DESIGN, TRANSFERASE
1uwb:A (GLU438) to (ASP549) TYR 181 CYS HIV-1 RT/8-CL TIBO | AIDS, POLYPROTEIN, HYDROLASE, ASPARTYL PROTEASE, ENDONUCLEASE, RNA-DIRECTED DNA POLYMERASE, TYR181CYS HIV-1 RT/8-CL TIBO, DRUG-RESISTANT MUTANT
1jl2:B (LYS3) to (MET143) CRYSTAL STRUCTURE OF TCEO RNASE H-A CHIMERA COMBINING THE FOLDING CORE FROM T. THERMOPHILUS RNASE H AND THE REMAINING REGION OF E. COLI RNASE H | MIXED ALPHA-BETA PROTEIN, HYDROLASE
1jl2:C (LYS3) to (MET143) CRYSTAL STRUCTURE OF TCEO RNASE H-A CHIMERA COMBINING THE FOLDING CORE FROM T. THERMOPHILUS RNASE H AND THE REMAINING REGION OF E. COLI RNASE H | MIXED ALPHA-BETA PROTEIN, HYDROLASE
1jl2:D (LYS3) to (PRO145) CRYSTAL STRUCTURE OF TCEO RNASE H-A CHIMERA COMBINING THE FOLDING CORE FROM T. THERMOPHILUS RNASE H AND THE REMAINING REGION OF E. COLI RNASE H | MIXED ALPHA-BETA PROTEIN, HYDROLASE
1jla:A (GLU438) to (SER553) CRYSTAL STRUCTURE OF Y181C MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH TNK-651 | HIV-1 REVERSE TRANSCRIPTASE, AIDS, NON-NUCLEOSIDE INHIBITOR, TNK-651, DRUG RESISTANCE MUTATIONS, DRUG DESIGN, TRANSFERASE
3zcm:A (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DESIGN. | TRANSFERASE
3zcm:B (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DESIGN. | TRANSFERASE
2lsn:A (VAL9) to (VAL164) SOLUTION STRUCTURE OF PFV RNASE H DOMAIN | RNASE H, VIRAL PROTEIN
3zsq:A (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN | TRANSFERASE, AIDS
3zsq:B (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN | TRANSFERASE, AIDS
3zsr:A (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN | TRANSFERASE, AIDS
3zsr:B (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN | TRANSFERASE, AIDS
3zsv:A (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN | TRANSFERASE, AIDS
3zsv:B (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN | TRANSFERASE, AIDS
3zsw:A (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN | TRANSFERASE, AIDS
3zsw:B (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN | TRANSFERASE, AIDS
3zsx:A (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN | TRANSFERASE, AIDS
3zsx:B (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN | TRANSFERASE, AIDS
3zsy:A (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN | TRANSFERASE, AIDS
3zsy:B (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN | TRANSFERASE, AIDS
3zt1:A (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN | TRANSFERASE, AIDS
3zt1:B (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN | TRANSFERASE, AIDS
3zsz:A (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN | TRANSFERASE, AIDS
3zsz:B (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN | TRANSFERASE, AIDS
3zt2:A (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN | TRANSFERASE, AIDS
3zt2:B (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN | TRANSFERASE, AIDS
3zt4:A (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN | TRANSFERASE, AIDS
3zt4:B (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN | TRANSFERASE, AIDS
3jsm:A (GLU438) to (VAL552) K65R MUTANT HIV-1 REVERSE TRANSCRIPTASE CROSS-LINKED TO DS-DNA AND COMPLEXED WITH TENOFOVIR-DIPHOSPHATE AS THE INCOMING NUCLEOTIDE SUBSTRATE | HIV-1 REVERSE TRANSCRIPTASE, TENOFOVIR, RT-DNA COMPLEX, TRANSFERASE- DNA COMPLEX, DRUG RESISTANCE MUTATION, AIDS, DNA RECOMBINATION, DNA- DIRECTED DNA POLYMERASE, RNASE H, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEOTIDYLTRANSFERASE, RNA-DIRECTED DNA POLYMERASE TRANSFERASE, TRANSFERASE-DNA COMPLEX COMPLEX
2ynh:A (GLU438) to (ALA554) HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH INHIBITOR GSK500 | HYDROLASE, NNRTI
3k2p:A (GLU438) to (VAL552) HIV-1 REVERSE TRANSCRIPTASE ISOLATED RNASEH DOMAIN WITH THE INHIBITOR BETA-THUJAPLICINOL BOUND AT THE ACTIVE SITE | RNASE H INHIBITOR, REVERSE TRANSCRIPTASE, AIDS, HIV, PROTEIN-INHIBITOR COMPLEX, STRUCTURE-BASED DRUG DESIGN, TROPOLONES, TROPYLIUM ION, DIVALENT CATION CHELATOR, METAL- BINDING, RNA-BINDING, HYDROLASE
