2agt:A (GLY16) to (SER290) ALDOSE REDUCTASE MUTANT LEU 300 PRO COMPLEXED WITH FIDARESTAT | OXIDOREDUCTASE, NADP, FIDARESTAT,
4wdt:A (LEU19) to (GLY298) 17BETA-HSD5 IN COMPLEX WITH 2-NITRO-5-(PHENYLSULFONYL)PHENOL | ALDO-KETO REDUCTASE INHIBITOR
4wdu:A (LEU19) to (GLY298) 17BETA-HSD5 IN COMPLEX WITH 4-CHLORO-N-(4-CHLOROBENZYL)-5-NITRO-1H- PYRAZOLE-3-CARBOXAMIDE | ALDO-KETO REDUCTASE INHIBITOR
4wdw:A (LEU19) to (GLY298) 17BETA-HSD5 IN COMPLEX WITH 3,6-DIHYDROPYRIDIN-1(2H)-YL(5-METHYL-1H- INDOL-2-YL)METHANONE | ALDO-KETO REDUCTASE INHIBITOR
4wdw:B (LEU19) to (GLY298) 17BETA-HSD5 IN COMPLEX WITH 3,6-DIHYDROPYRIDIN-1(2H)-YL(5-METHYL-1H- INDOL-2-YL)METHANONE | ALDO-KETO REDUCTASE INHIBITOR
4wdx:A (LEU19) to (GLY298) 17BETA-HSD5 IN COMPLEX WITH [4-(2-HYDROXYETHYL)PIPERIDIN-1-YL](5- METHYL-1H-INDOL-2-YL)METHANONE | ALDO-KETO REDUCTASE INHIBITOR
4wdx:B (LEU19) to (GLY298) 17BETA-HSD5 IN COMPLEX WITH [4-(2-HYDROXYETHYL)PIPERIDIN-1-YL](5- METHYL-1H-INDOL-2-YL)METHANONE | ALDO-KETO REDUCTASE INHIBITOR
1a80:A (GLY18) to (PRO263) NATIVE 2,5-DIKETO-D-GLUCONIC ACID REDUCTASE A FROM CORYNBACTERIUM SP. COMPLEXED WITH NADPH | OXIDOREDUCTASE, ALPHA8/BETA8 BARREL, 2, 5-DIKETO-D-GLUCONIC ACID, COMMERCIAL VITAMIN C SYNTHESIS
1ah0:A (GLY16) to (SER290) PIG ALDOSE REDUCTASE COMPLEXED WITH SORBINIL | OXIDOREDUCTASE, SORBINIL INHIBITOR, DIABETES
1ah3:A (GLY16) to (SER290) ALDOSE REDUCTASE COMPLEXED WITH TOLRESTAT INHIBITOR | OXIDOREDUCTASE, ALDOSE REDUCTASE, INHIBITION, DIABETES
1ah4:A (GLY16) to (SER290) PIG ALDOSE REDUCTASE, HOLO FORM | OXIDOREDUCTASE, ALDOSE REDUCTASE, INHIBITION, DIABETES
3rx2:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH SULINDAC SULFONE | ALDOSE REDUCTASE, OXIDOREDUCTASE
3rx3:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH SULINDAC | ALDOSE REDUCTASE, OXIDOREDUCTASE
4wrh:A (LEU19) to (GLY298) AKR1C3 COMPLEXED WITH BREAKDOWN PRODUCT OF N-(TERT-BUTYL)-2-(2-CHLORO- 4-(((3-MERCAPTO-5-METHYL-4H-1,2,4-TRIAZOL-4-YL)AMINO)METHYL)-6- METHOXYPHENOXY)ACETAMIDE | OXIDOREDUCTASE, INHIBITOR, COMPLEX, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4h7c:A (LEU19) to (GLY298) CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 5 IN COMPLEX WITH 1-{4-[(2-METHYL-1-PIPERIDINYL)SULFONYL]PHENYL}-2- PYRROLIDINONE | TIM-BARREL, ALDO-KETO REDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4h8n:A (ILE21) to (ASN294) CRYSTAL STRUCTURE OF CONJUGATED POLYKETONE REDUCTASE C2 FROM CANDIDA PARAPSILOSIS COMPLEXED WITH NADPH | OXIDOREDUCTASE, TIM BARREL, D-PANTOYL LACTONE
1az1:A (GLY16) to (SER290) ALRESTATIN BOUND TO C298A/W219Y MUTANT HUMAN ALDOSE REDUCTASE | OXIDOREDUCTASE, ALDO-KETO REDUCTASE, INHIBITOR BINDING
4hbk:A (GLY16) to (SER287) STRUCTURE OF THE ALDOSE REDUCTASE FROM SCHISTOSOMA JAPONICUM | ALDOSE REDUCTASE, OXIDOREDUCTASE
2p5n:B (GLY20) to (ASP297) CRYSTAL STRUCTURE OF MOUSE 17-ALPHA HYDROXYSTEROID DEHYDROGENASE IN COMPLEX WITH COENZYME NADPH | ALDO-KETO REDUCTASE, HYDROXYSTEROID DEHYDROGENASE, BINARY COMPLEX, TIM BARREL, OXIDOREDUCTASE
2bgs:A (GLY28) to (SER287) HOLO ALDOSE REDUCTASE FROM BARLEY | ALDOSE REDUCTASE, HOLOENZYME, ALDO/KETO REDUCTASE, OXIDOREDUCTASE
3s3g:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH TOLMETIN | HUMAN ALDOSE REDUCTASE, OXIDOREDUCTASE
2pd9:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE MUTANT V47I COMPLEXED WITH FIDARESTAT. | PROTEIN-LIGAND COMPLEX, TIM-BARREL, OXIDOREDUCTASE
2pdg:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE WITH URACIL-TYPE INHIBITOR AT 1.42A. | TIM BARREL, OXIDOREDUCTASE
2pdi:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE MUTANT L300A COMPLEXED WITH ZOPOLRESTAT AT 1.55 A. | TIM BARREL, OXIDOREDUCTASE
2pdk:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE MUTANT L301M COMPLEXED WITH SORBINIL. | TIM BARREL, OXIDOREDUCTASE
4hmn:A (LEU19) to (GLY298) CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 5 IN COMPLEX WITH (4-(4-CHLOROPHENYL)PIPERAZIN-1-YL)(MORPHOLINO) METHANONE (24) | TIM-BARREL, ALDO-KETO REDUCTASE, OXIDOREDUCTASE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
2pdl:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE MUTANT L301M COMPLEXED WITH TOLRESTAT. | TIM BARREL, OXIDOREDUCTASE
2pdm:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE MUTANT S302R COMPLEXED WITH ZOPOLRESTAT. | TIM BARREL, OXIDOREDUCTASE
2pdq:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE MUTANT C303D COMPLEXED WITH URACIL- TYPE INHIBITOR. | TIM BARREL, OXIDOREDUCTASE
2pdw:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE MUTANT C303D COMPLEXED WITH FIDARESTAT. | TIM BARREL, OXIDOREDUCTASE
2pdx:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE DOUBLE MUTANT S302R-C303D COMPLEXED WITH ZOPOLRESTAT. | TIM BARREL, OXIDOREDUCTASE
2pdy:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE DOUBLE MUTANT S302R-C303D COMPLEXED WITH FIDARESTAT. | TIM BARREL, OXIDOREDUCTASE
2pf8:A (GLY16) to (SER290) COMPLEX OF ALDOSE REDUCTASE WITH NADP+ AND SIMALTANEOUSLY BOUND COMPETETIVE INHIBITORS FIDARESTAT AND IDD594. CONCENTRATION OF FIDARESTAT IN SOAKING SOLUTION IS EQUAL TO CONCENTRATION OF IDD594. | OXIDOREDUCTASE, NADP, IDD594, FIDARESTAT
3f7j:A (GLY21) to (ALA260) B.SUBTILIS YVGN | ALDO-KETO REDUCTASE, OXIDOREDUCTASE
3f7j:B (GLY21) to (ALA260) B.SUBTILIS YVGN | ALDO-KETO REDUCTASE, OXIDOREDUCTASE
2pfh:A (GLY16) to (SER290) COMPLEX OF ALDOSE REDUCTASE WITH NADP+ AND SIMALTANEOUSLY BOUND COMPETETIVE INHIBITORS FIDARESTAT AND IDD594. CONCENTRATION OF FIDARESTAT IN SOAKING SOLUTION IS LESS THAN CONCENTRATION OF IDD594. | OXIDOREDUCTASE, NADP, IDD594, FIDARESTAT
1c9w:A (GLY16) to (GLY290) CHO REDUCTASE WITH NADP+ | ALPHA/BETA TIM BARREL, PROTEIN-NADP+ COMPLEX, OXIDOREDUCTASE
3fx4:A (GLY18) to (LEU292) PORCINE ALDEHYDE REDUCTASE IN TERNARY COMPLEX WITH INHIBITOR | TIM BARREL, ALDO-KETO REDUCTASE, TERNARY COMPLEX, ACETYLATION, NADP, OXIDOREDUCTASE
4igs:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH NADP+ AND JF0064 | TIM BARREL, ALDOSE REDUCTASE, OXIDOREDUCTASE, DIABETES, HALOGENATED COMPOUND, CYTOSOLIC, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4xo6:A (LEU19) to (GLY298) CRYSTAL STRUCTURE OF HUMAN 3-ALPHA HYDROXYSTEROID DEHYDROGENASE TYPE 3 IN COMPLEX WITH NADP+, 5ALPHA-ANDROSTAN-3,17-DIONE AND (3BETA, 5ALPHA)-3-HYDROXYANDROSTAN-17-ONE | ALPHA-BETA BARREL, HUMAN 3-ALPHA HDS3, AKR, AKR1C2, ALDO-KETO REDUCTASE, NADPH, OXIDOREDUCTASE
4xo6:B (VAL18) to (GLY298) CRYSTAL STRUCTURE OF HUMAN 3-ALPHA HYDROXYSTEROID DEHYDROGENASE TYPE 3 IN COMPLEX WITH NADP+, 5ALPHA-ANDROSTAN-3,17-DIONE AND (3BETA, 5ALPHA)-3-HYDROXYANDROSTAN-17-ONE | ALPHA-BETA BARREL, HUMAN 3-ALPHA HDS3, AKR, AKR1C2, ALDO-KETO REDUCTASE, NADPH, OXIDOREDUCTASE
4xo7:A (LEU19) to (GLY298) CRYSTAL STRUCTURE OF HUMAN 3-ALPHA HYDROXYSTEROID DEHYDROGENASE TYPE 3 IN COMPLEX WITH NADP+, 5ALPHA-ANDROSTAN-3,17-DIONE AND (3BETA, 5ALPHA)-3-HYDROXYANDROSTAN-17-ONE | ALPHA-BETA BARREL, HUMAN 3-ALPHA HDS3, AKR, AKR1C2, ALDO-KETO REDUCTASE, NADPH, OXIDOREDUCTASE
4xo7:B (LEU19) to (GLY298) CRYSTAL STRUCTURE OF HUMAN 3-ALPHA HYDROXYSTEROID DEHYDROGENASE TYPE 3 IN COMPLEX WITH NADP+, 5ALPHA-ANDROSTAN-3,17-DIONE AND (3BETA, 5ALPHA)-3-HYDROXYANDROSTAN-17-ONE | ALPHA-BETA BARREL, HUMAN 3-ALPHA HDS3, AKR, AKR1C2, ALDO-KETO REDUCTASE, NADPH, OXIDOREDUCTASE
