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# Program: MUSTANG-Lite v0.1: A  Multiple structural alignment algorithm
# Authors: A. S. Konagurthu, A. M. Lesk, J. C. Whisstock, and P. J. Stuckey
# Rundate: Sat Jul 23 08:57:32 2005
# Report_file: /mnt/EXTRA_STORAGE/MUSTANG_RESULTS/HOMSTRAD_Datasets/results/PK.html
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#====================================
# Aligned_structures: 4
#   1: 1a3xa.pdb
#   2: 1a49a.pdb
#   3: 1pkla.pdb
#   4: 1pkya.pdb
#
# Length:        530
# Identity:      137/530 ( 25.8%)  (Calculated as the percentage of conserved columns in the alignment.)
# Similarity:    249/530 ( 47.0%)  (Calculated as the percentage of semi-conserved columns in the alignment)
# Gaps:           82/530 ( 15.5%)  (Calculated as the percentage of columns with atleast one gap.)

#===========================================ALIGNMENT START=========================================


1a3xa.pdb               1  -----------MSRLERLTSLNVV-AGSDLRRTSIIGTIGPKTNNPETLVALRKAGLNIV   48
1a49a.pdb               1  IQTQQLHAAMADTFLEHMCRLDIDSAPITARNTGIICTIGPASRSVETLKEMIKSGMNVA   60
1pkla.pdb               1  ------------SQLAHNLTLSIFDPVANYRAARIICTIGPSTQSVEALKGLIQSGMSVA   48
1pkya.pdb               1  -----------------------------MKKTKIVCTIGPKTESEEMLAKMLDAGMNVM   31
                                                         r t IicTIGP t s E L      Gmnv 

1a3xa.pdb              49  RMNFSHGSYEYHKSVIDNARKSEELYP------GRPLAIALDTKGPEIRTGTTT--NDVD  100
1a49a.pdb              61  RMNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAV-ALDTKGPEIRTGLIKGSGTAE  119
1pkla.pdb              49  RMNFSHGSHEYHQTTINNVRQAAAELG------VNIAI-ALDTKGPEIRTGQFV--GG-D   98
1pkya.pdb              32  RLNFSHGDYAEHGQRIQNLRNVMSKTG------KTAAI-LLDTKGPEIRTMKLE--GGND   82
                           RmNFSHG  eyH   I N R                a  aLDTKGPEIRTg     g  d

1a3xa.pdb             101  YPIPPNHEMIFTTDDKYAKACDDKIMYVDYKNITKVISAGRIIYVDDGVLSFQVLEVVDD  160
1a49a.pdb             120  VELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVDVGSKVYVDDGLISLQVKQK-GP  178
1pkla.pdb              99  AVMERGATCYVTTDPAFADKGTKDKFYIDYQNLSKVVRPGNYIYIDDGILILQVQSHEDE  158
1pkya.pdb              83  VSLKAGQTFTFTTDKS--VIGNSEMVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAI-EG  139
                                g t   TtD              dY n  kv   G   yvDDG    qV      

1a3xa.pdb             161  KTLKVKALNAGKICSHKGVNLPGTDVDLPALSEKDKEDLRFGVKNGVHMVFASFIRTAND  220
1a49a.pdb             179  DFLVTEVENGGFLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKAAD  238
1pkla.pdb             159  QTLECTVTNSHTISDRRGVNLPGCDVDLPAVSAKDRVDLQFGVEQGVDMIFASFIRSAEQ  218
1pkya.pdb             140  NKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSD  199
                             l   v N g     kGVNLPG  vdLPA seKD  DL FGveqgVdmvfASFIR a d

1a3xa.pdb             221  VLTIREVL-GEQGKDVKIIVKIENQQGVNNFDEILKVTDGVMVARGDLGIEIPAPEVLAV  279
1a49a.pdb             239  VHEVRKIL-GEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLA  297
1pkla.pdb             219  VGDVRKAL-GPKGRDIMIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVA  277
1pkya.pdb             200  VIEIREHLKAHGGENIHIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFA  259
                           V   R  L g  G  i II KIEN  Gv nfDeIle sDGiMVARGDLG EIPae V  a

1a3xa.pdb             280  QKKLIAKSNLAGKPVICATQMLESMTYNPRPTRAEVSDVGNAILDGADCVMLSGETAKGN  339
1a49a.pdb             298  QKMIIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGD  357
1pkla.pdb             278  QKILISKCNVAGKPVICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGK  337
1pkya.pdb             260  QKMMIEKCIRARKVVITATMMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGK  319
                           QK  I kcn AgKpVIcATqMLeSM  nPRPTRAE sDVaNA ldGaDcvMLSGEtAKG 

1a3xa.pdb             340  YPINAVTTMAETAVIAEQAIAYLPNYDDMRNCTPK---PTSTTETVAASAVAAVFEQKAK  396
1a49a.pdb             358  YPLEAVRMQHLIAREAEAAMFHRKLFEELARSSSH---STDLMEAMAMGSVEASYKCLAA  414
1pkla.pdb             338  YPNEVVQYMARICLEAQSALNEYVFFNSIKKLQHI---PMSADEAVCSSAVNSVYETKAK  394
1pkya.pdb             320  YPLEAVSIMATICERTDRVMNS-------------RLEKLRITEAVCRGAVETAEKLDAP  366
                           YP eaV  ma i   a  a                        Eav   aV       A 

1a3xa.pdb             397  AIIVLSTSGTTPRLVSKYRPNCPIILVTRCPRAARFSHLYRGVFPFVFE-KE---TD---  449
1a49a.pdb             415  ALIVLTESGRSAHQVARYRPRAPIIAVTRNHQTARQAHLYRGIFPVVCKDPVQEAWAE--  472
1pkla.pdb             395  AMVVLSNTGRSARLVAKYRPNCPIVCVTTRLQTCRQLNITQGVESVFFDADK------LG  448
1pkya.pdb             367  LIVVATQGGKSARAVRKYFPDATILALTTNEKTAHQLVLSKGVVPQLVKE----------  416
                           a  Vl   G sar V kYrP  pI  vT    tarq  l  Gv p               

1a3xa.pdb             450  ---DVEARINFGIEKAKEFGILKKGDTYVSIQG--------NTLQVSTV-  487
1a49a.pdb             473  ---DVDLRVNLAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP  519
1pkla.pdb             449  HDEGKEHRVAAGVEFAKSKGYVQTGDYCVVIHAA-------NQTRILLVE  491
1pkya.pdb             417  -ITSTDDFYRLGKELALQSGLAHKGDVVVMVSGALVPSGTTNTASVHVL-  464
                                  r   g e ak  G   kGD  v   g        Nt  v  v 


#=========================================ALIGNMENT END=============================================
#LEGEND:
#
# Colours indicate the chemical nature of the amino acid;
# Red         = small hydrophobic including aromatic,{A,F,I,L,M,P,V,W}
# Blue        = Acidic,{D,E}
# Magenta     = Basic,{K,R} and
# Green       = Basic amino acids with hydroxyl groups and/or amine groups {C,G,H,N,Q,S,T,Y}.
#
# The "markup row" below each stretch of the multiple alignment is used to mark completely conserved
# residue (denoted in UPPERCASE) and semi-conserved reside ( denoted in lowercase) in a column of the alignment.
#
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