3k2p:B (GLU438) to (ALA554) HIV-1 REVERSE TRANSCRIPTASE ISOLATED RNASEH DOMAIN WITH THE INHIBITOR BETA-THUJAPLICINOL BOUND AT THE ACTIVE SITE | RNASE H INHIBITOR, REVERSE TRANSCRIPTASE, AIDS, HIV, PROTEIN-INHIBITOR COMPLEX, STRUCTURE-BASED DRUG DESIGN, TROPOLONES, TROPYLIUM ION, DIVALENT CATION CHELATOR, METAL- BINDING, RNA-BINDING, HYDROLASE
1lwe:A (GLU438) to (VAL552) CRYSTAL STRUCTURE OF M41L/T215Y MUTANT HIV-1 REVERSE TRANSCRIPTASE (RTMN) IN COMPLEX WITH NEVIRAPINE | HIV-1 REVERSE TRANSCRIPTASE, AIDS, AZT, 3TC, NRTI, NEVIRAPINE, DRUG RESISTANCE MUTATIONS, TRANSFERASE
4ojr:A (ILE60) to (VAL165) CRYSTAL STRUCTURE OF THE HIV-1 INTEGRASE CATALYTIC DOMAIN WITH GSK1264 | VIRAL DNA INTEGRATION, DNA BINDING, LEDGF BINDING, VIRAL PROTEIN
4ovl:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | HIV INTEGRASE, STRUCTURE BASED DRUG DESIGN
3kle:E (ALA437) to (LEU551) CRYSTAL STRUCTURE OF AZT-RESISTANT HIV-1 REVERSE TRANSCRIPTASE CROSSLINKED TO A DSDNA WITH A BOUND EXCISION PRODUCT, AZTPPPPA | AZT RESISTANCE MECHANISM, HIV-1, REVERSE TRANSCRIPTASE, RT, AZT, RESISTANCE MUTATIONS, P51/P66, NUCLEOSIDE INHIBITOR, NUCLEOTIDE EXCISION, THYMIDINE ANALOG MUTATIONS, AIDS, HIV, DNA POLYMERASE, NRTI, NRTI RESISTANCE, AZTPPPPA, AZTP4A, AZT ADENOSINE DINUCLEOSIDE TETRAPHOSPHATE, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, MAGNESIUM, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, TRANSFERASE-DNA COMPLEX
3kle:M (ALA437) to (ILE556) CRYSTAL STRUCTURE OF AZT-RESISTANT HIV-1 REVERSE TRANSCRIPTASE CROSSLINKED TO A DSDNA WITH A BOUND EXCISION PRODUCT, AZTPPPPA | AZT RESISTANCE MECHANISM, HIV-1, REVERSE TRANSCRIPTASE, RT, AZT, RESISTANCE MUTATIONS, P51/P66, NUCLEOSIDE INHIBITOR, NUCLEOTIDE EXCISION, THYMIDINE ANALOG MUTATIONS, AIDS, HIV, DNA POLYMERASE, NRTI, NRTI RESISTANCE, AZTPPPPA, AZTP4A, AZT ADENOSINE DINUCLEOSIDE TETRAPHOSPHATE, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, MAGNESIUM, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, TRANSFERASE-DNA COMPLEX
3klf:A (GLU438) to (SER553) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 REVERSE TRANSCRIPTASE CROSSLINKED TO A DSDNA WITH A BOUND EXCISION PRODUCT, AZTPPPPA | AZT RESISTANCE MECHANISM, HIV-1 REVERSE TRANSCRIPTASE, WILD-TYPE, AZT RESISTANCE MUTATIONS, P51/P66, NUCELEOSIDE INHIBITOR, THYMIDINE ANALOG MUTATIONS, AIDS, HIV, DNA POLYMERASE, NRTI, NRTI RESISTANCE, AZT, AZTPPPPA, AZTP4A, DINUCLEOSIDE TETRAPHOSPHATE, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, MAGNESIUM, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEASE, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, TRANSFERASE-DNA COMPLEX
3klf:I (GLU438) to (ALA554) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 REVERSE TRANSCRIPTASE CROSSLINKED TO A DSDNA WITH A BOUND EXCISION PRODUCT, AZTPPPPA | AZT RESISTANCE MECHANISM, HIV-1 REVERSE TRANSCRIPTASE, WILD-TYPE, AZT RESISTANCE MUTATIONS, P51/P66, NUCELEOSIDE INHIBITOR, THYMIDINE ANALOG MUTATIONS, AIDS, HIV, DNA POLYMERASE, NRTI, NRTI RESISTANCE, AZT, AZTPPPPA, AZTP4A, DINUCLEOSIDE TETRAPHOSPHATE, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, MAGNESIUM, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEASE, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, TRANSFERASE-DNA COMPLEX
3klf:M (GLU438) to (ALA554) CRYSTAL STRUCTURE OF WILD-TYPE HIV-1 REVERSE TRANSCRIPTASE CROSSLINKED TO A DSDNA WITH A BOUND EXCISION PRODUCT, AZTPPPPA | AZT RESISTANCE MECHANISM, HIV-1 REVERSE TRANSCRIPTASE, WILD-TYPE, AZT RESISTANCE MUTATIONS, P51/P66, NUCELEOSIDE INHIBITOR, THYMIDINE ANALOG MUTATIONS, AIDS, HIV, DNA POLYMERASE, NRTI, NRTI RESISTANCE, AZT, AZTPPPPA, AZTP4A, DINUCLEOSIDE TETRAPHOSPHATE, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HYDROLASE, MAGNESIUM, METAL-BINDING, MULTIFUNCTIONAL ENZYME, NUCLEASE, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, TRANSFERASE-DNA COMPLEX
5d3g:A (GLU438) to (VAL552) STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE BOUND TO A NOVEL 38-MER HAIRPIN TEMPLATE-PRIMER DNA APTAMER | REVERSE TRANSCRIPTASE, HIV, DNA APTAMER, 2-O-METHYLCYTIDINE, P66, P51, TRANSFERASE
4ah9:A (GLY59) to (VAL165) PARALLEL SCREENING OF A LOW MOLECULAR WEIGHT COMPOUND LIBRARY: DO DIFFERENCES IN METHODOLOGY AFFECT HIT IDENTIFICATION | TRANSFERASE, FRAGMENT SCREENING
