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# Program: MUSTANG-Lite v0.1: A  Multiple structural alignment algorithm
# Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey
# Rundate: Sat Jul 23 06:10:08 2005
# Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/HOMSTRAD_Datasets/results/dhfr.html
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#====================================
# Aligned_structures: 4
#   1: 1dhfa.pdb
#   2: 3dfr.pdb
#   3: 4dfra.pdb
#   4: 8dfr.pdb
#
# Length:        192
# Identity:       22/192 ( 11.5%)  (Calculated as the percentage of conserved columns in the alignment.)
# Similarity:     55/192 ( 28.6%)  (Calculated as the percentage of semi-conserved columns in the alignment)
# Gaps:           39/192 ( 20.3%)  (Calculated as the percentage of columns with atleast one gap.)

#===========================================ALIGNMENT START=========================================


1dhfa.pdb               1  ---LNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSI   57
3dfr.pdb                1  ---TAFLWAQNRNGLIGK-DGHLPWHLPDDLHYFRAQTV-------GKIMVVGRRTYESF   49
4dfra.pdb               1  --MISLIAALAVDRVIGM-ENAMPWNLPADLAWFKRNTL-------DKPVIMGRHTWESI   50
8dfr.pdb                1  VRSLNSIVAVCQNMGIGKDGNLPWPPLRNEYKYFQRMTSTSHVEGKQNAVIMGKKTWFSI   60
                                 i A   n  IGk        L     yF r T           vimG  Tw Si

1dhfa.pdb              58  PEKNRPLKGRINLVLSRE-LKEPPQGAHFLSRSLDDALKLTEQPELANKV-DMVWIVGGS  115
3dfr.pdb               50  P--KRPLPERTNVVLTHQEDY-QAQ-GAVVVHDVAAVFAYAKQH-----LDQELVIAGGA  100
4dfra.pdb              51  G---RPLPGRKNIILSSQ-PG-TDD-RVTWVKSVDEAIAACG----D--V-PEIMVIGGG   97
8dfr.pdb               61  PEKNRPLKDRINIVLSRE-LKEAPKGAHYLSKSLDDALALLDSPELKSKV-DMVWIVGGT  118
                           p   RPL  R N vLs                s d a a          v     i GG 

1dhfa.pdb             116  SVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEE----KG  171
3dfr.pdb              101  QIFTAFKDDV--DTLLVTRLAGSFEGDTKMIPLNWDDFTKVS-S----RTVEDT-NPA--  150
4dfra.pdb              98  RVYEQFLPKA--QKLYLTHIDAEVEGDTHFPDYEPDDWESVF-S----EFHDADAQ--NS  148
8dfr.pdb              119  AVYKAAMEKPINHRLFVTRILHEFESDTFFPEIDYKDFKLLTEYPGVPADIQEE----DG  174
                            vy           L vTri   fE DT fp     d                       

1dhfa.pdb             172  IKYKFEVYEKN-  182
3dfr.pdb              151  LTHTYEVWQKKA  162
4dfra.pdb             149  HSYCFKILERR-  159
8dfr.pdb              175  IQYKFEVYQKSV  186
                             y fev  k  


#=========================================ALIGNMENT END=============================================
#LEGEND:
#
# Colours indicate the chemical nature of the amino acid;
# Red         = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W}
# Blue        = Acidic,{D,E}
# Magenta     = Basic,{K,R} and
# Green       = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}.
#
# The "markup row" below each stretch of the multiple alignment is used to mark completely conserved
# residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment.
#
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