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# Program: MUSTANG-Lite v0.1: A Multiple structural alignment algorithm
# Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey
# Rundate: Sat Jul 23 12:51:14 2005
# Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/HOMSTRAD_Datasets/results/ace.html
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#====================================
# Aligned_structures: 6
# 1: 1clea.pdb
# 2: 1maha.pdb
# 3: 1thg.pdb
# 4: 1trh.pdb
# 5: 2ace.pdb
# 6: 2bce.pdb
#
# Length: 660
# Identity: 75/660 ( 11.4%) (Calculated as the percentage of conserved columns in the alignment.)
# Similarity: 101/660 ( 15.3%) (Calculated as the percentage of semi-conserved columns in the alignment)
# Gaps: 229/660 ( 34.7%) (Calculated as the percentage of columns with atleast one gap.)
#===========================================ALIGNMENT START=========================================
1clea.pdb 1 -----APTAKLANGDTITGLNAI------INEAFLGIPFAEPPVGNLRFKDPVPYSGS-L 48
1maha.pdb 1 ED-PQ-LLVRV-RGGQLRGIRLKAP-G-GPVSAFLGIPFAEPPVGSRRFMPPEPKRPW-S 54
1thg.pdb 1 -----APTAVLNGNEVISGVLEG------KVDTFKGIPFADPPLNDLRFKHPQPFTGS-Y 48
1trh.pdb 1 -----APTATLANGDTITGLNAI------INEAFLGIPFAEPPVGNLRFKDPVPYSGS-L 48
2ace.pdb 1 ---SE-LLVNT-KSGKVMGTRVPVL-S-SHISAFLGIPFAEPPVGNMRFRRPEPKKPW-S 52
2bce.pdb 1 --AKL-GSVYT-EGGFVEGVNKKLSLFGDSVDIFKGIPFAAAP---KALEKPERHPGWQ- 52
G F GIPFA pP rf P p
1clea.pdb 49 NGQKFTSYGPSCMQQNPEG---------TF-----EENLGKTALDLVMQSKVFQ--A-VL 91
1maha.pdb 55 GVLDATTFQNVCYQYVDT----------L---YPG------FEGTEM--------WNPNR 87
1thg.pdb 49 QGLKANDFSPACMQLDPGNSLTLLDKAL-GLAK--VIPEEFRGPLYDMA-------KGTV 98
1trh.pdb 49 DGQKFTSYGPSCMQQNPE----------GTYEE--NLPKAALDLVMQSK-----VFEAVS 91
2ace.pdb 53 GVWNASTYPNNCQQYVDE----------Q---FPG------FSGSEM--------WNPNR 85
2bce.pdb 53 GTLKAKSFKKRCLQATLT------------------------------------Q---DS 73
C Q
1clea.pdb 92 -PQSEDCLTINVVRPPG----TKAGANLPVMLWIFGGG-F----EIGS--PTIFPPAQMV 139
1maha.pdb 88 -ELSEDCLYLNVWTPYP----R-PASPTPVLIWIYGGG-F----YSGAASLDVYDGRFLA 136
1thg.pdb 99 -SMNEDCLYLNVFRPAG----TKPDAKLPVMVWIYGGAFVY--G---S--SAAYPGNSYV 146
1trh.pdb 92 -PSSEDCLTINVVRPPG----TKAGANLPVMLWIFGGG-F----EVGG--TSTFPPAQMI 139
2ace.pdb 86 -EMSEDCLYLNIWVPSP----R-PK-STTVMVWIYGGG-F----YSGSSTLDVYNGKYLA 133