4ah9:B (ILE60) to (VAL165) PARALLEL SCREENING OF A LOW MOLECULAR WEIGHT COMPOUND LIBRARY: DO DIFFERENCES IN METHODOLOGY AFFECT HIT IDENTIFICATION | TRANSFERASE, FRAGMENT SCREENING
4ahr:A (ILE60) to (VAL165) PARALLEL SCREENING OF A LOW MOLECULAR WEIGHT COMPOUND LIBRARY: DO DIFFERENCES IN METHODOLOGY AFFECT HIT IDENTIFICATION | TRANSFERASE, FRAGMENT SCREENING
4ahr:B (ILE60) to (VAL165) PARALLEL SCREENING OF A LOW MOLECULAR WEIGHT COMPOUND LIBRARY: DO DIFFERENCES IN METHODOLOGY AFFECT HIT IDENTIFICATION | TRANSFERASE, FRAGMENT SCREENING
4ahs:B (ILE60) to (VAL165) PARALLEL SCREENING OF A LOW MOLECULAR WEIGHT COMPOUND LIBRARY: DO DIFFERENCES IN METHODOLOGY AFFECT HIT IDENTIFICATION | TRANSFERASE
4aht:A (ILE60) to (VAL165) PARALLEL SCREENING OF A LOW MOLECULAR WEIGHT COMPOUND LIBRARY: DO DIFFERENCES IN METHODOLOGY AFFECT HIT IDENTIFICATION | TRANSFERASE, FRAGMENT SCREENING
4aht:B (ILE60) to (VAL165) PARALLEL SCREENING OF A LOW MOLECULAR WEIGHT COMPOUND LIBRARY: DO DIFFERENCES IN METHODOLOGY AFFECT HIT IDENTIFICATION | TRANSFERASE, FRAGMENT SCREENING
4ahu:A (ILE60) to (VAL165) PARALLEL SCREENING OF A LOW MOLECULAR WEIGHT COMPOUND LIBRARY: DO DIFFERENCES IN METHODOLOGY AFFECT HIT IDENTIFICATION | TRANSFERASE, FRAGMENT SCREENING
4ahu:B (ILE60) to (VAL165) PARALLEL SCREENING OF A LOW MOLECULAR WEIGHT COMPOUND LIBRARY: DO DIFFERENCES IN METHODOLOGY AFFECT HIT IDENTIFICATION | TRANSFERASE, FRAGMENT SCREENING
4ahv:A (ILE60) to (VAL165) PARALLEL SCREENING OF A LOW MOLECULAR WEIGHT COMPOUND LIBRARY: DO DIFFERENCES IN METHODOLOGY AFFECT HIT IDENTIFICATION | TRANSFERASE
4ahv:B (ILE60) to (VAL165) PARALLEL SCREENING OF A LOW MOLECULAR WEIGHT COMPOUND LIBRARY: DO DIFFERENCES IN METHODOLOGY AFFECT HIT IDENTIFICATION | TRANSFERASE
1mu2:A (GLU437) to (VAL551) CRYSTAL STRUCTURE OF HIV-2 REVERSE TRANSCRIPTASE | HIV-2 REVERSE TRANSCRIPTASE, AIDS, POLYMERASE, DRUG DESIGN, TRANSFERASE
3lal:A (GLU438) to (VAL552) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH N1-ETHYL PYRIMIDINEDIONE NON-NUCLEOSIDE INHIBITOR | HIV, RT, NNRTI, TRANSFERASE
3lan:A (GLU438) to (VAL552) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH N1-BUTYL PYRIMIDINEDIONE NON-NUCLEOSIDE INHIBITOR | HIV, REVERSE TRANSCRIPTASE, RT, NNRTI, TRANSFERASE
4puo:C (GLU438) to (VAL552) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH RNA/DNA AND NEVIRAPINE | FINGERS, PALM, THUMB, CONNECTION, RNASE H, NUCLEOTIDYLTRANSFERASE, DNA-DIRECTED DNA POLYMERASE, RNA-DIRECTED DNA POLYMERASE, NUCLEASE, RIBONUCLEASE H, TRNA, TRANSFERASE, HYDROLASE-DNA-RNA-INHIBITOR COMPLEX
4pwd:C (GLU438) to (VAL552) CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH BULGE-RNA/DNA AND NEVIRAPINE | FINGERS, PALM, THUMB, CONNECTION, RNASE H, NUCLEOTIDYLTRANSFERASE, DNA-DIRECTED DNA POLYMERASE, RNA-DIRECTED DNA POLYMERASE, NUCLEASE, RIBONUCLEASE H, TRNA, TRANSFERASE, HYDROLASE-DNA-RNA-INHIBITOR COMPLEX
3lp3:A (GLU438) to (VAL552) P15 HIV RNASEH DOMAIN WITH INHIBITOR MK3 | REVERSE TRANSCRIPTASE, RNASE H, HIV, AIDS, CAPSID MATURATION, DNA INTEGRATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HOST CYTOPLASM, HOST NUCLEUS, MULTIFUNCTIONAL ENZYME, RNA-BINDING, RNA- DIRECTED DNA POLYMERASE, VIRAL NUCLEOPROTEIN, VIRION, VIRAL PROTEIN
3lp3:B (GLU438) to (VAL552) P15 HIV RNASEH DOMAIN WITH INHIBITOR MK3 | REVERSE TRANSCRIPTASE, RNASE H, HIV, AIDS, CAPSID MATURATION, DNA INTEGRATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HOST CYTOPLASM, HOST NUCLEUS, MULTIFUNCTIONAL ENZYME, RNA-BINDING, RNA- DIRECTED DNA POLYMERASE, VIRAL NUCLEOPROTEIN, VIRION, VIRAL PROTEIN
3av9:A (ILE60) to (VAL165) CRYSTAL STRUCTURES OF NOVEL ALLOSTERIC PEPTIDE INHIBITORS OF HIV INTEGRASE IN THE LEDGF BINDING SITE | PROTEIN-PROTEIN INTERACTIONS, HIV, RECOMBINATION-INHIBITOR COMPLEX
3av9:B (ILE60) to (VAL165) CRYSTAL STRUCTURES OF NOVEL ALLOSTERIC PEPTIDE INHIBITORS OF HIV INTEGRASE IN THE LEDGF BINDING SITE | PROTEIN-PROTEIN INTERACTIONS, HIV, RECOMBINATION-INHIBITOR COMPLEX