3g5e:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE COMPLEXED WITH IDD 740 INHIBITOR | ALDOSE REDUCTASE, INHIBITION, DIABETES, ACETYLATION, CATARACT, CYTOPLASM, NADP, OXIDOREDUCTASE, PHOSPHOPROTEIN, POLYMORPHISM
4xvd:A (LEU19) to (GLY298) 17BETA-HSD5 IN COMPLEX WITH 4-NITRO-2-({4-[3-(TRIFLUOROMETHYL) PHENYL]PIPERAZIN-1-YL}METHYL)PHENOL | ALDO-KETO REDUCTASE INHIBITOR, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4xvd:B (VAL18) to (GLY298) 17BETA-HSD5 IN COMPLEX WITH 4-NITRO-2-({4-[3-(TRIFLUOROMETHYL) PHENYL]PIPERAZIN-1-YL}METHYL)PHENOL | ALDO-KETO REDUCTASE INHIBITOR, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4xve:A (LEU19) to (GLY298) 17BETA-HSD5 IN COMPLEX WITH 3-PENTYL-2-[(PYRIDIN-2-YLMETHYL)SULFANYL]- 7-(PYRROLIDIN-1-YLCARBONYL)QUINAZOLIN-4(3H)-ONE | ALDO-KETO REDUCTASE INHIBITOR, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3ghr:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE IN COMPLEX WITH NADP+ AND THE INHIBITOR IDD594. INVESTIGATION OF GLOBAL EFFECTS OF RADIATION DAMAGE ON PROTEIN STRUCTURE. FIRST STAGE OF RADIATION DAMAGE | OXIDOREDUCTASE, ACETYLATION, CATARACT, CYTOPLASM, NADP, PHOSPHOPROTEIN, POLYMORPHISM
3ght:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE IN COMPLEX WITH NADP+ AND THE INHIBITOR IDD594. INVESTIGATION OF GLOBAL EFFECTS OF RADIATION DAMAGE ON PROTEIN STRUCTURE. THIRD STAGE OF RADIATION DAMAGE. | OXIDOREDUCTASE, ACETYLATION, CATARACT, CYTOPLASM, NADP, PHOSPHOPROTEIN, POLYMORPHISM
3ghu:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE IN COMPLEX WITH NADP+ AND THE INHIBITOR IDD594. INVESTIGATION OF GLOBAL EFFECTS OF RADIATION DAMAGE ON PROTEIN STRUCTURE. FORTH STAGE OF RADIATION DAMAGE. | OXIDOREDUCTASE, ACETYLATION, CATARACT, CYTOPLASM, NADP, PHOSPHOPROTEIN, POLYMORPHISM
4xzh:A (GLY16) to (TYR291) CRYSTAL STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH NADP+ AND JF0048 | TIM BARREL, ALDOSE REDUCTASE, OXIDOREDUCTASE, DIABETES, HALOGENATED COMPOUND, CYTOSOLIC
4xzh:B (GLY16) to (LEU288) CRYSTAL STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH NADP+ AND JF0048 | TIM BARREL, ALDOSE REDUCTASE, OXIDOREDUCTASE, DIABETES, HALOGENATED COMPOUND, CYTOSOLIC
4xzi:A (GLY16) to (TYR291) CRYSTAL STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH NADP+ AND JF0049 | TIM BARREL, ALDOSE REDUCTASE, OXIDOREDUCTASE, DIABETES, HALOGENATED COMPOUND, CYTOSOLIC
2qxw:A (GLY16) to (SER290) PERDEUTERATED ALR2 IN COMPLEX WITH IDD594 | OXIDOREDUCTASE, NADP, IDD594, CATARACT
1pwm:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH NADP AND FIDARESTAT | ALDOSE REDUCTASE, ATOMIC RESOLUTION, X-RAY CRYSTALLOGRAPHY, TERNARY COMPLEX, INHIBITOR BINDING, OXIDOREDUCTASE
2r24:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE STRUCTURE | BETA/ALPHA-8 TIM BARREL, CATARACT, NADP, OXIDOREDUCTASE
3gug:A (LEU19) to (GLY298) CRYSTAL STRUCTURE OF AKR1C1 L308V MUTANT IN COMPLEX WITH NADP AND 3,5-DICHLOROSALICYLIC ACID | ALDO-KETO REDUCTASE, 20 ALPHA HYDROXYSTEROID DEHYDROGENASE, AKR1C1, OXIDOREDUCTASE, CYTOPLASM, NADP, POLYMORPHISM
1ef3:A (GLY16) to (TYR291) FIDARESTAT BOUND TO HUMAN ALDOSE REDUCTASE | BETA BARREL, PROTEIN-INHIBITOR COMPLEX, OXIDOREDUCTASE
1ef3:B (ILE14) to (TYR291) FIDARESTAT BOUND TO HUMAN ALDOSE REDUCTASE | BETA BARREL, PROTEIN-INHIBITOR COMPLEX, OXIDOREDUCTASE
2dux:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH ZOPOLRESTAT AFTER 3 DAYS SOAKING (3DAYS_SOAKED_1) | TIM-BARREL, OXIDOREDUCTASE
2duz:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE COMPLEXED WITH INHIBITOR ZOPOLRESTAT AFTER 3 DAYS SOAKING (3DAYS_SOAKED_2) | TIM-BARREL, OXIDOREDUCTASE
2dv0:A (GLY16) to (TYR291) HUMAN ALDOSE REDUCTASE COMPLEXED WITH ZOPOLRESTAT AFTER 6 DAYS SOAKING(6DAYS_SOAKED_2) | TIM BARREL, OXIDOREDUCTASE
4jih:A (GLY17) to (SER291) CRYSTAL STRUCTURE OF AKR1B10 COMPLEXED WITH NADP+ AND EPALRESTAT | TIM BARREL, OXIDOREDUCTASES, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4jir:A (GLY16) to (TYR291) CRYSTAL STRUCTURE OF ALDOSE REDUCTASE (AKR1B1) COMPLEXED WITH NADP+ AND EPALRESTAT | TIM BARREL, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
1eko:A (GLY16) to (TYR291) PIG ALDOSE REDUCTASE COMPLEXED WITH IDD384 INHIBITOR | ALDOSE REDUCTASE, INHIBITION, DIABETES, OXIDOREDUCTASE
1el3:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE COMPLEXED WITH IDD384 INHIBITOR | ALDOSE REDUCTASE, INHIBITION, DIABETES, OXIDOREDUCTASE
4jq1:A (VAL18) to (GLY298) AKR1C2 COMPLEX WITH NAPROXEN | OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4jq1:B (VAL18) to (GLY298) AKR1C2 COMPLEX WITH NAPROXEN | OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4jq2:A (LEU19) to (GLY298) AKR1C2 COMPLEX WITH SULINDAC | OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4jq2:B (LEU19) to (GLY298) AKR1C2 COMPLEX WITH SULINDAC | OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4jq3:A (LEU19) to (GLY298) AKR1C2 COMPLEX WITH ZOMEPIRAC | OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4jq3:B (LEU19) to (GLY298) AKR1C2 COMPLEX WITH ZOMEPIRAC | OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4jq4:A (LEU19) to (GLY298) AKR1C2 COMPLEX WITH INDOMETHACIN | OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4jq4:B (LEU19) to (GLY298) AKR1C2 COMPLEX WITH INDOMETHACIN | OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4jqa:A (LEU19) to (GLY298) AKR1C2 COMPLEX WITH MEFENAMIC ACID | OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4jqa:B (LEU19) to (GLY298) AKR1C2 COMPLEX WITH MEFENAMIC ACID | OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3h4g:A (GLY18) to (ALA291) STRUCTURE OF ALDEHYDE REDUCTASE HOLOENZYME IN COMPLEX WITH POTENT ALDOSE REDUCTASE INHIBITOR FIDARESTAT: IMPLICATIONS FOR INHIBITOR BINDING AND SELECTIVITY | TIM BARREL, ALDO-KETO REDUCTASE, TERNARY COMPLEX, NADP, OXIDOREDUCTASE
3h7u:A (SER18) to (ILE285) CRYSTAL STRUCTURE OF THE PLANT STRESS-RESPONSE ENZYME AKR4C9 | STRESS RESPONSE, ALDO-KETO REDUCTASE, NADP, DROUGHT TOLERANCE, OXIDOREDUCTASE
3u2c:A (GLY16) to (SER290) ALDOSE REDUCTASE IN COMPLEX WITH NSAID-TYPE INHIBITOR AT 1.0 A RESOLUTION | TIM BARREL, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4jtq:A (LEU19) to (GLY298) AKR1C2 COMPLEX WITH FLURBIPROFEN | OXIDO-REDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4jtq:B (LEU19) to (GLY298) AKR1C2 COMPLEX WITH FLURBIPROFEN | OXIDO-REDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4jtr:A (LEU19) to (GLY298) AKR1C2 COMPLEX WITH IBUPROFEN | OXIDO-REDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4jtr:B (LEU19) to (GLY298) AKR1C2 COMPLEX WITH IBUPROFEN | OXIDO-REDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4ys1:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE COMPLEXED WITH A LIGAND WITH AN IDD STRUCTURE (2) AT 1.07 A. | TIM BARREL, OXIDOREDUCTASE, INHIBITOR, COMPLEX
3ufy:A (LEU19) to (GLY298) AKR1C3 COMPLEX WITH R-NAPROXEN | TIM BARREL, OXIDOREDUCTASE, MULTIPLE SMALL MOLECULES
1ral:A (GLY20) to (LEU299) THREE-DIMENSIONAL STRUCTURE OF RAT LIVER 3ALPHA- HYDROXYSTEROID(SLASH)DIHYDRODIOL DEHYDROGENASE: A MEMBER OF THE ALDO-KETO REDUCTASE SUPERFAMILY | OXIDOREDUCTASE
3ug8:A (LEU19) to (GLY298) AKR1C3 COMPLEX WITH INDOMETHACIN AT PH 7.5 | TIM BARREL, OXIDOREDUCTASE, MANY SMALL MOLECULES, HORMONES, PROSTAGLANDINS
