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# Program: MUSTANG-Lite v0.1: A  Multiple structural alignment algorithm
# Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey
# Rundate: Fri Jul 22 23:41:42 2005
# Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/HOMSTRAD_Datasets/results/Topoisomerase_I.html
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#====================================
# Aligned_structures: 2
#   1: 1a35a.pdb
#   2: 1ois.pdb
#
# Length:        225
# Identity:      113/225 ( 50.2%)  (Calculated as the percentage of conserved columns in the alignment.)
# Similarity:    113/225 ( 50.2%)  (Calculated as the percentage of semi-conserved columns in the alignment)
# Gaps:           13/225 (  5.8%)  (Calculated as the percentage of columns with atleast one gap.)

#===========================================ALIGNMENT START=========================================


1a35a.pdb               1  --IKWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKE   58
1ois.pdb                1  DTIKWVTLKHNGVIFPPPYQPLPSHIKLYYDGKPVDLPPQAEEVAGFFAALLESDHAKNP   60
                             IKW  L H G  F PPY PLP   K YYDGK   L P AEEVA FFA  L        

1a35a.pdb              59  IFRKNFFKDWRKEMTNEEKN------IITNLSKCDFTQMSQYFKAQTEARKQMSKEEKLK  112
1ois.pdb               61  VFQKNFFNDFLQVLK--ESGGPLNGIEIKEFSRCDFTKMFDYFQLQKEQKKQL---EKKQ  115
                            F KNFF D        E         I   S CDFT M  YF  Q E  KQ    EK  

1a35a.pdb             113  IKEENEKLLKEYGFCIMDNHKERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINC  172
1ois.pdb              116  IRLEREKFEEDYKFCELDGRREQVGNFKVEPPDLFRGRGAHPKTGKLKRRVNPEDIVLNL  175
                           I  E EK    Y FC  D   E   NFK EPP LFRGRG HPK G LKRR  PEDI  N 

1a35a.pdb             173  SKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNP  217
1ois.pdb              176  SKDAPVPPAPEGHKWGEIRHDNTVQWLAMWRENIFNSFKYVRLAA  220
                           SKDA VP  P GHKW E RHDN V WL  W ENI  S KY  L  


#=========================================ALIGNMENT END=============================================
#LEGEND:
#
# Colours indicate the chemical nature of the amino acid;
# Red         = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W}
# Blue        = Acidic,{D,E}
# Magenta     = Basic,{K,R} and
# Green       = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}.
#
# The "markup row" below each stretch of the multiple alignment is used to mark completely conserved
# residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment.
#
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