3avc:A (ILE60) to (VAL165) CRYSTAL STRUCTURES OF NOVEL ALLOSTERIC PEPTIDE INHIBITORS OF HIV INTEGRASE IN THE LEDGF BINDING SITE | PROTEIN-PROTEIN INTERACTIONS, HIV, RECOMBINATION-INHIBITOR COMPLEX
3avc:B (ILE60) to (VAL165) CRYSTAL STRUCTURES OF NOVEL ALLOSTERIC PEPTIDE INHIBITORS OF HIV INTEGRASE IN THE LEDGF BINDING SITE | PROTEIN-PROTEIN INTERACTIONS, HIV, RECOMBINATION-INHIBITOR COMPLEX
3avf:A (ILE60) to (VAL165) CRYSTAL STRUCTURES OF NOVEL ALLOSTERIC PEPTIDE INHIBITORS OF HIV INTEGRASE IN THE LEDGF BINDING SITE | PROTEIN-PROTEIN INTERACTIONS, HIV, RECOMBINATION-INHIBITOR COMPLEX
3avh:A (ILE60) to (VAL165) CRYSTAL STRUCTURES OF NOVEL ALLOSTERIC PEPTIDE INHIBITORS OF HIV INTEGRASE IN THE LEDGF BINDING SITE | PROTEIN-PROTEIN INTERACTIONS, HIV, RECOMBINATION-INHIBITOR COMPLEX
3avi:B (ILE60) to (VAL165) CRYSTAL STRUCTURES OF NOVEL ALLOSTERIC PEPTIDE INHIBITORS OF HIV INTEGRASE IN THE LEDGF BINDING SITE | PROTEIN-PROTEIN INTERACTIONS, HIV, RECOMBINATION-INHIBITOR COMPLEX
3avj:A (ILE60) to (VAL165) CRYSTAL STRUCTURES OF NOVEL ALLOSTERIC PEPTIDE INHIBITORS OF HIV INTEGRASE IN THE LEDGF BINDING SITE | PROTEIN-PROTEIN INTERACTIONS, HIV, RECOMBINATION-INHIBITOR COMPLEX
3avj:B (ILE60) to (VAL165) CRYSTAL STRUCTURES OF NOVEL ALLOSTERIC PEPTIDE INHIBITORS OF HIV INTEGRASE IN THE LEDGF BINDING SITE | PROTEIN-PROTEIN INTERACTIONS, HIV, RECOMBINATION-INHIBITOR COMPLEX
3avk:A (ILE60) to (VAL165) CRYSTAL STRUCTURES OF NOVEL ALLOSTERIC PEPTIDE INHIBITORS OF HIV INTEGRASE IN THE LEDGF BINDING SITE | PROTEIN-PROTEIN INTERACTIONS, HIV, RECOMBINATION-INHIBITOR COMPLEX
3avk:B (ILE60) to (VAL165) CRYSTAL STRUCTURES OF NOVEL ALLOSTERIC PEPTIDE INHIBITORS OF HIV INTEGRASE IN THE LEDGF BINDING SITE | PROTEIN-PROTEIN INTERACTIONS, HIV, RECOMBINATION-INHIBITOR COMPLEX
3avl:A (ILE60) to (VAL165) CRYSTAL STRUCTURES OF NOVEL ALLOSTERIC PEPTIDE INHIBITORS OF HIV INTEGRASE IN THE LEDGF BINDING SITE | PROTEIN-PROTEIN INTERACTIONS, HIV, RECOMBINATION-INHIBITOR COMPLEX
3avl:B (ILE60) to (VAL165) CRYSTAL STRUCTURES OF NOVEL ALLOSTERIC PEPTIDE INHIBITORS OF HIV INTEGRASE IN THE LEDGF BINDING SITE | PROTEIN-PROTEIN INTERACTIONS, HIV, RECOMBINATION-INHIBITOR COMPLEX
3avm:A (ILE60) to (VAL165) CRYSTAL STRUCTURES OF NOVEL ALLOSTERIC PEPTIDE INHIBITORS OF HIV INTEGRASE IN THE LEDGF BINDING SITE | PROTEIN-PROTEIN INTERACTIONS, HIV, RECOMBINATION-INHIBITOR COMPLEX
3avm:B (ILE60) to (VAL165) CRYSTAL STRUCTURES OF NOVEL ALLOSTERIC PEPTIDE INHIBITORS OF HIV INTEGRASE IN THE LEDGF BINDING SITE | PROTEIN-PROTEIN INTERACTIONS, HIV, RECOMBINATION-INHIBITOR COMPLEX
3avn:A (ILE60) to (VAL165) CRYSTAL STRUCTURES OF NOVEL ALLOSTERIC PEPTIDE INHIBITORS OF HIV INTEGRASE IN THE LEDGF BINDING SITE | PROTEIN-PROTEIN INTERACTIONS, HIV, RECOMBINATION-INHIBITOR COMPLEX
3avn:B (ILE60) to (VAL165) CRYSTAL STRUCTURES OF NOVEL ALLOSTERIC PEPTIDE INHIBITORS OF HIV INTEGRASE IN THE LEDGF BINDING SITE | PROTEIN-PROTEIN INTERACTIONS, HIV, RECOMBINATION-INHIBITOR COMPLEX
4qag:A (GLU438) to (VAL552) STRUCTURE OF A DIHYDROXYCOUMARIN ACTIVE-SITE INHIBITOR IN COMPLEX WITH THE RNASE H DOMAIN OF HIV-1 REVERSE TRANSCRIPTASE | RNASE H INHIBITOR, STRUCTURE-BASED DRUG DESIGN, ACTIVE SITE, TRANSFERASE, DIHYDROXYCOUMARIN ANALOGS, DIHYDROXY-BENZOPYRONE DERIVATIVES, DIVALENT CATION CHELATOR, AIDS, REVERSE TRANSCRIPTASE, PROTEIN-INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4qag:B (GLU438) to (VAL552) STRUCTURE OF A DIHYDROXYCOUMARIN ACTIVE-SITE INHIBITOR IN COMPLEX WITH THE RNASE H DOMAIN OF HIV-1 REVERSE TRANSCRIPTASE | RNASE H INHIBITOR, STRUCTURE-BASED DRUG DESIGN, ACTIVE SITE, TRANSFERASE, DIHYDROXYCOUMARIN ANALOGS, DIHYDROXY-BENZOPYRONE DERIVATIVES, DIVALENT CATION CHELATOR, AIDS, REVERSE TRANSCRIPTASE, PROTEIN-INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4b3o:A (GLU438) to (SER553) STRUCTURES OF HIV-1 RT AND RNA-DNA COMPLEX REVEAL A UNIQUE RT CONFORMATION AND SUBSTRATE INTERFACE | HYDROLASE-DNA-RNA COMPLEX, RNASE H, SUBUNIT INTERFACE
4b3q:A (GLU438) to (SER553) STRUCTURES OF HIV-1 RT AND RNA-DNA COMPLEX REVEAL A UNIQUE RT CONFORMATION AND SUBSTRATE INTERFACE | HYDROLASE-DNA-RNA COMPLEX, RNASE H, HYBRID