3ugr:A (LEU19) to (GLY298) AKR1C3 COMPLEX WITH INDOMETHACIN AT PH 6.8 | TIM BARREL, OXIDOREDUCTASE, MULTIPLE SMALL MOELCULES, HORMONES, PROSTAGLANDINS, NSAIDS
4yu1:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE COMPLEXED WITH SCHL12134 (3-[5-(3-NITROPHENYL)- 2-THIENYL]PROPANOIC ACID) AT 1.02 A | TIM-BARREL, OXIDOREDUCTASE, PROTEIN-LIGAND-COMPLEX
4yvp:A (LEU19) to (GLY298) CRYSTAL STRUCTURE OF AKR1C1 COMPLEXED WITH GLIBENCLAMIDE | AKR1C1 INHIBITOR, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4yvp:B (LEU19) to (GLY298) CRYSTAL STRUCTURE OF AKR1C1 COMPLEXED WITH GLIBENCLAMIDE | AKR1C1 INHIBITOR, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4yvv:A (LEU19) to (GLY298) CRYSTAL STRUCTURE OF AKR1C3 COMPLEXED WITH GLIBENCLAMIDE | AKR1C3 INHIBITOR, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4yvv:B (LEU19) to (GLY298) CRYSTAL STRUCTURE OF AKR1C3 COMPLEXED WITH GLIBENCLAMIDE | AKR1C3 INHIBITOR, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4yvx:A (LEU19) to (GLY298) CRYSTAL STRUTURE OF AKR1C3 COMPLEXED WITH GLIMEPIRIDE | AKR1C3 INHIBITOR, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4yvx:B (LEU19) to (GLY298) CRYSTAL STRUTURE OF AKR1C3 COMPLEXED WITH GLIMEPIRIDE | AKR1C3 INHIBITOR, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
2f2k:A (GLY16) to (SER290) ALDOSE REDUCTASE TERTIARY COMPLEX WITH NADPH AND DEG | INHIBITOR, GLUTATHIONE, TERTIARY COMPLEX, DICARBOXYETHYL GLUTATHIONE, OXIDOREDUCTASE
2f38:A (LEU19) to (GLY298) CRYSTAL STRUCTURE OF PROSTAGLANDIN F SYNATHASE CONTAINING BIMATOPROST | PROSTAGLANDIN F SYNTHASE, AKR1C3, PGF2ALPHA FROMATION, PGH2, BIMATOPROST, CATALYTIC MECHANISM, OXIDOREDUCTASE
2vdg:A (GLY28) to (SER287) BARLEY ALDOSE REDUCTASE 1 COMPLEX WITH BUTANOL | STRESS RESPONSE, ALDOSE REDUCTASE, ALDO-KETO REDUCTASE, NADP, AKR4C, LIGAND COMPLEX, OXIDOREDUCTASE
1ry0:A (LEU19) to (GLY298) STRUCTURE OF PROSTAGLANDIN F SYNTHASE WITH PROSTAGLANDIN D2 | PROSTAGLANDIN F SYNTHASE, AKR1C3, OXIDOREDUCTASE
1ry0:B (LEU19) to (GLY298) STRUCTURE OF PROSTAGLANDIN F SYNTHASE WITH PROSTAGLANDIN D2 | PROSTAGLANDIN F SYNTHASE, AKR1C3, OXIDOREDUCTASE
2fgb:A (LEU19) to (GLY298) CRYSTAL STRUCTURE OF HUMAN 17BET A-HYDROXYSTEROID DEHYDROGENASE TYPE 5 IN COMPLEXES WITH PEG AND NADP | (ALPHA/BETA)8 BARREL, OXIDOREDUCTASE
1ry8:A (LEU19) to (GLY298) PROSTAGLANDIN F SYNTHASE COMPLEXED WITH NADPH AND RUTIN | PROSTAGLANDIN F SYNTHASE, AKR1C3, RUTIN, OXIDOREDUCTASE
1ry8:B (LEU19) to (GLY298) PROSTAGLANDIN F SYNTHASE COMPLEXED WITH NADPH AND RUTIN | PROSTAGLANDIN F SYNTHASE, AKR1C3, RUTIN, OXIDOREDUCTASE
1s1p:A (LEU19) to (GLY298) CRYSTAL STRUCTURES OF PROSTAGLANDIN D2 11-KETOREDUCTASE (AKR1C3) IN COMPLEX WITH THE NON-STEROIDAL ANTI- INFLAMMATORY DRUGS FLUFENAMIC ACID AND INDOMETHACIN | TIM-BARREL, OXIDOREDUCTASE
1s2c:A (LEU19) to (GLY298) CRYSTAL STRUCTURES OF PROSTAGLANDIN D2 11-KETOREDUCTASE IN COMPLEX WITH THE NON-STEROIDAL ANTI-INFLAMMATORY DRUGS FLUFENAMIC ACID AND INDOMETHACIN | TIM-BARREL, OXIDOREDUCTASE
3uzw:A (ILE20) to (ALA301) CRYSTAL STRUCTURE OF 5BETA-REDUCTASE (AKR1D1) E120H MUTANT IN COMPLEX WITH NADP+ | ALDO-KETO REDUCTASE, STEROID AND BILE ACID METABOLISM, CATALYTIC TETRAD MUTANT, TIM BARREL, OXIDOREDUCTASE
3uzy:B (ILE20) to (ALA301) CRYSTAL STRUCTURE OF 5BETA-REDUCTASE (AKR1D1) E120H MUTANT IN COMPLEX WITH NADP+ AND 5BETA-DIHYDROTESTOSTERONE | ALDO-KETO REDUCTASE, STEROID AND BILE ACID METABOLISM, CATALYTIC TETRAD MUTANT, TIM BARREL, OXIDOREDUCTASE
3uzz:B (ILE20) to (ALA301) CRYSTAL STRUCTURE OF 5BETA-REDUCTASE (AKR1D1) E120H MUTANT IN COMPLEX WITH NADP+ AND DELTA4-ANDROSTENEDIONE | ALDO-KETO REDUCTASE, STEROID AND BILE ACID METABOLISM, CATALYTIC TETRAD MUTANT, TIM BARREL, OXIDOREDUCTASE
3v35:A (GLY16) to (SER290) ALDOSE REDUCTASE COMPLEXED WITH A NITRO COMPOUND | ALDOSE REDUCTASE, OXIDOREDUCTASE
3v36:A (GLY16) to (SER290) ALDOSE REDUCTASE COMPLEXED WITH GLCERALDEHYDE | ALDOSE REDUCTASE, OXIDOREDUCTASE
4zfc:A (LEU19) to (GLY298) CRYSTAL STRUCTURE OF AKR1C3 COMPLEXED WITH GLICAZIDE | AKR1C3 INHIBITOR, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4zfc:B (LEU19) to (GLY298) CRYSTAL STRUCTURE OF AKR1C3 COMPLEXED WITH GLICAZIDE | AKR1C3 INHIBITOR, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
2fvl:A (VAL18) to (LEU299) CRYSTAL STRUCTURE OF HUMAN 3-ALPHA HYDROXYSTEROID/DIHYDRODIOL DEHYDROGENASE (AKR1C4) COMPLEXED WITH NADP+ | CHLORDECONE REDUCTASE, ALDO-KETO REDUCTASE, 3ALPHA-HSD1, DD4, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE
2fvl:B (VAL18) to (LEU299) CRYSTAL STRUCTURE OF HUMAN 3-ALPHA HYDROXYSTEROID/DIHYDRODIOL DEHYDROGENASE (AKR1C4) COMPLEXED WITH NADP+ | CHLORDECONE REDUCTASE, ALDO-KETO REDUCTASE, 3ALPHA-HSD1, DD4, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE
2fvl:C (VAL18) to (ASP297) CRYSTAL STRUCTURE OF HUMAN 3-ALPHA HYDROXYSTEROID/DIHYDRODIOL DEHYDROGENASE (AKR1C4) COMPLEXED WITH NADP+ | CHLORDECONE REDUCTASE, ALDO-KETO REDUCTASE, 3ALPHA-HSD1, DD4, STRUCTURAL GENOMICS, STRUCTURAL GENOMICS CONSORTIUM, SGC, OXIDOREDUCTASE
2fz8:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE COMPLEXED WITH INHIBITOR ZOPOLRESTAT AT 1.48 A(1 DAY SOAKING). | TIM-BARREL, BACKBONE FLIP, OXIDOREDUCTASE
2fz9:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE COMPLEXED WITH INHIBITOR ZOPOLRESTAT AFTER SIX DAYS SOAKING. | TIM BARREL, BACKBONE FLIP, OXIDOREDUCTASE
2fzb:A (GLY16) to (TYR291) HUMAN ALDOSE REDUCTASE COMPLEXED WITH FOUR TOLRESTAT MOLECULES AT 1.5 A RESOLUTION. | TIM BARREL, FOUR LIGAND STRUCTURE, OXIDOREDUCTASE
2fzd:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE COMPLEXED WITH TOLRESTAT AT 1.08 A RESOLUTION. | TIM-BARREL, HIGH RESOLUTION CRYSTAL STRUCTURE, PROTEIN- LIGAND COMPLEX, OXIDOREDUCTASE
1gve:B (ALA7) to (LEU317) AFLATOXIN ALDEHYDE REDUCTASE (AKR7A1) FROM RAT LIVER | OXIDOREDUCTASE, ALDO-KETO REDUCTASE, AFLATOXIN B1, SUCCINIC SEMIALDEHYDE OXIDOREDUCTASE, AKR7 FAMILY
4l1w:A (VAL18) to (GLY298) CRYSTAL STRUCTUER OF HUMAN 3-ALPHA HYDROXYSTEROID DEHYDROGENASE TYPE 3 IN COMPLEX WITH NADP+ AND PROGESTERONE | ALPHA-BETA BARREL, HUMAN 3-ALPHA HSD3, AKR, AKR1C2,OXIDOREDUCTASE, ALDO-KETO REDUCTASE, NADPH, OXIDOREDUCTASE
4l1w:B (LEU19) to (GLY298) CRYSTAL STRUCTUER OF HUMAN 3-ALPHA HYDROXYSTEROID DEHYDROGENASE TYPE 3 IN COMPLEX WITH NADP+ AND PROGESTERONE | ALPHA-BETA BARREL, HUMAN 3-ALPHA HSD3, AKR, AKR1C2,OXIDOREDUCTASE, ALDO-KETO REDUCTASE, NADPH, OXIDOREDUCTASE
4l1x:A (VAL18) to (GLY298) CRYSTAL STRUCTUER OF HUMAN 3-ALPHA HYDROXYSTEROID DEHYDROGENASE TYPE 3 V54L MUTANT IN COMPLEX WITH NADP+ AND PROGESTERONE | ALPHA-BETA BARREL, HUMAN 3-ALPHA HSD3, AKR, AKR1C2,OXIDOREDUCTASE, ALDO-KETO REDUCTASE, NADPH, OXIDOREDUCTASE
4l1x:B (LEU19) to (GLY298) CRYSTAL STRUCTUER OF HUMAN 3-ALPHA HYDROXYSTEROID DEHYDROGENASE TYPE 3 V54L MUTANT IN COMPLEX WITH NADP+ AND PROGESTERONE | ALPHA-BETA BARREL, HUMAN 3-ALPHA HSD3, AKR, AKR1C2,OXIDOREDUCTASE, ALDO-KETO REDUCTASE, NADPH, OXIDOREDUCTASE
1t40:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH NADP AND IDD552 AT PH 5 | ALDOSE REDUCTASE, X-RAY CRYSTALLOGRAPHY, TERNARY COMPLEX, INHIBITOR BINDING, OXIDOREDUCTASE
1t41:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH NADP AND IDD552 | ALDOSE REDUCTASE, ATOMIC RESOLUTION, X-RAY CRYSTALLOGRAPHY, TERNARY COMPLEX, INHIBITOR BINDING, OXIDOREDUCTASE