2bce.pdb 74 TYGNEDCLYLNIWVPQGRKEV---SHDLPVMIWIYGGAFLMGL----S--NYLYDGEEIA 124
EDCL N P pVm WI GG
1clea.pdb 140 TKSVLMGKPIIHVAVNYRVASWGFLAGD---DIKAEGSGNAGLKDQRLGMQWVADNIAGF 196
1maha.pdb 137 QVE-----GAVLVSMNYRVGTFGFLALPGSREA----PGNVGLLDQRLALQWVQENIAAF 187
1thg.pdb 147 KESINMGQPVVFVSINYRTGPFGFLGGD---AITAEGNTNAGLHDQRKGLEWVSDNIANF 203
1trh.pdb 140 TKSIAMGKPIIHVSVNYRVSSWGFLAGD---EIKAEGSANAGLKDQRLGMQWVADNIAAF 196
2ace.pdb 134 YTE-----EVVLVSLSYRVGAFGFLALHGSQEA----PGNVGLLDQRMALQWVHDNIQFF 184
2bce.pdb 125 TRG-----NVIVVTFNYRVGPLGFLSTG-DSNL----PGNYGLWDQHMAIAWVKRNIEAF 174
V nYRv GFL N GL DQr WV NI F
1clea.pdb 197 GGDPSKVTIFGESAGSMSVLCHLIWN---DGDNTYKGKPLFRAGIMQSGAMVPSDPVDGT 253
1maha.pdb 188 GGDPMSVTLFGESAGAASVGMHILSLPSR---------SLFHRAVLQSGTPN------GP 232
1thg.pdb 204 GGDPDKVMIFGESAGAMSVAHQLIAY---GGDNTYNGKKLFHSAILQSGGPLPYHDS-SS 259
1trh.pdb 197 GGDPTKVTIFGESAGSMSVMCHILWN---DGDNTYKGKPLFRAGIMQSGAMVPSDAVDGI 253
2ace.pdb 185 GGDPKTVTIFGESAGGASVGMHILSPGSR---------DLFRRAILQSGSPN------CP 229
2bce.pdb 175 GGDPDQITLFGESAGGASVSLQTLSPYNK---------GLIKRAISQSGVGL------CP 219
GGDP vt FGESAG SV Lf i QSG
1clea.pdb 254 ---------YGNEIYDLFVSSAGCG-SAS--DKLACLRSASSDTLLDATN----NTPGFL 297
1maha.pdb 233 WATVSAG--EARRRATLLARLVGC----NDTELIACLRTRPAQDLVDHEW----HVL--P 280
1thg.pdb 260 -----VGPD---ISYNRFAQYAGCDTSASANDTLECLRSKSSSVLHDAQN----SYD--L 305
1trh.pdb 254 ---------YGNEIFDLLASNAGCG-SAS--DKLACLRGVSSDTLEDATN----NTPGFL 297
2ace.pdb 230 WASVSVA--EGRRRAVELGRNLNCNLN-SDEELIHCLREKKPQELIDVEW----NVL--P 280
2bce.pdb 220 WAIQQ----DPLFWAKRIAEKVGCPVD-DTSKMAGCLKITDPRALTLAYKLPLG-----S 269
gC CLr L d
1clea.pdb 298 --AYSS-LR-----LSYLPRPDGKNITDDMYKLVR-DGKYASVPVIIGDQNDEGTVFGLS 348
1maha.pdb 281 QE--SI-FR-----FSFVPVVDGDFLSDTPEALIN-TGDFQDLQVLVGVVKDEGSYFLVY 331
1thg.pdb 306 --KDLFGLL--PQFLGFGPRPDGNIIPDAAYELFR-SGRYAKVPYISGNQEDEGTAFAPV 360
1trh.pdb 298 --AYSS-LR-----LSYLPRPDGVNITDDMYALVR-EGKYANIPVIIGDQNDEGTFFGTS 348
2ace.pdb 281 FD--SI-FR-----FSFVPVIDGEFFPTSLESMLN-SGNFKKTQILLGVNKDEGSFFLLY 331
2bce.pdb 270 --TEYP-KLHY---LSFVPVIDGDFIPDDPVNLYANA---ADVDYIAGTNDMDGHLFVGM 320
s P DG d l G deG F
1clea.pdb 349 SL---------N--VTTNAQARAYFKQSFIHASDAEIDTLMAAYPQ-DITQGSPFDTGIF 396
1maha.pdb 332 GVPGFSK-DNE-SL-ISRAQFLAGVRIGVPQASDLAAEAVVLHYTDWLH----------P 378
1thg.pdb 361 AL---------N--ATTTPHVKKWLQYIFYDASEASIDRVLSLYPQ-TLSVGSPFRTGIL 408