3m8q:A (GLU438) to (ALA554) HIV-1 RT WITH AMINOPYRIMIDINE NNRTI | HIV, RT, REVERSE TRANSCRIPTASE RIBONUCLEASE H, TRANSFERASE RNA- DIRECTED DNA POLYMERASE, NUCLEOTIDYLTRANSFERASE, HYDROLASE, TRANSFERASE
5ejk:B (GLN59) to (GLY175) CRYSTAL STRUCTURE OF THE ROUS SARCOMA VIRUS INTASOME | RSV, INTEGRASE, INTASOME, TRANSFERASE-DNA COMPLEX
3c6u:A (GLU438) to (LEU551) CRYSTAL STRUCTURE OF HIV REVERSE TRANSCRIPTASE IN COMPLEX WITH INHIBITOR 22 | HIV-1 REVERSE TRANSCRIPTASE, NON-NUCLEOSIDE INHIBITION, NUCLEOTIDYLTRASFERASE, AIDS, ASPARTYL PROTEASE, CAPSID MATURATION, CAPSID PROTEIN, CYTOPLASM, DNA INTEGRATION, DNA RECOMBINATION, DNA-DIRECTED DNA POLYMERASE, ENDONUCLEASE, HOST-VIRUS INTERACTION, HYDROLASE, LIPOPROTEIN, MAGNESIUM, MEMBRANE, METAL-BINDING, MULTIFUNCTIONAL ENZYME, MYRISTATE, NUCLEASE, NUCLEOTIDYLTRANSFERASE, NUCLEUS, PHOSPHOPROTEIN, PROTEASE, RNA-BINDING, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, VIRAL NUCLEOPROTEIN, VIRION, ZINC, ZINC-FINGER
3nf6:A (ILE60) to (VAL165) STRUCTURAL BASIS FOR A NEW MECHANISM OF INHIBITION OF HIV INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DESIGN | INTEGRASE, INTEGRATION, DNA, SEE MUTATIONS, INTRA-CELLULAR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4ce9:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4ce9:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cea:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cea:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4ceb:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4ceb:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cec:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cec:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4ced:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4ced:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cee:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, DNA INTEGRATION, STRUCTURE BASED DRUG DESIGN, RNA-DIRECTED DNA POLYMERASE
4cee:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, DNA INTEGRATION, STRUCTURE BASED DRUG DESIGN, RNA-DIRECTED DNA POLYMERASE
4cef:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, DNA INTEGRATION, STRUCTURE BASED DRUG DESIGN, RNA-DIRECTED DNA POLYMERASE
4cef:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, DNA INTEGRATION, STRUCTURE BASED DRUG DESIGN, RNA-DIRECTED DNA POLYMERASE
4ceo:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, DNA INTEGRATION, STRUCTURE BASED DRUG DESIGN, RNA-DIRECTED DNA POLYMERASE
4ceo:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, DNA INTEGRATION, STRUCTURE BASED DRUG DESIGN, RNA-DIRECTED DNA POLYMERASE
4ceq:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4ceq:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4ces:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4ces:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cez:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cez:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cf1:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cf1:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cf9:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cf9:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cfa:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cfa:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cfb:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cfb:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cfc:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cfc:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cfd:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cfd:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cgd:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cgf:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, HIV INTEGRASE, STRUCTURE BASED DRUG DESIGN
4cgf:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, HIV INTEGRASE, STRUCTURE BASED DRUG DESIGN
4cgg:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, HIV INTEGRASE, STRUCTURE BASED DRUG DESIGN
4cgg:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, HIV INTEGRASE, STRUCTURE BASED DRUG DESIGN