4lau:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF HUMAN AR COMPLEXED WITH NADP+ AND {2-[(4- BROMOBENZYL)CARBAMOYL]-5-CHLOROPHENOXY}ACETIC ACID | TIM BARREL, OXIDOREDUCTASE, DIABETES, HALOGENATED COMPOUND, CYTOSOLIC
4laz:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF HUMAN AR COMPLEXED WITH NADP+ AND {5-CHLORO-2- [(4-IODOBENZYL)CARBAMOYL]PHENOXY}ACETIC ACID | TIM BARREL, ALDOSE REDUCTASE, OXIDOREDUCTASE, DIABETES, HALOGENATED COMPOUND, CYTOSOLIC
4lb3:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF HUMAN AR COMPLEXED WITH NADP+ AND {5-CHLORO-2- [(2-FLUORO-4-IODOBENZYL)CARBAMOYL]PHENOXY}ACETIC ACID | TIM BARREL, ALDOSE REDUCTASE, OXIDOREDUCTASE, DIABETES, HALOGENATED COMPOUND, CYTOSOLIC
4lb4:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF HUMAN AR COMPLEXED WITH NADP+ AND {2-[(4-BROMO-2, 3,5,6-TETRAFLUOROBENZYL)CARBAMOYL]-5-CHLOROPHENOXY}ACETIC ACID | TIM BARREL, ALDOSE REDUCTASE, OXIDOREDUCTASE, DIABETES, HALOGENATED COMPOUND, CYTOSOLIC
4lbr:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF HUMAN AR COMPLEXED WITH NADP+ AND {5-CHLORO-2- [(2,6-DIFLUORO-4-IODOBENZYL)CARBAMOYL]PHENOXY}ACETIC ACID | TIM BARREL, ALDOSE REDUCTASE, OXIDOREDUCTASE, DIABETES, HALOGENATED COMPOUND, CYTOSOLIC
4lbs:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF HUMAN AR COMPLEXED WITH NADP+ AND {2-[(4-BROMO-2, 6-DIFLUOROBENZYL)CARBAMOYL]-5-CHLOROPHENOXY}ACETIC ACID | TIM BARREL, ALDOSE REDUCTASE, OXIDOREDUCTASE, DIABETES, HALOGENATED COMPOUND, CYTOSOLIC
2hdj:A (LEU19) to (GLY298) CRYSTAL STRUCTURE OF HUMAN TYPE 3 3ALPHA-HYDROXYSTEROID DEHYDROGENASE IN COMPLEX WITH NADP(H) | HUMAN 3ALPHAHDS3, ALDO-KETO REDUCTASE, NADPH, AKR, AKR1C2, OXIDOREDUCTASE
2hdj:B (LEU19) to (GLY298) CRYSTAL STRUCTURE OF HUMAN TYPE 3 3ALPHA-HYDROXYSTEROID DEHYDROGENASE IN COMPLEX WITH NADP(H) | HUMAN 3ALPHAHDS3, ALDO-KETO REDUCTASE, NADPH, AKR, AKR1C2, OXIDOREDUCTASE
2he5:C (LEU19) to (LEU299) CRYSTAL STRUCTURE OF 17ALPHA-HYDROXYSTEROID DEHYDROGENASE IN BINARY COMPLEX WITH NADP(H) IN AN OPEN CONFORMATION | 17A-HSD, AKR1C21, AKR, ALDO-KETO REDUCTASE, HSD, HYDROXYSTEROID DEHYDROGENASE, OPEN CONFORMATION, OXIDOREDUCTASE
2he8:A (GLY20) to (ASP297) CRYSTAL STRUCTURE OF 17ALPHA-HYDROXYSTEROID DEHYDROGENASE IN ITS APO- FORM | 17A-HSD, AKR1C21, AKR, ALDO-KETO REDUCTASE, HSD, HYDROXYSTEROID DEHYDROGENASE, APO-FORM, OXIDOREDUCTASE
2hej:A (GLY20) to (ASP297) CRYSTAL STRUCTURE OF 17ALPHA-HYDROXYSTEROID DEHYDROGENASE IN COMPLEX WITH NADP(H) IN A CLOSED CONFORMATION | 17A-HSD, AKR1C21, AKR, ALDO-KETO REDUCTASE, HSD, HYDROXYSTEROID DEHYDROGENASE, CLOSED CONFORMATION, OXIDOREDUCTASE
2hej:B (GLY20) to (ASP297) CRYSTAL STRUCTURE OF 17ALPHA-HYDROXYSTEROID DEHYDROGENASE IN COMPLEX WITH NADP(H) IN A CLOSED CONFORMATION | 17A-HSD, AKR1C21, AKR, ALDO-KETO REDUCTASE, HSD, HYDROXYSTEROID DEHYDROGENASE, CLOSED CONFORMATION, OXIDOREDUCTASE
1hqt:A (GLY18) to (ALA291) THE CRYSTAL STRUCTURE OF AN ALDEHYDE REDUCTASE Y50F MUTANT- NADP COMPLEX AND ITS IMPLICATIONS FOR SUBSTRATE BINDING | ALPHA/BETA BARREL TIM BARREL HOLO ENZYME, OXIDOREDUCTASE
3vxg:A (ILE21) to (ASN294) CRYSTAL STRUCTURE OF CONJUGATED POLYKETONE REDUCTASE C2 FROM CANDIDA PARAPSILOSIS | OXIDOREDUCTASE, TIM BARREL, D-PANTOYL LACTONE
2hv5:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE COMPLEXED WITH INHIBITOR ZOPOLRESTAT AFTER THREE DAYS SOAKING (3DAYS_SOAKED_3) | TIM BARREL, OXIDOREDUCTASE
2hvn:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE-ZOPOLRESTAT COMPLEX OBTAINED BY COCRYSTALLISATION AFTER ONE DAY (1DAY_COCRYST) | TIM BARREL, OXIDOREDUCTASE
2hvo:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE-ZOPOLRESTAT COMPLEX OBTAINED BY COCRYSTALLISATION (10DAYS_COCRYST) | TIM BARREL, OXIDOREDUCTASE
2i16:A (GLY17) to (SER291) HUMAN ALDOSE REDUCTASE IN COMPLEX WITH NADP+ AND THE INHIBITOR IDD594 AT TEMPERATURE OF 15K | OXIDOREDUCTASE, NADP, IDD594
2i17:A (GLY17) to (SER291) HUMAN ALDOSE REDUCTASE IN COMPLEX WITH NADP+ AND THE INHIBITOR IDD594 AT TEMPERATURE OF 60K | OXIDOREDUCTASE, NADP, IDD594, 60K
3wbw:A (GLY26) to (GLN262) CRYSTAL STRUCTURE OF GOX0644 IN COMPLEX WITH NADPH | ALDO-KETO REDUCTASE (AKR), REDUCTASE, NADPH, OXIDOREDUCTASE
3wbw:B (GLY26) to (GLN262) CRYSTAL STRUCTURE OF GOX0644 IN COMPLEX WITH NADPH | ALDO-KETO REDUCTASE (AKR), REDUCTASE, NADPH, OXIDOREDUCTASE
3wbx:B (GLY26) to (GLN262) CRYSTAL STRUCTURE OF GOX0644 AT APOFORM | ALDO-KETO REDUCTASE (AKR), REDUCTASE, NADPH, OXIDOREDUCTASE
2wzm:A (GLY26) to (LEU264) CRYSTAL STRUCTURE OF A MYCOBACTERIUM ALDO-KETO REDUCTASE IN ITS APO AND LIGANDED FORM | OXIDOREDUCTASE
2wzm:B (GLY26) to (LEU264) CRYSTAL STRUCTURE OF A MYCOBACTERIUM ALDO-KETO REDUCTASE IN ITS APO AND LIGANDED FORM | OXIDOREDUCTASE
1us0:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE IN COMPLEX WITH NADP+ AND THE INHIBITOR IDD594 AT 0.66 ANGSTROM | OXIDOREDUCTASE, NADP, IDD594
2ikg:A (GLY16) to (SER290) ALDOSE REDUCTASE COMPLEXED WITH NITROPHENYL-OXADIAZOL TYPE INHIBITOR AT 1.43 A | TIM BARREL, INHIBITOR COMPLEX, ALDOSE REDUCTASE, OXIDOREDUCTASE
2ikh:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE COMPLEXED WITH NITROFURYL-OXADIAZOL INHIBITOR AT 1.55 A | TIM BARREL, INHIBITOR COMPLEX, OXIDOREDUCTASE
2iki:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE COMPLEXED WITH HALOGENATED IDD-TYPE INHIBITOR | TIM BARREL, OXIDOREDUCTASE
2ikj:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE COMPLEXED WITH NITRO-SUBSTITUTED IDD- TYPE INHIBITOR | TIM BARREL, OXIDOREDUCTASE
3wg6:A (ASN14) to (LYS291) CRYSTAL STRUCTURE OF CONJUGATED POLYKETONE REDUCTASE C1 FROM CANDIDA PARAPSILOSIS COMPLEXED WITH NADPH | AKR SUPERFAMILY, TIM BARREL, OXIDOREDUCTASE, D-PANTOYL LACTONE
3wg6:C (ALA18) to (LYS291) CRYSTAL STRUCTURE OF CONJUGATED POLYKETONE REDUCTASE C1 FROM CANDIDA PARAPSILOSIS COMPLEXED WITH NADPH | AKR SUPERFAMILY, TIM BARREL, OXIDOREDUCTASE, D-PANTOYL LACTONE
3wg6:D (ALA18) to (LYS291) CRYSTAL STRUCTURE OF CONJUGATED POLYKETONE REDUCTASE C1 FROM CANDIDA PARAPSILOSIS COMPLEXED WITH NADPH | AKR SUPERFAMILY, TIM BARREL, OXIDOREDUCTASE, D-PANTOYL LACTONE
2ine:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF ALDOSE REDUCTASE COMPLEXED WITH PHENYLACETIC ACID | TIM-BARREL, ARI, ALDO-KETO REDUCTASE, OXIDOREDUCTASE
2inz:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF ALDOSE REDUCTASE COMPLEXED WITH 2- HYDROXYPHENYLACETIC ACID | TIM-BARREL, ARI, ALDO-KETO REDUCTASE, OXIDOREDUCTASE
4mhb:A (GLY30) to (ALA270) STRUCTURE OF A PUTATIVE REDUCTASE FROM YERSINIA PESTIS | STRUCTURAL GENOMICS, CSGID, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, ALPHA AND BETA PROTEIN, TIM BETA/ALPHA BARREL, OXIDOREDUCTASE
4mhb:B (GLY30) to (ALA270) STRUCTURE OF A PUTATIVE REDUCTASE FROM YERSINIA PESTIS | STRUCTURAL GENOMICS, CSGID, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, ALPHA AND BETA PROTEIN, TIM BETA/ALPHA BARREL, OXIDOREDUCTASE
4mhb:C (GLY30) to (ALA270) STRUCTURE OF A PUTATIVE REDUCTASE FROM YERSINIA PESTIS | STRUCTURAL GENOMICS, CSGID, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, ALPHA AND BETA PROTEIN, TIM BETA/ALPHA BARREL, OXIDOREDUCTASE