1trh.pdb 349 SL---------N--VTTDAQAREYFKQSFVHASDAEIDTLMTAYPG-DITQGSPFDTGIL 396
2ace.pdb 332 GAPGFSK-DSE-SK-ISREDFMSGVKLSVPHANDLGLDAVTLQYTDWMD----------D 378
2bce.pdb 321 DVPAIN-SN--KQD-VTEEDFYKLVSGLTVTKGLRGAQATYEVYTE---------PWAQD 367
a Y
1clea.pdb 397 -NAITPQFKRISAVLGDLAFIHARRYFLNHF-Q-G--GTKYSFLSKQL--S-G-L-PIMG 446
1maha.pdb 379 E-DPTHLRDAMSAVVGDHNVVCPVAQLAGRLAAQG--ARVYAYIFEHRASTLTWP-LWMG 434
1thg.pdb 409 -NALTPQFKRVAAILSDMLFQSPRRVMLSAT-K-D--VNRWTYLSTHL--H-NLV-PFLG 459
1trh.pdb 397 -NALTPQFKRISAVLGDLGFTLARRYFLNHY-T-G--GTKYSFLSKQL--S-G-L-PVLG 446
2ace.pdb 379 N-NGIKNRDGLDDIVGDHNVICPLMHFVNKYTKFG--NGTYLYFFNHRASNLVWP-EWMG 434
2bce.pdb 368 S-SQETRKKTMVDLETDILFLIPTKIAVAQHKSHAKSANTYTYLFSQPSRM-PIYPKWMG 425
D y G
1clea.pdb 447 TFHANDIVWQDYL--------L----GSGSVIYNNAFIAFATDLDPNT---A--GLL-VN 488
1maha.pdb 435 VPHGYEIEFIFGLPLDPS-LNYTTEERIFAQRLMKYWTNFARTGDPNDPRD---SKS-PQ 489
1thg.pdb 460 TFHGNELIFQFNV--------N----IGPANSYLRYFISFANHHDPNV---G--TNL-LQ 501
1trh.pdb 447 TFHSNDIVFQDYL--------L----GSGSLIYNNAFIAFATDLDPNT---A--GLL-VK 488
2ace.pdb 435 VIHGYEIEFVFGLPLVKE-LNYTAEEEALSRRIMHYWATFAKTGNPN----------ESK 483
2bce.pdb 426 ADHADDLQYVFGKPFAT-PLGYRAQDRTVSKAMIAYWTNFARTGDPNT---GHSTVP-AN 480
H FA dPN
1clea.pdb 489 WPKYTSSSQSGNNLMMINALGLY--TGKDNFRTAGYDALMTNPSSF-F-----------V 534
1maha.pdb 490 WPPYTT---AAQQYVSLNLKPLE--VRRG-LRAQTCAFWNRFLPKL-LSAT--------- 533
1thg.pdb 502 WDQYTD---EGKEMLEIHMTDNV--MRTDDYRIEGISNFETDVNLYG------------- 543
1trh.pdb 489 WPEYTSSSQSGNNLMMINALGLY--TGKDNFRTAGYDALFSNPPSF-F-----------V 534
2ace.pdb 484 WPLFTT---KEQKFIDLNTEPMK--VHQR-LRVQMCVFWNQFLPKL-LNAT--------- 527
2bce.pdb 481 WDPYTL---EDDNYLEINKQM-DSNSMKLHLRTNYLQFWTQTYQAL-PT--VTPVVIGF- 532
W yT n R
#=========================================ALIGNMENT END=============================================
#LEGEND:
#
# Colours indicate the chemical nature of the amino acid;
# Red = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W}
# Blue = Acidic,{D,E}
# Magenta = Basic,{K,R} and
# Green = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}.
#
# The "markup row" below each stretch of the multiple alignment is used to mark completely conserved
# residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment.
#
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