4cgh:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, HIV INTEGRASE, STRUCTURE BASED DRUG DESIGN
4cgh:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, HIV INTEGRASE, STRUCTURE BASED DRUG DESIGN
4cgi:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cgi:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cgj:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cgj:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4chn:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4chn:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4chp:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4chy:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4chy:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4chz:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4chz:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cie:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, HIV INTEGRASE, STRUCTURE BASED DRUG DESIGN
4cie:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, HIV INTEGRASE, STRUCTURE BASED DRUG DESIGN
4cif:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cif:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cig:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cig:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cj3:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cj3:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cj5:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cj5:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cje:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cje:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cjf:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cjf:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cjk:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cjk:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cjl:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cjp:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cjp:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cjq:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cjq:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cjr:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cjr:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cjs:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cjs:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cjt:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cjt:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cjv:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cjv:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cjw:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cjw:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4ck1:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4ck1:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4ck2:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4ck2:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
3drp:A (GLU438) to (VAL552) HIV REVERSE TRANSCRIPTASE IN COMPLEX WITH INHIBITOR R8E | HIV-1 REVERSE TRANSCRIPTASE, NON-NUCLEOSIDE INHIBITION, NUCLEOTIDYLTRASFERASE, HYDROLASE, TRANSFERASE
3p1g:A (THR520) to (GLU666) CRYSTAL STRUCTURE OF THE XENOTROPIC MURINE LEUKEMIA VIRUS-RELATED VIRUS (XMRV) RNASE H DOMAIN | XMRV, RNASE H, REVERSE TRANSCRIPTASE, TRANSCRIPTION
5hlf:A (GLU438) to (VAL552) STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH A 38-MER HAIRPIN TEMPLATE-PRIMER DNA APTAMER AND AN ALPHA-CARBOXYPHOSPHONATE INHIBITOR | DNA APTAMER, 2-O-METHYLCYTIDINE, P51, P66, TRANSFERASE, NCRTI, NUCLEOTIDE COMPETING, INHIBITOR, TRANSFERASE-INHIBITOR-DNA COMPLEX
5hlf:C (GLU438) to (VAL552) STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH A 38-MER HAIRPIN TEMPLATE-PRIMER DNA APTAMER AND AN ALPHA-CARBOXYPHOSPHONATE INHIBITOR | DNA APTAMER, 2-O-METHYLCYTIDINE, P51, P66, TRANSFERASE, NCRTI, NUCLEOTIDE COMPETING, INHIBITOR, TRANSFERASE-INHIBITOR-DNA COMPLEX
5i42:A (GLU438) to (LEU551) STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH A DNA APTAMER, AZTTP, AND CA(2+) ION | RT, DNA APTAMER, AZTTP, POLYMERASE, P SITE COMPLEX, 2-O- METHYLCYTIDINE, TRANSFERASE-DNA COMPLEX