4mhb:D (GLY30) to (ALA270) STRUCTURE OF A PUTATIVE REDUCTASE FROM YERSINIA PESTIS | STRUCTURAL GENOMICS, CSGID, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, ALPHA AND BETA PROTEIN, TIM BETA/ALPHA BARREL, OXIDOREDUCTASE
4mhb:E (GLY30) to (ALA270) STRUCTURE OF A PUTATIVE REDUCTASE FROM YERSINIA PESTIS | STRUCTURAL GENOMICS, CSGID, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, ALPHA AND BETA PROTEIN, TIM BETA/ALPHA BARREL, OXIDOREDUCTASE
4mhb:F (GLY30) to (ALA270) STRUCTURE OF A PUTATIVE REDUCTASE FROM YERSINIA PESTIS | STRUCTURAL GENOMICS, CSGID, CENTER FOR STRUCTURAL GENOMICS OF INFECTIOUS DISEASES, ALPHA AND BETA PROTEIN, TIM BETA/ALPHA BARREL, OXIDOREDUCTASE
2ipg:A (GLY20) to (ASP297) CRYSTAL STRUCTURE OF 17ALPHA-HYDROXYSTEROID DEHYDROGENASE MUTANT K31A IN COMPLEX WITH NADP+ AND EPI-TESTOSTERONE | 17A-HSD, AKR1C21, AKR, ALDO-KETO REDUCTASE, HSD, HYDROXYSTEROID DEHYDROGENASE, OPEN CONFORMATION, EPI-TESTOSTERONE, OXIDOREDUCTASE
2ipg:B (GLY20) to (ASP297) CRYSTAL STRUCTURE OF 17ALPHA-HYDROXYSTEROID DEHYDROGENASE MUTANT K31A IN COMPLEX WITH NADP+ AND EPI-TESTOSTERONE | 17A-HSD, AKR1C21, AKR, ALDO-KETO REDUCTASE, HSD, HYDROXYSTEROID DEHYDROGENASE, OPEN CONFORMATION, EPI-TESTOSTERONE, OXIDOREDUCTASE
2ipw:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF C298A W219Y ALDOSE REDUCTASE COMPLEXED WITH DICHLOROPHENYLACETIC ACID | TIM-BARREL, ARI, ALDO-KETO REDUCTASE, OXIDOREDUCTASE
2iq0:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF ALDOSE REDUCTASE COMPLEXED WITH HEXANOIC ACID | TIM-BARREL, ARI, ALDO-KETO REDUCTASE, OXIDOREDUCTASE
2iqd:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF ALDOSE REDUCTASE COMPLEXED WITH LIPOIC ACID | TIM-BARREL, ARI, ALDO-KETO REDUCTASE, LIPOIC, OXIDOREDUCTASE
2is7:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF ALDOSE REDUCTASE COMPLEXED WITH DICHLOROPHENYLACETIC ACID | TIM-BARREL, ARI, ALDO-KETO REDUCTASE, OXIDOREDUCTASE
1j96:A (LEU19) to (GLY298) HUMAN 3ALPHA-HSD TYPE 3 IN TERNARY COMPLEX WITH NADP AND TESTOSTERONE | ALDO-KETO REDUCTASE, STEROID METABOLISM, OXIDOREDUCTASE
1j96:B (LEU19) to (GLY298) HUMAN 3ALPHA-HSD TYPE 3 IN TERNARY COMPLEX WITH NADP AND TESTOSTERONE | ALDO-KETO REDUCTASE, STEROID METABOLISM, OXIDOREDUCTASE
1vbj:A (GLY19) to (GLY258) THE CRYSTAL STRUCTURE OF PROSTAGLANDIN F SYNTHASE FROM TRYPANOSOMA BRUCEI | TIM BARREL, OXIDOREDUCTASE
1vbj:B (GLY19) to (GLY258) THE CRYSTAL STRUCTURE OF PROSTAGLANDIN F SYNTHASE FROM TRYPANOSOMA BRUCEI | TIM BARREL, OXIDOREDUCTASE
1jez:B (HIS14) to (ALA301) THE STRUCTURE OF XYLOSE REDUCTASE, A DIMERIC ALDO-KETO REDUCTASE FROM CANDIDA TENUIS | TIM BARREL, ALDO-KETO REDUCTASE, NADPH, NADH, OXIDOREDUCTASE
2j8t:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE IN COMPLEX WITH NADP AND CITRATE AT 0.82 ANGSTROM | OXIDOREDUCTASE, NADP, CITRATE
5az0:A (ALA19) to (GLN305) CRYSTAL STRUCTURE OF ALDO-KETO REDUCTASE (AKR2E5) OF THE SILKWORM, BOMBYX MORI | ENZYME SPECIFICITY, LEPIDOPTERA, OXIDOREDUCTASE
5az1:A (ALA19) to (GLN305) CRYSTAL STRUCTURE OF ALDO-KETO REDUCTASE (AKR2E5) COMPLEXED WITH NADPH | ENZYME SPECIFICITY, LEPIDOPTERA, OXIDOREDUCTASE
1x96:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF ALDOSE REDUCTASE WITH CITRATES BOUND IN THE ACTIVE SITE | EIGHT STRANDARD ALPHA/BETA BARREL, ACTIVE SITE, THE C- TERMINAL END OF THE BARREL, OXIDOREDUCTASE
1x97:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF ALDOSE REDUCTASE COMPLEXED WITH 2R4S (STEREOISOMER OF FIDARESTAT, 2S4S) | EIGHT STRANDARD ALPHA/BETA BARREL, ACTIVE SITE, THE C- TERMINAL END OF THE BARREL, OXIDOREDUCTASE
1x98:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF ALDOSE REDUCTASE COMPLEXED WITH 2S4R (STEREOISOMER OF FIDARESTAT, 2S4S) | EIGHT STRANDARD ALPHA/BETA BARREL, ACTIVE SITE, THE C- TERMINAL END OF THE BARREL, OXIDOREDUCTASE
1xf0:A (LEU19) to (GLY298) CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 5 (AKR1C3) COMPLEXED WITH DELTA4- ANDROSTENE-3,17-DIONE AND NADP | ALPHA/BETA BARREL, BETA-HAIRPIN, OXIDOREDUCTASE
1xgd:A (ILE14) to (SER290) APO R268A HUMAN ALDOSE REDUCTASE | AKR, AKR1B1, NADPH, DIABETES, OXIDOREDUCTASE
2nvd:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE COMPLEXED WITH NOVEL NAPHTHO[1,2- D]ISOTHIAZOLE ACETIC ACID DERIVATIVE (2) | ALDOSE REDUCTASE, TIM-BARREL, PROTEIN-LIGAND COMPLEX, OXIDOREDUCTASE
1xjb:A (VAL18) to (GLY298) CRYSTAL STRUCTURE OF HUMAN TYPE 3 3ALPHA-HYDROXYSTEROID DEHYDROGENASE IN COMPLEX WITH NADP(H), CITRATE AND ACETATE MOLECULES | HUMAN 3ALPHAHDS3; ALDO-KETO REDUCTASE; NADP; INDUCE-FIT MECANISM, OXIDOREDUCTASE
1xjb:B (LEU19) to (GLY298) CRYSTAL STRUCTURE OF HUMAN TYPE 3 3ALPHA-HYDROXYSTEROID DEHYDROGENASE IN COMPLEX WITH NADP(H), CITRATE AND ACETATE MOLECULES | HUMAN 3ALPHAHDS3; ALDO-KETO REDUCTASE; NADP; INDUCE-FIT MECANISM, OXIDOREDUCTASE
4otk:A (GLY25) to (GLY265) A STRUCTURAL CHARACTERIZATION OF THE ISONIAZID MYCOBACTERIUM TUBERCULOSIS DRUG TARGET, RV2971, IN ITS UNLIGANDED FORM | TIM BARREL, OXIDOREDUCTASE
1mrq:A (VAL18) to (ASP297) CRYSTAL STRUCTURE OF HUMAN 20ALPHA-HSD IN TERNARY COMPLEX WITH NADP AND 20ALPHA-HYDROXY-PROGESTERONE | 20ALPHA-HSD, HYDROXYSTEROID DEHYDROGENASE, PROGESTERONE, TERNARY COMPLEX, OXIDOREDUCTASE
1ye6:A (GLY20) to (PHE290) CRYSTAL STRUCTURE OF THE LYS-274 TO ARG MUTANT OF CANDIDA TENUIS XYLOSE REDUCTASE (AKR2B5) BOUND TO NADP+ | BETA-ALPHA-BARREL AKR ALDO-KETO REDUCTASE COENZYME SPECIFICITY NADP, OXIDOREDUCTASE
1ynp:B (GLU15) to (ALA287) ALDO-KETO REDUCTASE AKR11C1 FROM BACILLUS HALODURANS (APO FORM) | ALDO-KETO REDUCTASE, AKR11C1, NADPH, BACILLUS HALODURANS, OXIDOREDUCTASE
1ynq:B (GLU15) to (LEU286) ALDO-KETO REDUCTASE AKR11C1 FROM BACILLUS HALODURANS (HOLO FORM) | ALDO-KETO REDUCTASE, AKR11C1, NADPH, BACILLUS HALODURANS, OXIDOREDUCTASE
1z3n:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE IN COMPLEX WITH NADP+ AND THE INHIBITOR LIDORESTAT AT 1.04 ANGSTROM | OXIDOREDUCTASE, NADP+, LIDORESTAT
4prt:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE COMPLEXED WITH SCHL12221 ({2-[5-(3- NITROPHENYL)FURAN-2-YL]PHENYL}ACETIC ACID) AT 0.96 A | TIM BARREL, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3ld5:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE MUTANT T113S COMPLEXED WITH IDD594 | TIM BARREL, T113S MUTANT, OXIDOREDUCTASE, NADP, PHOSPHOPROTEIN, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3lep:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE MUTANT T113C IN COMPLEX WITH IDD388 | TIM BARREL, T113C MUTANT, OXIDOREDUCTASE, NADP, PHOSPHOPROTEIN, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
1z8a:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE COMPLEXED WITH NOVEL SULFONYL- PYRIDAZINONE INHIBITOR | PROTEIN-LIGAND COMPLEX, TIM-BARREL, DOUBLE CONFORMATION, OXIDOREDUCTASE
1z89:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE COMPLEXED WITH NOVEL SULFONYL- PYRIDAZINONE INHIBITOR | SULFONYL-PYRIDAZINONE, TIM-BARREL, OXIDOREDUCTASE
4puu:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE COMPLEXED WITH A LIGAND WITH AN IDD STRUCTURE (2-(2-CARBAMOYL-5-FLUORO-PHENOXY)ACETIC ACID) AT 1.14 A | TIM BARREL, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4puw:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE COMPLEXED WITH A LIGAND WITH AN IDD STRUCTURE (2-[5-FLUORO-2-(PROP-2-YNYLCARBAMOYL)PHENOXY]ACETIC ACID) AT 1.12 A | TIM BARREL, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
1zq5:A (LEU19) to (GLY298) CRYSTAL STRUCTURE OF HUMAN ANDROGENIC 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 5 IN COMPLEXED WITH A POTENT INHIBITOR EM1404 | (ALPHA/BETA)8 BARREL, OXIDOREDUCTASE
3lqg:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE MUTANT T113A COMPLEXED WITH IDD388 | T113A MUTANT, OXIDOREDUCTASE, NADP, PHOSPHOPROTEIN, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
3lql:A (GLY17) to (SER291) HUMAN ALDOSE REDUCTASE MUTANT T113A COMPLEXED WITH IDD 594 | T113A MUTANT, OXIDOREDUCTASE, TIM BARREL, NADP, PHOSPHOPROTEIN, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
1zua:X (GLY17) to (SER291) CRYSTAL STRUCTURE OF AKR1B10 COMPLEXED WITH NADP+ AND TOLRESTAT | ALPHA-BETA BARREL, ALDO-KETO REDUCTASE, OXIDOREDUCTASE
4q7b:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE COMPLEXED WITH A LIGAND WITH AN IDD STRUCTURE ([2-(BENZYLCARBAMOYL)-5-FLUOROPHENOXY]ACETIC ACID) AT 1.19 A | TIM BARREL, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3lz5:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE MUTANT T113V COMPLEXED WITH IDD594 | T113V MUTANT, OXIDOREDUCTASE, TIM BARREL, NADP, PHOSPHOPROTEIN, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4qbx:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE COMPLEXED WITH A LIGAND WITH AN IDD STRUCTURE ({5-FLUORO-2-[(3-NITROBENZYL)CARBAMOYL]PHENOXY}ACETIC ACID) AT 0.98 A | TIM BARREL, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3m64:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE MUTANT T113V COMPLEXED WITH IDD393 | T113V MUTANT, TIM-BARREL, NADP, PHOSPHOPROTEIN, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
2acq:A (GLY16) to (SER290) AN ANION BINDING SITE IN HUMAN ALDOSE REDUCTASE: MECHANISTIC IMPLICATIONS FOR THE BINDING OF CITRATE, CACODYLATE, AND GLUCOSE-6-PHOSPHATE | OXIDOREDUCTASE
2acr:A (GLY16) to (SER290) AN ANION BINDING SITE IN HUMAN ALDOSE REDUCTASE: MECHANISTIC IMPLICATIONS FOR THE BINDING OF CITRATE, CACODYLATE, AND GLUCOSE-6- PHOSPHATE | OXIDOREDUCTASE
2acs:A (GLY16) to (SER290) AN ANION BINDING SITE IN HUMAN ALDOSE REDUCTASE: MECHANISTIC IMPLICATIONS FOR THE BINDING OF CITRATE, CACODYLATE, AND GLUCOSE-6-PHOSPHATE | OXIDOREDUCTASE
2acu:A (GLY16) to (SER290) TYROSINE-48 IS THE PROTON DONOR AND HISTIDINE-110 DIRECTS SUBSTRATE STEREOCHEMICAL SELECTIVITY IN THE REDUCTION REACTION OF HUMAN ALDOSE REDUCTASE: ENZYME KINETICS AND THE CRYSTAL STRUCTURE OF THE Y48H MUTANT ENZYME | OXIDOREDUCTASE
3bcj:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF ALDOSE REDUCTASE COMPLEXED WITH 2S4R (STEREOISOMER OF FIDARESTAT, 2S4S) AT 0.78 A | ALDO-KETO REDUCTASES, DIABETES, DRUG DESIGN, POLYL PATHWAY, ACETYLATION, CATARACT, CYTOPLASM, NADP, OXIDOREDUCTASE, POLYMORPHISM
4qr6:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE COMPLEXED WITH A LIGAND WITH AN IDD STRUCTURE (2-[2-(1,3-BENZOTHIAZOL-2-YLMETHYLCARBAMOYL)-5-FLUORO-PHENOXY]ACETIC ACID) AT 1.05 A | TIM BARREL, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4qx4:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE COMPLEXED WITH A LIGAND WITH A NEW SCAFFOLD AT 1.26 A | TIM BARREL,OXIDOREDUCTASE, TIM BARREL, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4qxi:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF HUMAN AR COMPLEXED WITH NADP+ AND AK198 | TIM BARREL, ALDOSE REDUCTASE, OXIDOREDUCTASE, DIABETES, HALOGENATED COMPOUND, CYTOSOLIC
3bur:A (GLY22) to (ALA301) CRYSTAL STRUCTURE OF DELTA(4)-3-KETOSTEROID 5-BETA-REDUCTASE IN COMPLEX WITH NADP AND TESTOSTERONE. RESOLUTION: 1.62 A. | 5BETA-REDUCTASE; CATALYTIC TETRAD; TESTOSTERONE; NADP, BILE ACID CATABOLISM, DISEASE MUTATION, LIPID METABOLISM, OXIDOREDUCTASE, STEROID METABOLISM
3caq:B (GLY22) to (ALA301) CRYSTAL STRUCTURE OF 5BETA-REDUCTASE (AKR1D1) IN COMPLEX WITH NADPH | 5B-REDUCTASE, 5BETA-REDUCTASE, 5B-RED, AKR1D1, AKR, ALDO- KETO REDUCTASE, NADP, ANDROSTENEDIONE, NADPH, 5B-DHP, SUBSTRATE INHIBITION, BILE ACID CATABOLISM, CYTOPLASM, DISEASE MUTATION, LIPID METABOLISM, OXIDOREDUCTASE, STEROID METABOLISM
3cas:B (GLY22) to (ALA301) CRYSTAL STRUCTURE OF 5BETA-REDUCTASE (AKR1D1) IN COMPLEX WITH NADP+ AND 4-ANDROSTENEDIONE | 5B-REDUCTASE, 5BETA-REDUCTASE, 5B-RED, AKR1D1, AKR, ALDO- KETO REDUCTASE, NADP, ANDROSTENEDIONE, NADPH, SUBSTRATE INHIBITION, BILE ACID CATABOLISM, CYTOPLASM, DISEASE MUTATION, LIPID METABOLISM, OXIDOREDUCTASE, STEROID METABOLISM
3cav:B (GLY22) to (ALA301) CRYSTAL STRUCTURE OF 5BETA-REDUCTASE (AKR1D1) IN COMPLEX WITH NADP+ AND 5BETA-PREGNAN-3,20-DIONE | 5B-REDUCTASE, 5BETA-REDUCTASE, 5B-RED, AKR1D1, AKR, ALDO- KETO REDUCTASE, NADP, ANDROSTENEDIONE. NADPH, MECHANISM, BILE ACID CATABOLISM, CYTOPLASM, DISEASE MUTATION, LIPID METABOLISM, OXIDOREDUCTASE, STEROID METABOLISM
3nty:A (LEU19) to (GLY298) CRYSTAL STRUCTURE OF AKR1C1 IN COMPLEX WITH NADP AND 5-PHENYL,3- CHLOROSALICYLIC ACID | ALDO-KETO REDUCTASE, 20 ALPHA HYDROXYSTEROID DEHYDROGENASE, AKR1C1, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4rpq:A (GLY16) to (TYR291) HUMAN ALDOSE REDUCTASE COMPLEXED WITH A LIGAND WITH AN IDD STRUCTURE AT 1.20 A (1) | TIM BARREL, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3cv6:A (LEU19) to (ASP297) THE CRYSTAL STRUCTURE OF MOUSE 17-ALPHA HYDROXYSTEROID DEHYDROGENASE GG225.226PP MUTANT IN COMPLEX WITH INHIBITOR AND COFACTOR NADP+. | ALDO-KETO REDUCTASE, HYDROXYSTEROID DEHYDROGENASE, TERNARY COMPLEX, HEXESTROL, LIPID METABOLISM, NADP, OXIDOREDUCTASE, PHOSPHOPROTEIN, STEROID METABOLISM
3cv6:B (GLY20) to (ASP297) THE CRYSTAL STRUCTURE OF MOUSE 17-ALPHA HYDROXYSTEROID DEHYDROGENASE GG225.226PP MUTANT IN COMPLEX WITH INHIBITOR AND COFACTOR NADP+. | ALDO-KETO REDUCTASE, HYDROXYSTEROID DEHYDROGENASE, TERNARY COMPLEX, HEXESTROL, LIPID METABOLISM, NADP, OXIDOREDUCTASE, PHOSPHOPROTEIN, STEROID METABOLISM
3cv7:A (LEU16) to (ALA291) CRYSTAL STRUCTURE OF PORCINE ALDEHYDE REDUCTASE TERNARY COMPLEX | TIM BARREL, ALDO-KETO REDUCTASE, TERNARY COMPLEX, ACETYLATION, NADP, OXIDOREDUCTASE
3o0k:A (GLY37) to (LYS277) CRYSTAL STRUCTURE OF ALDO/KETO REDUCTASE FROM BRUCELLA MELITENSIS | SSGCID, ALS COLLABORATIVE CRYSTALLOGRAPHY, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, OXIDOREDUCTASE
3o0k:B (GLY37) to (LYS277) CRYSTAL STRUCTURE OF ALDO/KETO REDUCTASE FROM BRUCELLA MELITENSIS | SSGCID, ALS COLLABORATIVE CRYSTALLOGRAPHY, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, OXIDOREDUCTASE
3o0k:C (GLY37) to (LYS277) CRYSTAL STRUCTURE OF ALDO/KETO REDUCTASE FROM BRUCELLA MELITENSIS | SSGCID, ALS COLLABORATIVE CRYSTALLOGRAPHY, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, OXIDOREDUCTASE
3o0k:D (GLY37) to (LEU278) CRYSTAL STRUCTURE OF ALDO/KETO REDUCTASE FROM BRUCELLA MELITENSIS | SSGCID, ALS COLLABORATIVE CRYSTALLOGRAPHY, STRUCTURAL GENOMICS, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, OXIDOREDUCTASE
3d3f:A (GLY21) to (ALA260) CRYSTAL STRUCTURE OF YVGN AND COFACTOR NADPH FROM BACILLUS SUBTILIS | ALDO-KETO REDUCTASE, OXIDOREDUCTASE
3d3f:B (GLY21) to (ALA260) CRYSTAL STRUCTURE OF YVGN AND COFACTOR NADPH FROM BACILLUS SUBTILIS | ALDO-KETO REDUCTASE, OXIDOREDUCTASE