4e89:A (THR520) to (ALA663) CRYSTAL STRUCTURE OF RNASEH FROM GAMMARETROVIRUS | ROSSMANN FOLD, HYDROLASE
5j2m:A (GLU438) to (VAL552) HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH DNA AND EFDA-TRIPHOSPHATE, A TRANSLOCATION-DEFECTIVE RT INHIBITOR | HIV-1, REVERSE TRANSCRIPTASE, RT, DNA, DOUBLE STRANDED DNA, DSDNA, EFDA, 4'-ETHYNYL-2-FLUORO-2'-DEOXYADENOSINE, EFDA-TRIPHOSPHATE, EFDA-TP, INHIBITORS, NRTI, TDRTI, TRANSLOCATION DEFECTIVE, TRANSFERASE-DNA COMPLEX
5j2p:A (GLU438) to (SER553) HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH DNA THAT HAS INCORPORATED EFDA-MP AT THE P-(POST-TRANSLOCATION) SITE AND A SECOND EFDA-MP AT THE N-(PRE-TRANSLOCATION) SITE | HIV-1, REVERSE TRANSCRIPTASE, RT, DNA, DOUBLE STRANDED DNA, DSDNA, EFDA, 4'-ETHYNYL-2-FLUORO-2'-DEOXYADENOSINE, EFDA-MONOPHOSPHATE, EFDA-MP, INHIBITORS, NRTI, TDRTI, TRANSLOCATION DEFECTIVE, P SITE, N SITE, PRE-TRANSLOCATION, POST-TRANSLOCATION, TRANSFERASE-DNA COMPLEX
3qin:A (GLU438) to (VAL552) CRYSTAL STRUCTURE OF HIV-1 RNASE H P15 WITH ENGINEERED E. COLI LOOP AND PYRIMIDINOL CARBOXYLIC ACID INHIBITOR | RNASE H, HIV-1, INHIBITOR, NUCLEASE, TRANSFERASE, HYDROLASE-INHIBITOR COMPLEX
3qio:A (GLU438) to (VAL552) CRYSTAL STRUCTURE OF HIV-1 RNASE H WITH ENGINEERED E. COLI LOOP AND N- HYDROXY QUINAZOLINEDIONE INHIBITOR | RNASE H, HIV-1, INHIBITOR, NUCLEASE, TRANSFERASE, HYDROLASE-INHIBITOR COMPLEX
4fw1:B (GLN59) to (GLY175) CRYSTAL STRUCTURE OF TWO-DOMAIN RSV INTEGRASE COVALENTLY LINKED WITH DNA | DNA BINDING PROTEIN
4fw2:A (GLN59) to (GLY175) CRYSTAL STRUCTURE OF RSV THREE-DOMAIN INTEGRASE WITH DISORDERED N- TERMINAL DOMAIN | DNA BINDING PROTEIN
1eet:A (GLU438) to (ALA554) HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH THE INHIBITOR MSC204 | HETERODIMER, PROTEIN-INHIBITOR COMPLEX, VIRAL PROTEIN, TRANSFERASE
3hyf:A (GLU438) to (SER553) CRYSTAL STRUCTURE OF HIV-1 RNASE H P15 WITH ENGINEERED E. COLI LOOP AND ACTIVE SITE INHIBITOR | RNASE H, HIV-1, HYDROLASE, DI-VALENT METAL NUCLEIC ACID CLEAVAGE MECHANISM, DI-VALENT METAL COORDINATION, ASPARTYL PROTEASE, DNA INTEGRATION, DNA RECOMBINATION, ENDONUCLEASE, MULTIFUNCTIONAL ENZYME, NUCLEASE, NUCLEOTIDYLTRANSFERASE, PROTEASE, RNA-DIRECTED DNA POLYMERASE, TRANSFERASE, MAGNESIUM, METAL-BINDING
3isn:C (GLU438) to (LEU551) CRYSTAL STRUCTURE OF HIV-1 RT BOUND TO A 6-VINYLPYRIMIDINE INHIBITOR | HIV-1, INHIBITOR, RT, TRANSFERASE, HYDROLASE
3vq9:A (ILE60) to (VAL165) HIV-1 IN CORE DOMAIN IN COMPLEX WITH 6-FLUORO-1,3-BENZOTHIAZOL-2-AMINE | RNASEH, DNA BINDING, DNA CLEAVAGE, DNA INTEGRATION, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
3vq9:B (ILE60) to (ARG166) HIV-1 IN CORE DOMAIN IN COMPLEX WITH 6-FLUORO-1,3-BENZOTHIAZOL-2-AMINE | RNASEH, DNA BINDING, DNA CLEAVAGE, DNA INTEGRATION, TRANSFERASE- TRANSFERASE INHIBITOR COMPLEX
1k6y:C (ILE60) to (VAL165) CRYSTAL STRUCTURE OF A TWO-DOMAIN FRAGMENT OF HIV-1 INTEGRASE | HIV-1, INTEGRASE, DOMAIN ORGANIZATION, TRANSFERASE
3zso:A (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DESIGN | TRANSFERASE, AIDS
3zso:B (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DESIGN | TRANSFERASE, AIDS
3zt0:A (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN | TRANSFERASE, AIDS
3zt0:B (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN | TRANSFERASE, AIDS
3zt3:A (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN | TRANSFERASE, AIDS
3zt3:B (ILE60) to (VAL165) SMALL MOLECULE INHIBITORS OF THE LEDGF SITE OF HIV TYPE 1 INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DRUG DESIGN | TRANSFERASE, AIDS
4nyf:A (ILE60) to (GLY149) HIV INTEGRASE IN COMPLEX WITH INHIBITOR | ALLOSTERIC INHIBITOR, NCINI, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
3kk1:A (GLU438) to (VAL552) HIV-1 REVERSE TRANSCRIPTASE-DNA COMPLEX WITH NUCEOTIDE INHIBITOR GS- 9148-DIPHOSPHATE BOUND IN NUCLEOTIDE SITE | HIV, REVERSE TRANSCRIPTASE, PROTEIN-DNA COMPLEX, TRANSFERASE-DNA COMPLEX