3onb:A (GLY16) to (SER290) BOND BREAKAGE AND RELOCATION OF A COVALENTLY BOUND BROMINE OF IDD594 IN A COMPLEX WITH HAR T113A MUTANT AFTER EXTENSIVE RADIATION DOSE | RADIATION DAMAGE, T113A MUTANT, TIM BARREL, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
3onc:A (GLY16) to (SER290) BOND BREAKAGE AND RELOCATION OF A COVALENTLY BOUND BROMINE OF IDD594 IN A COMPLEX WITH HAR T113A MUTANT AFTER MODERATE RADIATION DOSE | RADIATION DAMAGE, T113A MUTANT, TIM BARREL, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
5ha7:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE IN COMPLEX WITH NADP+ AND WY14643 IN SPACE GROUP P212121 | ALPHA/BETA BARREL, OXIDOREDUCTASE
5ha7:B (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE IN COMPLEX WITH NADP+ AND WY14643 IN SPACE GROUP P212121 | ALPHA/BETA BARREL, OXIDOREDUCTASE
4dbs:A (LEU19) to (GLY298) CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 5 (AKR1C3) IN COMPLEX WITH NADP+ AND 3'-[(4-NITRONAPHTHALEN-1-YL) AMINO]BENZOIC ACID | CASTRATE RESISTANT PROSTATE CANCER, AKR1C3 SELECTIVE INHIBITOR, TIM BARREL, STEROID METABOLISM, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4dbs:B (LEU19) to (GLY298) CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 5 (AKR1C3) IN COMPLEX WITH NADP+ AND 3'-[(4-NITRONAPHTHALEN-1-YL) AMINO]BENZOIC ACID | CASTRATE RESISTANT PROSTATE CANCER, AKR1C3 SELECTIVE INHIBITOR, TIM BARREL, STEROID METABOLISM, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4dz5:A (LEU19) to (GLY298) W227F ACTIVE SITE MUTANT OF AKR1C3 | TIM BARREL, OXIDOREDUCTASE
3q65:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE IN COMPLEX WITH NADP+ IN SPACE GROUP P212121 | ALPHA/BETA BARREL, OXIDOREDUCTASE
3q65:B (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE IN COMPLEX WITH NADP+ IN SPACE GROUP P212121 | ALPHA/BETA BARREL, OXIDOREDUCTASE
3q67:A (GLY16) to (TYR291) HUMAN ALDOSE REDUCTASE C298S MUTANT IN COMPLEX WITH NADP+ IN SPACE GROUP P212121 | ALPHA/BETA BARREL, OXIDOREDUCTASE
3q67:B (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE C298S MUTANT IN COMPLEX WITH NADP+ IN SPACE GROUP P212121 | ALPHA/BETA BARREL, OXIDOREDUCTASE
4f40:A (GLY21) to (ALA268) X-RAY CRYSTAL STRUCTURE OF APO PROSTAGLANDIN F SYNTHASE FROM LEISHMANIA MAJOR FRIEDLIN | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, NADP, OXIDOREDUCTASE
4f40:B (GLY21) to (ALA268) X-RAY CRYSTAL STRUCTURE OF APO PROSTAGLANDIN F SYNTHASE FROM LEISHMANIA MAJOR FRIEDLIN | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, NADP, OXIDOREDUCTASE
4fa3:A (LEU19) to (GLY298) CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 5 IN COMPLEX WITH (R)-1-(NAPHTHALEN-2-YLSULFONYL)PIPERIDINE-3- CARBOXYLIC ACID (86) | TIM-BARREL, ALDO-KETO REDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4fal:A (LEU19) to (GLY298) CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 5 IN COMPLEX WITH 3-((3,4-DIHYDROISOQUINOLIN-2(1H)-YL)SULFONYL)-N- METHYLBENZAMIDE (80) | ALDO-KETO REDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4fam:A (LEU19) to (GLY298) CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 5 IN COMPLEX WITH 3-((3,4-DIHYDROISOQUINOLIN-2(1H)-YL)SULFONYL)BENZOIC ACID (17) | ALDO-KETO REDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4fam:B (VAL18) to (GLY298) CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 5 IN COMPLEX WITH 3-((3,4-DIHYDROISOQUINOLIN-2(1H)-YL)SULFONYL)BENZOIC ACID (17) | ALDO-KETO REDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3r43:A (LEU19) to (GLY298) AKR1C3 COMPLEXED WITH MEFENAMIC ACID | TIM BARREL, ALDO-KETO REDUCTASE, NITRO REDUCTASE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
3r58:A (LEU19) to (GLY298) AKR1C3 COMPLEX WITH NAPROXEN | TIM BARREL, ALDO-KETO REDUCTASE, NITRO REDUCTASE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
3r6i:A (LEU19) to (GLY298) AKR1C3 COMPLEX WITH MECLOFENAMIC ACID | TIM BARREL, ALDO-KETO REDUCTASE, NITRO REDUCTASE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
3r8g:A (LEU19) to (GLY298) AKR1C3 COMPLEX WITH IBUPROFEN | TIM BARREL, IBUPROFEN, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3r8h:A (LEU19) to (GLY298) AKR1C3 COMPLEX WITH ZOMEPIRAC | TIM BARREL, ZOMEPIRAC, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
5jh1:A (GLY17) to (GLU280) CRYSTAL STRUCTURE OF THE APO FORM OF AKR4C7 FROM MAIZE | ALDO-KETO REDUCTASE SUPERFAMILY, AKR4C SUBFAMILY, OXIDOREDUCTASE
5jh2:A (GLY17) to (ILE281) CRYSTAL STRUCTURE OF THE HOLO FORM OF AKR4C7 FROM MAIZE | ALDO-KETO REDUCTASE SUPERFAMILY, AKR4C SUBFAMILY, OXIDOREDUCTASE
4g5d:A (GLY21) to (ALA268) X-RAY CRYSTAL STRUCTURE OF PROSTAGLANDIN F SYNTHASE FROM LEISHMANIA MAJOR FRIEDLIN BOUND TO NADPH | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, OXIDOREDUCTASE
4g5d:B (GLY21) to (ALA268) X-RAY CRYSTAL STRUCTURE OF PROSTAGLANDIN F SYNTHASE FROM LEISHMANIA MAJOR FRIEDLIN BOUND TO NADPH | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, OXIDOREDUCTASE
4ga8:A (GLY17) to (SER291) HUMAN AKR1B10 MUTANT V301L COMPLEXED WITH NADP+ AND SORBINIL | TIM BARREL, ALDO-KETO REDUCTASE, OXIDOREDUCTASE
4gac:B (GLY18) to (ALA291) HIGH RESOLUTION STRUCTURE OF MOUSE ALDEHYDE REDUCTASE (AKR1A4) IN ITS APO-FORM | TIM BARREL, ALDHEYDE REDUCTASE AKR1A4, SMAR1, OXIDOREDUCTASE
4gie:A (GLY20) to (GLU262) CRYSTAL STRUCTURE OF PROSTAGLANDIN F SYNTHASE FROM TRYPANOSOMA CRUZI BOUND TO NADP | STRUCTURAL GENOMICS, NIAID, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, SEATTLE STRUCTURAL GENOMICS CENTER FOR INFECTIOUS DISEASE, SSGCID, CHAGAS DISEASE, PROSTAGLANDIN D2, TRYPANOSOMIASIS, EUKARYOTIC PATHOGEN, PARASITE, NADP+, NADPH, RUTIN, BIMATOPROST, OXIDOREDUCTASE
4gqg:A (GLY17) to (SER291) CRYSTAL STRUCTURE OF AKR1B10 COMPLEXED WITH NADP+ | ALPHA-BETA TIM BARREL, NADP-DEPENDANT OXIDOREDUCTASE, NADP+, OXIDOREDUCTASE
2alr:A (LEU15) to (ALA290) ALDEHYDE REDUCTASE | OXIDOREDUCTASE, TIM-BARREL
1afs:A (VAL18) to (ASP297) RECOMBINANT RAT LIVER 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE (3-ALPHA-HSD) COMPLEXED WITH NADP AND TESTOSTERONE | OXIDOREDUCTASE, NAD
1afs:B (VAL18) to (ASP297) RECOMBINANT RAT LIVER 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE (3-ALPHA-HSD) COMPLEXED WITH NADP AND TESTOSTERONE | OXIDOREDUCTASE, NAD
3rx4:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH SULINDAC SULFIDE | ALDOSE REDUCTASE, OXIDOREDUCTASE
2pdc:A (GLY16) to (TYR291) HUMAN ALDOSE REDUCTASE MUTANT F121P COMPLEXED WITH IDD393. | TIM BARREL, OXIDOREDUCTASE
2pdn:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE MUTANT S302R COMPLEXED WITH URACIL- TYPE INHIBITOR. | TIM BARREL, OXIDOREDUCTASE
2pev:A (GLY16) to (SER290) COMPLEX OF ALDOSE REDUCTASE WITH NADP+ AND SIMALTANEOUSLY BOUND COMPETETIVE INHIBITORS FIDARESTAT AND IDD594. CONCENTRATION OF FIDARESTAT IN SOAKING SOLUTION EXCEEDS CONCENTRATION OF IDD594. | OXIDOREDUCTASE, NADP, IDD594, FIDARESTAT
3fjn:A (GLY20) to (ASP297) THE CRYSTAL STRUCTURE OF 17-ALPHA HYDROXYSTEROID DEHYDROGENASE Y224D MUTANT. | ALDO-KETO REDUCTASE, 17-ALPHA-HYDROXYSTEROID DEHYDROGENASE, CYTOPLASM, LIPID METABOLISM, NADP, OXIDOREDUCTASE, PHOSPHOPROTEIN, STEROID METABOLISM
3fjn:B (GLY20) to (ASP297) THE CRYSTAL STRUCTURE OF 17-ALPHA HYDROXYSTEROID DEHYDROGENASE Y224D MUTANT. | ALDO-KETO REDUCTASE, 17-ALPHA-HYDROXYSTEROID DEHYDROGENASE, CYTOPLASM, LIPID METABOLISM, NADP, OXIDOREDUCTASE, PHOSPHOPROTEIN, STEROID METABOLISM
3ghs:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE IN COMPLEX WITH NADP+ AND THE INHIBITOR IDD594. INVESTIGATION OF GLOBAL EFFECTS OF RADIATION DAMAGE ON PROTEIN STRUCTURE. SECOND STAGE OF RADIATION DAMAGE. | OXIDOREDUCTASE, ACETYLATION, CATARACT, CYTOPLASM, NADP, PHOSPHOPROTEIN, POLYMORPHISM
1q13:A (VAL18) to (ASP297) CRYSTAL STRUCTURE OF RABBIT 20ALPHA HYROXYSTEROID DEHYDROGENASE IN TERNARY COMPLEX WITH NADP AND TESTOSTERONE | 20ALPHA-HSD, HYDROXYSTEROID DEHYDROGENASE, ALDO-KETO REDUCTASE, TIM- BARREL, AKR, TESTOSTERONE, TERNARY COMPLEX, OXIDOREDUCTASE
1q13:B (VAL18) to (SER298) CRYSTAL STRUCTURE OF RABBIT 20ALPHA HYROXYSTEROID DEHYDROGENASE IN TERNARY COMPLEX WITH NADP AND TESTOSTERONE | 20ALPHA-HSD, HYDROXYSTEROID DEHYDROGENASE, ALDO-KETO REDUCTASE, TIM- BARREL, AKR, TESTOSTERONE, TERNARY COMPLEX, OXIDOREDUCTASE
1q5m:A (VAL18) to (ASP297) BINARY COMPLEX OF RABBIT 20ALPHA-HYDROXYSTEROID DEHYDROGENASE WITH NADPH | NADPH, HSD, HYDROXYSTEROID DEHYDROGENASE, ALDO-KETO REDUCTASE, OXIDOREDUCTASE
1q5m:B (VAL18) to (ASP297) BINARY COMPLEX OF RABBIT 20ALPHA-HYDROXYSTEROID DEHYDROGENASE WITH NADPH | NADPH, HSD, HYDROXYSTEROID DEHYDROGENASE, ALDO-KETO REDUCTASE, OXIDOREDUCTASE
1s1r:A (LEU19) to (GLY298) CRYSTAL STRUCTURES OF PROSTAGLANDIN D2 11-KETOREDUCTASE (AKR1C3) IN COMPLEX WITH THE NON-STEROIDAL ANTI- INFLAMMATORY DRUGS FLUFENAMIC ACID AND INDOMETHACIN | TIM-BARREL, OXIDOREDUCTASE
1s2a:A (LEU19) to (GLY298) CRYSTAL STRUCTURES OF PROSTAGLANDIN D2 11-KETOREDUCTASE IN COMPLEX WITH THE NON-STEROIDAL ANTI-INFLAMMATORY DRUGS FLUFENAMIC ACID AND INDOMETHACIN | TIM-BARREL, OXIDOREDUCTASE
1ihi:A (VAL18) to (GLY298) CRYSTAL STRUCTURE OF HUMAN TYPE III 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE/BILE ACID BINDING PROTEIN (AKR1C2) COMPLEXED WITH NADP+ AND URSODEOXYCHOLATE | ALPHA-BETA BARREL, TERNARY COMPLEX, PROTEIN-NADP-BILE ACID COMPLEX, OXIDOREDUCTASE
1ihi:B (VAL18) to (GLY298) CRYSTAL STRUCTURE OF HUMAN TYPE III 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE/BILE ACID BINDING PROTEIN (AKR1C2) COMPLEXED WITH NADP+ AND URSODEOXYCHOLATE | ALPHA-BETA BARREL, TERNARY COMPLEX, PROTEIN-NADP-BILE ACID COMPLEX, OXIDOREDUCTASE
3wby:B (GLY26) to (ASP264) CRYSTAL STRUCTURE OF GOX0644 D53A MUTANT IN COMPLEX WITH NADPH | ALDO-KETO REDUCTASE (AKR), REDUCTASE, NADPH, OXIDOREDUCTASE
2wzt:A (GLY26) to (ASP269) CRYSTAL STRUCTURE OF A MYCOBACTERIUM ALDO-KETO REDUCTASE IN ITS APO AND LIGANDED FORM | OXIDOREDUCTASE
2wzt:B (GLY26) to (ASP268) CRYSTAL STRUCTURE OF A MYCOBACTERIUM ALDO-KETO REDUCTASE IN ITS APO AND LIGANDED FORM | OXIDOREDUCTASE
2ipf:A (GLY20) to (ASP297) CRYSTAL STRUCTURE OF 17ALPHA-HYDROXYSTEROID DEHYDROGENASE IN COMPLEX WITH NADP+ AND EPI-TESTOSTERONE | 17A-HSD, AKR1C21, AKR, ALDO-KETO REDUCTASE, HSD, HYDROXYSTEROID DEHYDROGENASE, OPEN CONFORMATION, EPI-TESTOSTERONE, OXIDOREDUCTASE
2ipf:B (GLY20) to (ASP297) CRYSTAL STRUCTURE OF 17ALPHA-HYDROXYSTEROID DEHYDROGENASE IN COMPLEX WITH NADP+ AND EPI-TESTOSTERONE | 17A-HSD, AKR1C21, AKR, ALDO-KETO REDUCTASE, HSD, HYDROXYSTEROID DEHYDROGENASE, OPEN CONFORMATION, EPI-TESTOSTERONE, OXIDOREDUCTASE
2ipj:A (LEU19) to (GLY298) CRYSTAL STRUCTURE OF H3ALPHA-HYDROXYSTEROID DEHYDROGENASE TYPE 3 MUTANT Y24A IN COMPLEX WITH NADP+ AND EPI-TESTOSTERONE | 3A-HSD, AKR1C21, AKR, ALDO-KETO REDUCTASE, HSD, HYDROXYSTEROID DEHYDROGENASE, OPEN CONFORMATION, EPI-TESTOSTERONE, OXIDOREDUCTASE
2ipj:B (LEU19) to (GLY298) CRYSTAL STRUCTURE OF H3ALPHA-HYDROXYSTEROID DEHYDROGENASE TYPE 3 MUTANT Y24A IN COMPLEX WITH NADP+ AND EPI-TESTOSTERONE | 3A-HSD, AKR1C21, AKR, ALDO-KETO REDUCTASE, HSD, HYDROXYSTEROID DEHYDROGENASE, OPEN CONFORMATION, EPI-TESTOSTERONE, OXIDOREDUCTASE
2isf:A (GLY16) to (SER290) CRYSTAL STRUCTURE OF C298A W219Y ALDOSE REDUCTASE COMPLEXED WITH PHENYLACETIC ACID | TIM-BARREL, ARI, ALDO-KETO REDUCTASE, OXIDOREDUCTASE
4nkc:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE COMPLEXED WITH SCHL7764 AT 1.12 A | TIM BARREL, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3lbo:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE MUTANT T113C COMPLEXED WITH IDD594 | TIM BARREL, T113C MUTANT OXIDOREDUCTASE, NADP, PHOSPHOPROTEIN, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4pr4:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE COMPLEXED WITH SCHL7802 AT 1.06 A | TIM BARREL, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4prr:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE COMPLEXED WITH SCHL7815 ((3-[3-(5-NITROFURAN-2- YL)PHENYL]PROPANOIC ACID)AT 1.01 A | TIM BARREL,OXIDOREDUCTASE, TIM BARREL, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3lz3:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE MUTANT T113S COMPLEXED WITH IDD388 | T113S MUTANT, TIM BARREL, OXIDOREDUCTASE, NADP, PHOSPHOPROTEIN, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3m4h:A (GLY16) to (SER290) HUMAN ALDOSE REDUCTASE MUTANT T113V COMPLEXED WITH IDD388 | T113V MUTANT, OXIDOREDUCTASE, NADP, PHOSPHOPROTEIN, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
3b3d:A (GLY21) to (ALA264) B.SUBTILIS YTBE | ALDO-KETO REDUCTASE, OXIDOREDUCTASE
3b3d:B (GLY21) to (ALA264) B.SUBTILIS YTBE | ALDO-KETO REDUCTASE, OXIDOREDUCTASE
3b3d:C (GLY21) to (ALA264) B.SUBTILIS YTBE | ALDO-KETO REDUCTASE, OXIDOREDUCTASE
3c3u:A (VAL18) to (GLY298) CRYSTAL STRUCTURE OF AKR1C1 IN COMPLEX WITH NADP AND 3,5- DICHLOROSALICYLIC ACID | ALDO-KETO REDUCTASE, 20 ALPHA HYDROXYSTEROID DEHYDROGENASE, AKR1C1, CYTOPLASM, NADP, OXIDOREDUCTASE
4dbu:A (LEU19) to (ASP297) CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 5 (AKR1C3) IN COMPLEX WITH NADP+ AND 3-((4 -(TRIFLUOROMETHYL)PHENYL) AMINO)BENZOIC ACID | CASTRATE RESISTANT PROSTATE CANCER, AKR1C3 SELECTIVE INHIBITOR, TIM BARREL, STEROID METABOLISM, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4dbu:B (VAL18) to (GLY298) CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 5 (AKR1C3) IN COMPLEX WITH NADP+ AND 3-((4 -(TRIFLUOROMETHYL)PHENYL) AMINO)BENZOIC ACID | CASTRATE RESISTANT PROSTATE CANCER, AKR1C3 SELECTIVE INHIBITOR, TIM BARREL, STEROID METABOLISM, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4dbw:A (LEU19) to (GLY298) CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 5 (AKR1C3) IN COMPLEX WITH NADP+ AND 2'-DESMETHYL-INDOMETHACIN | CASTRATE RESISTANT PROSTATE CANCER, AKR1C3 SELECTIVE INHIBITOR, TIM BARREL, STEROID METABOLISM, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
4dbw:B (LEU19) to (GLY298) CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 5 (AKR1C3) IN COMPLEX WITH NADP+ AND 2'-DESMETHYL-INDOMETHACIN | CASTRATE RESISTANT PROSTATE CANCER, AKR1C3 SELECTIVE INHIBITOR, TIM BARREL, STEROID METABOLISM, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3r7m:A (LEU19) to (GLY298) AKR1C3 COMPLEX WITH SULINDAC | TIM BARREL, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
3r94:A (LEU19) to (GLY298) AKR1C3 COMPLEX WITH FLURBIPROFEN | TIM BARREL, FLURBIPROFEN, OXIDOREDUCTASE, OXIDOREDUCTASE- OXIDOREDUCTASE INHIBITOR COMPLEX
4gq0:A (GLY17) to (SER291) CRYSTAL STRUCTURE OF AKR1B10 COMPLEXED WITH NADP+ AND CAFFEIC ACID PHENETHYL ESTER | ALPHA-BETA TIM BARREL, NADP-DEPENDANT OXIDOREDUCTASE, CAFFEIC ACID PHENETHYL ESTER AND NADP+, OXIDOREDUCTASE