5dmr:A (THR520) to (ILE661) CRYSTAL STRUCTURE OF C-TERMINAL DOMAIN OF MOUSE ERF1 IN COMPLEX WITH RNASE H DOMAIN OF RT OF MOLONEY MURINE LEUKEMIA VIRUS | ERF1, RT, COMPLEX, HYDROLASE-TRANSLATION COMPLEX
3ava:A (ILE60) to (VAL165) CRYSTAL STRUCTURES OF NOVEL ALLOSTERIC PEPTIDE INHIBITORS OF HIV INTEGRASE IN THE LEDGF BINDING SITE | PROTEIN-PROTEIN INTERACTIONS, HIV, RECOMBINATION-INHIBITOR COMPLEX
3ava:B (ILE60) to (VAL165) CRYSTAL STRUCTURES OF NOVEL ALLOSTERIC PEPTIDE INHIBITORS OF HIV INTEGRASE IN THE LEDGF BINDING SITE | PROTEIN-PROTEIN INTERACTIONS, HIV, RECOMBINATION-INHIBITOR COMPLEX
3avb:A (ILE60) to (VAL165) CRYSTAL STRUCTURES OF NOVEL ALLOSTERIC PEPTIDE INHIBITORS OF HIV INTEGRASE IN THE LEDGF BINDING SITE | PROTEIN-PROTEIN INTERACTIONS, HIV, RECOMBINATION-INHIBITOR COMPLEX
3avb:B (ILE60) to (VAL165) CRYSTAL STRUCTURES OF NOVEL ALLOSTERIC PEPTIDE INHIBITORS OF HIV INTEGRASE IN THE LEDGF BINDING SITE | PROTEIN-PROTEIN INTERACTIONS, HIV, RECOMBINATION-INHIBITOR COMPLEX
3avg:B (ILE60) to (VAL165) CRYSTAL STRUCTURES OF NOVEL ALLOSTERIC PEPTIDE INHIBITORS OF HIV INTEGRASE IN THE LEDGF BINDING SITE | PROTEIN-PROTEIN INTERACTIONS, HIV, RECOMBINATION-INHIBITOR COMPLEX
3mee:A (GLU438) to (VAL552) HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH TMC278 | HIV, REVERSE TRANSCRIPTASE, TMC278, RILPIVIRINE, NNRTI, TRANSFERASE
3nf7:A (ILE60) to (VAL165) STRUCTURAL BASIS FOR A NEW MECHANISM OF INHIBITION OF HIV INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DESIGN | INTEGRASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3nf7:B (ILE60) to (VAL165) STRUCTURAL BASIS FOR A NEW MECHANISM OF INHIBITION OF HIV INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DESIGN | INTEGRASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3nf9:A (ILE60) to (VAL165) STRUCTURAL BASIS FOR A NEW MECHANISM OF INHIBITION OF HIV INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DESIGN | INTEGRASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3nf9:B (ILE60) to (VAL165) STRUCTURAL BASIS FOR A NEW MECHANISM OF INHIBITION OF HIV INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DESIGN | INTEGRASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3nfa:A (ILE60) to (VAL165) STRUCTURAL BASIS FOR A NEW MECHANISM OF INHIBITION OF HIV INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DESIGN | INTEGRASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
3nfa:B (ILE60) to (VAL165) STRUCTURAL BASIS FOR A NEW MECHANISM OF INHIBITION OF HIV INTEGRASE IDENTIFIED BY FRAGMENT SCREENING AND STRUCTURE BASED DESIGN | INTEGRASE, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
4cer:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cer:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cf0:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cf0:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cf2:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, HIV INTEGRASE, STRUCTURE BASED DRUG DESIGN
4cf2:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, HIV INTEGRASE, STRUCTURE BASED DRUG DESIGN
4cf8:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cf8:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cho:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cho:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4chq:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4chq:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cj4:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cj4:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cju:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4cju:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4ck3:A (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
4ck3:B (ILE60) to (VAL165) INTERROGATING HIV INTEGRASE FOR COMPOUNDS THAT BIND- A SAMPL CHALLENGE | TRANSFERASE, STRUCTURE BASED DRUG DESIGN
3e01:A (GLU438) to (ALA554) HIV-RT WITH NON-NUCLEOSIDE INHIBITOR ANNULATED PYRAZOLE 2 | TRANSFERASE
5krt:A (GLY59) to (VAL165) HIV-1 INTEGRASE CATALYTIC CORE DOMAIN (CCD) IN COMPLEX WITH A FRAGMENT-DERIVED ALLOSTERIC INHIBITOR | HIV-1 INTEGRASE; CATALYTIC CORE DOMAIN (CCD); P75/LEDGF INHIBITOR, HYDROLASE, TRANSFERASE-INHIBITOR COMPLEX